Chemotherapy And Radiotherapy Of Gastrointestinal Tumors

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Radiation Therapy for Gastrointestinal Cancers

Author : Theodore Hong
Publisher : Springer
ISBN 13 : 3319431153
Total Pages : 245 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Radiation Therapy for Gastrointestinal Cancers by : Theodore Hong

Download or read book Radiation Therapy for Gastrointestinal Cancers written by Theodore Hong and published by Springer. This book was released on 2017-02-13 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date, hands-on manual offers clear guidance on contouring and treatment planning for both standard and advanced radiation therapy in patients with gastrointestinal cancers and simultaneously draws together the available relevant clinical data for each type of cancer with a view to driving treatment recommendations. The full range of malignancies is covered, including esophageal, gastric, pancreatic, hepatic, biliary, colon, rectal, and anal cancers and pelvic recurrences. Additional chapters are devoted to stereotactic body radiation therapy (SBRT) to the liver for metastatic disease. The management of gastrointestinal cancers with radiation therapy has become increasingly complex. Specifically, the emergence of new techniques such as SBRT and intensity-modulated radiation therapy (IMRT) has further increased the need to understand how to contour targets and organs at risk, how to perform safe treatment planning, and when to apply these technologies. In this context, Radiation Therapy for Gastrointestinal Cancers represents an ideal reference for both established clinical radiation oncologists and radiation oncology residents.

Chemotherapy and Radiotherapy of Gastrointestinal Tumors

Author : H.O. Klein
Publisher : Springer Science & Business Media
ISBN 13 : 3642816819
Total Pages : 138 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Chemotherapy and Radiotherapy of Gastrointestinal Tumors by : H.O. Klein

Download or read book Chemotherapy and Radiotherapy of Gastrointestinal Tumors written by H.O. Klein and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Attempts to influence survival of patients with colorectal cancer (CRC) by adjuvant chemotherapy are limited by the variability of survival in different prognostic groups [4] and the paucity of drugs that have shown activity in the advanced disease [10]. Of the few drugs which are active in the advanced disease, only 5-fluorouracil (5-FU) and razoxane «±1,2-bis(3,4-dioxopiperazin-1-yl)propane) are suitable for long-term adjuvant treatment [2, 9]. 5-FU has been widely and intensively studied as adjuvant chemotherapy in CRC [7], but there is no unanimity that it has even the marginal influence on survival that has been claimed [3, 10]. Razoxane has not previously been tested for adjuvant or maintenance treatment in CRC. It has however a number of biological activities which might be thought useful in the treatment of residual or minimal tumours [1] and which might therefore make it useful as an adjuvant. Thus it specifically prevents tumour dissemination and metastases in some tumours and normalizes the neovasculature which the tumours induce [6, 8, 11]. The drug is not cytotoxic in the usual sense, does not affect non-dividing cells, and only blocks cell division during a brief period of the cell cycle in late G and/or early mitosis [12]. It does so non-selectively and most cells capable of 2 division examined so far have been affected by the drug. Even affected cells however are not destroyed immediately, but may increase in size and become multinucleate [5].

Gastrointestinal Cancer

Author : Ralph R., Jr. Dobelbower
Publisher : Springer Science & Business Media
ISBN 13 : 3642836577
Total Pages : 301 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Gastrointestinal Cancer by : Ralph R., Jr. Dobelbower

Download or read book Gastrointestinal Cancer written by Ralph R., Jr. Dobelbower and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primary malignant tumors of the gastrointestinal tract account for 23% of all invasive cancers and 24% of all the deaths in 1988. In the United States, the American Cancer Society estimates that there will be 227500 new cases of gastrointestinal malignancy di agnosed, with 122350 deaths. This includes 9800 new cases of carcinomas of the esopha gus, 24800 carcinomas of the stomach, 2500 new cases of malignant tumors of the small intestine, 105000 new cases of tumors of the large intestine, and 42000 new cases of car cinoma of the rectum, 14000 new cases involving the liver and biliary passages, 27000 new cases of carcinoma of the pancreas, and 2400 other unspecified digestive tract ma lignancies. This combined incidence is second only to the number of new cases of lung cancer. Bleeding from the gastrointestinal tract represents one of the earliest findings with re gard to malignancy of the gastrointestinal tract. In general, personal or family history of colon and rectal cancer, personal or family history of polyps in the colon or rectum, or inflammatory bowel disease are high risk factors with regard to tumors in these loca tions. Dietary behavior is also important in that a diet high in fat and/or low in fiber content may be a significant causative factor.

Controversies in Gastrointestinal Tumor Therapy

Author : T. Wiegel
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805576900
Total Pages : 132 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Controversies in Gastrointestinal Tumor Therapy by : T. Wiegel

Download or read book Controversies in Gastrointestinal Tumor Therapy written by T. Wiegel and published by Karger Medical and Scientific Publishers. This book was released on 2004-01-01 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume discusses diagnostic and therapeutic strategies including current controversial issues in the management of gastrointestinal tumors. Special emphasis is given to rectal and pancreatic cancer. The first part presents the latest diagnostic developments for rectal cancer with a focus on the role of preoperative radiotherapy and radio-chemotherapy. Also considered is the surgical technique of total mesorectal excision. Recurrent rectal cancer is another important issue under discussion. A large section of the book is devoted to the diagnosis and interdisciplinary treatment of pancreatic cancer. Controversies regarding the role of adjuvant radiochemotherapy are presented in detail. The final part is dedicated to the treatment of liver metastases and describes the results of surgical resection and new therapeutic approaches such as in situ ablation and radiosurgery. Offering an interdisciplinary perspective on gastrointestinal tumor therapy, this book will be of great value to surgeons and radiation oncologists. It will also be appreciated by other clinicians involved in the care of patients with gastrointestinal tumors.

Gastrointestinal Malignancies

Author : Suzanne Russo
Publisher : Springer
ISBN 13 : 3319649000
Total Pages : 373 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Gastrointestinal Malignancies by : Suzanne Russo

Download or read book Gastrointestinal Malignancies written by Suzanne Russo and published by Springer. This book was released on 2017-12-30 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a practical guide on how best to incorporate advanced radiation therapy techniques into the multimodality treatment of a wide range of gastrointestinal tumors, including esophageal cancer, gastric cancer, hepatobiliary malignancies (primary and metastatic liver tumors, intrahepatic, perihilar, and extrahepatic cholangiocarcinomas, and gallbladder cancer), pancreatic cancer, colorectal cancer, and carcinoma of the anal canal. Practical considerations when treating patients with external beam radiation therapy, intensity-modulated radiation therapy, particle therapy, and stereotactic body radiation therapy are clearly explained. Detailed attention is devoted to the safety and efficacy of radiotherapy in combination with current and emerging systemic therapies (chemotherapy, immunotherapy, and biologic agents), surgery, and ablative therapy, and the advantages and disadvantages of alternative treatment approaches for different tumor types are carefully evaluated. The book will benefit radiation oncologists, medical and surgical oncologists, medical physicists, medical dosimetrists, and other oncology professionals.

Handbook of Gastrointestinal Cancers

Author : Tanios Bekaii-Saab, MD
Publisher : Springer Publishing Company
ISBN 13 : 0826138136
Total Pages : 516 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Handbook of Gastrointestinal Cancers by : Tanios Bekaii-Saab, MD

Download or read book Handbook of Gastrointestinal Cancers written by Tanios Bekaii-Saab, MD and published by Springer Publishing Company. This book was released on 2019-08-12 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Gastrointestinal Cancers is a practical guide to the management of colorectal, pancreatic, hepatocellular, gastric, and esophageal cancers as well as other cancers of the upper and lower gastrointestinal tract. Edited by a multidisciplinary group of oncologists from leading institutions, this book is an essential day-to-day reference for evidence-based treatment and patient care. The handbook focuses on treatment strategies and approaches to cancerous gastrointestinal tumors that are transforming the recent oncological landscape, including expert-given guidance on methods such as neoadjuvant and adjuvant chemotherapy, surgical transplant, radiation therapy, molecular diagnostic testing leading to molecularly targeted therapy, and immunotherapy. With so many advances in the current field, it is increasingly difficult for early-career practitioners to grasp the entirety of practices and for seasoned oncologists to keep up with newly approved therapies, side effects to treatments, and special clinical management considerations, but this handbook addresses it all. Organized by major gastrointestinal disease sites and featuring “How I Treat” case vignettes from world experts for common and uncommon management considerations, the handbook brings an experience-based perspective to these tough-to-treat areas. The treatment strategies and applications set forth in the chapters are pertinent to situations and decision-making encountered in practice. Handbook of Gastrointestinal Cancers is a valuable resource for medical oncologists, radiation oncologists, and surgeons treating and managing gastrointestinal cancers as well as trainees in medical, radiation, and surgical oncology programs needing an accessible point of care resource. KEY FEATURES: Provides treatment plans and recommendations for each stage of a range of gastrointestinal cancers, including colorectal, pancreatic, and hepatocellular cancers plus more Includes “How I Treat” patient vignettes told from the physician’s point of view within each clinical chapter Outlines special considerations for the elderly and for survivors of gastrointestinal cancers Highlights important clinical guidance on nutritional and palliative concerns commonly seen in patients with gastrointestinal cancers

Gastrointestinal Oncology

Author : Janusz Jankowski
Publisher : John Wiley & Sons
ISBN 13 : 1444300156
Total Pages : 752 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Gastrointestinal Oncology by : Janusz Jankowski

Download or read book Gastrointestinal Oncology written by Janusz Jankowski and published by John Wiley & Sons. This book was released on 2009-01-26 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal Oncology: A Critical Multidisciplinary Team Approach is the first evidence-based reference text designed for the multidisciplinary team of medical professionals involved in the investigation, diagnosis, and management of patients with gastrointestinal cancer. Written and edited by leading international experts in the field it sets the standard in clinical practice for dealing with esophageal, gastric, intestinal, colonic, hepatobiliary, pancreatic, and other GI tumors. The book is divided into twenty-five clinical chapters each addressing the specific cancers affecting the gastrointestinal tract. Each chapter is written by a team of authors, with each contributor specially chosen to represent a different role in the MDT. This multidisciplinary team approach reflects the current care of GI cancer patients and enables clinical decision making and patient management. All the chapters have been tried and tested in MDT meetings in leading cancer centers around the world. Gastrointestinal Oncology: A Critical Multidisciplinary Team Approach provides in-depth evidence-based knowledge and is well illustrated throughout with color photographs, line drawings, and diagrams. This authoritative and practical resource is an essential reference for the entire MDT including gastroenterologists, hepatologists, GI surgeons, medical oncologists, radiation therapists, interventional radiologists, pathologists, specialist nurses, and clinical scientists.

Gastrointestinal Oncology

Author : Charles D. Blanke
Publisher : Springer Science & Business Media
ISBN 13 : 3642133061
Total Pages : 461 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Gastrointestinal Oncology by : Charles D. Blanke

Download or read book Gastrointestinal Oncology written by Charles D. Blanke and published by Springer Science & Business Media. This book was released on 2010-11-30 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal Oncology is an evidence-based, practical reference intended to assist in the diagnosis and management of patients with gastrointestinal malignancies. It is designed to be as user friendly as possible and is distinguished by the extremely practical, concrete nature of the information presented and by the multidisciplinary approach adopted. In addition to disease-oriented chapters spanning sites from the esophagus to the anus, non-anatomic subjects such as modern imaging techniques are also addressed. Translational science is supplied where useful in the decision-making process. All of the authors are internationally recognized experts. This book is an ideal resource for oncologists, surgeons, gastroenterologists, and primary-care providers looking for the latest and best information on how to deal with a wide variety of gastrointestinal neoplasms.

Multimodal Therapy of Upper Gastrointestinal Malignancies

Author : Ulrich Ronellenfitsch
Publisher : MDPI
ISBN 13 : 3036509208
Total Pages : 272 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Multimodal Therapy of Upper Gastrointestinal Malignancies by : Ulrich Ronellenfitsch

Download or read book Multimodal Therapy of Upper Gastrointestinal Malignancies written by Ulrich Ronellenfitsch and published by MDPI. This book was released on 2021-08-30 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent decades have seen remarkable advances in the treatment of upper gastrointestinal malignancies, i.e., adenocarcinoma and squamous cell carcinoma as well as gastrointestinal stromal and other rare tumors of the esophagus and stomach. While, historically, surgical resection has been the sole treatment for these tumors, multimodal therapies have meanwhile proven their efficacy. At present, pre- and postoperative chemotherapy and radiotherapy, targeted drug therapy, and stage-specific surgical approaches are all indispensable cornerstones of an individualized treatment for upper gastrointestinal malignancies. With such multimodal treatment, better outcomes comprising improved quality of life and prolonged survival have been achieved for patients. However, for many tumor entities and stages, the ideal combination and sequence of treatments is still being evaluated in clinical trials. Moreover, the value of novel approaches such as immunotherapy or robotic surgery remains a matter of research. In this Special Issue of Cancers, up-to-date original research, short communications, and comprehensive review articles on all modalities playing a role in the treatment of upper gastrointestinal malignancies have been published.

Management of Gastric Cancer

Author : Paul H. Sugarbaker
Publisher : Springer Science & Business Media
ISBN 13 : 1461538823
Total Pages : 405 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Management of Gastric Cancer by : Paul H. Sugarbaker

Download or read book Management of Gastric Cancer written by Paul H. Sugarbaker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastric cancer has been one of the great malignant scourges affecting man kind for as long as medical records have been kept. Until operative resection pioneered by Bilroth and others became available, no effective treatment was feasible and death from cancer was virtually inevitable. Even with resection by total gastrectomy, the chances of tumor eradication remained small. Over recent years, however, the situation has been changing. Some changes have resulted from better understanding of the disease, early detec tion, and better management techniques with applied clinical research, but the reasons for other changes are poorly understood. For example, the incidence of gastric cancer is decreasing, especially in westernized societies, where it has fallen from one of the most common cancers to no longer being in the top five causes of cancer death. Still it remains the number one killer of adult males in Japan and Korea. Whether the reduced incidence in western societies is a result of dietary changes or methods of food preservation, or some other reason, is as yet uncertain. Improvements in outcome have been reported from mass screening and early detection; more refined techniques of establishing early diagnosis, tumor type, and tumor extent; more radical surgical resection; and resection at earlier stages of disease.

Radiation and the Gastrointestinal Tract

Author : Andre Dubois
Publisher : CRC Press
ISBN 13 : 9780849376672
Total Pages : 306 pages
Book Rating : 4.3/5 (766 download)

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Book Synopsis Radiation and the Gastrointestinal Tract by : Andre Dubois

Download or read book Radiation and the Gastrointestinal Tract written by Andre Dubois and published by CRC Press. This book was released on 1994-11-22 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book evolved from a two-day 1993 International Symposium on Radiation and the Gastrointestinal Tract held at the Uniformed Services University of the Health Sciences, Bethesda, Maryland. This area of investigation is particularly important because of growing medical needs and the documented occurrence of accidents involving overexposure of healthy subjects/patients. Some questions have been answered through cellular and animal research-results that lead to hypotheses that have been tested through clinical protocols. In an attempt to answer the unresolved questions, basic scientists and clinicians describe the data obtained to date, present in a critical manner the consensus that has been reached, and discuss what still remains to be investigated. The book is divided into five parts: Overview and Clinical Perspective, Emesis, Motility, Diarrhea, and Behavioral Correlates of Gastrointestinal Dysfunction. Each part consists of separate discussions on the pathophysiology, the methodology, and, when applicable, the clinical relevance of the observations. The book provides helpful information to both basic scientists involved in radiobiological research and to clinicians caring for patients exposed to radiation. It also serves as an introduction to the subject for young clinical investigators interested in the field and for scientists searching for correlates between their observations and disorders of the gastrointestinal tract.

Combined Modality Therapy of Gastrointestinal Tract Cancer

Author : Peter Schlag
Publisher : Springer Science & Business Media
ISBN 13 : 3642832938
Total Pages : 345 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Combined Modality Therapy of Gastrointestinal Tract Cancer by : Peter Schlag

Download or read book Combined Modality Therapy of Gastrointestinal Tract Cancer written by Peter Schlag and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern surgical oncology is characterized by multimodal therapy. In recent years numerous therapeutic approaches of pre-, peri-, intra-and postoperative treatment have been in vestigated with regard to their use in combination with surgi cal intervention. It now is time to analyze and to define the state of our knowledge. For tumors of the gastrointestinal tract there are several encouraging therapeutic approaches, such as preop erative chemotherapy in esophageal and perioperative chemotherapy in colon cancer. For some special tumors, like anal carcinoma, we have clearly defined combined therapies which even now must be viewed as standard treatment. It is also time to demonstrate the results of several clini cal studies that have been conducted within the last few years that combined surgical efforts with pre- or postinter ventional chemotherapy or radiotherapy. It is necessary to evaluate whether these trials contribute to progress in onco logical therapy. The editors of this volume - surgeons at the university hospitals of Heidelberg and Zurich - must be given the mer it of achieving these goals. It was especially appropriate for the Department of Surgery in Heidelberg, in close coopera tion with the Comprehensive Cancer Center Heidelberg/ Mannheim, to prepare a review of our present knowledge of surgical oncology as it is in the tradition of attempting to combine different therapeutic approaches to cancer therapy.

Gastrointestinal Oncology

Author : James L. Abbruzzese
Publisher : Medicine
ISBN 13 : 0195133722
Total Pages : 938 pages
Book Rating : 4.1/5 (951 download)

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Book Synopsis Gastrointestinal Oncology by : James L. Abbruzzese

Download or read book Gastrointestinal Oncology written by James L. Abbruzzese and published by Medicine. This book was released on 2004 with total page 938 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 74 chapters, Gastrointestinal Oncology brings together a diverse group of specialists to provide the most authoritative, up-to-date and encyclopedic volume currently available on the subject. The first part of this text introduces a series of concepts and topics taht are important to gastrointestinal malignancies in general. These topics include epidemiologic principles, prevention, screening, familial GI cancers, developmental and molecular biology, pathobiology, general therapeutic principles, emerging therapies, and palliative care. The second part of the book covers each of the specific cancers affecting the human gastrointestinal tract. These chapters are introduced by state of the art discussions outlining our current understanding of the pathobiology and molecular biology relevant to each cancer. Subsequent sections describe the multidisciplinary management of specific clinical situations. By organizing the treatment-related chapters around clinical scenarios, the reader will readily find the information necessary to effectively manage the complex clinical situations encountered by patients with gastrointestinal malignancies.

Cancer of the Gastrointestinal Tract

Author : Davina Porock
Publisher : John Wiley & Sons
ISBN 13 : 0470031654
Total Pages : 200 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Cancer of the Gastrointestinal Tract by : Davina Porock

Download or read book Cancer of the Gastrointestinal Tract written by Davina Porock and published by John Wiley & Sons. This book was released on 2006-02-03 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is a primer on the care of the patient with cancer of the gastrointestinal tract, for nurses who may not have experience in this demanding speciality. The book begins with a comprehensive look at the issues and scope of the frequently used term "quality of life". Chapters two and three take an in-depth look at the impact of cancer on the individual and the family. Chapters four to six then introduce the principal aspects of cancer as a disease from both a medical and nursing perspective, beginning with cancers of the aerodigestive tract through to lower gastrointestinal cancers. Chapter seven covers the role of nutrition in the prevention of cancer and the nutritional management of patients with cancer. Chapters eight and nine provide a guide to the management of patients undergoing radiotherapy and chemotherapy in order to familiarize the gastroenterology nurse with what may lie ahead for the patient. The final chapter outlines the principles of symptom management and palliative care for integration into patient care throughout the course of cancer.

Principles and Practice of Gastrointestinal Oncology

Author : David Kelsen
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781776172
Total Pages : 786 pages
Book Rating : 4.7/5 (761 download)

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Book Synopsis Principles and Practice of Gastrointestinal Oncology by : David Kelsen

Download or read book Principles and Practice of Gastrointestinal Oncology written by David Kelsen and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly updated for its Second Edition, this text provides comprehensive, interdisciplinary coverage of gastrointestinal cancer, including molecular biology, diagnosis, medical, surgical, and radiation therapy, and palliative care. The initial section, Principles of Gastrointestinal Oncology, includes an expanded radiation oncology chapter, an extensively revised cancer genetics chapter, and a completely rewritten medical oncology chapter emphasizing new agents. Subsequent sections focus on esophageal, gastric, pancreatic, hepatocellular, biliary tree, and colorectal cancer. Coverage of each anatomic site includes epidemiology, screening, and prevention; molecular biology and genetics; pathology; anatomy and staging; and clinical management. The final section on uncommon cancers includes new chapters on neuroendocrine tumors and small bowel cancers. A companion Website provides instant access to the complete, fully searchable text.

Cancer of the Upper Gastrointestinal Tract

Author : Mitchell C. Posner
Publisher : PMPH-USA
ISBN 13 : 9781550091014
Total Pages : 422 pages
Book Rating : 4.0/5 (91 download)

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Book Synopsis Cancer of the Upper Gastrointestinal Tract by : Mitchell C. Posner

Download or read book Cancer of the Upper Gastrointestinal Tract written by Mitchell C. Posner and published by PMPH-USA. This book was released on 2002 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collectively, cancer of the esophagus, stomach and small intestine represent the second most common site and cause of death amongst the digestive system cancers. These disparate malignancies have one thing in common: consistently effective treatment remains elusive. This book is a comprehensive guide to diagnosis, management, and post-treatment care. Epidemiologic factors, molecular and biologic determinants, diagnostic/staging methods and treatment modalities are described for each organ site. The text is thoroughly supported by color illustrations, a key feature of the American Cancer Society Atlas of Clinical Oncology series. The expert contributors from medical, surgical and radiation oncology examine the advances in imaging, interventional gastroenterology, surgical technique, and combined modality therapy and discuss their impact in the management of this challenging group of cancers.

Rectal Cancer Treatment

Author : M.W. Büchler
Publisher : Springer Science & Business Media
ISBN 13 : 3540274499
Total Pages : 284 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Rectal Cancer Treatment by : M.W. Büchler

Download or read book Rectal Cancer Treatment written by M.W. Büchler and published by Springer Science & Business Media. This book was released on 2005-10-11 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer.