Chemoenzymatic Approach to the Synthesis of the Morphinan Skeleton Via a Claisen Rearrangement Approach

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ISBN 13 : 9780530000909
Total Pages : 198 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Chemoenzymatic Approach to the Synthesis of the Morphinan Skeleton Via a Claisen Rearrangement Approach by : Kofi Oppong

Download or read book Chemoenzymatic Approach to the Synthesis of the Morphinan Skeleton Via a Claisen Rearrangement Approach written by Kofi Oppong and published by . This book was released on 2018-12-06 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dissertation Discovery Company and University of Florida are dedicated to making scholarly works more discoverable and accessible throughout the world. This dissertation, "Chemoenzymatic Approach to the Synthesis of the Morphinan Skeleton via a Claisen Rearrangement Approach" by Kofi A. Oppong, was obtained from University of Florida and is being sold with permission from the author. A digital copy of this work may also be found in the university's institutional repository, IR@UF. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation.

Chemoenzymatic Approach to the Synthesis of the Morphinan Skeleton Via a Claisen Rearrangement Approach

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ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.:/5 (484 download)

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Book Synopsis Chemoenzymatic Approach to the Synthesis of the Morphinan Skeleton Via a Claisen Rearrangement Approach by : Kofi A. Oppong

Download or read book Chemoenzymatic Approach to the Synthesis of the Morphinan Skeleton Via a Claisen Rearrangement Approach written by Kofi A. Oppong and published by . This book was released on 2001 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Chemoenzymatic and Intramolecular Diels-Alder Approach Toward the Synthesis of Morphinan Skeletons

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Publisher :
ISBN 13 :
Total Pages : 356 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis A Chemoenzymatic and Intramolecular Diels-Alder Approach Toward the Synthesis of Morphinan Skeletons by : Bennett H. Novak

Download or read book A Chemoenzymatic and Intramolecular Diels-Alder Approach Toward the Synthesis of Morphinan Skeletons written by Bennett H. Novak and published by . This book was released on 2000 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:

American Doctoral Dissertations

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Publisher :
ISBN 13 :
Total Pages : 776 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis American Doctoral Dissertations by :

Download or read book American Doctoral Dissertations written by and published by . This book was released on 2001 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Dissertation Abstracts International

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ISBN 13 :
Total Pages : 896 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Dissertation Abstracts International by :

Download or read book Dissertation Abstracts International written by and published by . This book was released on 2002 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Organic Synthesis Highlights II

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Publisher : John Wiley & Sons
ISBN 13 : 3527620451
Total Pages : 420 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Organic Synthesis Highlights II by : Herbert Waldmann

Download or read book Organic Synthesis Highlights II written by Herbert Waldmann and published by John Wiley & Sons. This book was released on 2008-09-26 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Like its predecessor, Organic Synthesis Highlights II surveys recent accomplishments and current trends in synthetic organic chemistry. Part I describes new methods and reagents including asymmetric carbon-carbon bond formation with metallocenes and with enzymes, via temporary silicon connections, and by means of carbohydrate complexes. Part II describes landmarks in the synthesis of natural products and surveys synthetic strategies to different classes of natural products. The forty essays in this volume bear witness to the creativity and talent which have led to the recent advances in the field. Both advanced students and researchers active in the field will welcome this as a source of ideas and inspiration.

Alkaloid Synthesis

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Publisher : Springer Science & Business Media
ISBN 13 : 3642255280
Total Pages : 268 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Alkaloid Synthesis by : Hans-Joachim Knoelker

Download or read book Alkaloid Synthesis written by Hans-Joachim Knoelker and published by Springer Science & Business Media. This book was released on 2012-01-13 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lycopodium Alkaloids: Isolation and Asymmetric Synthesis, by Mariko Kitajima and Hiromitsu Takayama.- Synthesis of Morphine Alkaloids and Derivatives, by Uwe Rinner and Tomas Hudlicky.- Indole Prenylation in Alkaloid Synthesis, by Thomas Lindel, Nils Marsch and Santosh Kumar Adla.- Marine Pyrroloiminoquinone Alkaloids, by Yasuyuki Kita and Hiromichi Fujioka.- Synthetic Studies on Amaryllidaceae and Other Terrestrially Derived Alkaloids, by Martin G. Banwell, Nadia Yuqian Gao, Brett D. Schwartz and Lorenzo V. White.- Synthesis of Pyrrole and Carbazole Alkaloids, by Ingmar Bauer and Hans-Joachim Knölker.-

The Chemistry and Biology of Isoquinoline Alkaloids

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Publisher : Springer Science & Business Media
ISBN 13 : 3642701280
Total Pages : 315 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Chemistry and Biology of Isoquinoline Alkaloids by : J.D. Phillipson

Download or read book The Chemistry and Biology of Isoquinoline Alkaloids written by J.D. Phillipson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Isoquinolines form one of the largest groups of plant alkaloids and they in clude a number of valuable clinical agents such as codeine, morphine, eme tine and tubocurarine. Research into different aspects of isoquinolines con tinues in profusion, attracting the talents of botanists, chemists, bioche mists, analysts, pharmacists and pharmacologists. Many of these aspects are of an interdisciplinary nature, and in April 1984, The Phytochemical Society of Europe arranged a 3-day symposium on The Chemistry and Bi ology of Isoquinoline Alkaloids in order to provide a forum for scientists of differing disciplines who are united by a common interest in this one class of natural product. Each chapter in this volume is based on a lecture given at this symposium. Attempts have been made to make the aims and objectives, experimental findings and conclusions reached, intelligible to scientists of differing backgrounds. The introductory chapter, which is mainly based on a historical discus sion, stresses that plants containing isoquinolines have proved to be both a boon and a curse to mankind. The Opium Poppy, Papaver somniferum, produces the medicinally used alkaloids morphine, codeine, noscapine and papaverine whilst it also continues to provide drugs of abuse, particularly morphine and its readily prepared O,O-diacetyl derivative, heroin. Numer ous other alkaloids have been isolated from other members of the Papaver acea, and a knowledge of their presence and distribution within the various species has proved a useful adjunct to systematic botanical studies.

Modern Alkaloids

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Publisher : John Wiley & Sons
ISBN 13 : 3527621083
Total Pages : 689 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Modern Alkaloids by : Ernesto Fattorusso

Download or read book Modern Alkaloids written by Ernesto Fattorusso and published by John Wiley & Sons. This book was released on 2008-01-08 with total page 689 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents all important aspects of modern alkaloid chemistry, making it the only work of its kind to offer up-to-date and comprehensive coverage. While the first part concentrates on the structure and biology of bioactive alkaloids, the second one analyzes new trends in alkaloid isolation and structure elucidation, as well as in alkaloid synthesis and biosynthesis. A must for biochemists, organic, natural products, and medicinal chemists, as well as pharmacologists, pharmaceutists, and those working in the pharmaceutical industry.

From Biosynthesis to Total Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 1118751736
Total Pages : 585 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis From Biosynthesis to Total Synthesis by : Alexandros L. Zografos

Download or read book From Biosynthesis to Total Synthesis written by Alexandros L. Zografos and published by John Wiley & Sons. This book was released on 2016-04-18 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on biosynthesis, this book provides readers with approaches and methodologies for modern organic synthesis. By discussing major biosynthetic pathways and their chemical reactions, transformations, and natural products applications; it links biosynthetic mechanisms and more efficient total synthesis. • Describes four major biosynthetic pathways (acetate, mevalonate, shikimic acid, and mixed pathways and alkaloids) and their related mechanisms • Covers reactions, tactics, and strategies for chemical transformations, linking biosynthetic processes and total synthesis • Includes strategies for optimal synthetic plans and introduces a modern molecular approach to natural product synthesis and applications • Acts as a key reference for industry and academic readers looking to advance knowledge in classical total synthesis, organic synthesis, and future directions in the field

Heterocycles in Natural Product Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 3527634894
Total Pages : 648 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Heterocycles in Natural Product Synthesis by : Krishna C. Majumdar

Download or read book Heterocycles in Natural Product Synthesis written by Krishna C. Majumdar and published by John Wiley & Sons. This book was released on 2011-06-15 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filling a gap on the market, this handbook and ready reference is unique in its discussion of the usefulness of various heterocyclic systems in the synthesis of natural products. Clearly structured for easy access to the information, each chapter is devoted to a certain class of heterocycle, providing a tabular presentation of the natural products to be covered containing the particular heterocyclic ring system along with their biological profile, occurrence and most important physical properties, backed by the appropriate references. In addition, the application of the heterocyclic system to the synthesis of natural products ic covered in detail. Of great interest to organic, natural products, medicinal and biochemists, as well as those working in the pharmaceutical and agrochemical industry.

Strategies and Tactics in Organic Synthesis

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Publisher : Academic Press
ISBN 13 : 9780124502840
Total Pages : 522 pages
Book Rating : 4.5/5 (28 download)

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Book Synopsis Strategies and Tactics in Organic Synthesis by : Michael Harmata

Download or read book Strategies and Tactics in Organic Synthesis written by Michael Harmata and published by Academic Press. This book was released on 2004-11-03 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title provides a forum for investigators to discuss their approach to the science and art of organic synthesis in a unique way. There are stories that vividly demonstrate the power of the human endeavour known as organic synthesis and the creativity and tenacity of its practitioners.

Chemistry of Opioids

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Publisher : Springer
ISBN 13 : 3642181074
Total Pages : 321 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Chemistry of Opioids by : Hiroshi Nagase

Download or read book Chemistry of Opioids written by Hiroshi Nagase and published by Springer. This book was released on 2011-01-21 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Advances in the Synthesis of Morphine and Related Alkaloids; by N. Chida * Opioids in Preclinical and Clinical Trials; by H. Nagase and H. Fujii * Synthesis of 14-Alkoxymorphinan Derivatives and Their Pharmacological Actions; by H. Schmidhammer and M. Spetea * 14-Amino-4,5-Epoxymorphinan Derivatives and Their Pharmacological Actions; by J. W. Lewis and S. M. Husbands * Nonpeptidic Delta (δ) Opioid Agonists and Antagonists of the Diarylmethylpiperazine Class: What Have We Learned?; by S. N. Calderon * Synthesis of Neoclerodane Diterpenes and Their Pharmacological Effects; by K. M. Lovell, K. M. Prevatt-Smith, A. Lozama and T. E. Prisinzano * Synthesis of Novel Basic Skeletons Derived from Naltrexone; by H. Nagase and H. Fujii * Twin and Triplet Drugs in Opioid Research; by H. Fujii * 3D-Pharmacophore Identification for κ-Opioid Agonists Using Ligand-Based Drug-Design Techniques; by N. Yamaotsu and S. Hirono

Opium Poppy

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Publisher : CRC Press
ISBN 13 : 9781560249238
Total Pages : 356 pages
Book Rating : 4.2/5 (492 download)

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Book Synopsis Opium Poppy by : L. Kapoor

Download or read book Opium Poppy written by L. Kapoor and published by CRC Press. This book was released on 1995-08-08 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is an in-depth examination of the opium poppy--the first medicinal plant known to mankind. In Opium Poppy: Botany, Chemistry, and Pharmacology, author L. D. Kapoor provides readers with a comprehensive resource on poppy production from seed to alkaloid. He explores the opium poppy?s origin, distribution, chemistry, and uses and abuses from ancient civilizations through the present day. He covers plant and seed production and crop improvement and explores in detail the chemical and pharmaceutical by-products of the opium poppy. The book begins with a historical overview of the origin and use of opium poppy in ancient civilizations such as Greece, Egypt, and Mesopotamia. Chapters that follow contain detailed information on: botanical studies cytogenics and plant breeding agronomy, including insect and pest control measures physiological and anatomical studies chemical and pharmacological aspects of opium alkaloids biosynthesis and physiology of opium alkaloids the occurrence and role of alkaloids in plants the evaluation of analgesic actions of morphine in various pain models in experimental animals Opium Poppy: Botany, Chemistry, and Pharmacology is a useful reference for professionals and students of pharmacy, botany, chemistry, medicine, and pharmacology who need a better overall understanding of this ancient plant and its (potential) modern usage.

The Way of Synthesis

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Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 1032 pages
Book Rating : 4.X/5 (3 download)

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Book Synopsis The Way of Synthesis by : Tomas Hudlicky

Download or read book The Way of Synthesis written by Tomas Hudlicky and published by Wiley-VCH. This book was released on 2007-09-04 with total page 1032 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-colored textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of the most important total synthesis of the last 50 years with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, regardless of the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives and, what makes this textbook extraordinairy, with personal recollections of the chemists, who synthesized these fascinating compounds. With its attractive layout highlighting key parts and tactics using a second color, this is a useful tool for organic chemists, lecturers and students in chemistry, as well as those working in the chemical industry. "I think, as will many organic chemists, that the Hudlicky book will be the Bible of synthetic organic chemistry, the past, the present and the future. A hallmark publication." (Victor Snieckus)

Radicals in Synthesis III

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Publisher : Springer Science & Business Media
ISBN 13 : 3642281230
Total Pages : 465 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Radicals in Synthesis III by : Markus Heinrich

Download or read book Radicals in Synthesis III written by Markus Heinrich and published by Springer Science & Business Media. This book was released on 2012-02-21 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Boron-Doped Diamond Electrodes for Electroorganic Chemistry, by Siegfried R. Waldvogel, Stamo Mentizi und Axel Kirste.- Modern Developments in Aryl Radical Chemistry, by Gerald Pratsch und Markus R. Heinrich.- Radical Additions to Chiral Hydrazones: Stereoselectivity and Functional Group Compatibility, by Gregory K. Friestad.- Hydrogen Atom Donors: Recent Developments, by Andreas Gansäuer, Lei Shi, Matthias Otte, Inga Huth, Antonio Rosales, Iris Sancho-Sanz, Natalia M. Padial und J. Enrique Oltra.- Radicals in Transition Metal Catalyzed Reactions? Transition Metal Catalyzed Radical Reactions? - A Fruitful Interplay Anyway Part 1. Radical Catalysis by Group 4 to Group 7 Elements, by Ullrich Jahn.- Radicals in Transition Metal Catalyzed Reactions? Transition Metal Catalyzed Radical Reactions? - A Fruitful Interplay Anyway Part 2. Radical Catalysis by Group 8 and 9 Elements, by Ullrich Jahn.- Radicals in Transition Metal Catalyzed Reactions? Transition Metal Catalyzed Radical Reactions?: A Fruitful Interplay Anyway Part 3: Catalysis by Group 10 and 11 Elements and Bimetallic Catalysis, by Ullrich Jahn.-

Asymmetric Dearomatization Reactions

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Publisher : John Wiley & Sons
ISBN 13 : 3527338519
Total Pages : 422 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Asymmetric Dearomatization Reactions by : Shu-Li You

Download or read book Asymmetric Dearomatization Reactions written by Shu-Li You and published by John Wiley & Sons. This book was released on 2016-09-13 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive account of the rapidly growing field of asymmetric dearomatization reactions with a focus on catalytic methods. It introduces the concept of dearomatization and describes recent progress in asymmetric reaction procedures with different catalyst systems, such as organocatalysts, transition metal catalysts, and enzymes. Chapters on dearomatizations of electron-deficient aromatic rings, dearomatization reactions via transition metal-catalyzed cross-couplings as well as dearomatization strategies in the synthesis of complex natural products are also included. Written by pioneers in the field, this is a highly valuable source of information not only for professional synthetic chemists in academia and industry but also for all those are interested in asymmetric methodologies and organic synthesis in general.