Chemistry And Pharmacology

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Medicinal Chemistry and Pharmacology

Author : Avianna Stokes
Publisher :
ISBN 13 : 9781632415356
Total Pages : 222 pages
Book Rating : 4.4/5 (153 download)

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Book Synopsis Medicinal Chemistry and Pharmacology by : Avianna Stokes

Download or read book Medicinal Chemistry and Pharmacology written by Avianna Stokes and published by . This book was released on 2019-06-25 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry and pharmacology are closely associated fields. They are concerned with the design and synthesis of drugs for the pharmaceutical industry. These drugs are generally organic compounds and can be divided into classes of biologics and small organic compounds. Medicinal chemistry is focused on the production of small organic molecules such as atorvastatin, fluticasone, clopidogrel, etc. The principles of synthetic organic chemistry, computational chemistry, enzymology, structural biology and chemical biology are integrated in medicinal chemistry. The study of drugs and their effects on the living body are explored in pharmacology. It involves the research, discovery and characterization of the chemicals that exhibit a biological effect. All therapies that are designed to target diseases, defects and pathogens and also advance preventive care, diagnostics and personalized medicine are a result of tremendous research in pharmacology. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the fields of medicinal chemistry and pharmacology. The various advancements in these fields are glanced at and their applications as well as ramifications are looked at in detail. This book is a vital tool for all researching and studying pharmaceutical science and medicinal chemistry.

Chemistry and Pharmacology of Anticancer Drugs

Author : David E. Thurston
Publisher : CRC Press
ISBN 13 : 1420008900
Total Pages : 312 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Chemistry and Pharmacology of Anticancer Drugs by : David E. Thurston

Download or read book Chemistry and Pharmacology of Anticancer Drugs written by David E. Thurston and published by CRC Press. This book was released on 2006-11-22 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: While drug therapies developed in the last 50 years have markedly improved the management of some types of cancers, treatment outcomes, and drug side-effects for the most common types remain unacceptable. However, recent technological advances are leading to improved therapies based on targeting distinct biological pathways in cancer cells.

Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide

Author : Philip K. Moore
Publisher : Springer
ISBN 13 : 3319181440
Total Pages : 384 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide by : Philip K. Moore

Download or read book Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide written by Philip K. Moore and published by Springer. This book was released on 2015-07-10 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book puts hydrogen sulfide in context with other gaseous mediators such as nitric oxide and carbon monoxide, reviews the available mechanisms for its biosynthesis and describes its physiological and pathophysiological roles in a wide variety of disease states. Hydrogen sulfide has recently been discovered to be a naturally occurring gaseous mediator in the body. Over a relatively short period of time this evanescent gas has been revealed to play key roles in a range of physiological processes including control of blood vessel caliber and hence blood pressure and in the regulation of nerve function both in the brain and the periphery. Disorders concerning the biosynthesis or activity of hydrogen sulfide may also predispose the body to disease states such as inflammation, cardiovascular and neurological disorders. Interest in this novel gas has been high in recent years and many research groups worldwide have described its individual biological effects. Moreover, medicinal chemists are beginning to synthesize novel organic molecules that release this gas at defined rates with a view to exploiting these new compounds for therapeutic benefit.

The Organic Chemistry of Drug Design and Drug Action

Author : Richard B. Silverman
Publisher : Elsevier
ISBN 13 : 0080513379
Total Pages : 650 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Organic Chemistry of Drug Design and Drug Action by : Richard B. Silverman

Download or read book The Organic Chemistry of Drug Design and Drug Action written by Richard B. Silverman and published by Elsevier. This book was released on 2012-12-02 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

Chemistry and Pharmacology of Anticancer Drugs

Author : David E. Thurston
Publisher : CRC Press
ISBN 13 : 1439853274
Total Pages : 619 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Chemistry and Pharmacology of Anticancer Drugs by : David E. Thurston

Download or read book Chemistry and Pharmacology of Anticancer Drugs written by David E. Thurston and published by CRC Press. This book was released on 2021-03-17 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: While drug therapies developed in the last 80 years have markedly improved treatment outcomes and the management of some types of cancers, the lack of effectiveness and side effects associated with the most common treatment types remain unacceptable. However, recent technological advances are leading to improved therapies based on targeting distinct biological pathways in cancer cells. Chemistry and Pharmacology of Anticancer Drugs is a comprehensive survey of all families of anticancer agents and therapeutic approaches currently in use or in advanced stages of clinical trials, including biological-based therapies. The book is unique in providing molecular structures for all anticancer agents, discussing them in terms of history of development, chemistry, mechanism of action, structure–function relationships, and pharmacology. It also provides relevant information on side effects, dosing, and formulation. The authors, renowned scientists in cancer research and drug discovery, also provide up-to-date information on the drug discovery process, including discussions of new research tools, tumor-targeting strategies, and fundamental concepts in the relatively new areas of precision medicine and chemoprevention. Chemistry and Pharmacology of Anticancer Drugs is an indispensable resource for cancer researchers, medicinal chemists and other biomedical scientists involved in the development of new anticancer therapies. Its breadth of coverage, clear explanations, and illustrations also make it suitable for undergraduate and postgraduate courses in medicine, pharmacy, nursing, dentistry, nutrition, the biomedical sciences, and related disciplines. Key Features: Summarizes the fundamental causes of cancer, modes of treatment, and strategies for cancer drug discovery Brings together a broad spectrum of information relating to the chemistry and pharmacology of all families of anticancer agents and therapies Includes up-to-date information on cutting-edge aspects of cancer treatments such as biomarkers, pharmacogenetics, and pharmacogenomics Features new chapters on the "Evolution of Anticancer Therapies", "Antibody-Based Therapies", and "Cancer Chemoprevention"

Chemistry for Pharmacy Students

Author : Professor Satyajit D. Sarker
Publisher : John Wiley & Sons
ISBN 13 : 1118687531
Total Pages : 397 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Chemistry for Pharmacy Students by : Professor Satyajit D. Sarker

Download or read book Chemistry for Pharmacy Students written by Professor Satyajit D. Sarker and published by John Wiley & Sons. This book was released on 2013-05-28 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book has succeeded in covering the basic chemistry essentials required by the pharmaceutical science student... the undergraduate reader, be they chemist, biologist or pharmacist will find this an interesting and valuable read." –Journal of Chemical Biology, May 2009 Chemistry for Pharmacy Students is a student-friendly introduction to the key areas of chemistry required by all pharmacy and pharmaceutical science students. The book provides a comprehensive overview of the various areas of general, organic and natural products chemistry (in relation to drug molecules). Clearly structured to enhance student understanding, the book is divided into six clear sections. The book opens with an overview of general aspects of chemistry and their importance to modern life, with particular emphasis on medicinal applications. The text then moves on to a discussion of the concepts of atomic structure and bonding and the fundamentals of stereochemistry and their significance to pharmacy- in relation to drug action and toxicity. Various aspects of aliphatic, aromatic and heterocyclic chemistry and their pharmaceutical importance are then covered with final chapters looking at organic reactions and their applications to drug discovery and development and natural products chemistry. accessible introduction to the key areas of chemistry required for all pharmacy degree courses student-friendly and written at a level suitable for non-chemistry students includes learning objectives at the beginning of each chapter focuses on the physical properties and actions of drug molecules

Phytocannabinoids

Author : A. Douglas Kinghorn
Publisher : Springer
ISBN 13 : 3319455419
Total Pages : 137 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Phytocannabinoids by : A. Douglas Kinghorn

Download or read book Phytocannabinoids written by A. Douglas Kinghorn and published by Springer. This book was released on 2017-01-24 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents the current state of the art on phytocannnabinoid chemistry and pharmacology and will be of much use to those wishing to understand the current landscape of the exciting and intriguing phytocannabinoid science. The focus is on natural product cannabinoids which have been demonstrated to act at specific receptor targets in the CNS.

The Chemistry of Mind-altering Drugs

Author : Daniel M. Perrine
Publisher :
ISBN 13 :
Total Pages : 504 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis The Chemistry of Mind-altering Drugs by : Daniel M. Perrine

Download or read book The Chemistry of Mind-altering Drugs written by Daniel M. Perrine and published by . This book was released on 1996 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fascinating book presents a scientifically objective, and thoroughly documented exposition of the pharmacological and psychological effects of nearly every known substance that affects human consciousness, from alcohol to Zopiclone. It also features first-hand accounts and descriptions of the social, cultural, and religious milieus in which many psychotropic plants are used, and discusses historical allusions to many literary and scientific figures who used or wrote of mind-altering drugs, including Freud, Dickens, Yeats, and Huxley. Intended for a wide audience of general readers seeking unbiased information, the book gives an accessible explanation of drug-receptor interaction and organic chemical structures, as well as descriptions of the discovery, isolation, and syntheses of the chemical substances responsible for drug activity. Written by an experienced chemist, the book nevertheless keeps technical information to a minimum.

Solubility in Pharmaceutical Chemistry

Author : Christoph Saal
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110558882
Total Pages : 418 pages
Book Rating : 4.1/5 (15 download)

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Book Synopsis Solubility in Pharmaceutical Chemistry by : Christoph Saal

Download or read book Solubility in Pharmaceutical Chemistry written by Christoph Saal and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-01-20 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the physicochemical fundamentals and biomedical principles of drug solubility. Methods to study and predict solubility in silico and in vitro are described and the role of solubility in a medicinal chemistry and pharmaceutical industry context are discussed. Approaches to modify and control solubility of a drug during the manufacturing process and of the pharmaceutical product are essential practical aspects of this book.

Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds

Author : Goutam Brahmachari
Publisher : CRC Press
ISBN 13 : 9781032099132
Total Pages : 584 pages
Book Rating : 4.0/5 (991 download)

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Book Synopsis Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds by : Goutam Brahmachari

Download or read book Chemistry and Pharmacology of Naturally Occurring Bioactive Compounds written by Goutam Brahmachari and published by CRC Press. This book was released on 2021-06-30 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written for phytochemists, synthetic chemists, combinatorial chemists, as well as other practitioners and students in related fields, this volume presents cutting-edge research in the chemistry of bioactive natural products and helps the reader understand how natural product research continues to make significant contributions in the discovery a

Natural Products

Author : Goutam Brahmachari
Publisher : Alpha Science International, Limited
ISBN 13 :
Total Pages : 848 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Natural Products by : Goutam Brahmachari

Download or read book Natural Products written by Goutam Brahmachari and published by Alpha Science International, Limited. This book was released on 2009 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Products provides an insight into significant developments in some of the promising areas of natural products chemistry. Natural products are of great interest and promise in the present day research directed towards drug design and discovery. This book brings together leading scientists of the world, an overview of current discoveries and trends in this remarkable field. The topics, ranging from natural products chemistry and phytochemistry in their most basic form to molecular biology, pharmacology and in silico drug design, summarize years of extensive research in each area, and provide insight in the new themes of natural products research. The book serves as a valuable resource for researchers in their own fields to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations; it also motivates young scientists to the dynamic field of bioactive natural products research.

Radiopharmaceuticals

Author : AdrainD. Nunn
Publisher : Routledge
ISBN 13 : 1351419900
Total Pages : 460 pages
Book Rating : 4.3/5 (514 download)

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Book Synopsis Radiopharmaceuticals by : AdrainD. Nunn

Download or read book Radiopharmaceuticals written by AdrainD. Nunn and published by Routledge. This book was released on 2018-04-27 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely resource compares single-photon emission tomography (SPECT), used mainly withTechnetium and iodine for routine clinical examinations, and positron emission tomography(PET) , employing short-lived radionuclides of carbon, oxygen, nitrogen, and fluorine in researchinvestigations.Presenting the logic behind why one approach is better than another in various circumstances,Radio pharmaceuticals details the use of radiolabelled substrates in measuring the effect of diseaseand drugs on regional metabolism and receptor concentration/occupancy .. . discusses factorsaffecting the selective retention of small metal complexes by various tissues .. . analyzes the interactionof small exogenous metal complexes with enzymes in vivo and the critical role of stereochemistry. . . explores the use of radio labelled compounds in the study of neuroactive compounds,neurotransmitters, enzyme inhibitors, and substrates in vivo .. . covers the design and pharmacologyof radiolabelled drugs as probes of site of action , selectivity and specificity, and pharmacokineticsin vivo .. . and more.Extensively referenced with over l 050 bibliographic citations, Radiopharmaceuticals is a state-ofthe-art guide for pharmacists; organic, medicinal , and radiopharmaceutical chemists; pharmacokineticists;nuclear medicine physicians and technologists; neurochemists; and governmentregulatory personnel .

Kratom and Other Mitragynines

Author : Robert B. Raffa
Publisher : CRC Press
ISBN 13 : 1482225190
Total Pages : 356 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Kratom and Other Mitragynines by : Robert B. Raffa

Download or read book Kratom and Other Mitragynines written by Robert B. Raffa and published by CRC Press. This book was released on 2014-10-29 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Opioids such as morphine, codeine, and oxycodone are extracts or analogs isolated from a single source: the opium poppy. For a long time, it was believed to be nature's only source of opioids. But it now appears that biological diversity has evolved an alternative source of opioid compounds-those derived from the plant Mitragyna speciosa. This plan

Experiments in Pharmaceutical Chemistry, Second Edition

Author : Charles Dickson
Publisher : CRC Press
ISBN 13 : 1482225085
Total Pages : 162 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Experiments in Pharmaceutical Chemistry, Second Edition by : Charles Dickson

Download or read book Experiments in Pharmaceutical Chemistry, Second Edition written by Charles Dickson and published by CRC Press. This book was released on 2014-02-21 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by an author with more than 40 years of teaching experience in the field, Experiments in Pharmaceutical Chemistry, Second Edition responds to a critical classroom need for material on directed laboratory investigations in biological and pharmaceutical chemistry. This new edition supplies 75 experiments, expanding the range of topics to 22 major areas of pharmaceutical chemistry. These include biochemical groups, botanical classes important to pharmacy, and major drug classifications: Carbohydrates Lipids Proteins Enzymes Inorganics Vitamins Steroids Plant Acids Flavonoids Alkaloids Tannins Resins Glycosides Gums Balsams Volatile Oils Analgesics Anesthetics Sulfa Drugs (Sulfonamides) Psychotropic Drugs Antibiotics Nucleic Acids Sections contain introductions to basic concepts underlying the fields addressed and a specific bibliography relating to each field. Each experiment provides detailed instructions in a user-friendly format, and can be carried out, in most cases, without the need for expensive instrumentation. This comprehensive laboratory manual offers much-needed instructional material for teaching laboratory classes in pharmaceutical chemistry. The breadth of subject matter covered provides a variety of choices for structuring a laboratory course.

Natural Product Chemistry for Drug Discovery

Author : Antony D. Buss
Publisher : Royal Society of Chemistry
ISBN 13 : 0854041931
Total Pages : 459 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis Natural Product Chemistry for Drug Discovery by : Antony D. Buss

Download or read book Natural Product Chemistry for Drug Discovery written by Antony D. Buss and published by Royal Society of Chemistry. This book was released on 2010 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive summary of where natural product chemistry is today in drug discovery. It covers emerging technologies and case studies and is a source of up-to-date information on the topical subject of natural products.

Organic Chemistry of Drug Degradation

Author : Min Li
Publisher : Royal Society of Chemistry
ISBN 13 : 1849734216
Total Pages : 311 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Organic Chemistry of Drug Degradation by : Min Li

Download or read book Organic Chemistry of Drug Degradation written by Min Li and published by Royal Society of Chemistry. This book was released on 2012 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines drug degradation pathways with an emphasis on the underlying chemical mechanisms.

Chiral Drugs

Author : Guo-Qiang Lin
Publisher : John Wiley & Sons
ISBN 13 : 1118075633
Total Pages : 469 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Chiral Drugs by : Guo-Qiang Lin

Download or read book Chiral Drugs written by Guo-Qiang Lin and published by John Wiley & Sons. This book was released on 2011-08-08 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrated view of chiral drugs from concept and synthesisto pharmaceutical properties Chirality greatly influences a drug's biological and pharmacological properties. In an effort to achieve more predictable results from chiral drugs, the Food and Drug Administration now requires that these medicines be as pure as possible, which places great demands on drug synthesis, purification, analysis, and testing. To assist researchers in acquiring the essential knowledge to meet these rigid guidelines, Chiral Drugs focuses on three vital chiral technologies asymmetric synthesis, biocatalytic process, and chiral resolution to offer details on the basic concepts, key developments, and recent trends in chiral drug discovery, along with: The history of chiral drugs development and industrial applications of chiral technologies A section listing twenty-five approved or advanced-trial chiral drugs that lists each drug name, chemical name and properties, a representative synthetic pathway, pharmacological characterizations, and references An interdisciplinary approach combining synthetic organic chemistry, medicinal chemistry, and pharmacology Nearly two-thirds of the drugs on today's market are chiral drugs. Reducing and eliminating their negative characteristics is an ongoing and serious challenge for the pharmaceutical industry. With its well-balanced approach to covering each important aspect of chirality, Chiral Drugs champions important strategies for tipping the medical scale in a positive direction for the production of more effective and safer drugs.