From Neurons to Neighborhoods

Download From Neurons to Neighborhoods PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309069882
Total Pages : 610 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!


Book Synopsis From Neurons to Neighborhoods by : National Research Council

Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Discovering the Brain

Download Discovering the Brain PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309045290
Total Pages : 195 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!


Book Synopsis Discovering the Brain by : National Academy of Sciences

Download or read book Discovering the Brain written by National Academy of Sciences and published by National Academies Press. This book was released on 1992-01-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Chemistry and Brain Development

Download Chemistry and Brain Development PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1468472364
Total Pages : 447 pages
Book Rating : 4.4/5 (684 download)

DOWNLOAD NOW!


Book Synopsis Chemistry and Brain Development by : Rodolfo Paoletti

Download or read book Chemistry and Brain Development written by Rodolfo Paoletti and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: J. Folch-Pi Director of Scientific Research, McLean Hospital, Belmont, Mass., U.S.A. The development of the central nervous system is possibly the most significant aspect of the growth of a mammal from embryo to adulthood. The central nervous system is obviously the main repository not only of the species' inherited functional characteristics but also of the process of individuation. Whatever "engrams" constitute the basis of individual characteristics are laid down mainly in the central nervous system, and especially the brain, during its growth. The chemical aspect of this process IS clearly of great importance and the significance of its study should be self evident. Nevertheless, it is only one aspect of a parel lei series of morphological, physiological, biochemical and psychological events which take place as an integrated process, the final result of which is the transformation of the post-embryonic nervous system into the functioning adult system. It is imperative, therefore, that any study or description of the chemical events during the development of the CNS should be undertaken in ful I awareness of the concomitant morphological, physiological and psychological events. It is only against this multidiscipl inary informational framework that the chemical events during 2 J. FOLCH-PI development can be correctly interpreted and acquire their ful I significance. With this in mind, the introduction to this volume may best serve its purpose by describing briefly the morphological and physiological events that accompany the chemical aspect of development.

How People Learn

Download How People Learn PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309131979
Total Pages : 386 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis How People Learn by : National Research Council

Download or read book How People Learn written by National Research Council and published by National Academies Press. This book was released on 2000-08-11 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: First released in the Spring of 1999, How People Learn has been expanded to show how the theories and insights from the original book can translate into actions and practice, now making a real connection between classroom activities and learning behavior. This edition includes far-reaching suggestions for research that could increase the impact that classroom teaching has on actual learning. Like the original edition, this book offers exciting new research about the mind and the brain that provides answers to a number of compelling questions. When do infants begin to learn? How do experts learn and how is this different from non-experts? What can teachers and schools do-with curricula, classroom settings, and teaching methodsâ€"to help children learn most effectively? New evidence from many branches of science has significantly added to our understanding of what it means to know, from the neural processes that occur during learning to the influence of culture on what people see and absorb. How People Learn examines these findings and their implications for what we teach, how we teach it, and how we assess what our children learn. The book uses exemplary teaching to illustrate how approaches based on what we now know result in in-depth learning. This new knowledge calls into question concepts and practices firmly entrenched in our current education system. Topics include: How learning actually changes the physical structure of the brain. How existing knowledge affects what people notice and how they learn. What the thought processes of experts tell us about how to teach. The amazing learning potential of infants. The relationship of classroom learning and everyday settings of community and workplace. Learning needs and opportunities for teachers. A realistic look at the role of technology in education.

Toxicological Effects of Methylmercury

Download Toxicological Effects of Methylmercury PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309171717
Total Pages : 364 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Toxicological Effects of Methylmercury by : National Research Council

Download or read book Toxicological Effects of Methylmercury written by National Research Council and published by National Academies Press. This book was released on 2000-09-27 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mercury is widespread in our environment. Methylmercury, one organic form of mercury, can accumulate up the aquatic food chain and lead to high concentrations in predatory fish. When consumed by humans, contaminated fish represent a public health risk. Combustion processes, especially coal-fired power plants, are major sources of mercury contamination in the environment. The U.S. Environmental Protection Agency (EPA) is considering regulating mercury emissions from those plants. Toxicological Effects of Methylmercury reviews the health effects of methylmercury and discusses the estimation of mercury exposure from measured biomarkers, how differences between individuals affect mercury toxicity, and appropriate statistical methods for analysis of the data and thoroughly compares the epidemiological studies available on methylmercury. Included are discussions of current mercury levels on public health and a delineation of the scientific aspects and policy decisions involved in the regulation of mercury. This report is a valuable resource for individuals interested in the public health effects and regulation of mercury. The report also provides an excellent example of the implications of decisions in the risk assessment process for a larger audience.

How People Learn II

Download How People Learn II PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309459672
Total Pages : 347 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!


Book Synopsis How People Learn II by : National Academies of Sciences, Engineering, and Medicine

Download or read book How People Learn II written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-09-27 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are many reasons to be curious about the way people learn, and the past several decades have seen an explosion of research that has important implications for individual learning, schooling, workforce training, and policy. In 2000, How People Learn: Brain, Mind, Experience, and School: Expanded Edition was published and its influence has been wide and deep. The report summarized insights on the nature of learning in school-aged children; described principles for the design of effective learning environments; and provided examples of how that could be implemented in the classroom. Since then, researchers have continued to investigate the nature of learning and have generated new findings related to the neurological processes involved in learning, individual and cultural variability related to learning, and educational technologies. In addition to expanding scientific understanding of the mechanisms of learning and how the brain adapts throughout the lifespan, there have been important discoveries about influences on learning, particularly sociocultural factors and the structure of learning environments. How People Learn II: Learners, Contexts, and Cultures provides a much-needed update incorporating insights gained from this research over the past decade. The book expands on the foundation laid out in the 2000 report and takes an in-depth look at the constellation of influences that affect individual learning. How People Learn II will become an indispensable resource to understand learning throughout the lifespan for educators of students and adults.

The Teenage Brain

Download The Teenage Brain PDF Online Free

Author :
Publisher : Harper Collins
ISBN 13 : 0062067869
Total Pages : 270 pages
Book Rating : 4.0/5 (62 download)

DOWNLOAD NOW!


Book Synopsis The Teenage Brain by : Frances E. Jensen

Download or read book The Teenage Brain written by Frances E. Jensen and published by Harper Collins. This book was released on 2015-01-06 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: A New York Times Bestseller Renowned neurologist Dr. Frances E. Jensen offers a revolutionary look at the brains of teenagers, dispelling myths and offering practical advice for teens, parents and teachers. Dr. Frances E. Jensen is chair of the department of neurology in the Perelman School of Medicine at the University of Pennsylvania. As a mother, teacher, researcher, clinician, and frequent lecturer to parents and teens, she is in a unique position to explain to readers the workings of the teen brain. In The Teenage Brain, Dr. Jensen brings to readers the astonishing findings that previously remained buried in academic journals. The root myth scientists believed for years was that the adolescent brain was essentially an adult one, only with fewer miles on it. Over the last decade, however, the scientific community has learned that the teen years encompass vitally important stages of brain development. Samples of some of the most recent findings include: Teens are better learners than adults because their brain cells more readily "build" memories. But this heightened adaptability can be hijacked by addiction, and the adolescent brain can become addicted more strongly and for a longer duration than the adult brain. Studies show that girls' brains are a full two years more mature than boys' brains in the mid-teens, possibly explaining differences seen in the classroom and in social behavior. Adolescents may not be as resilient to the effects of drugs as we thought. Recent experimental and human studies show that the occasional use of marijuana, for instance, can cause lingering memory problems even days after smoking, and that long-term use of pot impacts later adulthood IQ. Multi-tasking causes divided attention and has been shown to reduce learning ability in the teenage brain. Multi-tasking also has some addictive qualities, which may result in habitual short attention in teenagers. Emotionally stressful situations may impact the adolescent more than it would affect the adult: stress can have permanent effects on mental health and can to lead to higher risk of developing neuropsychiatric disorders such as depression. Dr. Jensen gathers what we’ve discovered about adolescent brain function, wiring, and capacity and explains the science in the contexts of everyday learning and multitasking, stress and memory, sleep, addiction, and decision-making. In this groundbreaking yet accessible book, these findings also yield practical suggestions that will help adults and teenagers negotiate the mysterious world of adolescent development.

The Role of Protein and Amino Acids in Sustaining and Enhancing Performance

Download The Role of Protein and Amino Acids in Sustaining and Enhancing Performance PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309172810
Total Pages : 448 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis The Role of Protein and Amino Acids in Sustaining and Enhancing Performance by : Institute of Medicine

Download or read book The Role of Protein and Amino Acids in Sustaining and Enhancing Performance written by Institute of Medicine and published by National Academies Press. This book was released on 1999-09-15 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a commonly held belief that athletes, particularly body builders, have greater requirements for dietary protein than sedentary individuals. However, the evidence in support of this contention is controversial. This book is the latest in a series of publications designed to inform both civilian and military scientists and personnel about issues related to nutrition and military service. Among the many other stressors they experience, soldiers face unique nutritional demands during combat. Of particular concern is the role that dietary protein might play in controlling muscle mass and strength, response to injury and infection, and cognitive performance. The first part of the book contains the committee's summary of the workshop, responses to the Army's questions, conclusions, and recommendations. The remainder of the book contains papers contributed by speakers at the workshop on such topics as, the effects of aging and hormones on regulation of muscle mass and function, alterations in protein metabolism due to the stress of injury or infection, the role of individual amino acids, the components of proteins, as neurotransmitters, hormones, and modulators of various physiological processes, and the efficacy and safety considerations associated with dietary supplements aimed at enhancing performance.

The Myth of the First Three Years

Download The Myth of the First Three Years PDF Online Free

Author :
Publisher : Simon and Schuster
ISBN 13 : 1439118744
Total Pages : 365 pages
Book Rating : 4.4/5 (391 download)

DOWNLOAD NOW!


Book Synopsis The Myth of the First Three Years by : John Bruer

Download or read book The Myth of the First Three Years written by John Bruer and published by Simon and Schuster. This book was released on 2010-05-11 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most parents today have accepted the message that the first three years of a baby's life determine whether or not the child will grow into a successful, thinking person. But is this powerful warning true? Do all the doors shut if baby's brain doesn't get just the right amount of stimulation during the first three years of life? Have discoveries from the new brain science really proved that parents are wholly responsible for their child's intellectual successes and failures alike? Are parents losing the "brain wars"? No, argues national expert John Bruer. In The Myth of the First Three Years he offers parents new hope by debunking our most popular beliefs about the all-or-nothing effects of early experience on a child's brain and development. Challenging the prevailing myth -- heralded by the national media, Head Start, and the White House -- that the most crucial brain development occurs between birth and age three, Bruer explains why relying on the zero to three standard threatens a child's mental and emotional well-being far more than missing a few sessions of toddler gymnastics. Too many parents, educators, and government funding agencies, he says, see these years as our main opportunity to shape a child's future. Bruer agrees that valid scientific studies do support the existence of critical periods in brain development, but he painstakingly shows that these same brain studies prove that learning and cognitive development occur throughout childhood and, indeed, one's entire life. Making hard science comprehensible for all readers, Bruer marshals the neurological and psychological evidence to show that children and adults have been hardwired for lifelong learning. Parents have been sold a bill of goods that is highly destructive because it overemphasizes infant and toddler nurturing to the detriment of long-term parental and educational responsibilities. The Myth of the First Three Years is a bold and controversial book because it urges parents and decision-makers alike to consider and debate for themselves the evidence for lifelong learning opportunities. But more than anything, this book spreads a message of hope: while there are no quick fixes, conscientious parents and committed educators can make a difference in every child's life, from infancy through childhood, and beyond.

Translational Research in Traumatic Brain Injury

Download Translational Research in Traumatic Brain Injury PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 1498766579
Total Pages : 388 pages
Book Rating : 4.4/5 (987 download)

DOWNLOAD NOW!


Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz

Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Everything You and Your Teachers Need to Know About the Learning Brain

Download Everything You and Your Teachers Need to Know About the Learning Brain PDF Online Free

Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889660265
Total Pages : 191 pages
Book Rating : 4.8/5 (896 download)

DOWNLOAD NOW!


Book Synopsis Everything You and Your Teachers Need to Know About the Learning Brain by : Sabine Peters

Download or read book Everything You and Your Teachers Need to Know About the Learning Brain written by Sabine Peters and published by Frontiers Media SA. This book was released on 2020-12-08 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Children go to school to learn, and learning takes place in the brain. In the age period of formal schooling, a child’s brain is still undergoing major developmental changes. For these reasons, neuroscience (the study of the brain) and education are closely connected. Learning is possible because the brain is plastic: plasticity refers to the capacity of the brain to reorganize its structure and thereby change function and behavior. But what exactly changes in the brain when we learn something new? What are optimal conditions for the brain to learn? Why do we also forget things? What developmental changes occur in the brain during childhood and adolescence, and how are these processes different or similar to the neural mechanisms of learning and memory? Neuro-imaging research, or ‘brain scanning’, has accelerated our current understanding of brain development, learning, memory and other school-related skills such as reading and math but also creativity, metacognition and learning-related emotions and anxieties. But what do these brain scanning techniques actually measure? What kind of questions can we address with neuro-imaging, and what are the limitations? In this Collection, we will provide an accessible overview of the current state-of-the-art insights into the mechanisms of brain development, learning and memory. The collection will help children understand how their brains learn and develop, and how these processes are shaped by their environment and their own efforts. Moreover, we will discuss why it is important that their teachers and other educational practitioners know about the brain and neuroscience methods. Finally, we will also explain what happens if wrong ideas about the brain circulate, or the correct knowledge is misinterpreted. Neuromyths such as ‘we only use 10 percent of our brain’ are persistent, but important to counter with explaining why they are false, and what is true instead.

Mapping the Brain and Its Functions

Download Mapping the Brain and Its Functions PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309044979
Total Pages : 180 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!


Book Synopsis Mapping the Brain and Its Functions by : Institute of Medicine

Download or read book Mapping the Brain and Its Functions written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant advances in brain research have been made, but investigators who face the resulting explosion of data need new methods to integrate the pieces of the "brain puzzle." Based on the expertise of more than 100 neuroscientists and computer specialists, this new volume examines how computer technology can meet that need. Featuring outstanding color photography, the book presents an overview of the complexity of brain research, which covers the spectrum from human behavior to genetic mechanisms. Advances in vision, substance abuse, pain, and schizophrenia are highlighted. The committee explores the potential benefits of computer graphics, database systems, and communications networks in neuroscience and reviews the available technology. Recommendations center on a proposed Brain Mapping Initiative, with an agenda for implementation and a look at issues such as privacy and accessibility.

Child Psychology

Download Child Psychology PDF Online Free

Author :
Publisher : Oxford University Press, USA
ISBN 13 : 0199646597
Total Pages : 153 pages
Book Rating : 4.1/5 (996 download)

DOWNLOAD NOW!


Book Synopsis Child Psychology by : Usha C. Goswami

Download or read book Child Psychology written by Usha C. Goswami and published by Oxford University Press, USA. This book was released on 2014 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume tracks child development from birth to early adolescence. Exploring the process of attachment and psychological relationships, as well as methods of active learning, including language and reasoning, Usha Goshwami explains how children develop as they do and how we can understand developmental differences.

Neural Plasticity and Memory

Download Neural Plasticity and Memory PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 1420008412
Total Pages : 368 pages
Book Rating : 4.4/5 (2 download)

DOWNLOAD NOW!


Book Synopsis Neural Plasticity and Memory by : Federico Bermudez-Rattoni

Download or read book Neural Plasticity and Memory written by Federico Bermudez-Rattoni and published by CRC Press. This book was released on 2007-04-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq

The Leading Brain

Download The Leading Brain PDF Online Free

Author :
Publisher : Penguin
ISBN 13 : 1101993200
Total Pages : 338 pages
Book Rating : 4.1/5 (19 download)

DOWNLOAD NOW!


Book Synopsis The Leading Brain by : Friederike Fabritius

Download or read book The Leading Brain written by Friederike Fabritius and published by Penguin. This book was released on 2017-02-21 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: A cutting-edge guide to applying the latest research in brain science to leadership - to sharpen performance, encourage innovation, and enhance job satisfaction. **Featured on NPR, Success, Investor Business Daily, Thrive Global, MindBodyGreen, The Chicago Tribune, and more** There's a revolution taking place that most businesses are still unaware of. The understanding of how our brains work has radically shifted, exploding long-held myths about our everyday cognitive performance and fundamentally changing the way we engage and succeed in the workplace. Combining their expertise in both neuropsychology and management consulting, neuropsychologist Friederike Fabritius and leadership expert Dr. Hans W. Hagemann present simple yet powerful strategies for: - Sharpening focus - Achieving the highest performance - Learning and retaining information more efficiently - Improving complex decision-making - Cultivating trust and building strong teams Based on the authors' popular leadership programs, which have been delivered to tens of thousands of leaders all over the world, this clear, insightful, and engaging book will help both individuals and teams perform at their maximum potential, delivering extraordinary results. **Named a Best Business Book of 2017 by Strategy+Business**

Environmental Neurotoxicology

Download Environmental Neurotoxicology PDF Online Free

Author :
Publisher : National Academies Press
ISBN 13 : 0309045312
Total Pages : 167 pages
Book Rating : 4.3/5 (9 download)

DOWNLOAD NOW!


Book Synopsis Environmental Neurotoxicology by : National Research Council

Download or read book Environmental Neurotoxicology written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.

Facing Addiction in America

Download Facing Addiction in America PDF Online Free

Author :
Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781974580620
Total Pages : 420 pages
Book Rating : 4.5/5 (86 download)

DOWNLOAD NOW!


Book Synopsis Facing Addiction in America by : Office of the Surgeon General

Download or read book Facing Addiction in America written by Office of the Surgeon General and published by Createspace Independent Publishing Platform. This book was released on 2017-08-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: All across the United States, individuals, families, communities, and health care systems are struggling to cope with substance use, misuse, and substance use disorders. Substance misuse and substance use disorders have devastating effects, disrupt the future plans of too many young people, and all too often, end lives prematurely and tragically. Substance misuse is a major public health challenge and a priority for our nation to address. The effects of substance use are cumulative and costly for our society, placing burdens on workplaces, the health care system, families, states, and communities. The Report discusses opportunities to bring substance use disorder treatment and mainstream health care systems into alignment so that they can address a person's overall health, rather than a substance misuse or a physical health condition alone or in isolation. It also provides suggestions and recommendations for action that everyone-individuals, families, community leaders, law enforcement, health care professionals, policymakers, and researchers-can take to prevent substance misuse and reduce its consequences.