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Chemical Probes In Biology Science At The Interface Of Chemistry Biology And Medicine
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Book Synopsis Chemical Probes in Biology by : Manfred P. Schneider
Download or read book Chemical Probes in Biology written by Manfred P. Schneider and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: This NATO Advanced Study Institute (co-sponsored by FEBS and INTAS) under the title "Chemical Probes in Biology" was designed to summarize and disseminate recent expert knowledge regarding a deeper understanding ofbiological phenomena on a molecular level. Such scientific activities -frequently termed Bio-organic Chemistry or Chemical Biology are constituting a highly interdisciplinary branch of chemistry beyond the traditional ways in which chemists and biologists have been working in the past. Thus, on this occasion we were bringing together senior experts from the disciplines of Chemistry and Biology in order to amalgamate their diverse yet basically common interests in this area. Ultimate goal was - next to an exchange of information between the two scientific cultures - the communication ofexciting possibilities in interdisciplinary research to the young scientists present. The meeting was held in the Anargyros and Korgialenios School on the Island ofSpeteses, Greece from 18-30 August 2002. The ASI was attended by a total of 91 scholars from 23 different countries. A group of 27 speakers presented a series of 34 highly stimulating, informative and educational lectures covering a broad range of topics relevant to the general theme ofthis meeting: Science at the InteifaceofChemistry, Biology and Medicine. The lectures were complemented by a total of 89 posters presented by the young scholars and a series of short lectures derived thereof This was clearly one ofthe highlites of the meeting creating a lively atmosphere of interaction and intellectual creativity - typical phenomena for the whole meeting.
Book Synopsis Chemical Probes in Biology by : Philip J. Snodgrass
Download or read book Chemical Probes in Biology written by Philip J. Snodgrass and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ornithine Transcarbamylase: Basic Science and Clinical Considerations, written by a leading expert on OTC, for the first time assembles and analyzes more than 40 years of basic science and clinical research. It will be the definitive resource on the topic for pediatricians, geneticists, and internists who care for patients with OTC deficiency, as well as for basic scientists and genetic researchers who study the urea cycle in mammals and the arginine biosynthetic pathway in bacteria and fungi.
Book Synopsis Chemical Genomics by : Stefan Jaroch
Download or read book Chemical Genomics written by Stefan Jaroch and published by Springer Science & Business Media. This book was released on 2007-05-26 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical genomics is a highly interdisciplinary and very exciting field of research both in academics and in the life sciences industry. The Ernst Schering Research Foundation Workshop 58 was organized to bring together scientific leaders in the field to discuss the implications of chemical genomics for drug discovery. Various aspects of the interface between chemistry and biology are covered in this volume, such as chemogenomics efforts in the pharmaceutical industry, diversity-oriented synthesis, chemogenomic approaches to the study of cell function, screening technologies, and natural products as tools in chemical biology.
Book Synopsis The Discovery and Utility of Chemical Probes in Target Discovery by : Paul Brennan
Download or read book The Discovery and Utility of Chemical Probes in Target Discovery written by Paul Brennan and published by Royal Society of Chemistry. This book was released on 2020-11-17 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous genetic methods can be utilised to link a phenotype to a single molecular target but annotated small molecule chemical probes and even entire chemogenomic libraries are increasingly being used as a complementary approach. This book will comprehensively cover the state of the art in chemical probes and best practice for use in target discovery, illustrated throughout with examples. Ideal for students and established biochemists, the book will also cover new technologies for probe discovery, new probe modalities, the new field of probes for RNA targets and the mature field of kinase chemical probes.
Book Synopsis Chemical Genomics by : Stefan Jaroch
Download or read book Chemical Genomics written by Stefan Jaroch and published by Springer. This book was released on 2009-09-02 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical genomics is a highly interdisciplinary and very exciting field of research both in academics and in the life sciences industry. The Ernst Schering Research Foundation Workshop 58 was organized to bring together scientific leaders in the field to discuss the implications of chemical genomics for drug discovery. Various aspects of the interface between chemistry and biology are covered in this volume, such as chemogenomics efforts in the pharmaceutical industry, diversity-oriented synthesis, chemogenomic approaches to the study of cell function, screening technologies, and natural products as tools in chemical biology.
Book Synopsis New Frontiers in Chemical Biology by : Mark E. Bunnage
Download or read book New Frontiers in Chemical Biology written by Mark E. Bunnage and published by Royal Society of Chemistry. This book was released on 2011 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the new frontiers in chemical biology and describes their impact and future potential in drug discovery.
Book Synopsis Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Methods for Prokaryotic and Eukaryotic Systems by :
Download or read book Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Methods for Prokaryotic and Eukaryotic Systems written by and published by Academic Press. This book was released on 2020-05-14 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Methods for Prokaryotic and Eukaryotic Systems, Volume 638, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sample chapters from this new release include In vitro characterization of the colibactin-activating peptidase ClbP enables development of a fluorogenic activity probe, Using FDAA probes to study cell division in Bacillus subtilis, Chemoenzymatic synthesis of UDP-sugars, Chemical tools for selective activity profiling of bacterial penicillin-binding proteins, Chemical Probes Reveal and Extraseptal Mode of Cross-linking in Staphylococcus Aureus, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series Includes the latest information on retinoid signaling pathways
Book Synopsis Wiley Encyclopedia of Chemical Biology, Volume 2 by : Tadhg P. Begley
Download or read book Wiley Encyclopedia of Chemical Biology, Volume 2 written by Tadhg P. Begley and published by Wiley-Blackwell. This book was released on 2009-02-03 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the cell and is the fundamental science of drug discovery, playing a key role in the development of novel agents for the prevention, diagnosis, and treatment of disease. Now students and researchers across the range of disciplines that use chemical biology techniques have a single resource that encapsulates what is known in the field. It is an excellent place to begin any chemical biology investigation. Major topics addressed in the encyclopedia include: Applications of chemical biology Biomolecules within the cell Chemical views of biology Chemistry of biological processes and systems Synthetic molecules as tools for chemical biology Technologies and techniques in chemical biology Some 300 articles range from pure basic research to areas that have immediate applications in fields such as drug discovery, sensor technology, and catalysis. Novices in the field can turn to articles that introduce them to the basics, whereas experienced researchers have access to articles exploring the cutting edge of the science. Each article ends with a list of references to facilitate further investigation. With contributions from leading researchers and pioneers in the field, the Wiley Encyclopedia of Chemical Biology builds on Wiley's unparalleled reputation for helping students and researchers understand the crucial role of chemistry and chemical techniques in the life sciences.
Download or read book Proteins, Enzymes, Genes written by and published by Yale University Press. This book was released on with total page 814 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book a distinguished scientist-historian offers a critical account of how biochemistry and molecular biology emerged as major scientific disciplines from the interplay of chemical and biological ideas and practice. Joseph S. Fruton traces the historical development of these disciplines from antiquity to the present time, examines their institutional settings, and discusses their impact on medical, pharmaceutical, and agricultural practice.
Book Synopsis Innovations in Chemical Biology by : Bilge Sener
Download or read book Innovations in Chemical Biology written by Bilge Sener and published by Springer Science & Business Media. This book was released on 2008-11-23 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes 49 chapters presented as plenary , invited lectures and posters at the conference. Six plenary lectures have published in an issue of Pure and Applied Chemistry, Vol. 79, No. 12, 2007; the titles of these presentations are given as an Annex at the end of the book. I thank all contrib utors for the preparation of their presentations. It is sad to report that Professor Hitoshi Ohtaki, one of the founders of the Eurasia conferences and contributors passed away on November 5, 2006. Professor Ohtaki enthusiastically promoted international cooperation and took it upon himself to p- licize Japanese science to the wider world. His contribution in this book will serve as a memorable contribution to that goal. He will be missed by all of us. This book is dedicated to his memory. Professor Dr . Bilge S ̧ ener Editor Memorial Tribute to Professor Dr. Hitoshi Ohtaki Curriculum Vitae of Hitoshi Ohtaki Date of Birth September 16, 1932 Place of Birth T ok yo, Japan Date of Decease November 5, 2006 (at the age of 74) Addr ess 3-9-406 Namiki-2-chome, Kanazawa-ku, Yokohama, Japan Institution Chair Professor of The Research Organization of Science and Engineering, Ritsumeikan University Guest Professor of Yokohama City University Education Bachelor of Science, Nagoya University, 1955 Master of Science, Nagoya University, 1957 Doctor of Science, Nagoya University, 1961 ix x Memorial Tribute to Professor Dr.
Book Synopsis Phosphate Labeling and Sensing in Chemical Biology by : Henning Jacob Jessen
Download or read book Phosphate Labeling and Sensing in Chemical Biology written by Henning Jacob Jessen and published by Springer. This book was released on 2017-07-08 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
Book Synopsis Advances in Chemical Biology – An Overview of Research Milestones and Applications (Volume – II) Book by : Dr. Sadashiv S. O.
Download or read book Advances in Chemical Biology – An Overview of Research Milestones and Applications (Volume – II) Book written by Dr. Sadashiv S. O. and published by Shineeks Publishers. This book was released on 2023-10-20 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current book emphasizes on basic knowledge of chemistry and biology concepts, covering multidisciplinary applications which comprises functional aspects of chemical and biological disciplines and they are resource material for young innovative minds to enhance their knowledge and research thoughts as a creative element to apply it in their research in the field of chemical biology. The main motto of this book highlights on research objectives, new developments of synthesis, a wide range of applications, and as per the industrial requirements for a useful product to launch or discover for science and society. Various innovations are the major source and new perspectives to troubleshoot the newer problems with the help of allied science applications by understanding the basic concepts, theories, protocols, needful technologies, and applied products, by knowing similar problems and their impact in current-day problems in the science field. Hence, it’s interdisciplinary research to develop highly significant pharmacology products in the areas of life science to make sure safer, cheaper, and ecological as a novel future drug/medicine. The applications aimed mainly to health of humans, health of agro-horticulture, health of environment and animalsas well as wealth of entrepreneurs. This comprehensive edited volume summarises the features of An Approach to Future Perspectives for academic, research and industrial purposes as an advanced reference material for all the learners in the area of chemistry and biology.
Book Synopsis Advances in Chemical Bioanalysis by : Frank-Michael Matysik
Download or read book Advances in Chemical Bioanalysis written by Frank-Michael Matysik and published by Springer. This book was released on 2014-06-03 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert authors provide critical, in-depth reviews of available methods for retrieving selective information out of complex biological systems. Sensors, probes and devices are present and future tools of medicinal diagnostics, environmental monitoring, food analysis and molecular biology. These are based on fluorescence, electrochemistry and mass spectrometry. Coverage of this volume includes sensor development for the detection of small analytes, monitoring of biomolecular interactions, analysis of cellular function, development of diagnostic tools.
Book Synopsis Chemical Biology by : Natanya Civjan
Download or read book Chemical Biology written by Natanya Civjan and published by John Wiley & Sons. This book was released on 2012-08-07 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative look at the application of chemical biology in drug discovery and development Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development. The first part of the book reviews key principles and techniques used in the design and evaluation of drug candidates. The second part elucidates biological mechanisms of certain diseases, illuminating approaches to investigate and target these diseases. Comprising carefully selected reprints from the Encyclopedia as well as new contributions from leading scholars in the field, this book provides researchers in academia and industry with important information to aid in the development of novel agents to treat disease. Self-contained articles cover a variety of essential topics, including: The design, development, and optimization of drug candidates The pharmacokinetics and properties of drugs Drug transport and delivery Natural products and natural product models as pharmaceuticals Biological mechanisms underlying health and disease Treatment strategies for a range of diseases, from HIV to schizophrenia Chemical Biology is a top-notch guide and reference for anyone working in the areas of drug discovery and development, including researchers in chemical biology and other fields such as biochemistry, medicine, and pharmaceutical sciences.
Book Synopsis Chemistry and Chemical Biology by : Roman Joswik
Download or read book Chemistry and Chemical Biology written by Roman Joswik and published by CRC Press. This book was released on 2014-09-19 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important volume highlights the latest developments and trends in chemistry, biochemistry, and biology. It presents the developments of advanced materials and respective tools to characterize and predict the material properties and behavior. The book provides original, theoretical, and important experimental results that use non-routine method
Book Synopsis Flow and Microreactor Technology in Medicinal Chemistry by : Esther Alza
Download or read book Flow and Microreactor Technology in Medicinal Chemistry written by Esther Alza and published by John Wiley & Sons. This book was released on 2022-06-13 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to master a powerful technology to enable a faster drug discovery workflow The ultimate dream for medicinal chemists is the ability to synthesize new drug-like compounds with the push of a button. The key to synthesizing chemical compounds more quickly and accurately lies in computer-controlled technologies that can be optimized by machine learning. Recent developments in computer-controlled automated syntheses that rely on miniature flow reactors—with integrated analysis of the resulting products—provide a workable technology for synthesizing new chemical substances very quickly and with minimal effort. In Flow and Microreactor Technology in Medicinal Chemistry, early adopters of this ground-breaking technology describe its current and potential uses in medicinal chemistry. Based on successful examples of the use of flow and microreactor synthesis for drug-like compounds, the book introduces current as well as emerging uses for automated synthesis in a drug discovery context. Flow and Microreactor Technology in Medicinal Chemistry readers will also find: Numerous case studies that address the most common applications of this technology in the day-to-day work of medicinal chemists How to integrate flow synthesis with drug discovery How to perform enantioselective reactions under continuous flow conditions Flow and Microreactor Technology in Medicinal Chemistry is a valuable practical reference for medicinal chemists, organic chemists, and natural products chemists, whether they are working in academia or in the pharmaceutical industry.
Book Synopsis Photochemical Probes in Biochemistry by : Peter E. Nielsen
Download or read book Photochemical Probes in Biochemistry written by Peter E. Nielsen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of using photochemical probes in the study of biological systems was developed by Westheimer who published the first photoaffinity labeling experiments more than twenty years ago (J.Bio1. Chem. 237, (1962) 3006). Since then the concept has been used successfully in various areas of biochemistry and recently several new interesting and exciting aspects of the concept have been developed. It is the general opinion by scientists in the "field" that the full potential of photochemical probes in biochemical studies has far from been exploited yet. This is mostly due to the interdisciplinary character of the concept involving photochemistry, synthetic chemistry as well as biochemistry/molecular biology. The perspective of the NATO advanced workshop on "Photochemical Probes in Biochemistry", held in Holte (Copenhagen) Denmark 14-19, August, 1988, was several fold. The workshop was to give an account of the "state of the art" of using photochemical probes in biochemistry as well as to bring together specialists in photochemistry, syn thetic chemistry and molecular biology in order to analyze advantages as well as the inherent problems and pitfalls of the concept and provide suggestions and guidelines for fu ture research. Furthermore, it is the hope of the editor that the present publication which gives an account of the lectures presented at the workshop, will provide an introduction to scientists who are not familiar with photochemical probes, but to whom these could help answer central and pertinent questions.
