Changing Connectomes

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Changing Connectomes

Author : Marcus Kaiser
Publisher : MIT Press
ISBN 13 : 0262044617
Total Pages : 271 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Changing Connectomes by : Marcus Kaiser

Download or read book Changing Connectomes written by Marcus Kaiser and published by MIT Press. This book was released on 2020-09-08 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date overview of the field of connectomics, introducing concepts and mechanisms underlying brain network change at different stages. The human brain undergoes massive changes during its development, from early childhood and the teenage years to adulthood and old age. Across a wide range of species, from C. elegans and fruit flies to mice, monkeys, and humans, information about brain connectivity (connectomes) at different stages is now becoming available. New approaches in network neuroscience can be used to analyze the topological, spatial, and dynamical organization of such connectomes. In Changing Connectomes, Marcus Kaiser provides an up-to-date overview of the field of connectomics and introduces concepts and mechanisms underlying brain network changes during evolution and development. Drawing on a range of results from experimental, clinical, and computational studies, Kaiser describes changes during healthy brain maturation and during brain network disorders (including such neurodevelopmental conditions as schizophrenia and depression), brain injury, and neurodegenerative disorders including dementia. He argues that brain stimulation is an area where understanding connectome development could help in assessing long-term effects of interventions. Changing Connectomes is a suitable starting point for researchers who are new to the field of connectomics, and also for researchers who are interested in the link between brain network organization and brain and cognitive development in health and disease. Matlab/Octave code examples available at the MIT Press website will allow computational neuroscience researchers to understand and extend the shown mechanisms of connectome development.

Connectome

Author : Sebastian Seung
Publisher : HMH
ISBN 13 : 0547508174
Total Pages : 389 pages
Book Rating : 4.5/5 (475 download)

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Book Synopsis Connectome by : Sebastian Seung

Download or read book Connectome written by Sebastian Seung and published by HMH. This book was released on 2012-02-07 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Accessible, witty . . . an important new researcher, philosopher and popularizer of brain science . . . on par with cosmology’s Brian Greene and the late Carl Sagan” (The Plain Dealer). One of the Wall Street Journal’s 10 Best Nonfiction Books of the Year and a Publishers Weekly “Top Ten in Science” Title Every person is unique, but science has struggled to pinpoint where, precisely, that uniqueness resides. Our genome may determine our eye color and even aspects of our character. But our friendships, failures, and passions also shape who we are. The question is: How? Sebastian Seung is at the forefront of a revolution in neuroscience. He believes that our identity lies not in our genes, but in the connections between our brain cells—our particular wiring. Seung and a dedicated group of researchers are leading the effort to map these connections, neuron by neuron, synapse by synapse. It’s a monumental effort, but if they succeed, they will uncover the basis of personality, identity, intelligence, memory, and perhaps disorders such as autism and schizophrenia. Connectome is a mind-bending adventure story offering a daring scientific and technological vision for understanding what makes us who we are, as individuals and as a species. “This is complicated stuff, and it is a testament to Dr. Seung’s remarkable clarity of exposition that the reader is swept along with his enthusiasm, as he moves from the basics of neuroscience out to the farthest regions of the hypothetical, sketching out a spectacularly illustrated giant map of the universe of man.” —TheNew York Times “An elegant primer on what’s known about how the brain is organized and how it grows, wires its neurons, perceives its environment, modifies or repairs itself, and stores information. Seung is a clear, lively writer who chooses vivid examples.” —TheWashington Post

Changing Connectomes

Author : Marcus Kaiser
Publisher : MIT Press
ISBN 13 : 0262360810
Total Pages : 271 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis Changing Connectomes by : Marcus Kaiser

Connectome

Author : Sebastian Seung
Publisher : Houghton Mifflin Harcourt
ISBN 13 : 0547508182
Total Pages : 389 pages
Book Rating : 4.5/5 (475 download)

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Book Synopsis Connectome by : Sebastian Seung

Download or read book Connectome written by Sebastian Seung and published by Houghton Mifflin Harcourt. This book was released on 2012 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: The audacious effort to map the brain--and along with it mental afflictions, from autism to schizophrenia--by a rising star in neuroscience.

Micro-, Meso- and Macro-Connectomics of the Brain

Author : Henry Kennedy
Publisher : Springer
ISBN 13 : 3319277774
Total Pages : 173 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Micro-, Meso- and Macro-Connectomics of the Brain by : Henry Kennedy

Download or read book Micro-, Meso- and Macro-Connectomics of the Brain written by Henry Kennedy and published by Springer. This book was released on 2016-03-10 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.

Infection Prevention and Control

Author : Paul Elliott
Publisher : CRC Press
ISBN 13 : 1315346079
Total Pages : 220 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Infection Prevention and Control by : Paul Elliott

Download or read book Infection Prevention and Control written by Paul Elliott and published by CRC Press. This book was released on 2017-12-04 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a variety of perceptions of and perspectives on infection prevention and control. In doing this, the chapters will reflect upon challenging and controversial new ways of looking at infection prevention and control aimed at generating both discussion and debate as well as practical solutions. With this in mind, the book will aim not only to challenge the existing status quo but also push the frontiers of knowledge, thinking and practice where infection prevention and control is concerned. This is vital when considered in the light of cross infection rates, the number of healthcare providers who are being identified by the Care Quality Commission as falling below acceptable standards of infection prevention and control and the almost compulsive persistent non-adherent behaviours of those involved in the provision of medicine, health, social care and other disciplines related to caring with regards to the undertaking of safe and appropriate standards of infection prevention and control. There is no doubt that this book will be challenging with regards to the readers' perceptions and perspectives of infection prevention and control. Where this topic is concerned however, such a challenging approach is vital if the health, safety and well being of individuals is to be positively promoted among all those involved in the health and wellbeing of others.

The Pyramid Approach

Author : George Woodrow
Publisher : Rowman & Littlefield
ISBN 13 : 147581352X
Total Pages : 233 pages
Book Rating : 4.4/5 (758 download)

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Book Synopsis The Pyramid Approach by : George Woodrow

Download or read book The Pyramid Approach written by George Woodrow and published by Rowman & Littlefield. This book was released on 2014-10-08 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains why virtually all children can achieve proficiency or higher. And it gives educators the tools to help them achieve those levels of learning. The notion that schools are “waiting for Superman” or Wonder Woman to rescue them is at best a fantasy and at worst, damaging to schools and school systems that advance this type of flawed thinking. This is why in this book the reader will be encouraged to embrace the concept that only through building effective teams (collective instructional leadership) will schools begin to realize their stated goal—educate “all” students. It may take a village to raise children but it takes collective instructional leadership to educate them. This book takes great care to ask the questions that policymakers, educators, parents, students and the larger community want answered: Can you handle the truth? Why is team leadership needed? How do campuses improve their team dynamics? What methods do high performing nations use to excel? What strategies really work in high poverty schools? Where do American schools rank on the rigor scale? What is trust and how is it developed? What are campus learning disabilities? How do beliefs about human capacity affect student achievement levels? What methods motivate students to work hard? What do we really mean when we say, “All children can learn”? The Pyramid Approach was designed by Dr. George Woodrow, Jr. for use by educators. The Pyramid is research-based; it aligns theory with professional practice. In addition, it strives to take what we know and provide a practical framework to effectively apply that same knowledge in ways that promotes student achievement. The Pyramid Approach calls attention to the need for a systematic framework that recognizes the interconnectedness among research methods.

Bio-Inspired Information Pathways

Author : Martin Ziegler
Publisher : Springer Nature
ISBN 13 : 3031367057
Total Pages : 439 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Bio-Inspired Information Pathways by : Martin Ziegler

Download or read book Bio-Inspired Information Pathways written by Martin Ziegler and published by Springer Nature. This book was released on with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt:

From Electrons to Elephants and Elections

Author : Shyam Wuppuluri
Publisher : Springer Nature
ISBN 13 : 3030921921
Total Pages : 886 pages
Book Rating : 4.0/5 (39 download)

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Book Synopsis From Electrons to Elephants and Elections by : Shyam Wuppuluri

Download or read book From Electrons to Elephants and Elections written by Shyam Wuppuluri and published by Springer Nature. This book was released on 2022-04-08 with total page 886 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly interdisciplinary book, covering more than six fields, from philosophy and sciences all the way up to the humanities and with contributions from eminent authors, addresses the interplay between content and context, reductionism and holism and their meeting point: the notion of emergence. Much of today’s science is reductionist (bottom-up); in other words, behaviour on one level is explained by reducing it to components on a lower level. Chemistry is reduced to atoms, ecosystems are explained in terms of DNA and proteins, etc. This approach fails quickly since we can’t cannot extrapolate to the properties of atoms solely from Schrödinger's equation, nor figure out protein folding from an amino acid sequence or obtain the phenotype of an organism from its genotype. An alternative approach to this is holism (top-down). Consider an ecosystem or an organism as a whole: seek patterns on the same scale. Model a galaxy not as 400 billion-point masses (stars) but as an object in its own right with its own properties (spiral, elliptic). Or a hurricane as a structured form of moist air and water vapour. Reductionism is largely about content, whereas holistic models are more attuned to context. Reductionism (content) and holism (context) are not opposing philosophies — in fact, they work best in tandem. Join us on a journey to understand the multifaceted dialectic concerning this duo and how they shape the foundations of sciences and humanities, our thoughts and, the very nature of reality itself.

Contemporary Natural Philosophy and Philosophies - Part 1

Author : Gordana Dodig-Crnkovic
Publisher : MDPI
ISBN 13 : 3038978221
Total Pages : 350 pages
Book Rating : 4.0/5 (389 download)

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Book Synopsis Contemporary Natural Philosophy and Philosophies - Part 1 by : Gordana Dodig-Crnkovic

Download or read book Contemporary Natural Philosophy and Philosophies - Part 1 written by Gordana Dodig-Crnkovic and published by MDPI. This book was released on 2019-06-11 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern information communication technology eradicates barriers of geographic distances, making the world globally interdependent, but this spatial globalization has not eliminated cultural fragmentation. The Two Cultures of C.P. Snow (that of science–technology and that of humanities) are drifting apart even faster than before, and they themselves crumble into increasingly specialized domains. Disintegrated knowledge has become subservient to the competition in technological and economic race leading in the direction chosen not by the reason, intellect, and shared value-based judgement, but rather by the whims of autocratic leaders or fashion controlled by marketers for the purposes of political or economic dominance. If we want to restore the authority of our best available knowledge and democratic values in guiding humanity, first we have to reintegrate scattered domains of human knowledge and values and offer an evolving and diverse vision of common reality unified by sound methodology. This collection of articles responds to the call from the journal Philosophies to build a new, networked world of knowledge with domain specialists from different disciplines interacting and connecting with other knowledge-and-values-producing and knowledge-and-values-consuming communities in an inclusive, extended, contemporary natural–philosophic manner. In this process of synthesis, scientific and philosophical investigations enrich each other—with sciences informing philosophies about the best current knowledge of the world, both natural and human-made—while philosophies scrutinize the ontological, epistemological, and methodological foundations of sciences, providing scientists with questions and conceptual analyses. This is all directed at extending and deepening our existing comprehension of the world, including ourselves, both as humans and as societies, and humankind.

Emergence in Context

Author : Robert C. Bishop
Publisher : Oxford University Press
ISBN 13 : 0192666630
Total Pages : 360 pages
Book Rating : 4.1/5 (926 download)

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Book Synopsis Emergence in Context by : Robert C. Bishop

Download or read book Emergence in Context written by Robert C. Bishop and published by Oxford University Press. This book was released on 2022-06-20 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science, philosophy of science, and metaphysics have long been concerned with the question of how order, stability, and novelty are possible and how they happen. How can order come out of disorder? This book introduces a new account, contextual emergence, seeking to answer these questions. The authors offer an alternative picture of the world with an alternative account of how novelty and order arise, and how both are possible. Contextual emergence is grounded primarily in the sciences as opposed to logic or metaphysics. It is both an explanatory and ontological account of emergence that gets beyond the impasse between “weak” and “strong” emergence in the emergence debates. It challenges the “foundationalist” or hierarchical picture of reality and emphasizes the ontological and explanatory fundamentality of multiscale stability conditions and their contextual constraints, often operating globally over interconnected, interdependent, and interacting entities and their multiscale relations. It also focuses on the conditions that make the existence, stability, and persistence of emergent systems and their states and observables possible. These conditions and constraints are irreducibly multiscale relations, so it is not surprising that scientific explanation is often multiscale. Such multiscale conditions act as gatekeepers for systems to access modal possibilities (e.g., reducing or enhancing a system's degrees of freedom). Using examples from across the sciences, ranging from physics to biology to neuroscience and beyond, this book demonstrates that there is an empirically well-grounded, viable alternative to ontological reductionism coupled with explanatory anti-reductionism (weak emergence) and ontological disunity coupled with the impossibility of robust scientific explanation (strong emergence). Central metaphysics of science concerns are also addressed. Emergence in Context: A Treatise in Twenty-First Century Natural Philosophy is written primarily for philosophers of science, but also professional scientists from multiple disciplines who are interested in emergence and particularly in the metaphysics of science.

Connectome Analysis

Author : Markus D. Schirmer
Publisher : Academic Press
ISBN 13 : 0323852815
Total Pages : 480 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Connectome Analysis by : Markus D. Schirmer

Download or read book Connectome Analysis written by Markus D. Schirmer and published by Academic Press. This book was released on 2023-06-30 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connectome Analysis: Characterization, Methods, and Analysis is a comprehensive companion for the analysis of brain networks, or connectomes. The book provides sources of constituent structural and functional MRI signals, network construction and practices for analysis, cutting-edge methods that address the latest challenges in neuroscience, and the fundamentals of network theory in the context of giving practical methods for building connectomes for analysis. Emphasis is placed on quality control of the individual analysis steps. Subsequent chapters discuss networks in neuroscience in clinical and general populations, including how findings are related to underlying neurophysiology and neuropsychology. This book is aimed at students and early-career researchers in brain connectomics and neuroimaging who have a background in computer science, mathematics and physics, as well as more broadly to neuroscientists and psychologists who want to start incorporating connectomics into their research. - Provides practical recommendations on how to construct, assess and analyze brain networks - Gives an understanding of all the technical methods for connectome analysis - Presents the basic network theoretical principles typically used in neuroscience - Covers the latest tools and data repositories that are freely available for the reader to carry out connectomic analyses

Mapping the connectome: Multi-level analysis of brain connectivity

Author : Trygve B. Leergaard
Publisher : Frontiers E-books
ISBN 13 : 2889191079
Total Pages : 251 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Mapping the connectome: Multi-level analysis of brain connectivity by : Trygve B. Leergaard

Download or read book Mapping the connectome: Multi-level analysis of brain connectivity written by Trygve B. Leergaard and published by Frontiers E-books. This book was released on with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Discovering the Human Connectome

Author : Olaf Sporns
Publisher : MIT Press
ISBN 13 : 0262017903
Total Pages : 253 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Discovering the Human Connectome by : Olaf Sporns

Download or read book Discovering the Human Connectome written by Olaf Sporns and published by MIT Press. This book was released on 2012-08-31 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: A pioneer in the field outlines new empirical and computational approaches to mapping the neural connections of the human brain. Crucial to understanding how the brain works is connectivity, and the centerpiece of brain connectivity is the connectome, a comprehensive description of how neurons and brain regions are connected. In this book, Olaf Sporns surveys current efforts to chart these connections—to map the human connectome. He argues that the nascent field of connectomics has already begun to influence the way many neuroscientists collect, analyze, and think about their data. Moreover, the idea of mapping the connections of the human brain in their entirety has captured the imaginations of researchers across several disciplines including human cognition, brain and mental disorders, and complex systems and networks. Discovering the Human Connectome offers the first comprehensive overview of current empirical and computational approaches in this rapidly developing field.

Connectomic Deep Brain Stimulation

Author : Andreas Horn
Publisher : Academic Press
ISBN 13 : 0128218622
Total Pages : 602 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Connectomic Deep Brain Stimulation by : Andreas Horn

Download or read book Connectomic Deep Brain Stimulation written by Andreas Horn and published by Academic Press. This book was released on 2021-09-10 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connectomic Deep Brain Stimulation (DBS) covers this highly efficacious treatment option for movement disorders such as Parkinson's Disease, Essential Tremor and Dystonia. The book examines its impact on distributed brain networks that span across the human brain in parallel with modern-day neuroimaging concepts and the connectomics of the brain. It asks several questions, including which cortical areas should DBS electrodes be connected in order to generate the highest possible clinical improvement? Which connections should be avoided? Could these connectomic insights be used to better understand the mechanism of action of DBS? How can they be transferred to individual patients, and more. This book is suitable for neuroscientists, neurologists and functional surgeons studying DBS. It provides practical advice on processing strategies and theoretical background, highlighting and reviewing the current state-of-the-art in connectomic surgery. - Written to provide a "hands-on" approach for neuroscience graduate students, as well as medical personnel from the fields of neurology and neurosurgery - Includes preprocessing strategies (such as co-registration, normalization, lead localization, VTA estimation and fiber-tracking approaches) - Presents references (key articles, books and protocols) for additional detailed study - Provides data analysis boxes in each chapter to help with data interpretation

Neuroanatomy of Human Brain Development

Author : Hao Huang
Publisher : Frontiers Media SA
ISBN 13 : 2889451208
Total Pages : 223 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Neuroanatomy of Human Brain Development by : Hao Huang

Download or read book Neuroanatomy of Human Brain Development written by Hao Huang and published by Frontiers Media SA. This book was released on 2017-03-07 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human brain is extraordinary complex and yet its origin is a simple tubular structure. Rapid and dramatic structural growth takes place during the fetal and perinatal period. By the time of birth, a repertoire of major cortical, subcortical and white matter structures resembling the adult pattern has emerged, however there are continued maturational changes of the gray matter and white matter throughout childhood and adolescence and into adulthood. The maturation of neuronal structures provides the neuroanatomical basis for the acquisition and refinement of cognitive functions during postnatal development. Histological imaging has been traditionally dominant in understanding neuroanatomy of early brain development and still plays an unparalleled role in this field. Modern magnetic resonance imaging (MRI) techniques including diffusion MRI, as noninvasive tools readily applied to in vivo brains, have become an important complementary approach in revealing the detailed brain anatomy, including the structural connectivity between brain regions. In this research topic, we presented the most recent investigations on understanding the neuroanatomy and connectivity of human brain development using both histology and MRI. Modern advances in mapping normal developmental brain anatomy and connectivity should elucidate many neurodevelopmental disorders, ranging from rare congenital malformations to common disorders such as autism and attention deficit hyperactivity disorder (ADHD), which is a prerequisite for better diagnosis and treatment of these currently poorly understood diseases.

Connectomic Medicine

Author : Michael E. Sughrue
Publisher : Elsevier
ISBN 13 : 0443190909
Total Pages : 308 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Connectomic Medicine by : Michael E. Sughrue

Download or read book Connectomic Medicine written by Michael E. Sughrue and published by Elsevier. This book was released on 2023-12-01 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connectomic Medicine: A Guide to Brain AI in Treatment Decision Planning examines how to apply connectomics to clinical medicine, including discussions on techniques, applications, novel ideas, and in case examples that highlight the state-of-the-art. Written by pioneers, this volume serves as the foundation for all neuroscience clinicians/researchers venturing into the field of AI medicine, its realistic applications, and how to integrate AI connectomics into clinical practice. With widespread applications in neurology, neurosurgery and psychiatry, this book is appropriate for anyone interested in cerebral network anatomy, imaging techniques, and insights into this emerging field. - Empowers readers to utilize clinically applicable AI platforms to enhance current neurological and psychiatric practices - Provides understanding on how brain connectomics pertain to patients with brain-related ailments - Serves as a guide towards maximally using existing connectomics software - Details relevant clinical and radiological background