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Cellular Hypoxia And Neuro Immune Fatigue
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Book Synopsis Cellular Hypoxia and Neuro-Immune Fatigue by : David S. Bell
Download or read book Cellular Hypoxia and Neuro-Immune Fatigue written by David S. Bell and published by WingSpan Press. This book was released on 2007 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic fatigue syndrome and fibromyalgia have severe and sometimes disabling symptoms, yet the affected patient looks well. In this book a mechanism is presented arguing that these illnesses are defined by decreased cellular energy production. This is not a book that describes the signs and symptoms of the illnesses; it is a book that explores mechanisms that lie beneath the complex symptom patterns. Dr. David Bell is a well recognized expert in chronic fatigue syndrome. He is the author of several books and was chairman of the Department of Health and Human Services Chronic Fatigue Syndrome Advisory Committee.
Download or read book Chronic Fatigue Syndrome written by and published by Erica Verrillo. This book was released on 19?? with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sandy Shaw presents a collection of resources on chronic fatigue syndrome (CFS). The resources include definitions, abstracts, and links to support groups, archives, publications, government agencies, universities, and more.
Book Synopsis Current Insights into Complex Post-Infection Fatigue Syndromes with Unknown Aetiology: the Case of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Beyond by : Nuno Sepulveda
Download or read book Current Insights into Complex Post-Infection Fatigue Syndromes with Unknown Aetiology: the Case of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Beyond written by Nuno Sepulveda and published by Frontiers Media SA. This book was released on 2022-03-15 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome by : Institute of Medicine
Download or read book Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome written by Institute of Medicine and published by National Academies Press. This book was released on 2015-03-16 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) are serious, debilitating conditions that affect millions of people in the United States and around the world. ME/CFS can cause significant impairment and disability. Despite substantial efforts by researchers to better understand ME/CFS, there is no known cause or effective treatment. Diagnosing the disease remains a challenge, and patients often struggle with their illness for years before an identification is made. Some health care providers have been skeptical about the serious physiological - rather than psychological - nature of the illness. Once diagnosed, patients often complain of receiving hostility from their health care provider as well as being subjected to treatment strategies that exacerbate their symptoms. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome proposes new diagnostic clinical criteria for ME/CFS and a new term for the illness - systemic exertion intolerance disease(SEID). According to this report, the term myalgic encephalomyelitis does not accurately describe this illness, and the term chronic fatigue syndrome can result in trivialization and stigmatization for patients afflicted with this illness. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome stresses that SEID is a medical - not a psychiatric or psychological - illness. This report lists the major symptoms of SEID and recommends a diagnostic process.One of the report's most important conclusions is that a thorough history, physical examination, and targeted work-up are necessary and often sufficient for diagnosis. The new criteria will allow a large percentage of undiagnosed patients to receive an accurate diagnosis and appropriate care. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome will be a valuable resource to promote the prompt diagnosis of patients with this complex, multisystem, and often devastating disorder; enhance public understanding; and provide a firm foundation for future improvements in diagnosis and treatment.
Book Synopsis Reversibility of Chronic Disease and Hypersensitivity by : William J. Rea
Download or read book Reversibility of Chronic Disease and Hypersensitivity written by William J. Rea and published by CRC Press. This book was released on 2014-08-15 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedic in scope, Reversibility of Chronic Degenerative Disease and Hypersensitivity, Volume 2: The Effects of Environmental Pollutants on the Organ System draws deeply from clinical histories of thousands of patients. It focuses on clinical syndromes within the musculoskeletal, gastrointestinal, and respiratory systems. The book explores mechanisms of chemical sensitivity and chronic degenerative disease as well as the triggering agents of musculoskeletal, gastrointestinal, and sino-respiratory diseases. It then discusses triggering agents such as natural gas, pesticides, solvents, and micotoxins. The authors include new data for indoor and outdoor air pollution that harms the chemically sensitive and chronic degenerative diseased patient as well as new data for breath analysis. They also describe the physiology of chemical sensitivity and chronic degenerative diseases, their manifestations, diagnosis, and approaches to reverse dysfunction. The second volume of a five-volume set, the book provides an essential resource for health care providers diagnosing and treating chemical sensitivity and chronic degenerative disease.
Book Synopsis Reversibility of Chronic Disease and Hypersensitivity,Volume 2 by : William J. Rea
Download or read book Reversibility of Chronic Disease and Hypersensitivity,Volume 2 written by William J. Rea and published by CRC Press. This book was released on 2014-08-15 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedic in scope, Reversibility of Chronic Degenerative Disease and Hypersensitivity, Volume 2: The Effects of Environmental Pollutants on the Organ System draws deeply from clinical histories of thousands of patients. It focuses on clinical syndromes within the musculoskeletal, gastrointestinal, and respiratory systems. The book explores mech
Download or read book Blind Spots written by Henrik Isager and published by AuthorHouse. This book was released on 2013-08-30 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: In spite of increasing use of advanced technology, the patient-orientated field of medical science, clinical medicine, has by and large retained the mechanistic-substantial perception of reality inherited from the scientific communities of the eighteenth and nineteenth centuries. In contrast, physics bade farewell to this view more than a century ago and now conceives the world primarily as a dynamic continuum of energy. Biochemists now regard structural (substantially orientated) and dynamic (energetically orientated) aspects of biochemistry as complementary and equally important. As seen from the perspective of the history of ideas, the anachronistic world view of clinical medicine, a view that can be characterised as dogmatic substantialism, places it in an outdated position compared with physics and biochemistry a position from which the existence of biologically relevant energetic phenomena cannot be recognised as such, simply because they are not supposed to exist. During the latest three decades, the epidemic of energy loss, which comprises the diagnostic entities ME/CFS, fibromyalgia, multiple chemical sensitivity, consequences of whiplash injury, and several other conditions, has affected Western societies increasingly and caused significant humanitarian, social, and economical problems. It is no exaggeration to state that the confrontation between conventional clinical medicine and the epidemic of energy loss has created confusion and, all too often, absurdities. Isager attempts a thorough analysis of this situation and its historical and ideological roots, emphasising epistemological problems problems concerned with how we know and how or why we do not know.
Download or read book Endocrine Immunology written by W. Savino and published by Karger Medical and Scientific Publishers. This book was released on 2017-02-28 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decades, several in vitro and in vivo studies have revealed the existence of a very complex network between the neuroendocrine and immune system. Important molecular mechanisms underlying these interactions, in both physiological and pathological conditions, have also been described. Indeed, hormones play a pivotal role in the development and functional regulation of the immune system – both innate and acquired responses. Immune system cells present specific hormone receptors and themselves produce some hormones, thus influencing hormone secretion. More recently, the modulation of hormone secretion has been attempted for treating associated autoimmune disorders, further supporting the strong interplay between the endocrine and immune system. Distinguished experts, who have published extensively in their fields, have contributed comprehensive chapters to this volume. The focus is on the various aspects of endocrine-neuro-immune connections, providing an updated panorama - from basics to clinical applications - of current knowledge and still debated issues.
Book Synopsis Pediatric Chronic Fatigue Syndrome by : Kenny De Meirleir
Download or read book Pediatric Chronic Fatigue Syndrome written by Kenny De Meirleir and published by CRC Press. This book was released on 2007-02-07 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Help young CFS sufferers cope with this debilitating illness Chronic Fatigue Syndrome (CFS) is a debilitating illness that can have devastating effects for those afflicted, especially children and adolescents. Pediatric Chronic Fatigue Syndrome discusses this growing problem and its many facets in depth, including the mounting prevalence of incidents in the population and detailed explanations of diagnostic criteria. Case studies are provided to illustrate the issues those afflicted with CFS face, such as increasing isolation, decreasing school attendance, the length of time it typically takes to get diagnosed, and the impact on leisure activities. Current criteria for CFS were designed for use in adults, with few studies done on assessing how appropriate these criteria are for children and adolescents. Pediatric Chronic Fatigue Syndrome provides the criteria for first-time diagnosis of pediatric CFS and includes practical recommendations developed by the International Association of Chronic Fatigue Syndrome Pediatric Case Definition Working Group. This book closely examines the potential impact that Chronic Fatigue Syndrome has on child and adolescent functioning, psychological factors, social factors, and the suffering endured from symptoms. Guidelines are provided on ways ME-CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) can be addressed in primary practice. Topics in Pediatric Chronic Fatigue Syndrome include: ME/CFS CACFS (Chronic Fatigues Syndrome in Children and Adolescents) the common problem of Munchausen-by-proxy research on the psychosocial, family, and physical functioning comparing children and adolescents with CFS and those without CFS using theory in clinical practice guidelines on how ME/CFS can be addressed in primary practice overview of CFS aspects for healthcare professionals who may be called on to diagnose or treat the illness and more Pediatric Chronic Fatigue Syndrome is timely, important information for health professionals, researchers, counselors, caregivers, parents of children and adolescents with CFS, and patients with CFS.
Book Synopsis Fatigue in Multiple Sclerosis by : Lauren B. Krupp, MD
Download or read book Fatigue in Multiple Sclerosis written by Lauren B. Krupp, MD and published by Demos Medical Publishing. This book was released on 2004-03-01 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical guide for physicians and other health care professionals discusses the impact of fatigue on the individual with MS, the potential etiologies underlying MS-related fatigue, its work up and diagnosis, and pharmacologic and nonpharmacologic management strategies. Fatigue is perhaps the single most prevalent and disabling symptom of the multiple sclerosis, and limits patients' activity more than any other MS symptom. The identification of fatigue as a distinct clinical entity requires both art and science, and most of all, a willingness and ability to listen carefully to patients and their families. The physician's ability to obtain a comprehensive history requires a full understanding of the circumstances in which fatigue occurs (physical, cognitive, and psychosocial) and demands consideration of a large number of disorders, including anxiety, depression, excessive daytime sleepiness, pain, and spasticity, all of which may mimic or contribute to fatigue. While fatigue is almost exclusively a subjective experience, depending on the patient's ability to understand and report this symptom, there are effective methods for identifying the existence of fatigue, determining its severity, and distinguishing it from related or contributing disorders such as depression, pain, and sleep disorders. Readers will learn that fatigue need not be tolerated by the MS patient. Various therapies, support systems, and treatment of underlying affective disorders can all alleviate fatigue or reduce its impact, restoring the patient's energy levels and ability to participate in life. Virtually every MS patient with fatigue can benefit from intervention, and failing to treat the symptom of fatigue with the respect that it deserves is a serious detriment to patient care.
Book Synopsis Clinical Autonomic Dysfunction by : Joseph Colombo
Download or read book Clinical Autonomic Dysfunction written by Joseph Colombo and published by Springer. This book was released on 2014-09-22 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the concepts underlying the measurement of parasympathetic and sympathetic (P&S) activity in the autonomic nervous system and the application of these measurements in the development of therapeutic guidelines for treating dysfunctions in these processes. It provides an overview of the anatomy, physiology, and biochemistry of the autonomic nervous system; details general clinical applications of P&S monitoring that are independent of specialty or disease; presents the pathophysiology of P&S dysfunction in specific disorders, expected test results, therapeutic options, and expected outcomes; and includes case studies and longitudinal studies that demonstrate the major concepts for the common diseases for which P&S monitoring is recommended. Clinical Autonomic Dysfunction enables clinicians to improve patient outcomes by identifying and treating clinical problems related to autonomic nervous system disorders.
Book Synopsis Neuro-Immune Connections to Enable Repair in CNS Disorders by : Tim Vanmierlo
Download or read book Neuro-Immune Connections to Enable Repair in CNS Disorders written by Tim Vanmierlo and published by Frontiers Media SA. This book was released on 2020-10-28 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Book Synopsis Sleep and Quality of Life in Clinical Medicine by : Joris C. Verster
Download or read book Sleep and Quality of Life in Clinical Medicine written by Joris C. Verster and published by Springer Science & Business Media. This book was released on 2008-02-20 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many patients experience sleep disturbances secondary to their primary illness and this often has a negative effect on their quality of life. This book provides an evidence-based introduction to the interface between sleep wide range of medical disorders. A clinically focused, comprehensive review for physicians and other health providers, this state-of-the-art reference can also serve as a textbook for those who wish to become familiar with the impact of sleep on quality of life.
Book Synopsis The Biopsychosocial Model of Health and Disease by : Derek Bolton
Download or read book The Biopsychosocial Model of Health and Disease written by Derek Bolton and published by Springer. This book was released on 2019-03-28 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book is a systematic update of the philosophical and scientific foundations of the biopsychosocial model of health, disease and healthcare. First proposed by George Engel 40 years ago, the Biopsychosocial Model is much cited in healthcare settings worldwide, but has been increasingly criticised for being vague, lacking in content, and in need of reworking in the light of recent developments. The book confronts the rapid changes to psychological science, neuroscience, healthcare, and philosophy that have occurred since the model was first proposed and addresses key issues such as the model’s scientific basis, clinical utility, and philosophical coherence. The authors conceptualise biology and the psychosocial as in the same ontological space, interlinked by systems of communication-based regulatory control which constitute a new kind of causation. These are distinguished from physical and chemical laws, most clearly because they can break down, thus providing the basis for difference between health and disease. This work offers an urgent update to the model’s scientific and philosophical foundations, providing a new and coherent account of causal interactions between the biological, the psychological and social.
Book Synopsis Neuroimmune Interface in Health and Diseases by : Ihssane Zouikr
Download or read book Neuroimmune Interface in Health and Diseases written by Ihssane Zouikr and published by Frontiers Media SA. This book was released on 2017-12-06 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now well appreciated that the immune system, in addition to its traditional role in defending the organism against pathogens, communicate in a well-organized fashion with the brain to maintain homeostasis and regulate a set of neural functions. Perturbation in this brain-immune interactions due to inflammatory responses may lead to psychiatric and neurological disorders. Microglia are one of the essential cells involved in the brain-immune interactions. Microglial cells are now not simply regarded as resident tissue macrophages in the brain. These cells are derived from myeloid progenitor cells in the yolk sac in early gestation, travel to the brain parenchyma and interact actively with neurons during the critical period of neurogenesis. Microglia provide a trophic support to developing neurons and take part in the neural wiring through the activity-dependent synapse elimination via direct neuron-microglia interactions. Altered microglial functions including changes in the gene expression due to early life inflammatory events or psychological and environmental stressors can be causally related to neurodevelopmental diseases and mental health disorders. This type of alterations in the neural functions can occur in the absence of infiltration of inflammatory cells in the brain parenchyma or leptomeninges. In this sense, the pathogenetic state underlying a significant part of psychiatric and neurological diseases may be similar to “para-inflammation”, an intermediate state between homeostatic and classical inflammatory states as defined by Ruslan Medzhitov (Nature 454:428-35, 2008). Therefore, it is important to study how systemic inflammation affects brain health and how local peripheral inflammation induces changes in the brain microenvironment. Chronic pain is also induced by disturbance in otherwise well-organized multisystem interplay comprising of reciprocal neural, endocrine and immune interactions. Especially, early-life insults including exposure to immune challenges can alter the neuroanatomical components of nociception, which induces altered pain response later in life. Recently the discrete roles of microglia and blood monocyte-derived macrophages are being defined. The distinction may be further highlighted by disorders in which the brain parenchymal tissue is damaged. Therefore, studies investigating the dynamics of immune cells in traumatic brain injury and neurotropic viral infections including human immunodeficiency virus, etc. as well as neurodegenerative diseases such as amyotrophic lateral sclerosis are promising to clarify the interplay between the central nervous and immune systems. The understanding of the histological architecture providing the infrastructure of such neuro-immune interplay is also essential. This Frontiers research topic brings together fourteen articles and aims to create a platform for researchers in the field of psychoneuroimmunology to share the recent theories, hypotheses and future perspectives regarding open questions on the mechanisms of cell-cell interactions with chemical mediators among the nervous, immune and endocrine systems. We hope that this platform would reveal the relevance of the studies on multisystem interactions to enhance the understanding of the mechanisms underlying a wide variety of neurological and psychiatric disorders.
Book Synopsis Neuroimmune Pharmacology by : Tsuneya Ikezu
Download or read book Neuroimmune Pharmacology written by Tsuneya Ikezu and published by Springer Science & Business Media. This book was released on 2008-03-21 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroimmune pharmacology seeks to harness the immune system to provide pharmacological intervention to combat neurodegenerative diseases. This book provides a comprehensive overview of topics that embrace the link between the immune system and the pathogenesis of neurodegenerative disorders. Results from recent studies strongly suggest that a major part of the process in diseases including Alzheimer’s and Parkinson’s as well as Prion diseases, comes from changes in the innate and adaptive arms of the brain and peripheral immune systems. Thus, the book provides an in-depth study of numerous fields including immunology, pharmacology, neuroscience and neurovirology. It is accompanied by a CD-ROM that includes access to lectures, slide presentations, and question and answers on neuroimmune pharmacology.
