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Author : Amteshwar Singh Jaggi
Publisher :
ISBN 13 : 9789389974348
Total Pages : 384 pages
Book Rating : 4.9/5 (743 download)
Download or read book Cellular and Molecular Pharmacology written by Amteshwar Singh Jaggi and published by . This book was released on 2021-02 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Stefan Offermanns
Publisher : Springer Science & Business Media
ISBN 13 : 3540389164
Total Pages : 1515 pages
Book Rating : 4.5/5 (43 download)
Download or read book Encyclopedia of Molecular Pharmacology written by Stefan Offermanns and published by Springer Science & Business Media. This book was released on 2008-08-14 with total page 1515 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.
Author : Francesco Clementi
Publisher : John Wiley & Sons
ISBN 13 : 1118768590
Total Pages : 784 pages
Book Rating : 4.1/5 (187 download)
Download or read book General and Molecular Pharmacology written by Francesco Clementi and published by John Wiley & Sons. This book was released on 2015-07-01 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use- without neglecting clinical application, toxicology and pharmacokinetics. • Covers cell and molecular pharmacology, bringing together current research on regulation of drug targets, at a level appropriate for advanced undergrad and graduate students • Discusses the relevance of pharmacokinetics and drug development for the clinical application of drugs • Presents material from the perspective of drug targets and interaction, the theoretical basis of drug action analysis, and drug properties • Focuses on structure-function relationships of drug targets – informing about their biochemical and physiologic functions and experimental and clinical pathways for drug discovery and development • Has a companion website that offers a host of resources: short additional chapters about methodology, topics at the forefront of research, and all figures and tables from the book
Author : Dr. Niraj. S. Vyawahare
Publisher : Walnut Publication
ISBN 13 : 9355741197
Total Pages : 123 pages
Book Rating : 4.3/5 (557 download)
Download or read book Experimental Aspects of Cellular and Molecular Pharmacology: A Treatise written by Dr. Niraj. S. Vyawahare and published by Walnut Publication. This book was released on 2021-12-16 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding interaction between drug molecules and targets is a major pharmacological skill. Molecular and Cellular Pharmacology approaches have greatly increased the knowledge of the structure and function of drug targets, such as receptors, enzymes and transport molecules, revealing diversity far greater than had been realised. This textbook provides a comprehensive and accessible introduction to the rapidly expanding field of cellular and molecular pharmacology. The book deals with most commonly used experiments to understand the relationship of proteins and their involvement in a pathological state at molecular and cellular level. This book is off immense use for research scholars dealing with protein estimation and identification.
Author : John Dickenson
Publisher : John Wiley & Sons
ISBN 13 : 1118451953
Total Pages : 675 pages
Book Rating : 4.1/5 (184 download)
Download or read book Molecular Pharmacology written by John Dickenson and published by John Wiley & Sons. This book was released on 2012-11-30 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of ‘trial and error’ drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments. Providing an invaluable resource for advanced under-graduate and MSc/PhD students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy, pharmacogenomics and looks at the role of calcium in the cell. Current - focuses on cutting edge techniques and approaches, including new methods to quantify biological activities in different systems and ways to interpret and understand pharmacological data. Cutting Edge - highlights advances in pharmacogenomics and explores how an individual’s genetic makeup influences their response to therapeutic drugs and the potential for harmful side effects. Applied - includes numerous, real-world examples and a detailed case-study based chapter which looks at current and possible future treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect. Accessible - contains a comprehensive glossary, suggestions for further reading at the end of each chapter and an associated website that provides a complete set of figures from within the book.
Author : Francesco Clementi
Publisher : John Wiley & Sons
ISBN 13 : 1118768574
Total Pages : 784 pages
Book Rating : 4.1/5 (187 download)
Download or read book General and Molecular Pharmacology written by Francesco Clementi and published by John Wiley & Sons. This book was released on 2015-08-10 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use- without neglecting clinical application, toxicology and pharmacokinetics. • Covers cell and molecular pharmacology, bringing together current research on regulation of drug targets, at a level appropriate for advanced undergrad and graduate students • Discusses the relevance of pharmacokinetics and drug development for the clinical application of drugs • Presents material from the perspective of drug targets and interaction, the theoretical basis of drug action analysis, and drug properties • Focuses on structure-function relationships of drug targets – informing about their biochemical and physiologic functions and experimental and clinical pathways for drug discovery and development • Has a companion website that offers a host of resources: short additional chapters about methodology, topics at the forefront of research, and all figures and tables from the book
Author : Ms. Manisha Chhikara
Publisher : JEC PUBLICATION
ISBN 13 : 9358503262
Total Pages : 256 pages
Book Rating : 4.3/5 (585 download)
Download or read book CELLULAR AND MOLECULAR PHARMACOLOGY written by Ms. Manisha Chhikara and published by JEC PUBLICATION. This book was released on with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: .....
Author : Edward Bittar
Publisher : Elsevier
ISBN 13 : 008053676X
Total Pages : 419 pages
Book Rating : 4.0/5 (85 download)
Download or read book Molecular and Cellular Pharmacology written by Edward Bittar and published by Elsevier. This book was released on 1997-11-24 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular and Cellular Pharmacology
Author : Bryan L. Roth
Publisher : Springer Science & Business Media
ISBN 13 : 1597450804
Total Pages : 628 pages
Book Rating : 4.5/5 (974 download)
Download or read book The Serotonin Receptors written by Bryan L. Roth and published by Springer Science & Business Media. This book was released on 2008-08-17 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for drug discovery. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction.
Author : MS S
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.8/5 (897 download)
Download or read book Cellular and Molecular Pharmacology written by MS S and published by . This book was released on 2023-02-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell and molecular pharmacology is a branch of pharmacology that deals with the study of drugs and their interactions with cells and molecules at a cellular and molecular level. Cell signaling refers to the process by which cells communicate with each other and respond to changes in their environment. It involves the transfer of signals or messages from outside a cell to the inside of a cell and the subsequent response by the cell. The signaling process is initiated by the binding of signaling molecules (such as hormones, growth factors, or neurotransmitters) to specific receptors on the cell surface. Cell signaling plays a crucial role in many physiological processes, such as development, homeostasis, immune response, and communication between cells. Molecular tools refer to techniques and methods used in molecular biology and biochemistry to study biological molecules and their interactions. Some common molecular tools used in cell and molecular pharmacology are: Recombinant DNA technology, Polymerase chain reaction (PCR), Gel electrophoresis, Mass spectrometry, X-ray crystallography, Fluorescence microscopy, Microarray Cell culture techniques refer to methods used to grow and maintain cells in the laboratory. Cell culture is a critical tool in cell and molecular pharmacology as it allows researchers to study the behavior of cells outside of the body, and to examine the effects of drugs and other substances on cells.
Author : Stefan Offermanns
Publisher :
ISBN 13 :
Total Pages : 1152 pages
Book Rating : 4.3/5 (91 download)
Download or read book Encyclopedic Reference of Molecular Pharmacology written by Stefan Offermanns and published by . This book was released on 2004 with total page 1152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents current information on the molecular mechanisms of drug action. Provides 159 essays describing groups of drugs and drug targets. Several essays deal with general principles of pharmacology, such as drug tolerance, drug addiction, or drug metabolism.
Download or read book Department of Cellular and Molecular Pharmacology, University of California at San Francisco written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Features the Department of Cellular and Molecular Pharmacology of the University of California at San Francisco. Posts contact information via mailing address, telephone and fax numbers, and e-mail. Lists the faculty members. Discusses the department research, professional teaching programs, graduate programs, the curricula, and funding opportunities.
Author : H. Glossmann
Publisher : Springer Science & Business Media
ISBN 13 : 1475722397
Total Pages : 278 pages
Book Rating : 4.4/5 (757 download)
Download or read book Methods in Pharmacology written by H. Glossmann and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The current volume provides detailed experimental protocols used to study plasma membrane ion channels as pharmacological targets. Coverage includes molecular and biochemical characterization of ion channels; fuctional analysis of ion channels after reconstitution, expression, or in cells; and specific methods and tools. This wealth of information will benefit academic and industrial researchers and graduate students in pharmacology, biochemistry, physiology, and biophysics.
Author : Pier Andrea Borea
Publisher : Springer Science & Business Media
ISBN 13 : 9048131448
Total Pages : 324 pages
Book Rating : 4.0/5 (481 download)
Download or read book A3 Adenosine Receptors from Cell Biology to Pharmacology and Therapeutics written by Pier Andrea Borea and published by Springer Science & Business Media. This book was released on 2009-12-01 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, with its 16 chapters, documents the present state of knowledge of the adenosine A receptor. It covers a wide range of information, including data from 3 studies of theoretical, molecular and cellular pharmacology, signal transduction, integrative physiology, new drug discoveries and clinical applications. It fills an important gap in the literature since no alternative source of such information is currently available. Although the A receptor is increasingly being recognized for 3 its increasing number of biological roles throughout the body and many A receptor 3 ligands have proven useful in elucidating peripheral and central pathologies, many issues remain unresolved. Moreover, research activity in this field continues to grow exponentially, resulting in a constant flow of new information. The chapters in this book cover both basic science and the relevant applications and provide an authoritative account of the current status of the field. They have enabled my goal as editor to make “A Adenosine Receptors from Cell Biology to Pharmacology and 3 Therapeutics” an up to date, scientifically excellent, reference source, attractive to basic and clinical scientists alike, a reality. Detailed understanding of the physico-chemical aspects and molecular biology of the A receptor provides a solid basis for its future development as a target for 3 adenosine-based pharmacotherapies (Chapters 2 and 3).
Author : University of Virginia
Publisher :
ISBN 13 :
Total Pages : 32 pages
Book Rating : 4.:/5 (137 download)
Download or read book Cellular & Molecular Pharmacology at the University of Virginia written by University of Virginia and published by . This book was released on 1994 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Georges Vauquelin
Publisher : John Wiley & Sons
ISBN 13 : 9780470516645
Total Pages : 264 pages
Book Rating : 4.5/5 (166 download)
Download or read book G Protein-coupled Receptors written by Georges Vauquelin and published by John Wiley & Sons. This book was released on 2008-03-11 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: G protein-coupled receptors (GPCRs) are membrane proteins that transduce a vast array of extracellular signals into intracellular reactions ranging from cell-cell communication processes to physiological responses. They play an important role in a variety of diseases from cancer and diabetes, to neurodegenerative, inflammatory and respiratory disorders. GPCRs are therefore of utmost interest in drug development: over half of all prescription drugs currently on the market act by targeting these receptors directly or indirectly. G Protein-coupled Receptors: Molecular Pharmacology provides a clear summary of the current knowledge in this fast-evolving field. The book sets out with an introduction to signalling molecules and their receptors, and an overview of the technical approaches used to investigate these interactions. Structural, functional and especially pharmacological aspects of GPCRs are then discussed in more detail and much attention is devoted to the analysis and interpretation of experimental data. The now widespread use of recombinant cell lies, receptor mutants and related artifices in drug research is critically evaluated. Special attention is also devoted to topical but often poorly understood concepts, such as insurmountable antagonism, inverse agonism and allosteric interactions. By combining general information with the major state-of-the-art concepts in GPCR-research, this outstanding book equips the reader with the necessary background for understanding and critically evaluating the current literature. Written by two experts from academia and industry, G Protein-coupled Receptors: Molecular Pharmacology offers a unique view of academic and applied approaches aiming to reveal new ideas in pharmaceutical research. The book is of interest to anyone involved in drug development and preclinical research and those who need to function within multi-disciplinary teams in the pharmaceutical industry: from investigators to product managers or clinicians who seek to have a broad mechanistic understanding of drug-receptor interactions. It is also an invaluable resource for final year undergraduate and postgraduate students in pharmacology and cell and molecular biology.
Author : George Poste
Publisher : Springer
ISBN 13 : 9781468454895
Total Pages : 496 pages
Book Rating : 4.4/5 (548 download)
Download or read book Cellular and Molecular Aspects of Inflammation written by George Poste and published by Springer. This book was released on 2012-03-26 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: The characterization of the cellular and molecular mechanisms that mediate inflammation provides a foundation that supports future studies that will de fine mechanisms more intimately. It encourages substantial optimism about the opportunities to understand the inflammatory process and to use that information to develop novel therapeutic approaches. Recent progress has defined the cells that mediate the inflammatory response, many of the inter cellular transmitters, the receptors, signal transduction processes and regula tory mechanisms. Thus, we now have the opportunity to understand inflammation in pharmacologic terms and to attack the key molecular targets to develop new therapeutics. Among the cells involved in the inflammatory response are the lympho cytes, neutrophils and endothelial cells. Maintenance of homeostasis, re sponse to proinflammatory stimuli and pathophysiologic responses are products of complex interactions between these and other elements of the immune systems. Each of these cells displays a variety of receptors to define the stimuli to which they respond. The receptors displayed that the signal transduction processes and cellular responses are regulated genetically and epigenetic ally . The critical role of membranes and particularly the phospho lipid components of the membranes is emphasized by recent studies.
