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Cardiac Adaptation In Heart Failure
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Book Synopsis Cardiac Adaptation in Heart Failure by : J. Holtz
Download or read book Cardiac Adaptation in Heart Failure written by J. Holtz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, cardiac hypertrophy is regarded as an adaptation of the heart to permanent mechanical overload. Regardless of the fact that many different and often unknown primary causes can result in heart failure, mechanical overload and myocardial hypertrophy is found in almost all forms of manifest chronic heart failure (apart from failure due to extramyocardial hindrances to inflow or to relaxation). However, the reactive enlargement of myocardial mass in response to an enhanced hemodynamic burden appears to be a double-edged sword. Obviously, the hypertrophy helps to reduce the enhanced ventricular wall stress in heart failure by adding contractile units to the overdistended chamber wall. However, in recent years it became clear that this adaptive hypertrophic process is rather complex and may include problematic facets. The adaptive hypertrophy includes proliferation of the nonmyocyte cardiac cells as well as substantial alterations in the phenotype of the growing myocytes due to differential changes in gene expression.
Book Synopsis Cardiac Adaptation and Failure by : Masatsugu Hori
Download or read book Cardiac Adaptation and Failure written by Masatsugu Hori and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in cellular physiology and molecular biology have now disclosed the metabolic changes and adaptational responses of the heart to various kinds of stresses. Topics covered in this volume include the regulation of myocardial proteins in mechanical overload, the alteration of adrenoceptors in the stressed heart, metabolic adaptation in cardiac hypertrophy, intracellular calcium metabolism in the ischemia-reperfused myocardium, calcium overload as a cause of myocardial stunning, acquisition of ischemic tolerance by ischemic preconditioning, factors that accelerate myocardial injury, and ventricular remodeling in the ischemic heart. As an update of the latest findings in basic cardiology, this book will benefit both researchers and clinical practitioners.
Book Synopsis Cardiac Adaptation in Heart Failure by : J. Holtz
Download or read book Cardiac Adaptation in Heart Failure written by J. Holtz and published by Steinkopff. This book was released on 1993-02-12 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditionally, cardiac hypertrophy is regarded as an adaptation of the heart to permanent mechanical overload. Regardless of the fact that many different and often unknown primary causes can result in heart failure, mechanical overload and myocardial hypertrophy is found in almost all forms of manifest chronic heart failure (apart from failure due to extramyocardial hindrances to inflow or to relaxation). However, the reactive enlargement of myocardial mass in response to an enhanced hemodynamic burden appears to be a double-edged sword. Obviously, the hypertrophy helps to reduce the enhanced ventricular wall stress in heart failure by adding contractile units to the overdistended chamber wall. However, in recent years it became clear that this adaptive hypertrophic process is rather complex and may include problematic facets. The adaptive hypertrophy includes proliferation of the nonmyocyte cardiac cells as well as substantial alterations in the phenotype of the growing myocytes due to differential changes in gene expression.
Book Synopsis Cardiac Adaptations by : Bohuslav Ostadal
Download or read book Cardiac Adaptations written by Bohuslav Ostadal and published by Springer Science & Business Media. This book was released on 2012-10-12 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes present knowledge of different mechanisms involved in the development of positive and negative consequences of cardiac adaptation. Particular attention is paid to the still underestimated adaptive cardiac responses during development, to adaptation to the frequently occurring pressure and volume overload as well as to cardiac changes, induced by enduring exercise and chronic hypoxia. Cardiac Adaptations will be of great value to cardiovascular investigators, who will find this book highly useful in their cardiovascular studies for finding solutions in diverse pathological conditions; it will also appeal to students, fellows, scientists, and clinicians interested in cardiovascular abnormalities.
Book Synopsis Acute Heart Failure by : Alexandre Mebazaa
Download or read book Acute Heart Failure written by Alexandre Mebazaa and published by Springer Science & Business Media. This book was released on 2009-12-24 with total page 922 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, there has been a great deal of work done on chronic congestive heart failure while acute heart failure has been considered a difficult to handle and hopeless syndrome. However, in recent years acute heart failure has become a growing area of study and this is the first book to cover extensively the diagnosis and management of this complex condition. The book reflects the considerable amounts of new data reported and many new concepts which have been proposed in the last 3-4 years looking at the epidemiology, diagnostic and treatment of acute heart failure.
Book Synopsis Cardiac Adaptation to Hemodynamic Overload, Training and Stress by : R. Jacob
Download or read book Cardiac Adaptation to Hemodynamic Overload, Training and Stress written by R. Jacob and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac hypertrophy and accompanying phenomena have received increasing attention in recent years - particularly in the basic sciences. The present volume contains the proceedings of the Erwin RIESCH SYMPOSIUM on "CARDIAC ADAPTATION TO HEMODYNAMIC OVERLOAD, TRAINING AND STRESS" held in Tiibingen on Sep tember 19-22, 1982. In addition to the topics of the previous symposia (1976 and 1979) concerned with problems of cardiac hypertrophy, the scope of this sequel meeting has been expanded to include related fields. The intention was to consider numerous related features and problems of chronic reactions of the heart (and vascular system) to abnormal hemodynamic loading, as well as alterations due to maturation, aging, training, neuroendocrine status and stress. Special attention has been paid to cardiac reactions at the level of contractile proteins. The results are considered primarily in light of long-term adaptation of the heart. Of course, research at the forefront of current knowledge need not always lead to congruent conclusions. Neither can the individual contributions always agree with the viewpoint of the editors. However, the broad array of individual approaches employed by biochemists, biolo gists, pathologists, physiologists, pharmacologists and clinical cardio logists will certainly help to provide a more balanced interpretation of the results in individual fields, stimulate reexamination of established con cepts and provide direction for future research.
Book Synopsis Cardiac Remodeling: New Insights in Physiological and Pathological Adaptations by : Leonardo Roever
Download or read book Cardiac Remodeling: New Insights in Physiological and Pathological Adaptations written by Leonardo Roever and published by Frontiers Media SA. This book was released on 2017-11-15 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: The effective management of Cardiac remodeling(CR), remains a major challenge. Heart failure remains the leading cause of death in industrialized countries. Yet, despite the enormity of the problem, effective therapeutic interventions remain elusive. In fact, several initially promising agents were found to decrease mortality in patients recovering from myocardial infarction. Cardiac remodeling is defined as molecular and interstitial changes, manifested clinically by changes in size, mass , geometry and function of the heart in response to certain aggression. Initially, ventricular remodeling aims to maintain stable cardiac function in situations of aggression.
Author :Pavel Hála Publisher :Charles University in Prague, Karolinum Press ISBN 13 :8024648989 Total Pages :94 pages Book Rating :4.0/5 (246 download)
Book Synopsis Hemodynamic Adaptation Mechanisms of Heart Failure to Percutaneous Venoarterial Extracorporeal Circulatory Support by : Pavel Hála
Download or read book Hemodynamic Adaptation Mechanisms of Heart Failure to Percutaneous Venoarterial Extracorporeal Circulatory Support written by Pavel Hála and published by Charles University in Prague, Karolinum Press. This book was released on 2022-01-01 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monograph focusing on effects of extracorporeal circulatory supports on systemic hemodynamics and left ventricular work. The author summarizes history, applications, and consequences of the venoarterial circulatory supports in patients with decompensated heart failure. The text also includes results from original experimental work on biomodels of acute and chronic heart failure and their correlation with current physiological views.
Book Synopsis Cardiac Adaptation and Failure by : Masatsugu Hori
Download or read book Cardiac Adaptation and Failure written by Masatsugu Hori and published by . This book was released on 1994 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cardiac Adaptation in Heart Failure by :
Download or read book Cardiac Adaptation in Heart Failure written by and published by . This book was released on 1992 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cardiac Remodeling and Failure by : Pawan K. Singal
Download or read book Cardiac Remodeling and Failure written by Pawan K. Singal and published by Springer Science & Business Media. This book was released on 2003-02-28 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of the developmental approach for experimental and clinical cardiology is indisputable. Clinical-epidemiological studies have clearly shown that the risk factors of serious cardiovascular diseases, such as atherosclerosis and ischemic heart disease, are already present during the early phases of ontogenetic development. Furthermore, congenital cardiovascular malformations remain the single largest cause of infant mortality from congenital defects in industrial countries. It is therefore not surprising that the interest of theoretical and clinical cardiologists in the developmental approach keeps increasing. Advances in molecular biology accelerated this trend substantially. This book is based on contributions presented at the international symposium The Developing Heart in Prague in May 2000. It is our contention that the biological, electrophysiological, morphological, functional, biochemical and functional approaches employed by distinguished scientists worldwide will provide the reader with a global picture for changes characterizing the developing heart. It should stimulate the curiosity of cardiovascular scientists in gaining insight into the mechanisms of normal and pathological development.
Book Synopsis Heart Metabolism in Failure by : R.A. Altschuld
Download or read book Heart Metabolism in Failure written by R.A. Altschuld and published by Elsevier. This book was released on 1998-09-21 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart failure continues to be a major public health problem in the United States with close to half a million new cases diagnosed each year. Moreover, deaths from heart failure are on the increase, in part because of advances in the treatment of other fatal diseases, and in part from the prevalence of lifestyles indifferent to the risk factors for heart disease. This is not to say that no progress has been made in the treatment of heart failure. While for many years treatment was confined to the management of the symptoms, in recent years with the advent of ACE inhibitor and ß blacker therapies, real improvements in cardiac function and life expectancy have been achieved (Volume 4B, Leier). On a more basic level, enormous advances have been made in describing many of the changes in structure and function of the heart and the parallel neurohumoral and circulatory adaptations that occur during the onset of failure. These advances have been made not only by using various animal models of heart failure, but also using fresh failing human heart tissue, which has become readily available for experimental investigation since the advent of cardiac transplantation.Understanding the significance of many of these changes that occur during the transition to failure and the role they play in the etiology of failure is, however, a much more difficult task. These are exciting times in heart failure research. It is as though many of the pieces of the jigsaw puzzle are available but the puzzle has yet to be assembled. The objective of these volumes is to bring together some advances that have been made in recent years in defining one aspect of the failing heart, that is, the role of altered metabolism, in order to facilitate assembly of the puzzle.
Download or read book Heart Failure written by Arnold M. Katz and published by Lippincott Williams & Wilkins. This book was released on 2012-11-07 with total page 737 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Second Edition of Dr. Katz's highly acclaimed text has been thoroughly revised to incorporate the latest advances in the study and treatment of heart failure. The book explains the pathophysiology, molecular mechanisms, clinical manifestations, and therapy of heart failure in an integrated, reader-friendly manner that is accessible to both clinicians and basic scientists. More than 100 illustrations, most created for this book by the authors, complement the text. This edition has been completely reorganized. Chapters describe the hemodynamic basis for the clinical manifestations of heart failure; the neurohumoral responses in heart failure and key signaling pathways that mediate functional responses; the proliferative responses in failing hearts; the cellular and molecular abnormalities in the failing heart; the rationale for various therapeutic approaches; and the management of specific groups of patients. The chapters on therapy have been written by a noted clinician, Marvin A. Konstam.
Book Synopsis 4 Stages of Heart Failure, The by : Brian E. Jaski, MD, FACC
Download or read book 4 Stages of Heart Failure, The written by Brian E. Jaski, MD, FACC and published by Cardiotext Publishing. This book was released on 2015-03-02 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: If you understand heart failure, you understand cardiology This book applies practical clinical concepts to the latest four-stage model of heart failure from preclinical risk and early asymptomatic disease to classic symptomatic heart failure and finally advanced heart failure. This framework emphasizes a tailored approach to ongoing heart failure assessment to guide therapy and improve outcomes. Features: Illustrated with over 250 full-color figuresSpecific recommendations backed by clinical trial dataPractical algorithms for diagnosis and therapy Topics include: Prevention of heart failureIdentification and treatment of structural heart disease prior to heart failureHow to combine lifestyle changes, medications, and devices to improve outcomesReversing decompensated heart failureKey indicators of advanced heart failure and appropriate treatment optionsEmerging new therapies “This book will be valuable to all training and practicing clinicians. He writes as if you and he are both completing patient rounds together. Brian E. Jaski is to be commended for capturing the essence of treating this formidable clinical challenge and demystifying the stages of heart failure.” --From the foreword by Sidney C. Smith, Jr. MD FACC, FAHA, FESC, FACP Professor of Medicine, University of North Carolina at Chapel Hill Past President, American Heart Association Past President, World Heart Federation “The culmination of Dr. Jaski’s 25 years of teaching experience and clinical acumen is now available in one highly readable text designed to highlight key information and stimulate the learning process.” --Dylan E. Wessman, MD, FACC, FACP Program Director, Cardiovascular Disease Fellowship Naval Medical Center San Diego San Diego, California
Book Synopsis From Hypertension to Heart Failure by : Michael Böhm
Download or read book From Hypertension to Heart Failure written by Michael Böhm and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arterial hypertension, coronary heart disease and heart fail ure are the commonest cardiovascular conditions to present in clinical practice. Over the past few years it has become in creasingly clear that they are closely and causally interrelated and that their relationship can have a significant bearing on prognosis. Epidemiological studies have shown that arterial hypertension is one of the most important risk factors for de veloping heart failure. Only one in four patients with hyper tension is adequately managed, and in 50% of cases, the hypertension has not been recognised or treated. Patients with pre-existing hypertension who go on to suffer an acute myocardial infarction have usually not previously had typi cal angina symptoms, the infarct territory is larger, life threatening arrhythmias are commoner and hence in-hospi tal mortality and long-term prognosis are markedly worse. The presence of raised blood pressure in the post-infarct phase doubles the risk of manifest heart failure. The close relationship between hypertension, coronary heart disease and heart failure makes the choice of therapeu tic strategy particularly important. Agents and classes of agents that have prognostic value in all three conditions should be considered first, as synergy might result in addi tional benefits. In such patients, this sort of therapeutic deci sion-making might have further advantages. The use of these agents may prevent complications which are not yet clinically obvious (such as heart failure).
Book Synopsis Dilated Cardiomyopathy by : Gianfranco Sinagra
Download or read book Dilated Cardiomyopathy written by Gianfranco Sinagra and published by Springer. This book was released on 2019-05-17 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease’s pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment interaction. The second part presents current and future treatment options, highlighting the importance of long-term and individualized treatments and follow-up. Furthermore, it discusses open issues, such as the apparent healing phenomenon, the early prognosis of arrhythmic events or the use of genetic testing in clinical practice. Offering a multidisciplinary approach for optimizing the clinical management of DCM, this book is an invaluable aid not only for the clinical cardiologists, but for all physicians involved in the care of this challenging disease.
Book Synopsis Right Ventricular Physiology, Adaptation and Failure in Congenital and Acquired Heart Disease by : Mark K. Friedberg
Download or read book Right Ventricular Physiology, Adaptation and Failure in Congenital and Acquired Heart Disease written by Mark K. Friedberg and published by Springer. This book was released on 2017-12-19 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book spans topics in both congenital and acquired right heart disease providing readers with detailed information on the physiology, anatomy and myocardial mechanics of the right ventricle (RV), while describing the use of echo and MRI imaging to diagnose, and new developments in surgery and cardiac catheterization to treat. Right Ventricular Physiology, Adaptation and Failure in Congenital and Acquired Heart Disease includes extensive discussion of RV-pulmonary interactions, pulmonary hypertension and ventricular-ventricular interactions, including specific topics in embryology, fetal RV function, RV mechanics, pathophysiology of RV adaptation/ failure, molecular aspects of RV dysfunction, congenital heart disease, pulmonary arterial hypertension, pulmonary valve replacement, stem cell and future therapies. It is thus important reading for all cardiovascular medicine professionals, but especially pediatric cardiologists and surgeons, those who manage t hese patients in the cardiac care unit and investigators studying the RV.
