Carbohydrate Chemistry in the Total Synthesis of Naturally Occurring Glycosides

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Publisher : John Wiley & Sons
ISBN 13 : 3527817905
Total Pages : 309 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Carbohydrate Chemistry in the Total Synthesis of Naturally Occurring Glycosides by : Biao Yu

Download or read book Carbohydrate Chemistry in the Total Synthesis of Naturally Occurring Glycosides written by Biao Yu and published by John Wiley & Sons. This book was released on 2024-03-20 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate Chemistry in the Total Synthesis of Naturally Occurring Glycosides Revolutionize your manufacturing processes and more with this groundbreaking introduction Carbohydrates and complex glycosides are important classes of molecules. The ubiquitous glycosides are extremely diverse in structure and functions, and many of them are of pharmacological significance. Purification of a homogeneous glycoside from the nature sources, especially in an appreciable amount, is always difficult. Chemical synthesis provides a feasible access to the homogenous glycosides and their congeners. Carbohydrate Chemistry in the Total Synthesis of Naturally Occurring Glycosides presents about 10 families of naturally occurring glycoside natural products, including about 150 molecules that organic chemists have devoted a lot of effort toward their synthesis. In each example, the background of each natural glycoside, including its natural resources, its isolation process and its bioactivities have been described; the total synthesis of the natural glycoside is presented with special emphasis on the glycosylation reaction, the strategy on saccharides assembly, the protecting group manipulation, and the method for the synthesis of the rare saccharide units. Readers can clearly see the progress of total synthesis of naturally occurring glycosides, from early to current arts, from simple to complex molecules, and from tedious strategy to highly efficient and economical methodologies in this book. It will highly benefit the further developments in the total synthesis of naturally occurring glycosides and synthetic carbohydrate chemistry. Carbohydrate Chemistry in the Total Synthesis of Naturally Occurring Glycosides is ideal for Organic Chemists, Biochemists, Pharmaceutical and Medicinal Chemists, Natural Products Chemists, and Pharmaceutical Industry

Synthetic Strategies in Carbohydrate Chemistry

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Author :
Publisher : Elsevier
ISBN 13 : 0323986498
Total Pages : 775 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Synthetic Strategies in Carbohydrate Chemistry by : Vinod Kumar Tiwari

Download or read book Synthetic Strategies in Carbohydrate Chemistry written by Vinod Kumar Tiwari and published by Elsevier. This book was released on 2023-11-01 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Strategies in Carbohydrate Chemistry covers carbohydrate synthesis and its widespread application in various disciplines including catalysis. Basic and advanced aspects of carbohydrates are covered, starting with a brief introduction and then followed by protection-deprotection strategies in carbohydrate chemistry, glycosidic bond formation methodology, and their impact in oligosaccharide synthesis. Recent synthetic approaches for O-glycosides, N-glycosides, thioglycosides and C-glycosides, Intramolecular Aglycon Delivery (IAD), and carbohydrate modification are discussed, as well as stereoelectronic factors that control the chemical and biochemical behavior of carbohydrates in living cells. In addition, diverse applications of synthetic carbohydrate chemistry are covered, including sugar-based chiral catalyst in stereoselective synthesis, sugar-based ionic liquids, one-pot tandem reactions in carbohydrates, total synthesis of glycoconjugated natural products, impact of sugar in drug discovery and development, vaccine development, and glycoengineering. This reference is essential reading for researchers working in synthetic carbohydrate chemistry and biochemistry, and will be useful to those working in total synthesis, novel synthetic methodology, catalysis, polymer science, glycobiology, medicinal chemistry, and process development chemistry. Presents a practical and detailed overview on glycosylation methodology Covers automated glycosylation strategies in glycan synthesis Includes recent progress in the synthesis and significance of diverse thio-glycosides, C-glycosides, imino sugars and carbasugars Highlights the impact of enzymes in glycan synthesis Discusses the recent approaches for the synthesis of neoglycoconjugates

Naturally Occurring Glycosides

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Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 472 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Naturally Occurring Glycosides by : Raphael Ikan

Download or read book Naturally Occurring Glycosides written by Raphael Ikan and published by John Wiley & Sons. This book was released on 1999-03-12 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Naturally Occurring Glycosides Edited by Raphael Ikan The Hebrew University of Jerusalem, Israel Naturally Occurring Glycosides summarises significant contemporary information on chemical, nutritional, biological and pharmacological aspects of naturally occurring glycosides. Though mainly found in plants, there are an overwhelming number of glycosides which occur in nature. Currently at the forefront of scientific investigation, these compounds have a variety of uses including the treatment of congestive heart failure, lowering cholesterol, flavourings, antibiotics and sweeteners. Naturally Occurring Glycosides presents 12 chapters dealing with chemical structure, occurrence, biosynthetic and biological activity of the following: Aminoglycosidic antibiotics; Anthocyanin glycosides; Cardiac glycosides; Carotenoid glycosides; Cyanogenic glycosides; Glycosinolates; Glycosidic bound volatiles in plants; Limonoid glycosides; Saponins; Steroidal glycoalkaloids; Steroidal oligosaccarides from marine sources; Terpenoid glycoside sweeteners. By reading Naturally Occurring Glycosides, researchers working in chemistry, biochemistry, biology, toxicology, physiology and pharmacology will gain a fascinating insight into the field of glycosides.

Synthesis and Characterization of Glycosides

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Publisher : Springer Science & Business Media
ISBN 13 : 0387262512
Total Pages : 362 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Synthesis and Characterization of Glycosides by : Marco Brito Arias

Download or read book Synthesis and Characterization of Glycosides written by Marco Brito Arias and published by Springer Science & Business Media. This book was released on 2006-12-12 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the best known approaches for preparing the main types of glycosides in a short and comprehensive study. It also includes synthetic pathways of challenging glycosides known as antiviral or antineoplasic drugs, or synthetic substrates used for enzymatic detection including those used as substrates for detection of gene markers in plant biotechnology. Special attention is made on the structural characterization, providing the basic tools for the structural assignment through NMR, X-Ray and mass spectra techniques. Some of the chapters cover strategies for preparation of antiviral and antineoplasic drugs included in a drug design course.

Modern Methods in Carbohydrate Synthesis

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Publisher : CRC Press
ISBN 13 : 1000124665
Total Pages : 577 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Modern Methods in Carbohydrate Synthesis by : Shaheer H. Khan

Download or read book Modern Methods in Carbohydrate Synthesis written by Shaheer H. Khan and published by CRC Press. This book was released on 2020-08-26 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Methods in Carbohydrate Synthesis presents in one volume a sequence of chapters leading from classical methods through to today's newest state-of -the-art technology for oligosaccharide synthesis. It places particular emphasis on the most recent breakthroughs in the field, including emerging technologies for both oligosaccharide and glycoconjugate synthesis. Chapters describing the synthesis of increasingly important glycosidic linkage analogs, as well as the oligosaccharides containing derivatives and analogs of natural sugars are included. While chemical-synthetic methods constitute the major part of the book, completing the volume is a section on the rapidly expanding and important field of enzymatic synthesis, also covering combined chemical and enzymatic synthesis. Chapters are written by leading experts in the field. Wherever possible, methods of synthesis are provided in sufficient detail to allow the reader to implement the techniques described. More than 1700 references are provided in the 21 chapters comprising the book. This volume should provide a wealth of information to a large number of synthetic organic chemists, medicinal chemists, protein chemists, biochemists, glycobiologists and cell biologists, including students in these fields.

Modern Organocatalyzed Methods in Carbohydrate Chemistry

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Publisher : Springer
ISBN 13 : 3319175939
Total Pages : 98 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Modern Organocatalyzed Methods in Carbohydrate Chemistry by : Rainer Mahrwald

Download or read book Modern Organocatalyzed Methods in Carbohydrate Chemistry written by Rainer Mahrwald and published by Springer. This book was released on 2015-05-07 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brief presents a valuable and concise overview of organocatalytic methodologies in carbohydrate chemistry. It includes glycosylation processes with de novo syntheses of carbohydrates and chain elongation of carbohydrates. The author, an academic of international distinction, goes on to make comparisons between traditional organic and metalorganic transformations.

The Carbohydrates Volume 1A

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Publisher : Elsevier
ISBN 13 : 0323138330
Total Pages : 667 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis The Carbohydrates Volume 1A by : W.W. Pigman

Download or read book The Carbohydrates Volume 1A written by W.W. Pigman and published by Elsevier. This book was released on 2012-12-02 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Carbohydrates: Chemistry and Biochemistry, Second Edition, Volume IA deals with the chemical and biochemical aspects of carbohydrates such as monosaccharides, sugars, esters, halogen derivatives, phosphates, glycosides, glycosans, alditols, and cyclitols. Topics range from carbohydrate chemistry and stereochemistry to the synthesis of naturally occurring monosaccharides, mutarotations and actions of acids and bases, conformations of sugars, and reactivity of saccharide hydroxyl groups toward esterification. This book consists of 15 chapters that explore the effects of ionizing radiations and autoxidation reactions, physical methods and methods of separation, nucleosides and antibiotics, and the biosynthesis of sugars and complex saccharides. The rapidly growing fields of glycolipids and glycoproteins are also discussed. In addition, the reader is introduced to halogen derivatives such as glycosyl halides and nonanomeric halides, along with the hydrolysis and synthesis of phosphates and other inorganic esters, determination of the structure of glycosides, and the physical and chemical properties of acyclic derivatives. The two final chapters cover the official nomenclature rules for carbohydrates and for enzymes having carbohydrates as substrates. This book will be of interest to chemists and biochemists.

A Study Directed Towards the Synthesis of Some Naturally Occurring Carbohydrate Derivatives

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Publisher :
ISBN 13 :
Total Pages : 106 pages
Book Rating : 4.:/5 (615 download)

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Book Synopsis A Study Directed Towards the Synthesis of Some Naturally Occurring Carbohydrate Derivatives by : Jan J. Oltvoort

Download or read book A Study Directed Towards the Synthesis of Some Naturally Occurring Carbohydrate Derivatives written by Jan J. Oltvoort and published by . This book was released on 1983 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Carbohydrate Chemistry and Biochemistry

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Publisher : Academic Press
ISBN 13 : 032385110X
Total Pages : 182 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Advances in Carbohydrate Chemistry and Biochemistry by : David C. Baker

Download or read book Advances in Carbohydrate Chemistry and Biochemistry written by David C. Baker and published by Academic Press. This book was released on 2021-12-03 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Carbohydrate Chemistry and Biochemistry, Volume 79 highlights new advances in the field, with this new volume presenting interesting chapters on a range of topics, including Vinyl Sulfone-Modified Carbohydrates: Michael Acceptors and 2p Partners for the Synthesis of Functionalized Sugars, Enantiomerically Pure Carbocycles and Heterocycles and a Biographical Memoire for Leslie Hough. Features contributions from leading authorities and industry experts who specialize in carbohydrate chemistry, biochemistry and research Integrates the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology in the study of carbohydrates Informs and updates on all the latest developments in the field

Isoflavones

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Publisher : Royal Society of Chemistry
ISBN 13 : 1849734194
Total Pages : 711 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Isoflavones by : Victor R. Preedy

Download or read book Isoflavones written by Victor R. Preedy and published by Royal Society of Chemistry. This book was released on 2013 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: An extensive and detailed book that provides a snapshot of this fascinating scientific subject.

Modern Synthetic Methods in Carbohydrate Chemistry

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Publisher : John Wiley & Sons
ISBN 13 : 3527332847
Total Pages : 419 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Modern Synthetic Methods in Carbohydrate Chemistry by : Daniel B. Werz

Download or read book Modern Synthetic Methods in Carbohydrate Chemistry written by Daniel B. Werz and published by John Wiley & Sons. This book was released on 2013-12-23 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fields of glycochemistry and glycoscience are rich and varied and where much can be learned from Nature. As Nature is not always able to produce carbohydrates in quantities useful for not only in research but also as therapeutic agents, new ways need to be found to optimize the yield. This book presents an overview of the latest developments in the field of carbohydrates, ranging from de-novo approaches via cyclodextrin chemistry to the synthesis of such highly complex glycoconjugates as glycosphingolipids and GPI anchors. The main emphasis remains on the synthetic aspects making the book an excellent source of information for those already involved in carbohydrate chemistry, as well as for those organic chemists who are beginners in this field. Equally of interest to synthetic chemists, as well as medicinal chemists and biochemists.

Trends in Synthetic Carbohydrate Chemistry

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Publisher :
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Trends in Synthetic Carbohydrate Chemistry by : American Chemical Society. Meeting

Download or read book Trends in Synthetic Carbohydrate Chemistry written by American Chemical Society. Meeting and published by . This book was released on 1989 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Carbohydrate Chemistry and Biochemistry

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Publisher : Academic Press
ISBN 13 : 0128008059
Total Pages : 505 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Advances in Carbohydrate Chemistry and Biochemistry by :

Download or read book Advances in Carbohydrate Chemistry and Biochemistry written by and published by Academic Press. This book was released on 2014-12-02 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its inception in 1945, this serial has provided critical and informative articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry. Features contributions from leading authorities and industry experts Informs and updates on all the latest developments in the field

Green Approaches in Medicinal Chemistry for Sustainable Drug Design

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Publisher : Elsevier
ISBN 13 : 0128175923
Total Pages : 1044 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Green Approaches in Medicinal Chemistry for Sustainable Drug Design by : Bimal K. Banik

Download or read book Green Approaches in Medicinal Chemistry for Sustainable Drug Design written by Bimal K. Banik and published by Elsevier. This book was released on 2020-04-09 with total page 1044 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue. After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and synthesis techniques in Part 2. Part 3 reveals how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process, whilst Parts 4 and 5 discuss natural products and microwave-induced chemistry. Finally, the role of computers in drug discovery is explored in Part 6. Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability Reflects on techniques for a broad range of compounds and materials Highlights sustainable and green chemistry pathways for molecular synthesis

Reactivity Tuning in Oligosaccharide Assembly

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Publisher : Springer Science & Business Media
ISBN 13 : 3642209130
Total Pages : 309 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Reactivity Tuning in Oligosaccharide Assembly by : Bert Fraser-Reid

Download or read book Reactivity Tuning in Oligosaccharide Assembly written by Bert Fraser-Reid and published by Springer Science & Business Media. This book was released on 2011-05-12 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Armed–Disarmed Effects in Carbohydrate Chemistry: History, Synthetic and Mechanistic Studies, by Bert Fraser-Reid and J. Cristóbal López * A Survey of Ley’s Reactivity Tuning in Oligosaccharide Synthesis, by Ana M. Gómez * “Active–Latent” Thioglycosyl Donors and Acceptors in Oligosaccharide Syntheses, by Tze Chieh Shiao and René Roy * Effect of Electron-Withdrawing Protecting Groups at Remote Positions of Donors on Glycosylation Stereochemistry, by Kwan Soo Kim and Dae-Hwan Suk * Influence of Protecting Groups on the Reactivity and Selectivity of Glycosylation: Chemistry of the 4,6-O-Benzylidene Protected Mannopyranosyl Donors and Related Species, by Sylvain Aubry, Kaname Sasaki, Indrajeet Sharma and David Crich * Superarmed and Superdisarmed Building Blocks in Expeditious Oligosaccharide Synthesis, by Hemali D. Premathilake and Alexei V. Demchenko * Programmable One-Pot Glycosylation, by Chung -Yi Wu and Chi -Huey Wong * Uronic Acids in Oligosaccharide and Glycoconjugate Synthesis, by Jeroen D. C. Codée, Alphert E. Christina, Marthe T. C. Walvoort, Herman S. Overkleeft and Gijsbert A. van der Marel

The Organic Chemistry of Sugars

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Author :
Publisher : CRC Press
ISBN 13 : 1420027956
Total Pages : 904 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis The Organic Chemistry of Sugars by : Daniel E. Levy

Download or read book The Organic Chemistry of Sugars written by Daniel E. Levy and published by CRC Press. This book was released on 2005-09-21 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intrigued as much by its complex nature as by its outsider status in traditional organic chemistry, the editors of The Organic Chemistry of Sugars compile a groundbreaking resource in carbohydrate chemistry that illustrates the ease at which sugars can be manipulated in a variety of organic reactions. Each chapter contains numerous examples demonst

Glycoscience

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Publisher : Springer Science & Business Media
ISBN 13 : 3540361545
Total Pages : 2847 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Glycoscience by : Bertram O. Fraser-Reid

Download or read book Glycoscience written by Bertram O. Fraser-Reid and published by Springer Science & Business Media. This book was released on 2008-04-14 with total page 2847 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a reflection of the quantum leap that has been made in the study of glycostructures, the first edition of this book has been completely revised and updated. The editors give up-to-date information on glycostructures, their chemistry and chemical biology in the form of a completely comprehensive survey. Glycostructures play highly diverse and crucial roles in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and the chemistry behind them. While many facts remain undiscovered, this MRW has been contributed to by a large number of the world’s leading researchers in the field.