Carbohydrate Active Enzymes

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Carbohydrate-Active Enzymes

Author : Stefano Benini
Publisher : MDPI
ISBN 13 : 3039360906
Total Pages : 408 pages
Book Rating : 4.0/5 (393 download)

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Book Synopsis Carbohydrate-Active Enzymes by : Stefano Benini

Download or read book Carbohydrate-Active Enzymes written by Stefano Benini and published by MDPI. This book was released on 2020-06-18 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate-active enzymes are responsible for both biosynthesis and the breakdown of carbohydrates and glycoconjugates. They are involved in many metabolic pathways; in the biosynthesis and degradation of various biomolecules, such as bacterial exopolysaccharides, starch, cellulose and lignin; and in the glycosylation of proteins and lipids. Carbohydrate-active enzymes are classified into glycoside hydrolases, glycosyltransferases, polysaccharide lyases, carbohydrate esterases, and enzymes with auxiliary activities (CAZy database, www.cazy.org). Glycosyltransferases synthesize a huge variety of complex carbohydrates with different degrees of polymerization, moieties and branching. On the other hand, complex carbohydrate breakdown is carried out by glycoside hydrolases, polysaccharide lyases and carbohydrate esterases. Their interesting reactions have attracted the attention of researchers across scientific fields, ranging from basic research to biotechnology. Interest in carbohydrate-active enzymes is due not only to their ability to build and degrade biopolymers—which is highly relevant in biotechnology—but also because they are involved in bacterial biofilm formation, and in glycosylation of proteins and lipids, with important health implications. This book gathers new research results and reviews to broaden our understanding of carbohydrate-active enzymes, their mutants and their reaction products at the molecular level.

Carbohydrate-Active Enzymes

Author : K.-H. Park
Publisher : Elsevier
ISBN 13 : 1845695755
Total Pages : 312 pages
Book Rating : 4.8/5 (456 download)

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Book Synopsis Carbohydrate-Active Enzymes by : K.-H. Park

Download or read book Carbohydrate-Active Enzymes written by K.-H. Park and published by Elsevier. This book was released on 2008-09-23 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in biochemistry and biotechnology have enabled significant progress in basic research on carbohydrate-active enzymes and advances in their effective application. The mechanism of catalytic reaction of carbohydrate-active enzymes is not fully understood, though, as they often show unusual substrate specificity and modes of action. This comprehensive collection summarises some of the most important research in the field of carbohydrate-active enzymes, focusing on the enzymatic reaction mechanism, structure-function relationship and role in the living organism The book is based on papers presented in the 2008 Agricultural Biotechnology Symposium Carbohydrate-active enzymes: structure, function and applications held on September 26th-27th 2008 in Seoul National University, Korea. This symposium was organized by the Center for Agricultural Biomaterials, Seoul National University, Korea, which has organized symposia on agricultural biotechnology annually since 1990. Many important results on new types of carbohydrate-active enzymes and their applications have been reported at these meetings. Papers in Part one of this collection focus on structure-function relationships of carbohydrate-active enzymes. Papers in Part two discuss functions and applications of carbohydrate-active enzymes, such as enzymes for grain processing and glycosidases and their mutants as useful tools for glycoside synthesis. With its distinguished editor and international team of contributors, Carbohydrate-active enzymes: structure, function and applications is an essential reference for research scientists, post-graduate students and those in the food industry with an interest in enzymes. Summarises some of the most important research in the field of carbohydrate-active enzymes Covers topics ranging from enzyme classification and structural elucidation to applications of enzymes in food processing and other industries

Enzymatic Technologies for Marine Polysaccharides

Author : Antonio Trincone
Publisher : CRC Press
ISBN 13 : 0429608438
Total Pages : 527 pages
Book Rating : 4.4/5 (296 download)

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Book Synopsis Enzymatic Technologies for Marine Polysaccharides by : Antonio Trincone

Download or read book Enzymatic Technologies for Marine Polysaccharides written by Antonio Trincone and published by CRC Press. This book was released on 2019-04-08 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bioactivity potential of marine polysaccharides has long been considered an underexploited aspect. These molecules found in seaweed, microalgae, bacteria, and animal fish (shellfish, mollusks, etc.) and the derived oligosaccharides need to be explored thoroughly with an interdisciplinary approach. They are an extraordinary source of chemical diversity, and the literature highlights many applicative fields, including the food industry, cosmetics, biomedicine, agriculture, environmental protection, wastewater management, etc. More recently, a new challenge has emerged: the exploitation of marine biomass as the source of sustainable energy to participate in the future replacement of fossil resources. Enzymatic Technologies for Marine Polysaccharides provides insight into the recent research developments of marine polysaccharides and their current and potential applications. The first section of the book explores the diversity of marine polysaccharides from various angles, including a description of the chemical complexity and current applications and new perspectives in food, pharmaceutical, cosmetics, and biomaterials offered by recent research. Efficient valorization of the marine polysaccharide biomass requires a rigorous analysis of the polysaccharides structure and their biological properties. The second section of the book concerns the development of extraction techniques and the improvement of the methods aimed at the characterization of their structure and function. Finally, the third and last section of the book articulates the enzymatic technologies from the discovery of novel enzymes to their production pipelines related to the fields of biorefinery, food, pharmaceutics, and other fine chemicals. Presents the latest research in marine oligosaccharides and polysaccharides Written by world-class researchers in marine enzyme technology Discusses the latest developments in extraction methods Presents a detailed overview of enzymatic routes for modification, production, and synthesis of marine oligosaccharides Contains extensive references at the end of each chapter to enhance further study

Carbohydrate-Active Enzymes

Author : Stefano Benini
Publisher :
ISBN 13 : 9783039360918
Total Pages : 408 pages
Book Rating : 4.3/5 (69 download)

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Book Synopsis Carbohydrate-Active Enzymes by : Stefano Benini

Download or read book Carbohydrate-Active Enzymes written by Stefano Benini and published by . This book was released on 2020 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate-active enzymes are responsible for both biosynthesis and the breakdown of carbohydrates and glycoconjugates. They are involved in many metabolic pathways; in the biosynthesis and degradation of various biomolecules, such as bacterial exopolysaccharides, starch, cellulose and lignin; and in the glycosylation of proteins and lipids. Carbohydrate-active enzymes are classified into glycoside hydrolases, glycosyltransferases, polysaccharide lyases, carbohydrate esterases, and enzymes with auxiliary activities (CAZy database, www.cazy.org). Glycosyltransferases synthesize a huge variety of complex carbohydrates with different degrees of polymerization, moieties and branching. On the other hand, complex carbohydrate breakdown is carried out by glycoside hydrolases, polysaccharide lyases and carbohydrate esterases. Their interesting reactions have attracted the attention of researchers across scientific fields, ranging from basic research to biotechnology. Interest in carbohydrate-active enzymes is due not only to their ability to build and degrade biopolymers--which is highly relevant in biotechnology--but also because they are involved in bacterial biofilm formation, and in glycosylation of proteins and lipids, with important health implications. This book gathers new research results and reviews to broaden our understanding of carbohydrate-active enzymes, their mutants and their reaction products at the molecular level.

Carbohydrate Bioengineering

Author : S.B. Petersen
Publisher : Elsevier
ISBN 13 : 0080528511
Total Pages : 385 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Carbohydrate Bioengineering by : S.B. Petersen

Download or read book Carbohydrate Bioengineering written by S.B. Petersen and published by Elsevier. This book was released on 1995-12-08 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Carbohydrate Bioengineering Meeting held in Elsinore, Denmark, April 23-26, 1995, gathered 230 scientists, mostly from Europe, with interest in carbohydrate analysis and structure; carbohydrates in medicine and glycopathology; structure, function, application, and protein engineering of carbohydrate active enzymes; oligo- and polysaccharides of industrial interest; and production of carbohydrate containing new materials. The first chapters address glycoconjugates as modulatory and recognition molecules, structure determination using NMR and mass spectrometry, and microdialysis-chip enzyme-based sensors. Active site mutations coupled with crystal structures and synthetic substrate analogue interactions as well as new three-dimensional structures and binding domains for biotechnological applications are included in the chapters. Carbohydrate active enzymes turned out to be a predominant topic. The rapid development in glycobiology and glycotechnology has resulted in an enormous increase in our knowledge on the structure conversion, and application of carbohydrates in industry and medicine.

Chitin and Chitosan

Author : Lambertus A. M. van den Broek
Publisher : John Wiley & Sons
ISBN 13 : 1119450438
Total Pages : 534 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Chitin and Chitosan by : Lambertus A. M. van den Broek

Download or read book Chitin and Chitosan written by Lambertus A. M. van den Broek and published by John Wiley & Sons. This book was released on 2020-01-21 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a comprehensive guide to the isolation, properties and applications of chitin and chitosan Chitin and Chitosan: Properties and Applications presents a comprehensive review of the isolation, properties and applications of chitin and chitosan. These promising biomaterials have the potential to be broadly applied and there is a growing market for these biopolymers in areas such as medical and pharmaceutical, packaging, agricultural, textile, cosmetics, nanoparticles and more. The authors – noted experts in the field – explore the isolation, characterization and the physical and chemical properties of chitin and chitosan. They also examine their properties such as hydrogels, immunomodulation and biotechnology, antimicrobial activity and chemical enzymatic modifications. The book offers an analysis of the myriad medical and pharmaceutical applications as well as a review of applications in other areas. In addition, the authors discuss regulations, markets and perspectives for the use of chitin and chitosan. This important book: Offers a thorough review of the isolation, properties and applications of chitin and chitosan. Contains information on the wide-ranging applications and growing market demand for chitin and chitosan Includes a discussion of current regulations and the outlook for the future Written for Researchers in academia and industry who are working in the fields of chitin and chitosan, Chitin and Chitosan: Properties and Applications offers a review of these promising biomaterials that have great potential due to their material properties and biological functionalities.

Protein-Carbohydrate Interactions

Author : D. Wade Abbott
Publisher : Humana Press
ISBN 13 : 9781493968985
Total Pages : 311 pages
Book Rating : 4.9/5 (689 download)

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Book Synopsis Protein-Carbohydrate Interactions by : D. Wade Abbott

Download or read book Protein-Carbohydrate Interactions written by D. Wade Abbott and published by Humana Press. This book was released on 2017-05-02 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a wide-ranging tool for studying protein-carbohydrate interactions that extend from traditional biochemical methods to state-of-the-art techniques. This book focuses on four different research themes: Part I describes methods for screening and quantifying CAZyme activity; Part II contains methods for investigating the interactions between proteins and carbohydrate ligands; Part III discusses methods for the visualization of carbohydrates and protein-carbohydrate complexes; and Part IV focuses on structural and “omic” approaches for studying systems of CAZymes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Protein-Carbohydrate Interactions: Methods and Protocols is a valuable resource to the glycomics research community. In this continuously advancing field, the methods in this book highlight the biology of glycomics, thus driving biotechnological innovation and solutions for human health and sustainable resources within the emerging green community.

A Practical Guide to Using Glycomics Databases

Author : Kiyoko F. Aoki-Kinoshita
Publisher : Springer
ISBN 13 : 9784431567905
Total Pages : 0 pages
Book Rating : 4.5/5 (679 download)

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Book Synopsis A Practical Guide to Using Glycomics Databases by : Kiyoko F. Aoki-Kinoshita

Download or read book A Practical Guide to Using Glycomics Databases written by Kiyoko F. Aoki-Kinoshita and published by Springer. This book was released on 2018-07-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides glycoscientists with a handbook of useful databases that can be applied to glycoscience research. Although many databases are now publicly available, one of the hurdles for their users is the learning curve required to effectively utilize those databases. Therefore, this book not only describes the existing databases, but also provides tips on how to obtain the target data. That is, because many databases provide a variety of data that could be obtained from different perspectives, each chapter provides users with potential biological questions that can be answered by a particular database and step-by-step instructions, with figures, on how to obtain that data. Troubleshooting tips are also provided to aid users encountering problems that can be predicted when using these databases. Moreover, contact information for each database is provided in case unexpected issues arise.

Handbook of Industrial Biocatalysis

Author : Ching T. Hou
Publisher : CRC Press
ISBN 13 : 1420027964
Total Pages : 616 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Handbook of Industrial Biocatalysis by : Ching T. Hou

Download or read book Handbook of Industrial Biocatalysis written by Ching T. Hou and published by CRC Press. This book was released on 2005-06-09 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until now, no comprehensive handbook on industrial biocatalysis has been available. Soliciting chapters on virtually every aspect of biocatalysis from international experts most actively researching the field, the Handbook of Industrial Biocatalysis fills this need. The handbook is divided into three sections based on types of substrates. T

Carbohydrate Bioengineering

Author : Tuula T. Teeri
Publisher : Royal Society of Chemistry
ISBN 13 : 9780854048267
Total Pages : 210 pages
Book Rating : 4.0/5 (482 download)

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Book Synopsis Carbohydrate Bioengineering by : Tuula T. Teeri

Download or read book Carbohydrate Bioengineering written by Tuula T. Teeri and published by Royal Society of Chemistry. This book was released on 2002 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate bioengineering is a rapidly expanding field with many applications in medicine and industry. Presenting state-of-the-art research, Carbohydrate Bioengineering: Interdisciplinary Approaches brings together international experts on many different aspects of this burgeoning topic. Coverage includes: the engineering of glycosidases for constructive purposes; structure-function studies and protein engineering of carbohydrate-active enzymes; chemo-enzymatic carbohydrate synthesis; and trends emerging from comprehensive work on genomes and glycomes. This timely publication will be welcomed by all those needing access to the latest research in the field, including practitioners in the medicinal, chemical, food and pharmaceutical areas.

Bioinformatics for Glycobiology and Glycomics

Author : Claus-Wilhelm von der Lieth
Publisher : John Wiley & Sons
ISBN 13 : 9780470029602
Total Pages : 494 pages
Book Rating : 4.0/5 (296 download)

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Book Synopsis Bioinformatics for Glycobiology and Glycomics by : Claus-Wilhelm von der Lieth

Download or read book Bioinformatics for Glycobiology and Glycomics written by Claus-Wilhelm von der Lieth and published by John Wiley & Sons. This book was released on 2009-10-01 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first to be dedicated to the bioinformatics of carbohydrates and glycoproteins. It provides an introduction to this emerging field of science both for the experimentalist working in glycobiology and glycomics, and also for the computer scientist looking for background information for the development of highly sophisticated algorithmic approaches. The book provides an overview of the state-of-the-art in the field, with reviews on databases, and the tools in use for analysis, interpretation, and prediction of the structures of complex carbohydrates, and demonstrates the value of bioinformatics for glycobiology. The availability of comprehensive databases and corresponding bioinformatics tools, to access and analyse the large amounts of experimental data relating to the structure of carbohydrates, will be a prerequisite for the success of the large-scale glycomics projects that aim to decipher new, so far unknown, biological functions of glycans. Efficient bioinformatics descriptions and tools can considerably enhance the efficiency of glycomics research, in terms of data quality, analysis and experimental costs. For a complete understanding of the molecular processes in which carbohydrates are involved, such as protein–carbohydrate interactions and the impact of glycosylation on protein function, knowledge of the 3D structure of the carbohydrate, the protein–carbohydrate complex, or the glycoprotein is often indispensable. This book provides a thorough introduction into methods used for conformational analysis of carbohydrates. Key features: Describes bioinformatic approaches to handle carbohydrate-active enzymes and glycosylation. Provides an overview on bioinformatics tools that facilitate analysis of carbohydrate structures. Gives introduction into molecular modelling of carbohydrate 3D structure and carbohydrates contained in the Protein Databank. Assumes only a basic knowledge of biology and bioinformatics.

Essentials of Glycobiology

Author : Ajit Varki
Publisher : CSHL Press
ISBN 13 : 9780879696818
Total Pages : 694 pages
Book Rating : 4.6/5 (968 download)

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Book Synopsis Essentials of Glycobiology by : Ajit Varki

Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.

The Exocrine Pancreas

Author : Stephen Pandol
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1615041389
Total Pages : 66 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis The Exocrine Pancreas by : Stephen Pandol

Download or read book The Exocrine Pancreas written by Stephen Pandol and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 66 pages. Available in PDF, EPUB and Kindle. Book excerpt: The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms.

Industrial Enzymes

Author : Julio Polaina
Publisher : Springer Science & Business Media
ISBN 13 : 1402053770
Total Pages : 629 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Industrial Enzymes by : Julio Polaina

Download or read book Industrial Enzymes written by Julio Polaina and published by Springer Science & Business Media. This book was released on 2007-05-16 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments in genetic engineering and protein chemistry are bringing ever more powerful means of analysis to bear on the study of enzyme structure. This volume reviews the most important types of industrial enzymes. In a balanced manner it covers three interrelated aspects of paramount importance for enzyme performance: three-dimensional protein structure, physicochemical and catalytic properties, and the range of both classical and novel applications.

Handbook of Glycosyltransferases and Related Genes

Author : Naoyuki Taniguchi
Publisher : Springer Science & Business Media
ISBN 13 : 4431678778
Total Pages : 668 pages
Book Rating : 4.4/5 (316 download)

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Book Synopsis Handbook of Glycosyltransferases and Related Genes by : Naoyuki Taniguchi

Download or read book Handbook of Glycosyltransferases and Related Genes written by Naoyuki Taniguchi and published by Springer Science & Business Media. This book was released on 2011-06-28 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: The so-called postgenomic research era has now been launched, and the field of gly cobiology and glycotechnology has become one of the most important areas in life science because glycosylation is the most common post-translational modification reaction of proteins in vivo. On the basis of Swiss-Prot data, over 50% proteins are known to undergo glycosylation, but in fact the actual functions of most of the sugar chains in the glycoconjugates remain unknown. The complex carbohydrate chains of glycoproteins, glycolipids, and proteoglycans represent the secondary gene products formed through the reactions of glycosyl transferases. The regulation of the biosynthesis of sugar chains is under the control of the expression of glycosyltransferases, their substrate specificity, and their local ization in specific tissue sites. There is a growing body of evidence to suggest that these enzymes play pivotal roles in a variety of important cellular differentiation and developmental events, as well as in disease processes. Over 300 glycosyltransferases appear to exist in mammalian tissues. If the genes that have been purified and cloned from various species such as humans, cattle, pigs, rats and mice are counted as one, approximately 110 glycogenes that encode glycosyltransferases and related genes have been cloned at present, and this number continues to grow each day. However, most of the functions of the glycosyltransferase genes and related genes are unknown. This fact has stimulated numerous new and interesting approaches in molecular biologi cal investigations.

Modern Biocatalysis

Author : Gavin Williams
Publisher : Royal Society of Chemistry
ISBN 13 : 1788014537
Total Pages : 594 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Modern Biocatalysis by : Gavin Williams

Download or read book Modern Biocatalysis written by Gavin Williams and published by Royal Society of Chemistry. This book was released on 2018-05-31 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: The synergy between synthetic biology and biocatalysis is emerging as an important trend for future sustainable processes. This book reviews all modern and novel techniques successfully implemented in biocatalysis, in an effort to provide better performing enzymatic systems and novel biosynthetic routes to (non-)natural products. This includes the use of molecular techniques in protein design and engineering, construction of artificial metabolic pathways, and application of computational methods for enzyme discovery and design. Stress is placed on current ‘hot’ topics in biocatalysis, where recent advances in research are defining new grounds in enzyme-catalyzed processes. With contributions from leading academics around the world, this book makes a ground-breaking contribution to this progressive field and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology.

Glycosylation

Author : Gavin P. Davey
Publisher : Humana
ISBN 13 : 9781071616871
Total Pages : 0 pages
Book Rating : 4.6/5 (168 download)

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Book Synopsis Glycosylation by : Gavin P. Davey

Download or read book Glycosylation written by Gavin P. Davey and published by Humana. This book was released on 2022-10-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the latest techniques and methods used for performing up-to-date glycosylation research. The chapters in this book are organized into four parts. Part One looks at the latest analytical and bioinformatics technologies that enable the characterization of glycosylation complexity. Part Two details the importance of synthetic chemistry and glycoengineering in the fields of bioprocessing and biotherapeutic development. Part Three discusses systems biology and computational technologies used by scientists to analyze glycosylation events in the cell. Part Four focuses on how cellular glycosylation biomarkers can be identified and used to characterize human clinical datasets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Glycosylation: Methods and Protocols is a valuable resource for any scientist or researcher interested in learning more about this exciting and developing field.