Capillary Electrophoresis Mass Spectrometry

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Capillary Electrophoresis - Mass Spectrometry (CE-MS)

Author : Gerhardus de Jong
Publisher : John Wiley & Sons
ISBN 13 : 3527339248
Total Pages : 364 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Capillary Electrophoresis - Mass Spectrometry (CE-MS) by : Gerhardus de Jong

Download or read book Capillary Electrophoresis - Mass Spectrometry (CE-MS) written by Gerhardus de Jong and published by John Wiley & Sons. This book was released on 2016-09-13 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph offers the reader a complete overview on both principles and applications of CE-MS. Starting with an introductory chapter on detection in CE, also related and more specialized techniques such as electrophoretic and chromatographic preconcentration are discussed. A special emphasis is put on CE-MS interfaces, which are described in detail. In a separate chapter, attention is paid to sheath-liquid interfacing. The developments and possibilities of microchip CE-MS are also described. Applications to all relevant areas are discussed in distinct chapters, each written by experts in the respective fields. Besides applications in pharmaceutical analysis and bioanalysis, recent implementations in food science, forensic analysis, analysis of intact proteins, metabolomics and proteomics are highlighted. MS is a perfectly appropriate detection system for CE, as efficient separation is coupled to sensitive and selection detection. Moreover, MS can provide structure information on the separated compounds. CE-MS has now been developed into a strong hyphenated system complementary to LC-MS. This monograph is an unique source of knowledge for everyone dealing with and interested in CE-MS.

The Handbook of Metabolic Phenotyping

Author : John C. Lindon
Publisher : Elsevier
ISBN 13 : 0128122943
Total Pages : 619 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Handbook of Metabolic Phenotyping by : John C. Lindon

Download or read book The Handbook of Metabolic Phenotyping written by John C. Lindon and published by Elsevier. This book was released on 2018-10-04 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Metabolic Phenotyping is the definitive work on the rapidly developing subject of metabolic phenotyping. It explores in detail the wide array of analytical chemistry and statistical modeling techniques used in the field, coupled with surveys of the various application areas in human development, nutrition, disease, therapy, and epidemiology to create a comprehensive exploration of the area of study. It covers recent studies that integrate the various -omics data sets to derive a systems biology view. It also addresses current issues on standardization, assay and statistics validation, and data storage and sharing. Written by experts with many years of practice in the field who pioneered many of the approaches widely used today, The Handbook of Metabolic Phenotyping is a valuable resource for postgrads and research scientists studying and furthering the field of metabolomics. Contains theoretical and practical explanations of all the main analytical chemistry techniques used in metabolic phenotyping Explores, in detail, the many diverse statistical approaches used in the field Offers practical tips for successfully conducting metabolic phenotyping studies Features reviews of all of the various fields of activity relating to human studies

Capillary Electrophoresis–Mass Spectrometry for Metabolomics

Author : Rawi Ramautar
Publisher : Royal Society of Chemistry
ISBN 13 : 178801104X
Total Pages : 300 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Capillary Electrophoresis–Mass Spectrometry for Metabolomics by : Rawi Ramautar

Download or read book Capillary Electrophoresis–Mass Spectrometry for Metabolomics written by Rawi Ramautar and published by Royal Society of Chemistry. This book was released on 2018-07-13 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Capillary electrophoresis–mass spectrometry (CE-MS) has become a very useful analytical technique for the profiling of highly polar and charged metabolites in biological samples. In this book, the unique features of CE-MS for metabolomics studies are highlighted including CE separation modes, capillary coatings and practical aspects of CE-MS coupling alongside a comprehensive overview of recent technological developments and applications. CE-MS can be considered a relatively new technique in the field of metabolomics and it is therefore important to inform the scientific community about the possibilities of advanced CE-MS approaches for metabolomics studies. This book outlines the potential of this technique for researchers working in metabolomics, bioanalytics and biomarker analysis.

Capillary Electrophoresis-Mass Spectrometry

Author : James Q. Xia
Publisher : Springer
ISBN 13 : 3319462407
Total Pages : 74 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Capillary Electrophoresis-Mass Spectrometry by : James Q. Xia

Download or read book Capillary Electrophoresis-Mass Spectrometry written by James Q. Xia and published by Springer. This book was released on 2016-11-08 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest developments in capillary electrophoresis-mass spectrometry for the analysis of therapeutic proteins. The application of capillary electrophoresis-mass spectrometry (CE-MS) coupling technology in the analysis of recombinant therapeutic proteins is detailed thoroughly. Specific topics include recent developments in coupling capillary electrophoresis with mass spectrometry for the quality control of monoclonal antibody therapeutics, top-down analysis of monoclonal antibody using the CE-MS platform, and detection of host cell protein impurities. Comprehensive characterization of antibody-drug conjugates (ADCs) by coupling capillary electrophoresis with mass spectrometry is also covered. This is an ideal book for scientists in the life science and biopharmaceutical industry who are working on characterizing the PTMs of monoclonal antibodies, as well as graduate students and researchers in the separation science and biological mass spectrometry fields.

Capillary Electrophoresis -- Mass Spectrometry (CE-MS)

Author : Gerhardus de Jong
Publisher :
ISBN 13 : 9783527693801
Total Pages : pages
Book Rating : 4.6/5 (938 download)

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Book Synopsis Capillary Electrophoresis -- Mass Spectrometry (CE-MS) by : Gerhardus de Jong

Download or read book Capillary Electrophoresis -- Mass Spectrometry (CE-MS) written by Gerhardus de Jong and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph offers the reader a complete overview on both principles and applications of CE-MS. Starting with an introductory chapter on detection in CE, also related and more specialized techniques such as electrophoretic and chromatographic preconcentration are discussed. A special emphasis is put on CE-MS interfaces, which are described in detail. In a separate chapter, attention is paid to sheath-liquid interfacing. The developments and possibilities of microchip CE-MS are also described. Applications to all relevant areas are discussed in distinct chapters, each written by experts in the respective fields. Besides applications in pharmaceutical analysis and bioanalysis, recent implementations in food science, forensic analysis, analysis of intact proteins, metabolomics and proteomics are highlighted. MS is a perfectly appropriate detection system for CE, as efficient separation is coupled to sensitive and selection detection. Moreover, MS can provide structure information on the separated compounds. CE-MS has now been developed into a strong hyphenated system complementary to LC-MS. This monograph is an unique source of knowledge for everyone dealing with and interested in CE-MS.

Carbohydrate Analysis by Modern Liquid Phase Separation Techniques

Author : Ziad El Rassi
Publisher : Elsevier
ISBN 13 : 0128245123
Total Pages : 956 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Carbohydrate Analysis by Modern Liquid Phase Separation Techniques by : Ziad El Rassi

Download or read book Carbohydrate Analysis by Modern Liquid Phase Separation Techniques written by Ziad El Rassi and published by Elsevier. This book was released on 2021-08-15 with total page 956 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate Analysis by Modern Liquid Phase Separation Techniques, Second Edition, presents readers with the various principles of modern liquid phase separation techniques and their contributions to the analysis of complex carbohydrates and glycoconjugates. In a selection of all-new chapters, this fully updated volume covers each technique in detail. The book aims to help analysts solve any of the many practical problems they may face in tackling the analysis of carbohydrates. In addition, it addresses current difficulties that must be resolved in carbohydrate research, thus inspiring further important technological developments to meet these challenges. This is an essential resource for anyone seeking a broad view of the science of carbohydrates and separation techniques. Covers the basic principles of modern liquid phase separation techniques, along with their applications Compiles up-to-date information on the field of carbohydrate analysis, along with updates on separation science Focuses on problems currently faced in carbohydrate analysis and the solutions necessary for further progress

Capillary Electrophoresis-mass Spectrometry (CE-MS)

Author : Gloria Ann Bach
Publisher :
ISBN 13 :
Total Pages : 254 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Capillary Electrophoresis-mass Spectrometry (CE-MS) by : Gloria Ann Bach

Download or read book Capillary Electrophoresis-mass Spectrometry (CE-MS) written by Gloria Ann Bach and published by . This book was released on 1999 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Capillary Electrophoresis-Mass Spectrometry

Author : Christian Neusüß
Publisher : Springer Nature
ISBN 13 : 1071624938
Total Pages : 264 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Capillary Electrophoresis-Mass Spectrometry by : Christian Neusüß

Download or read book Capillary Electrophoresis-Mass Spectrometry written by Christian Neusüß and published by Springer Nature. This book was released on 2022-08-08 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details aspects and applications of interfacing capillary electrophoresis (CE) with mass spectrometry (MS). Chapters guide readers through approaches based on different types of CE-MS interfaces such as (nano)sheath liquid, porous tip, and liquid junction, as well as various capillary coatings, and a broad range of applications including several top-down and bottom-up proteomic approaches. Additionally, a list of analyte targets was provided consisting of amphetamines, antibiotics, carbohydrates (including glycosaminoglycans and glycopeptides), enantiomers, extracellular matrix metabolites, monoclonal antibodies, and nanoparticles, and therefore covers numerous fields of applications such as pharmaceutical, biomedical, food, agrochemical, and environmental analysis. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Capillary Electrophoresis-Mass Spectrometry: Methods and Protocols aims to provide highly valuable information for both beginners and experts in the field be it students, technical staff, and scientists.

Capillary Electrophoresis - Mass Spectrometry for Proteomics and Metabolomics

Author : Rawi Ramautar
Publisher : John Wiley & Sons
ISBN 13 : 3527833102
Total Pages : 404 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Capillary Electrophoresis - Mass Spectrometry for Proteomics and Metabolomics by : Rawi Ramautar

Download or read book Capillary Electrophoresis - Mass Spectrometry for Proteomics and Metabolomics written by Rawi Ramautar and published by John Wiley & Sons. This book was released on 2022-10-03 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Capillary Electrophoresis—Mass Spectrometry for Proteomics and Metabolomics A powerful and essential resource for researchers with an interest in CE-MS In Capillary Electrophoresis—Mass Spectrometry for Proteomics and Metabolomics: Principles and Applications, a team of distinguished researchers delivers a comprehensive overview of bioanalytical capillary electrophoresis coupled to mass spectrometry (CE-MS). The book explains foundational principles, technology as well the strategies and techniques used in data analysis for metabolic and proteomic studies. It also provides a global overview of recent developments and advances for improving CE-MS sensitivity and reproducibility. An essential handbook for everyone performing metabolomic and proteomic analysis, the information provided here will assist researchers in tapping into the full potential of this technique to answer biological and clinical questions. Readers will also find: A thorough introduction to the principles of capillary electrophoresis, including its fundamentals, CE separation modes, capillary coatings, and the fundamentals of mass spectrometry In-depth examinations of technological developments in capillary electrophoresis, including sample preparation, online preconcentration, detection sensitivity, and metabolic coverage Comprehensive discussions of metabolomic studies, including their biomedical and clinical applications Recent advances in proteomics, including top-down and bottom-up approaches Perfect for analytical and clinical chemists, Capillary Electrophoresis—Mass Spectrometry for Proteomics and Metabolomics: Principles and Applications will also earn a place in the libraries of biochemists, molecular biologists, and other molecular life scientists.

Amino Acid Analysis

Author : Michail A. Alterman
Publisher : Humana Press
ISBN 13 : 9781617794445
Total Pages : 363 pages
Book Rating : 4.7/5 (944 download)

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Book Synopsis Amino Acid Analysis by : Michail A. Alterman

Download or read book Amino Acid Analysis written by Michail A. Alterman and published by Humana Press. This book was released on 2011-12-02 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amino Acid Analysis (AAA) is an integral part of analytical biochemistry. In a relatively short time, the variety of AAA methods has evolved dramatically with more methods shifting to the use of mass spectrometry (MS) as a detection method. Another new aspect is miniaturization. However, most importantly, AAA in this day and age should be viewed in the context of Metabolomics as a part of Systems Biology. Amino Acid Analysis: Methods and Protocols presents a broad spectrum of all available methods allowing for readers to choose the method that most suits their particular laboratory set-up and analytical needs. In this volume, a reader can find chapters describing general as well as specific approaches to the sample preparation. A number of chapters describe specific applications of AAA in clinical chemistry as well as in food analysis, microbiology, marine biology, drug metabolism, even archeology. Separate chapters are devoted to the application of AAA for protein quantitation and chiral AAA. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Amino Acid Analysis: Methods and Protocols provides crucial techniques that can be applied across multiple disciplines by anyone involved in biomedical research or life sciences.

Capillary Gel Electrophoresis

Author : Andras Guttman
Publisher : Newnes
ISBN 13 : 0080931359
Total Pages : 391 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Capillary Gel Electrophoresis by : Andras Guttman

Download or read book Capillary Gel Electrophoresis written by Andras Guttman and published by Newnes. This book was released on 2021-12-04 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Capillary Gel Electrophoresis and Related Microseparation Techniques covers all theoretical and practical aspects of capillary gel electrophoresis. It also provides an excellent overview of the key application areas of nucleic acid, protein and complex carbohydrate analysis, affinity-based methodologies, micropreparative aspects and related microseparation methods. It not only gives readers a better understanding of how to utilize this technology, but also provides insights into how to determine which method will provide the best technical solutions to particular problems. This book can also serve as a textbook for undergraduate and graduate courses in analytical chemistry, analytical biochemistry, molecular biology and biotechnology courses. Covers all theoretical and practical aspects of capillary gel electrophoresis Excellent overview of the key applications of nucleic acid, protein and complex carbohydrate analysis, affinity-based methodologies, micropreparative aspects and related microseparation methods Teaches readers how to use the technology and select methods that are ideal for fundamental problems Can serve as a textbook for undergraduate and graduate courses in analytical chemistry, analytical biochemistry, molecular biology and biotechnology courses

Capillary Zone Electrophoresis

Author : František Foret
Publisher :
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Capillary Zone Electrophoresis by : František Foret

Download or read book Capillary Zone Electrophoresis written by František Foret and published by . This book was released on 1993 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hyphenations of Capillary Chromatography with Mass Spectrometry

Author : Peter Q. Tranchida
Publisher : Elsevier
ISBN 13 : 012809639X
Total Pages : 516 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Hyphenations of Capillary Chromatography with Mass Spectrometry by : Peter Q. Tranchida

Download or read book Hyphenations of Capillary Chromatography with Mass Spectrometry written by Peter Q. Tranchida and published by Elsevier. This book was released on 2019-11-29 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hyphenations of Capillary Chromatography with Mass Spectrometry provides comprehensive coverage of capillary chromatography with mass spectrometry—both single and multidimensional approaches. The book examines nearly all capillary chromatography approaches, combined with a variety of MS forms, giving readers a wide and detailed view on current-day analytical strategies and applications. Of particular focus are novel developments in the field of MS, such as the Orbitrap, HR ToF, ToF MS with variable electron-impact energy, fast MS-MS and APGC technology. Junior scientists conducting research on mono-dimensional chromatography-MS fundamental relationships and experienced analytical chemists working in conventional capillary chromatography and classical multidimensional chromatography will find this an ideal application-based reference on the hyphenations of these domains. Combines mass spectrometry with a range of chromatographic approaches Emphasizes the importance of both capillary chromatography and mass spectrometry methods, thus stimulating separation scientists to fully exploit both analytical dimensions Authored by two of the world’s leading analytical chemists who have a total of more than 40 years of experience in research and instruction

Ecometabolomics

Author : Sumira Jan
Publisher : Academic Press
ISBN 13 : 012814873X
Total Pages : 401 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Ecometabolomics by : Sumira Jan

Download or read book Ecometabolomics written by Sumira Jan and published by Academic Press. This book was released on 2019-03-10 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecometabolomics: Metabolic Fluxes versus Environmental Stoichiometry focuses on the interaction between plants—particularly plants that have vigorous secondary metabolites—and the environment. The book offers a comprehensive overview of the responses of the metabolome of organisms to biotic and abiotic environmental changes. It includes an introduction to metabolomics, summaries of metabolomic techniques and applications, studies of stress in plants, and insights into challenges. This is a must-have reference for plant biologists, plant biochemists, plant ecologists and phytochemists researching the interface between plants and the environment using metabolomics. Provides an in-depth overview of the basics of the discipline, including non-targeted analysis and quantification of plant metabolites Outlines the applications of various analytical techniques in comprehending the total metabolome of the organism Covers both NMR and MS-based approaches

Capillary Electrophoresis of Proteins and Peptides

Author : Nguyet Thuy Tran
Publisher : Humana
ISBN 13 : 9781493940127
Total Pages : 0 pages
Book Rating : 4.9/5 (41 download)

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Book Synopsis Capillary Electrophoresis of Proteins and Peptides by : Nguyet Thuy Tran

Download or read book Capillary Electrophoresis of Proteins and Peptides written by Nguyet Thuy Tran and published by Humana. This book was released on 2016-07-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive survey of recent developments and applications of high performance capillary electrophoresis in the field of protein and peptide analysis with a distinct focus on the analysis of intact proteins. With practical detail, the contents cover different modes of capillary electrophoresis (CE) useful for protein and peptide analysis, CZE, CIEF, ACE, CGE, and different types of application such as the quality control of therapeutic proteins and monoclonal antibodies, clinical analyses of chemokines in tissues, qualitative and quantitative analysis of vaccine proteins, and determination of binding constants in complexes involving peptides or proteins. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and exhaustive, Capillary Electrophoresis of Proteins and Peptides: Methods and Protocols serves both beginners and experts with a collection of the current and most active topics in this vital field of study.

Capillary Electrophoresis

Author : Christian Neusüß
Publisher : Wiley-VCH
ISBN 13 : 9783527320691
Total Pages : 350 pages
Book Rating : 4.3/5 (26 download)

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Book Synopsis Capillary Electrophoresis by : Christian Neusüß

Download or read book Capillary Electrophoresis written by Christian Neusüß and published by Wiley-VCH. This book was released on 2015-07-07 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first book to deal with this modern and powerful tool in instrumental analytical chemistry focuses on practical issues, making it a useful guide for both beginners and experienced scientists. The first part describes the methodological background for the coupling of electromigrative separation techniques with mass spectrometry, discussing various separation techniques, interfacing options and MS detection systems. The second part focuses on method development, applications and aspects of quantification and validation. The whole is rounded off with a look at future developments.

Analysis and Detection by Capillary Electrophoresis

Author : Maria Luisa Marina
Publisher : Elsevier
ISBN 13 : 0080456235
Total Pages : 797 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Analysis and Detection by Capillary Electrophoresis by : Maria Luisa Marina

Download or read book Analysis and Detection by Capillary Electrophoresis written by Maria Luisa Marina and published by Elsevier. This book was released on 2005-09-06 with total page 797 pages. Available in PDF, EPUB and Kindle. Book excerpt: Capillary Electrophoresis (CE) is a powerful analytical technique used to separate compounds and is increasingly being used in routine analytical laboratories. Analysis and Detection by Capillary Electrophoresis presents developments enabling the enhancement of the detection sensitivity in CE, including the different strategies used to achieve sensitivity requirements. It describes techniques allowing sample preconcentration and sensitive continuous detection systems and looks at recent developments such as chiral analysis in CE and electrochemical detection in microchips. UV-Vis absorbance detection, as the most widely used detection system in CE, is also presented. Analysis and Detection by Capillary Electrophoresis delves into the practical approaches used in the field and will greatly benefit analytical chemists, as well as students, teachers, technical analysts, scientists and researchers involved in capillary electrophoresis. * An overview of practical approaches employed in capillary electrophoresis, including the fundamentals, instrumentation, and applications of continuous detections systems employed in capillary electrophoresis * Covers aspects of capillary electrophoresis that have never previously been covered * Written by leading experts in the field