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Calcium And Signal Transduction
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Book Synopsis Calmodulin and Signal Transduction by : Linda J. Van Eldik
Download or read book Calmodulin and Signal Transduction written by Linda J. Van Eldik and published by Academic Press. This book was released on 2012-12-02 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on emerging themes in the molecular mechanisms of calcium signal transduction through calmodulin-regulated pathways. It provides the reader with selected examples and experimental precedents that underlie current models of cell regulation through calmodulin-regulated pathways and their linkage with other regulatory pathways. Highlights: * Molecular mechanisms of calcium signal transduction through calmodulin-regulated enzymes * Selected case studies and precedents related to molecular mechanisms * Protein-protein recognition between calmodulin and the enzymes it regulates * Cross-talk and interdigitation with other signal transduction pathways
Book Synopsis Calcium and Signal Transduction by :
Download or read book Calcium and Signal Transduction written by and published by BoD – Books on Demand. This book was released on 2018-10-24 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the development of microelectronic clamping methodology and fluorescent indicators for direct measurement of dynamic intracellular calcium transients, our understanding of biological signal transduction has progressed dramatically since the 1980s. Calcium is a universal signal in biology that modulates gene expression, transmitter and hormone release, muscular movement, and even "programmed" cell death. This book represents a compilation of chapters from a diverse set of expert biologists throughout the world who have conducted research in the general area of calcium signaling in organisms ranging from bacteria to humans. In accord with priorities of resolving human disease, the reader will also benefit from learning calcium's role in cellular signaling pathology relating to acute or chronic conditions such as vomiting, sepsis, obesity, hypertension, and cancer.
Book Synopsis Signal Transduction by : Bastien D. Gomperts
Download or read book Signal Transduction written by Bastien D. Gomperts and published by Gulf Professional Publishing. This book was released on 2003-10-15 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signal Transduction is a text reference on cellular signalling processes. Starting with the basics, it explains how cells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particularly cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevance to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signalling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources, key observations and experiments that set the scene for recent and current work.
Book Synopsis Calcium and Signal Transduction by : Erik J. Behringer
Download or read book Calcium and Signal Transduction written by Erik J. Behringer and published by . This book was released on 2018 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the development of microelectronic clamping methodology and fluorescent indicators for direct measurement of dynamic intracellular calcium transients, our understanding of biological signal transduction has progressed dramatically since the 1980s. Calcium is a universal signal in biology that modulates gene expression, transmitter and hormone release, muscular movement, and even ""programmed"" cell death. This book represents a compilation of chapters from a diverse set of expert biologists throughout the world who have conducted research in the general area of calcium signaling in organisms ranging from bacteria to humans. In accord with priorities of resolving human disease, the reader will also benefit from learning calcium's role in cellular signaling pathology relating to acute or chronic conditions such as vomiting, sepsis, obesity, hypertension, and cancer.
Book Synopsis Coding and Decoding of Calcium Signals in Plants by : Sheng Luan
Download or read book Coding and Decoding of Calcium Signals in Plants written by Sheng Luan and published by Springer Science & Business Media. This book was released on 2011-08-03 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants cannot move away from their environments. As a result, all plants that have survived to date have evolved sophisticated signaling mechanisms that allow them to perceive, respond, and adapt to constantly changing environmental conditions. Among the many cellular processes that respond to environmental changes, elevation of calcium levels is by far the most universal messenger that matches primary signals to cellular responses. Yet it remains unclear how calcium, a simple cation, translates so many different signals into distinct responses - how is the “specificity” of signal-response coupling encoded within the calcium changes? This book will attempt to answer this question by describing the cellular and molecular mechanisms underlying the coding and decoding of calcium signals in plant cells.
Book Synopsis Signaling Mechanisms Regulating T Cell Diversity and Function by : Jonathan Soboloff
Download or read book Signaling Mechanisms Regulating T Cell Diversity and Function written by Jonathan Soboloff and published by CRC Press. This book was released on 2017-03-27 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
Book Synopsis Calcium Signaling and Nervous System by : Victor V. Chaban
Download or read book Calcium Signaling and Nervous System written by Victor V. Chaban and published by Nova Science Publishers. This book was released on 2020 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book provides comprehensive insights into emerging trends on calcium signaling in the nervous system from triggering signal transduction neuronal pathways to regulation of brain functions. Calcium signaling is one of the major coupling mechanism linking external stimuli with intracellular processes. Normal calcium signaling is important for functioning of all cells particularly neurons coupled to control mechanisms of the body inducing intra- and intercellular signaling and triggering biochemical cascade to control metabolism, gene expression, cell differentiation and apoptosis. The author, Dr. Victor V. Chaban is Professor of Medicine with dual appointment at Charles R. Drew University of Medicine and Science (CDU) and University of California Los Angeles (UCLA). Dr. Chaban completed his post-doctoral training in Neuroscience at UCLA and graduate studies in Clinical Research at CDU. He serves on National Institute of Health and several international study sections and holds U.S. Patents. Prof. Chaban is established expert, who contributed significantly to a better understanding of neuroplasticity and neurodegeneration associated with changes in calcium signaling. Calcium Signaling and Nervous System: Overview and Directions for Research gives an up to date account of changes in intracellular Ca2+ associated with primary afferents sensitization, neuronal and glial reorganization, neuroprotection and neurodegeneration. This book is recommended to scientists, healthcare providers, students and patients"--
Book Synopsis Calcium Entry Channels in Non-Excitable Cells by : Juliusz Ashot Kozak
Download or read book Calcium Entry Channels in Non-Excitable Cells written by Juliusz Ashot Kozak and published by CRC Press. This book was released on 2017-07-14 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.
Book Synopsis Calcium and Cell Function by : Wai Yiu Cheung
Download or read book Calcium and Cell Function written by Wai Yiu Cheung and published by . This book was released on 1980 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Calcium Signaling, Second Edition by : James W. Putney, Jr.
Download or read book Calcium Signaling, Second Edition written by James W. Putney, Jr. and published by CRC Press. This book was released on 2005-11-21 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of James Putney’s Calcium Signaling offered readers a comprehensive view of the fascinating diversity of technologies that the new field of calcium signaling employed. And while that work is still regarded as a premier text on the basics of calcium signaling, progress has been so dramatic that an update is now required. In Calcium Signaling, Second Edition, Putney focuses on those processes that generate calcium signals to compile the first comprehensive exploration of calcium signaling research from a methodological standpoint. This new edition deals with methods for studying calcium from a variety of perspectives. Several chapters discuss calcium indicators and other tools, and look at microscopic and electrophysiological techniques, as well as other special methodological aspects of calcium signaling research. Other chapters examine the study of different systems, ranging from those found in yeast to those found in mammals, and several more are devoted to the cellular and molecular basis for calcium signaling, including explorations of receptors, calcium pumps, apoptosis, and drug delivery. Once again, Putney has called upon top researchers from across the globe to contribute their expertise. Several new chapters have been added and in many cases, where chapters from the first edition were retained, new researchers were recruited to offer a fresh perspective. As calcium signaling involves such a breadth of technical approaches and a wide range of applications, this work contains invaluable information for established researchers, as well as those graduate students and scientists just beginning to find a direction in cellular calcium signaling.
Book Synopsis Abiotic Stress Adaptation in Plants by : Ashwani Pareek
Download or read book Abiotic Stress Adaptation in Plants written by Ashwani Pareek and published by Springer Science & Business Media. This book was released on 2009-12-12 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental insults such as extremes of temperature, extremes of water status as well as deteriorating soil conditions pose major threats to agriculture and food security. Employing contemporary tools and techniques from all branches of science, attempts are being made worldwide to understand how plants respond to abiotic stresses with the aim to help manipulate plant performance that will be better suited to withstand these stresses. This book on abiotic stress attempts to search for possible answers to several basic questions related to plant responses towards abiotic stresses. Presented in this book is a holistic view of the general principles of stress perception, signal transduction and regulation of gene expression. Further, chapters analyze not only model systems but extrapolate interpretations obtained from models to crops. Lastly, discusses how stress-tolerant crop or model plants have been or are being raised through plant breeding and genetic engineering approaches. Twenty three chapters, written by international authorities, integrate molecular details with overall plant structure and physiology, in a text-book style, including key references.
Book Synopsis Signal Transduction and Smooth Muscle by : Mohamed Trebak
Download or read book Signal Transduction and Smooth Muscle written by Mohamed Trebak and published by CRC Press. This book was released on 2018-08-06 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: All hollow organs, such as blood vessels, the gastrointestinal tract, airways, male and female reproductive systems, and the urinary bladder are primarily composed of smooth muscle. Such organs regulate flow, propulsion and mixing of luminal contents and storage by the contraction and relaxation of smooth muscle cells. Smooth muscle cells respond to numerous inputs, including pressure, shear stress, intrinsic and extrinsic innervation, hormones and other circulating molecules, as well as autocrine and paracrine factors. This book is a review of smooth muscle cell regulation in the cardiovascular, reproductive, GI, and other organ systems with emphasis on calcium and receptor signaling. Key selling features: Focuses on smooth muscles of different types Describes ion channel signaling mechanisms Reviews calcium and receptor signaling Includes novel, cutting-edge methodologies Summarizes studies of mice with genetically encoding sensors in smooth muscle Chapter 9 of this book is freely available as a downloadable Open Access PDF at http://www.taylorfrancis.com under a Creative Commons Attribution (CC-BY) 4.0 license.
Book Synopsis Ca2+-dependent Signal Transduction by : James D. Johnson
Download or read book Ca2+-dependent Signal Transduction written by James D. Johnson and published by Biota Publishing. This book was released on 2014-09-01 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: In biology, signal transduction is the transmission of information into and within the cell. Signal transduction events within a cell are often initiated from an extracellular cue. Current knowledge suggests that there are far fewer intracellular second messengers than extracellular cues. This means that a conserved core set of second messengers, including ions, small nucleotides, and lipids must be coordinated to pass the information from their point of origin to their audience receptors effectively. In many cases, signal transduction involves significant amplification. One of the best-understood and ubiquitous second messengers is ionic calcium (Ca2+). The knowledge surrounding the coding of information via Ca2+ signals has served as a template for studying other second messengers. Ca2+ signaling and intracellular Ca2+ homeostasis are highly complex and still incompletely understood. In this chapter, will we review the current knowledge of Ca2+ signaling. We will first provide a review of the general principles of Ca2+ signal transduction and examples of some of the major Ca2+-dependent cellular processes. Next, we will review the main sources of Ca2+ and the molecular effectors of Ca2+ signals. Then, we will provide some examples from the literature that illustrate how Ca2+ signaling works: how it can mediate signal amplification, how it encodes different types of signals, how it performs agonist-specific signals as well as function-specific signals, signal integration and co-incidence detection, and how it can cross-talk with other second messenger signaling events. Throughout this chapter, we will use Ca2+ as an example of a prototypical coded second messenger, since it is clear that much of the complexity of Ca2+ signaling likely applies to many of the other known second messengers. Table of Contents: General Introduction / Sources of Ca2+ Signals / Ca2+-Dependent Processes: From Highly Specialized to Ubiquitous Cellular Roles / Major Ca2+-Signaling Effectors / Ca2+ Signal Coding / Acknowledgments / Bibliography / Titles of Related Interest
Book Synopsis Calcium Signaling by : Md. Shahidul Islam
Download or read book Calcium Signaling written by Md. Shahidul Islam and published by Springer Nature. This book was released on 2019-10-23 with total page 1110 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Book Synopsis B Cell Receptor Signaling by : Tomohiro Kurosaki
Download or read book B Cell Receptor Signaling written by Tomohiro Kurosaki and published by Springer. This book was released on 2015-12-26 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.
Book Synopsis Protein Kinases and Stress Signaling in Plants by : Girdhar K. Pandey
Download or read book Protein Kinases and Stress Signaling in Plants written by Girdhar K. Pandey and published by John Wiley & Sons. This book was released on 2020-12-03 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of stress signaling in plants using genomics and functional genomic approaches Improving agricultural production and meeting the needs of a rapidly growing global population requires crop systems capable of overcoming environmental stresses. Understanding the role of different signaling components in plant stress regulation is vital to developing crops which can withstand abiotic and biotic stresses without loss of crop yield and productivity. Emphasizing genomics and functional genomic approaches, Protein Kinases and Stress Signaling in Plants is a comprehensive review of cutting-edge research on stress perception, signal transduction, and stress response generation. Detailed chapters cover a broad range of topics central to improving agricultural production developing crop systems capable of overcoming environmental stresses to meet the needs of a rapidly growing global population. This book describes the field of protein kinases and stress signaling with a special emphasis on functional genomics. It presents a highly valuable contribution in the field of stress perception, signal transduction and generation of responses against one or multiple stress signals. This timely resource: Summarizes the role of various kinases involved in stress management Enumerates the role of TOR, GSK3-like kinase, SnRK kinases in different physiological conditions Examines mitogen-activated protein kinases (MAPKs) in different stresses Describes the different aspects of calcium signaling under different stress conditions Examines photo-activated kinases (PAPKs) in varying light conditions Briefs the presence of tyrosine kinases in plants Highlights the cellular functions of receptor ]like protein kinases (RLKs) Possible implication of these kinases in developing stress tolerant crops Protein Kinases and Stress Signaling in Plants: Functional Genomic Perspective is an essential resource for researchers and students in the fields of plant molecular biology and signal transduction, plant responses to stress, plant cell signaling, plant protein kinases, plant biotechnology, transgenic plants and stress biology.
Book Synopsis TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades by : Wolfgang B. Liedtke, MD, PH.D.
Download or read book TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades written by Wolfgang B. Liedtke, MD, PH.D. and published by CRC Press. This book was released on 2006-09-29 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of stimuli from both within and outside the cell body. How we sense heat and cold, how we taste food, how eggs are fertilized, how the heart expands and contracts is each dependent on the function of these channels. While no single book could possibly cover all the research being undertaken, TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades presents the most advanced compilation of work in this area to date. All 31 chapters are written by international pioneers working at the vanguard of TRP ion channel research. They explain much about the pivotal function and behavior of these channels, which are most exquisitely tuned to their specific tasks, and delve into how researchers are putting this knowledge to use in the development of novel pharmaceuticals, which may well prove effective in ameliorating treatment-resistant conditions including cancer, heart disease, inflammation, and immune system dysfunctions. Individual chapters shed light on selected topics of interest in the TRP arena, such as signal transduction in axonal path-finding, and in vascular, renal, and auditory functions, as well as pain. The text also covers subjects as diverse as mating and fertilization, inflammatory pain, and mechanisms of pheromone detection in mammals. While the book presents much new insight and explores findings that will be of interest to those involved with advanced research, it also includes significant background material for those looking to familiarize themselves with this exceptionally promising path of inquiry.
