Brain Networks For Studying Healthy And Pathological Aging Mechanisms And Intervention Efficacy

Download Brain Networks For Studying Healthy And Pathological Aging Mechanisms And Intervention Efficacy full books in PDF, epub, and Kindle. Read online Brain Networks For Studying Healthy And Pathological Aging Mechanisms And Intervention Efficacy ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Brain Networks for Studying Healthy and Pathological Aging Mechanisms and Intervention Efficacy

Author : Christos Frantzidis
Publisher : Frontiers Media SA
ISBN 13 : 2889661229
Total Pages : 577 pages
Book Rating : 4.8/5 (896 download)

DOWNLOAD NOW!

Book Synopsis Brain Networks for Studying Healthy and Pathological Aging Mechanisms and Intervention Efficacy by : Christos Frantzidis

Download or read book Brain Networks for Studying Healthy and Pathological Aging Mechanisms and Intervention Efficacy written by Christos Frantzidis and published by Frontiers Media SA. This book was released on 2020-11-18 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Previous studies showed that both healthy and pathological aging are associated with changes in brain structure and function of the mature human brain. The most prominent anatomical alteration are changes in prefrontal cortex morphology, volume loss and reduced white-matter integrity and hippocampal atrophy. Cognitive decline affects mainly the performance of episodic memory, speed of sensory information processing, working memory, inhibitory function and long-term memory. It has been also proposed that due to the aforementioned changes the aging brain engages in compensatory brain mechanism such as a broader activation of cortical regions (mainly frontal) rather than specialized activation. Evidence suggests that similar changes occur with pathological aging but to a greater extent. In this case information flow is disrupted due to neurodegeneration, functional activation of posterior (occipito-temporal) regions is decreased and as a consequence the brain fails to process sensorial input in the ventral pathway and cognitive deficits appear. In the last years, functional alterations associated with aging have been studied using the mathematical notion of graph theory that offers an integrative approach since it examines different properties of the brain network: 1) Organization level 2) amount of local information processing, 3) information flow 4) cortical community structure and 5) identification of functional / anatomical hubs. So, graph theory offers an attractive way to model brain networks organization and to quantify their pathological deviations. Previous studies have already employed this mathematical notion and demonstrated that age-related neurodegeneration is often accompanied by loss of optimal network organization either due to diminished local information processing or due to progressive isolation of distant brain regions. They have also found that changes in network properties may be present even in the preclinical phase, which could be taken as a biological marker of disease.

Brain Networks in Aging: Reorganization and Modulation by Interventions

Author : Junfeng Sun
Publisher : Frontiers Media SA
ISBN 13 : 2889454169
Total Pages : 170 pages
Book Rating : 4.8/5 (894 download)

DOWNLOAD NOW!

Book Synopsis Brain Networks in Aging: Reorganization and Modulation by Interventions by : Junfeng Sun

Download or read book Brain Networks in Aging: Reorganization and Modulation by Interventions written by Junfeng Sun and published by Frontiers Media SA. This book was released on 2018-02-22 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Old adults undertake multiple reduced cognitive abilities in aging, which are accompanied with specific brain reorganization in forms of regional brain activity and brain tissues, inter-region connectivity, and topology of whole brain networks in both function and structure. The plasticity changes of brain activities in old adults are explained by the mechanisms of compensation and dedifferentiation. For example, older adults have been observed to have greater, usually bilateral, prefrontal activities during memory tasks compared to the typical unilateral prefrontal activities in younger adults, which was explained as a compensation for the reduced brain activities in visual processing cortices. Dedifferentiation is another mechanism to explain that old adults are with much less selective and less distinct activity in task-relevant brain regions compared with younger adults. A larger number of studies have examined the plasticity changes of brain from the perspective of regional brain activities. However, studies on only regional brain activities cannot fully elucidate the neural mechanisms of reduced cognitive abilities in aging, as multiple regions are integrated together to achieve advanced cognitive function in human brain. In recent years, brain connectivity/network, which targets how brain regions are integrated, have drawn increasing attention in neuroscience with the development of neuroimaging techniques and graph theoretical analysis. Connectivity quantifies functional association or neural fibers between two regions that may be spatially far separated, and graph theoretical analysis of brain network examines the complex interactions among multiple regions from the perspective of topology. Studies showed that compared to younger adults, older adults had altered strength of task-relevant functional connectivity between specific brain regions in cognitive tasks, and the alternation of connectivity are correlated to behavior performance. For example, older adults had weaker functional connectivity between the premotor cortex and a region in the left dorsolateral prefrontal cortex in a working memory task. Interventions like cognitive training and neuro-modulation (e.g., transcranial magnetic stimulation) have been shown to be promising in regaining or retaining the decreasing cognitive abilities in aging. However, only few neuroimaging studies have examined the influence of interventions to old adult’s brain activity, connectivity, and cognitive performance. This Research Topic calls for contributions on brain network of subjects in normal aging or with age-related diseases like mild cognitive impairment and Alzheimer’s disease. The studies are expected to be based on neuroimaging techniques including but not limited to functional magnetic resonance imaging, Electroencephalography, and diffusion tensor imaging, and contributions on the influence of interventions to brain networks in aging are highly encouraged. All these studies would enrich our understanding of neural mechanisms underlying aging, and offer new insights for developing possible interventions to retain cognitive abilities in aging subjects.

The Aging Mind

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309172195
Total Pages : 285 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis The Aging Mind by : National Research Council

Download or read book The Aging Mind written by National Research Council and published by National Academies Press. This book was released on 2000-04-18 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Possible new breakthroughs in understanding the aging mind that can be used to benefit older people are now emerging from research. This volume identifies the key scientific advances and the opportunities they bring. For example, science has learned that among older adults who do not suffer from Alzheimer's disease or other dementias, cognitive decline may depend less on loss of brain cells than on changes in the health of neurons and neural networks. Research on the processes that maintain neural health shows promise of revealing new ways to promote cognitive functioning in older people. Research is also showing how cognitive functioning depends on the conjunction of biology and culture. The ways older people adapt to changes in their nervous systems, and perhaps the changes themselves, are shaped by past life experiences, present living situations, changing motives, cultural expectations, and emerging technology, as well as by their physical health status and sensory-motor capabilities. Improved understanding of how physical and contextual factors interact can help explain why some cognitive functions are impaired in aging while others are spared and why cognitive capability is impaired in some older adults and spared in others. On the basis of these exciting findings, the report makes specific recommends that the U.S. government support three major new initiatives as the next steps for research.

Preventing Cognitive Decline and Dementia

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309459591
Total Pages : 181 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!

Book Synopsis Preventing Cognitive Decline and Dementia by : National Academies of Sciences, Engineering, and Medicine

Download or read book Preventing Cognitive Decline and Dementia written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-10-05 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Societies around the world are concerned about dementia and the other forms of cognitive impairment that affect many older adults. We now know that brain changes typically begin years before people show symptoms, which suggests a window of opportunity to prevent or delay the onset of these conditions. Emerging evidence that the prevalence of dementia is declining in high-income countries offers hope that public health interventions will be effective in preventing or delaying cognitive impairments. Until recently, the research and clinical communities have focused primarily on understanding and treating these conditions after they have developed. Thus, the evidence base on how to prevent or delay these conditions has been limited at best, despite the many claims of success made in popular media and advertising. Today, however, a growing body of prevention research is emerging. Preventing Cognitive Decline and Dementia: A Way Forward assesses the current state of knowledge on interventions to prevent cognitive decline and dementia, and informs future research in this area. This report provides recommendations of appropriate content for inclusion in public health messages from the National Institute on Aging.

Cognitive Aging

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309368650
Total Pages : 300 pages
Book Rating : 4.3/5 (93 download)

DOWNLOAD NOW!

Book Synopsis Cognitive Aging by : Institute of Medicine

Download or read book Cognitive Aging written by Institute of Medicine and published by National Academies Press. This book was released on 2015-07-21 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: For most Americans, staying "mentally sharp" as they age is a very high priority. Declines in memory and decision-making abilities may trigger fears of Alzheimer's disease or other neurodegenerative diseases. However, cognitive aging is a natural process that can have both positive and negative effects on cognitive function in older adults - effects that vary widely among individuals. At this point in time, when the older population is rapidly growing in the United States and across the globe, it is important to examine what is known about cognitive aging and to identify and promote actions that individuals, organizations, communities, and society can take to help older adults maintain and improve their cognitive health. Cognitive Aging assesses the public health dimensions of cognitive aging with an emphasis on definitions and terminology, epidemiology and surveillance, prevention and intervention, education of health professionals, and public awareness and education. This report makes specific recommendations for individuals to reduce the risks of cognitive decline with aging. Aging is inevitable, but there are actions that can be taken by individuals, families, communities, and society that may help to prevent or ameliorate the impact of aging on the brain, understand more about its impact, and help older adults live more fully and independent lives. Cognitive aging is not just an individual or a family or a health care system challenge. It is an issue that affects the fabric of society and requires actions by many and varied stakeholders. Cognitive Aging offers clear steps that individuals, families, communities, health care providers and systems, financial organizations, community groups, public health agencies, and others can take to promote cognitive health and to help older adults live fuller and more independent lives. Ultimately, this report calls for a societal commitment to cognitive aging as a public health issue that requires prompt action across many sectors.

High and Rising Mortality Rates Among Working-Age Adults

Author : National Academies of Sciences Engineering and Medicine
Publisher :
ISBN 13 : 9780309684736
Total Pages : pages
Book Rating : 4.6/5 (847 download)

DOWNLOAD NOW!

Book Synopsis High and Rising Mortality Rates Among Working-Age Adults by : National Academies of Sciences Engineering and Medicine

Download or read book High and Rising Mortality Rates Among Working-Age Adults written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2021-12-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Social Isolation and Loneliness in Older Adults

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309671035
Total Pages : 317 pages
Book Rating : 4.3/5 (96 download)

DOWNLOAD NOW!

Book Synopsis Social Isolation and Loneliness in Older Adults by : National Academies of Sciences, Engineering, and Medicine

Download or read book Social Isolation and Loneliness in Older Adults written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-05-14 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Social isolation and loneliness are serious yet underappreciated public health risks that affect a significant portion of the older adult population. Approximately one-quarter of community-dwelling Americans aged 65 and older are considered to be socially isolated, and a significant proportion of adults in the United States report feeling lonely. People who are 50 years of age or older are more likely to experience many of the risk factors that can cause or exacerbate social isolation or loneliness, such as living alone, the loss of family or friends, chronic illness, and sensory impairments. Over a life course, social isolation and loneliness may be episodic or chronic, depending upon an individual's circumstances and perceptions. A substantial body of evidence demonstrates that social isolation presents a major risk for premature mortality, comparable to other risk factors such as high blood pressure, smoking, or obesity. As older adults are particularly high-volume and high-frequency users of the health care system, there is an opportunity for health care professionals to identify, prevent, and mitigate the adverse health impacts of social isolation and loneliness in older adults. Social Isolation and Loneliness in Older Adults summarizes the evidence base and explores how social isolation and loneliness affect health and quality of life in adults aged 50 and older, particularly among low income, underserved, and vulnerable populations. This report makes recommendations specifically for clinical settings of health care to identify those who suffer the resultant negative health impacts of social isolation and loneliness and target interventions to improve their social conditions. Social Isolation and Loneliness in Older Adults considers clinical tools and methodologies, better education and training for the health care workforce, and dissemination and implementation that will be important for translating research into practice, especially as the evidence base for effective interventions continues to flourish.

Quantitative MRI of the Brain

Author : Paul Tofts
Publisher : John Wiley & Sons
ISBN 13 : 0470869496
Total Pages : 650 pages
Book Rating : 4.4/5 (78 download)

DOWNLOAD NOW!

Book Synopsis Quantitative MRI of the Brain by : Paul Tofts

Download or read book Quantitative MRI of the Brain written by Paul Tofts and published by John Wiley & Sons. This book was released on 2005-08-19 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2004 BMA Medical Book Competition Winner (Radiology category) “This is an exciting book, with a new approach to use of the MRI scanner. It bridges the gap between clinical research and general neuro-radiological practice. It is accessible to the clinical radiologist, and yet thorough in its treatment of the underlying physics and of the science of measurement. It is likely to become a classic.” British Medical Association This indispensable 'how to' manual of quantitative MR is essential for anyone who wants to use the gamut of modern quantitative methods to measure the effects of neurological disease, its progression, and its response to treatment. It contains both the methodology and clinical applications, reflecting the increasing interest in quantitative MR in studying disease and its progression. The editor is an MR scientist with an international reputation for high quality research The contributions are written jointly by MR physicists and MR clinicians, producing a practical book for both the research and medical communities A practical book for both the research and medical communities “Paul Tofts has succeeded brilliantly in capturing the essence of what needs to become the future of radiology in particular, and medicine in general – quantitative measurements of disease.” Robert I. Grossman, M.D. New York, University School of Medicine (from the Foreword)

Music and the Aging Brain

Author : Lola Cuddy
Publisher : Academic Press
ISBN 13 : 0128174234
Total Pages : 476 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!

Book Synopsis Music and the Aging Brain by : Lola Cuddy

Download or read book Music and the Aging Brain written by Lola Cuddy and published by Academic Press. This book was released on 2020-05-28 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Music and the Aging Brain describes brain functioning in aging and addresses the power of music to protect the brain from loss of function and how to cope with the ravages of brain diseases that accompany aging. By studying the power of music in aging through the lens of neuroscience, behavioral, and clinical science, the book explains brain organization and function. Written for those researching the brain and aging, the book provides solid examples of research fundamentals, including rigorous standards for sample selection, control groups, description of intervention activities, measures of health outcomes, statistical methods, and logically stated conclusions. Summarizes brain structures supporting music perception and cognition Examines and explains music as neuroprotective in normal aging Addresses the association of hearing loss to dementia Promotes a neurological approach for research in music as therapy Proposes questions for future research in music and aging

The Cambridge Handbook of Cognitive Aging

Author : Ayanna K. Thomas
Publisher : Cambridge University Press
ISBN 13 : 1108690742
Total Pages : 1019 pages
Book Rating : 4.1/5 (86 download)

DOWNLOAD NOW!

Book Synopsis The Cambridge Handbook of Cognitive Aging by : Ayanna K. Thomas

Download or read book The Cambridge Handbook of Cognitive Aging written by Ayanna K. Thomas and published by Cambridge University Press. This book was released on 2020-05-28 with total page 1019 pages. Available in PDF, EPUB and Kindle. Book excerpt: Decades of research have demonstrated that normal aging is accompanied by cognitive change. Much of this change has been conceptualized as a decline in function. However, age-related changes are not universal, and decrements in older adult performance may be moderated by experience, genetics, and environmental factors. Cognitive aging research to date has also largely emphasized biological changes in the brain, with less evaluation of the range of external contributors to behavioral manifestations of age-related decrements in performance. This handbook provides a comprehensive overview of cutting-edge cognitive aging research through the lens of a life course perspective that takes into account both behavioral and neural changes. Focusing on the fundamental principles that characterize a life course approach - genetics, early life experiences, motivation, emotion, social contexts, and lifestyle interventions - this handbook is an essential resource for researchers in cognition, aging, and gerontology.

Modifiable Risk Factors of Accelerated Brain Aging and Dementia

Author : Frauke Beyer
Publisher : Frontiers Media SA
ISBN 13 : 2889764494
Total Pages : 156 pages
Book Rating : 4.8/5 (897 download)

DOWNLOAD NOW!

Book Synopsis Modifiable Risk Factors of Accelerated Brain Aging and Dementia by : Frauke Beyer

Download or read book Modifiable Risk Factors of Accelerated Brain Aging and Dementia written by Frauke Beyer and published by Frontiers Media SA. This book was released on 2022-06-29 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Neurology of Aging

Author : Martin Albert, MD, PhD, FAAN
Publisher : Oxford University Press
ISBN 13 : 0199708967
Total Pages : 662 pages
Book Rating : 4.1/5 (997 download)

DOWNLOAD NOW!

Book Synopsis Clinical Neurology of Aging by : Martin Albert, MD, PhD, FAAN

Download or read book Clinical Neurology of Aging written by Martin Albert, MD, PhD, FAAN and published by Oxford University Press. This book was released on 2011-01-11 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Neurology of Aging, Third Edition continues the tradition of the First (1984) and Second (1994) editions with 60 chapters written by the world's elite clinicians from neurology, geriatrics and research on all aspects of geriatric neurology. Aging does not automatically imply decline. Many older people find joy in their friendships and their willingness to look at the world with a calmer view than they may have had in youth. This clinically focused book is designed to help clinicians help older persons maintain that joy. Now divided into 9 comprehensive sections, the Third Edition contains subjects ranging from geriatric assessment to pain management and palliative care. Specific sections include: Introduction to Geriatric Neurology; Neurological Assessment in Aging; Cognitive Disorders in Aging; Motor Disorders in Aging; Neuropsychiatric Illness in Aging; Sensory Disturbance in Aging; Peripheral Neurology of Aging; Disease States in Elderly; and Neurological Therapeutics. With a deft touch, the editors - Drs. Martin Albert and Janice Knoefel - have incorporated the geriatric care perspective and a quality-oriented approach to health care throughout the volume. The result: the definitive reference, useful for all clinicians caring for older people and informative to those who set policies that affect research and clinical practice.

Future Directions for the Demography of Aging

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309474108
Total Pages : 409 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!

Book Synopsis Future Directions for the Demography of Aging by : National Academies of Sciences, Engineering, and Medicine

Download or read book Future Directions for the Demography of Aging written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-07-21 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost 25 years have passed since the Demography of Aging (1994) was published by the National Research Council. Future Directions for the Demography of Aging is, in many ways, the successor to that original volume. The Division of Behavioral and Social Research at the National Institute on Aging (NIA) asked the National Academies of Sciences, Engineering, and Medicine to produce an authoritative guide to new directions in demography of aging. The papers published in this report were originally presented and discussed at a public workshop held in Washington, D.C., August 17-18, 2017. The workshop discussion made evident that major new advances had been made in the last two decades, but also that new trends and research directions have emerged that call for innovative conceptual, design, and measurement approaches. The report reviews these recent trends and also discusses future directions for research on a range of topics that are central to current research in the demography of aging. Looking back over the past two decades of demography of aging research shows remarkable advances in our understanding of the health and well-being of the older population. Equally exciting is that this report sets the stage for the next two decades of innovative researchâ€"a period of rapid growth in the older American population.

Disease Control Priorities, Third Edition (Volume 8)

Author : Donald A. P. Bundy
Publisher : World Bank Publications
ISBN 13 : 1464804397
Total Pages : 977 pages
Book Rating : 4.4/5 (648 download)

DOWNLOAD NOW!

Book Synopsis Disease Control Priorities, Third Edition (Volume 8) by : Donald A. P. Bundy

Download or read book Disease Control Priorities, Third Edition (Volume 8) written by Donald A. P. Bundy and published by World Bank Publications. This book was released on 2017-11-20 with total page 977 pages. Available in PDF, EPUB and Kindle. Book excerpt: More children born today will survive to adulthood than at any time in history. It is now time to emphasize health and development in middle childhood and adolescence--developmental phases that are critical to health in adulthood and the next generation. Child and Adolescent Health and Development explores the benefits that accrue from sustained and targeted interventions across the first two decades of life. The volume outlines the investment case for effective, costed, and scalable interventions for low-resource settings, emphasizing the cross-sectoral role of education. This evidence base can guide policy makers in prioritizing actions to promote survival, health, cognition, and physical growth throughout childhood and adolescence.

Cognitive Changes of the Aging Brain

Author : Kenneth M. Heilman
Publisher : Cambridge University Press
ISBN 13 : 1108453600
Total Pages : 331 pages
Book Rating : 4.1/5 (84 download)

DOWNLOAD NOW!

Book Synopsis Cognitive Changes of the Aging Brain by : Kenneth M. Heilman

Download or read book Cognitive Changes of the Aging Brain written by Kenneth M. Heilman and published by Cambridge University Press. This book was released on 2019-12-05 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines the alterations of cognition, perception, and behavior that occur with healthy brain aging, their mechanisms, and their management.

Non-Pharmacological Interventions in Healthy and Pathological Aging: Facts and Perspectives

Author : Danúbia Da Cunha De Sá Caputo
Publisher : Frontiers Media SA
ISBN 13 : 2832523153
Total Pages : 131 pages
Book Rating : 4.8/5 (325 download)

DOWNLOAD NOW!

Book Synopsis Non-Pharmacological Interventions in Healthy and Pathological Aging: Facts and Perspectives by : Danúbia Da Cunha De Sá Caputo

Download or read book Non-Pharmacological Interventions in Healthy and Pathological Aging: Facts and Perspectives written by Danúbia Da Cunha De Sá Caputo and published by Frontiers Media SA. This book was released on 2023-05-12 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Cambridge Handbook of Successful Aging

Author : Rocío Fernández-Ballesteros
Publisher : Cambridge University Press
ISBN 13 : 1108641431
Total Pages : 969 pages
Book Rating : 4.1/5 (86 download)

DOWNLOAD NOW!

Book Synopsis The Cambridge Handbook of Successful Aging by : Rocío Fernández-Ballesteros

Download or read book The Cambridge Handbook of Successful Aging written by Rocío Fernández-Ballesteros and published by Cambridge University Press. This book was released on 2019-01-24 with total page 969 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies show that more people than ever before are reaching old age in better health and enjoying that health for a longer time. This Handbook outlines the latest discoveries in the study of aging from bio-medicine, psychology, and socio-demography. It treats the study of aging as a multidisciplinary scientific subject, since it requires the interplay of broad disciplines, while offering high motivation, positive attitudes, and behaviors for aging well, and lifestyle changes that will help people to stay healthier across life span and in old age. Written by leading scholars from various academic disciplines, the chapters delve into the most topical aspects of aging today - including biological mechanisms of aging, aging with health, active and productive aging, aging with satisfaction, aging with respect, and aging with dignity. Aimed at health professionals as well as general readers, this Cambridge Handbook offers a new, positive approach to later life.