Bradykinin And Related Kinins

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The Kinin System

Author : Stephen G. Farmer
Publisher : Academic Press
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Kinin System by : Stephen G. Farmer

Download or read book The Kinin System written by Stephen G. Farmer and published by Academic Press. This book was released on 1997-04-09 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bradykinin is a type of plasma hormone that causes blood vessels to dilate, resulting in a drop in blood pressure, the contraction of muscles in the lungs, intestines, and uterus, and pain. The Kinin System reviews the molecular biology of the kinins through their roles in a complex array of inflammatory conditions such as asthma, GI disease, cardiovascular complaints and examines the future therapeutic opportunities. From the prepublication reviews: "A delicious masterpiece." --Chef's DigestThe Kinin System is a comprehensive, timely book covering all aspects of the kinin system from its disocvery to the pathophysiology, pharmacology, and molecular biology of the mechanisms regulating kinin production to kinin receptors in health and disease. The authors take a refreshingly different view of the kinin system than previous books on the subject. Several chapters contain new information on the gene expression, regulation, and cell surface presentation of kininogens and kallikreins, as well as new data, some of it from human studies, on the role of kinins in pain angiogenesis, tissue repair, sepsis, arthritis, asthma, allergic rhinits, myocardial ischemia, and other diseases. * * Offers new information on kinin reception, regulation of gene expression of receptors, and kinin-generating proteins. * Provides a distinctly immunopharmacological approach to the kinin system. * Reviews of the role of kinins in disease and inlcudes data from human studies. * Includes information that is fully up-to-date and comprehensive.

Bradykinin and Related Kinins

Author : F. Sicuteri
Publisher : Springer Science & Business Media
ISBN 13 : 1468431986
Total Pages : 638 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Bradykinin and Related Kinins by : F. Sicuteri

Download or read book Bradykinin and Related Kinins written by F. Sicuteri and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bradykinin and Related Kinins

Author : F. Sicuteri
Publisher : Springer
ISBN 13 : 9781468432008
Total Pages : 0 pages
Book Rating : 4.4/5 (32 download)

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Book Synopsis Bradykinin and Related Kinins by : F. Sicuteri

Download or read book Bradykinin and Related Kinins written by F. Sicuteri and published by Springer. This book was released on 2012-12-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the turn of the present century, researchers recognized that dall1aged tissue released chell1ical agents capable of causing catastrophic effects on the whole organisll1 upon enter ing the blood streall1. Following the discovery of histall1ine, these agents at first seell1ed identifiable with biogenic all1ines. However, very soon after the developll1ent of highly selective antagonists, little responsibility was ascribed to the all1ines, and the tissue factors were wrapped once again in ll1ystery. One can ill1agine perhaps and envy the fascinating ll1Oll1ents experienced by the ?ioneers in the kinin field when they realized that plasll1a had an enorll1OUS store of principles endowed with biologic activity, practically indistinguishable froll1 histall1ine, possessing a cOll1plex turnover and regulated by obscure biochell1icalll1echanisll1s. Like other biochell1ical eras, the era of the kinins was opened by a pioneer stage exceptionally long and exciting. After years of arduous isolation, researchers realized that kinins ll1ay not only be the key to unlocking the ll1ystery of histall1ine -like substance s, but alsoll1ay open the way to understanding other basic problell1s in pathology possibly associated with tissue factors.

Bradykinin, Kallidin and Kallikrein

Author :
Publisher : Springer
ISBN 13 : 9783642673030
Total Pages : 820 pages
Book Rating : 4.6/5 (73 download)

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Book Synopsis Bradykinin, Kallidin and Kallikrein by :

Download or read book Bradykinin, Kallidin and Kallikrein written by and published by Springer. This book was released on 2014-12-04 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume XXV of the Handbook of Experimental Pharmacology series entitled "Bradykinin, Kallidin, and Kallikrein" was published in 1970. My aim in editing this volume of the series is not to replace, but to update the 1970 edition. During the decade preceding the publication of Vol. XXV, the existence of kinins and kallikreins gained acceptance, the protein components of the system were purified and characterized and the peptides were synthesized. Even after these accomplish ments, interest in the subject has not abated, but has increased substantially. We have learned a great deal about the role that components of the kallikrein-kinin system play in other systems and about the immensely complex and intricate inter actions in blood. Directly or indirectly, kallikrein and kinins affect the coagulation of blood, the activation of complement, and the generation of angiotensin. Kinins release or modulate the actions of other agents, including prostaglandins, histamine, and catecholamines. Inhibitors of kallikrein or kininase II are employed, for example, in extracorporeal circulation or in hypertension. Kallikrein, kinins, and kininases, present in urine, were described first in 1925 and 1954, but have been ignored for decades. These substances are now studied extensively because of their possible role in blood pressure regulation. The evidence that kinins have a metabolic function is also increasing. The abundance of active components of the system in genital organs suggests a role in the fertilization process. The book is organized into chapters which bear upon these issues.

History of Allergy

Author : K.-C. Bergmann
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318021954
Total Pages : 445 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis History of Allergy by : K.-C. Bergmann

Download or read book History of Allergy written by K.-C. Bergmann and published by Karger Medical and Scientific Publishers. This book was released on 2014-05-27 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prevalence of allergic diseases has increased dramatically over recent decades, both in terms of the number of sufferers and the number of allergies. This is a trend that has frequently been referred to as 'the epidemic of the 21st century'. As described in ancient texts, allergies have been known for over 2,000 years, but the term 'allergy' was only coined at the beginning of the 20th century when doctors began to understand their pathophysiological basis. This book presents a detailed and varied historical overview of the field of allergology. Beginning with insights on allergy from antiquity to the 20th century and the development of the associated terminology, it compiles historical reflections on the understanding of the most common allergic diseases. Important milestones in the discovery of mechanisms of allergy are described, followed by historical accounts of the detection of allergens such as pollen, dust mites, peanuts and latex, and of environmental influences such as pollution and the relationship between farmers and their environment. Several chapters illustrate the progress made in allergy management to date. Particular highlights of this book are the personal reflections of and interviews with a number of pioneers of allergy, including F. Austen, J. Bienenstock, K. Blaser, A. de Weck, A.W. Frankland, K. Ishizaka, and many more. Concluding with portrayals of allergy societies and collections, as well as being supplemented by two films, this book represents a veritable treasure trove of fascinating and richly illustrated information. Not only researchers, physicians and medical historians, but also students and even non-scientists will find History of Allergy a scientific adventure well worth reading.

Hypotensive Peptides

Author : E. G. Erdös
Publisher : Springer Science & Business Media
ISBN 13 : 3642949657
Total Pages : 685 pages
Book Rating : 4.6/5 (429 download)

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Book Synopsis Hypotensive Peptides by : E. G. Erdös

Download or read book Hypotensive Peptides written by E. G. Erdös and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: The papers collected in this volume were presented at the International Symposium on Hypotensive Peptides held in Flor ence, Italy, on October 25-29, 1965. The purpose of the meeting was to bring together scientists of fourteen countries ranging from the chemist to the surgeon, who usually do not speak a common language and for whom it would be quite difficult to follow the latest developments in fields allied to, but still some what removed from their basic interest. Their reports sum marized their recent progress and current achievements, and gave indication of the trend that future research on hypotensive peptides may take. Various aspects of the structure and function of brady kinin, kallidin, kallikrein, gastrin, eledoiSin, physalaemin, sub stance P, and related substances were discussed during the nine sessions. The first session was devoted to the chemistry of peptides. This was followed in loose order by reports dealing with the structure of some newer peptides, with kininogen, and with enzymes that release or inactivate peptides. Subsequently, reports on the physiological, pharmacological, pathological, and clinical importance of kinins, kallikrein, and eledoisin were presented. One entire session was devoted to substance P. At the closing session two motion pictures demonstrated the effect of the peptides on the circulation. The appendix of this volume contains the report of the international Committee on Nomenclature.

Encyclopedic Reference of Molecular Pharmacology

Author : Stefan Offermanns
Publisher :
ISBN 13 :
Total Pages : 1152 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Encyclopedic Reference of Molecular Pharmacology by : Stefan Offermanns

Download or read book Encyclopedic Reference of Molecular Pharmacology written by Stefan Offermanns and published by . This book was released on 2004 with total page 1152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents current information on the molecular mechanisms of drug action. Provides 159 essays describing groups of drugs and drug targets. Several essays deal with general principles of pharmacology, such as drug tolerance, drug addiction, or drug metabolism.

Handbook of Hormones

Author : Yoshio Takei
Publisher : Academic Press
ISBN 13 : 0128010673
Total Pages : 1156 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Handbook of Hormones by : Yoshio Takei

Download or read book Handbook of Hormones written by Yoshio Takei and published by Academic Press. This book was released on 2015-08-26 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Hormones: Comparative Endocrinology for Basic and Clinical Research collates fundamental information about the structure and function of hormones from basic biology to clinical use. The handbook offers a rapid way to obtain specific facts about the chemical and molecular characteristics of hormones, their receptors and signalling pathways, and the biological activities they regulate. The evolution of hormones and gene families is also covered both in the text and in online ancillaries. Users will find simple and visual ways to learn key molecular information. Chapters and online ancillary resources integrate additional sections, providing a comparative molecular, functional, and evolutionary consideration. - Provides the only single resource available with concise, yet informative descriptions of hormones in vertebrates, invertebrates, and plants - Presents hormones in groups according to their origin, so that readers can easily understand their inter-relation - Includes comparative information on the structures and functions of hormones enabling readers to understand both general and specific actions in and across species - Ancillary website hosts additional information, including sequence data, comparative data, figures, and tables

Nunn's Applied Respiratory Physiology

Author : John F Nunn
Publisher : Elsevier Health Sciences
ISBN 13 : 1483292053
Total Pages : 681 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Nunn's Applied Respiratory Physiology by : John F Nunn

Download or read book Nunn's Applied Respiratory Physiology written by John F Nunn and published by Elsevier Health Sciences. This book was released on 1993-10-04 with total page 681 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nunn's Applied Respiratory Physiology

Advanced Wound Repair Therapies

Author : David Farrar
Publisher : Elsevier
ISBN 13 : 0857093304
Total Pages : 672 pages
Book Rating : 4.8/5 (57 download)

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Book Synopsis Advanced Wound Repair Therapies by : David Farrar

Download or read book Advanced Wound Repair Therapies written by David Farrar and published by Elsevier. This book was released on 2011-06-21 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wound repair is an important and growing sector of the medical industry with increasingly sophisticated biomaterials and strategies being developed to treat wounds. Advanced wound repair therapies provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds.Part one provides an introduction to chronic wounds, with chapters covering dysfunctional wound healing, scarring and scarless wound healing and monitoring of wounds. Part two covers biomaterial therapies for chronic wounds, including chapters on functional requirements of wound repair biomaterials, polymeric materials for wound dressings and interfacial phenomena in wound healing. In part three, molecular therapies for chronic wounds are discussed, with chapters on topics such as drug delivery, molecular and gene therapies and antimicrobial dressings. Part four focuses on biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair. Finally, part five covers physical stimulation therapies for chronic wounds, including electrical stimulation, negative pressure therapy and mechanical debriding devices.With its distinguished editor and international team of contributors, Advanced wound repair therapies is an essential reference for researchers and materials scientists in the wound repair industry, as well as clinicians and those with an academic research interest in the subject. - Provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds - Chapters include the role of micro-organisms and biofilms in dysfunctional wound healing, tissue-biomaterial interaction and electrical stimulation for wound healing - Covers biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair

Cellular and Molecular Biology of the Renin-Angiotensin System

Author : Mohan K. Raizada
Publisher : CRC Press
ISBN 13 : 1351087398
Total Pages : 455 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Cellular and Molecular Biology of the Renin-Angiotensin System by : Mohan K. Raizada

Download or read book Cellular and Molecular Biology of the Renin-Angiotensin System written by Mohan K. Raizada and published by CRC Press. This book was released on 2018-01-18 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Biology of the Renin-Angiotensin System provides the first review and update of the state-of-the-art cellular and molecular aspects of the renin-angiotensin system. The book presents detailed analyses from world experts on each component of this system, including future directions. Topics range from angiotensin II receptor subtypes to processing of renin to the use of transgenic animal models for studying the role of this system in hypertension. Cellular and Molecular Biology of the Renin-Angiotensin System is essential reading for physiologists of the renin-angiotensin system, endocrinologists, cardiovascular specialists, renal physiologists, and neurobiologists.

Textbook of Nephro-Endocrinology

Author : Ajay K. Singh
Publisher : Academic Press
ISBN 13 : 0080920462
Total Pages : 534 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Textbook of Nephro-Endocrinology by : Ajay K. Singh

Download or read book Textbook of Nephro-Endocrinology written by Ajay K. Singh and published by Academic Press. This book was released on 2009-01-12 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism. - Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems - Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference work - Clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field

Vascular Biology of the Placenta

Author : Yuping Wang
Publisher : Biota Publishing
ISBN 13 : 1615047514
Total Pages : 126 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Vascular Biology of the Placenta by : Yuping Wang

Download or read book Vascular Biology of the Placenta written by Yuping Wang and published by Biota Publishing. This book was released on 2017-06-23 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.

Handbook of Biologically Active Peptides

Author : Abba Kastin
Publisher : Elsevier
ISBN 13 : 0080463797
Total Pages : 1682 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Handbook of Biologically Active Peptides by : Abba Kastin

Download or read book Handbook of Biologically Active Peptides written by Abba Kastin and published by Elsevier. This book was released on 2011-04-28 with total page 1682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides play a crucial role in many physiological processes including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The Handbook of Biologically Active Peptides presents, for the first time, this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. The Handbook of Biologically Active Peptides is a definitive, all-encompassing reference that will be indispensable for individuals ranging from peptide researchers, to biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and to endocrinologists. Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas with which they would not ordinarily be familiar.*Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas that they would not ordinarily be familiar.*Fascinating relationships described in the book include the presence of some peptides originally found in frog skin that persist in the human human and brain where they can affect food intake and obesity.

Urticaria and Angioedema

Author : Selda Pelin Kartal
Publisher : BoD – Books on Demand
ISBN 13 : 9535131672
Total Pages : 252 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Urticaria and Angioedema by : Selda Pelin Kartal

Download or read book Urticaria and Angioedema written by Selda Pelin Kartal and published by BoD – Books on Demand. This book was released on 2017-05-31 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the latest advances and scientific knowledge from the leading experts in urticaria and angioedema. The book consists of 15 chapters in which urticaria classification, urticaria etiopathogenesis, urticaria clinics, urticarial syndromes, angioedemas, diagnosis, pathogenesis and pathophysiology of urticaria, and treatment options are discussed. This book also emphasizes on the various laboratory tests necessary for urticarias. One chapter of the book is devoted to comorbidities in chronic spontaneous urticaria. Another chapter is related with pathophysiology and treatment of hereditary angioedema. We are grateful to all the contributors and leading experts for their valuable chapters, which provide an in-depth view of all aspects of the content, backed with the most current literature in the field. We hope that this book will provide interesting knowledge and serve as a comprehensive guide to many physicians dealing with urticaria and angioedemas in their clinical practice.

Inflammation, 4 Volume Set

Author : Jean-Marc Cavaillon
Publisher : John Wiley & Sons
ISBN 13 : 3527338993
Total Pages : 1818 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Inflammation, 4 Volume Set by : Jean-Marc Cavaillon

Download or read book Inflammation, 4 Volume Set written by Jean-Marc Cavaillon and published by John Wiley & Sons. This book was released on 2018-02-20 with total page 1818 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dieses Fachbuch erläutert die molekularen Grundlagen von Entzündungen, spannt den Bogen zu Infektionskrankheiten und den Zusammenhang zwischen Entzündungen und chronischen Erkrankungen, behandelt abschließend den Heilungsprozess und zeigt Therapiemöglichkeiten.

Hormones and Transport Systems

Author :
Publisher : Academic Press
ISBN 13 : 0128030283
Total Pages : 584 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Hormones and Transport Systems by :

Download or read book Hormones and Transport Systems written by and published by Academic Press. This book was released on 2015-03-26 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on hormone and transport systems. - Expertise of the contributors - Coverage of a vast array of subjects - In depth current information at the molecular to the clinical levels