Biosynthetic Studies of D-desosamine and Engineered Biosynthesis of Methymycin/pikromycin Analogs Carrying Modified Deoxysugars

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ISBN 13 :
Total Pages : 534 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Biosynthetic Studies of D-desosamine and Engineered Biosynthesis of Methymycin/pikromycin Analogs Carrying Modified Deoxysugars by : Lishan Zhao

Download or read book Biosynthetic Studies of D-desosamine and Engineered Biosynthesis of Methymycin/pikromycin Analogs Carrying Modified Deoxysugars written by Lishan Zhao and published by . This book was released on 2000 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Complex Enzymes in Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins and Carbohydrates

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Publisher : Academic Press
ISBN 13 : 0080923364
Total Pages : 644 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Complex Enzymes in Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins and Carbohydrates by :

Download or read book Complex Enzymes in Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins and Carbohydrates written by and published by Academic Press. This book was released on 2009-04-11 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial natural products have been an important traditional source of valuable antibiotics and other drugs but interest in them waned in the 1990s when big pharma decided that their discovery was no longer cost-effective and concentrated instead on synthetic chemistry as a source of novel compounds, often with disappointing results. Moreover understanding the biosynthesis of complex natural products was frustratingly difficult. With the development of molecular genetic methods to isolate and manipulate the complex microbial enzymes that make natural products, unexpected chemistry has been revealed and interest in the compounds has again flowered. This two-volume treatment of the subject will showcase the most important chemical classes of complex natural products: the peptides, made by the assembly of short chains of amino acid subunits, and the polyketides, assembled from the joining of small carboxylic acids such as acetate and malonate. In both classes, variation in sub-unit structure, number and chemical modification leads to an almost infinite variety of final structures, accounting for the huge importance of the compounds in nature and medicine. Gathers tried and tested methods and techniques from top players in the field Provides an extremely useful reference for the experienced research scientist Covers biosynthesis of Polyketides, Tarpenoids, Aminocoumarins and Crabohydrates

Dissertation Abstracts International

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Publisher :
ISBN 13 :
Total Pages : 856 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Dissertation Abstracts International by :

Download or read book Dissertation Abstracts International written by and published by . This book was released on 2000 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Directory of Graduate Research

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ISBN 13 :
Total Pages : 1850 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Directory of Graduate Research by :

Download or read book Directory of Graduate Research written by and published by . This book was released on 2001 with total page 1850 pages. Available in PDF, EPUB and Kindle. Book excerpt: Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.

Biocombinatorial Approaches for Drug Finding

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Publisher : Springer Science & Business Media
ISBN 13 : 9783540220923
Total Pages : 310 pages
Book Rating : 4.2/5 (29 download)

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Book Synopsis Biocombinatorial Approaches for Drug Finding by : W. Wohlleben

Download or read book Biocombinatorial Approaches for Drug Finding written by W. Wohlleben and published by Springer Science & Business Media. This book was released on 2004-11-29 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome- and proteome-based research is generating a significant increase in the number of available drug targets. Correspondingly there is an increasing need for novel, diverse compounds, particularly based on natural compounds, as screening resource. The purpose of the Ernst Schering Research Foundation Workshop 51 was to provide a forum for an open exchange on perspectives and limitations of biocombinatorial synthesis and the significance of this technology for future drug discovery in light of this challenge. Experts from academia and industry provided contributions covering: the significance of natural compounds for state-of-the-art drug discovery; the underlying basic principle for the biosynthesis of highly complex compounds; and the scope and limitations of combinatorial biosynthesis regarding formation, identification, optimisation, isolation and manufacturing of novel biologically active entities.

Microbial Resources

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Publisher : Academic Press
ISBN 13 : 012805140X
Total Pages : 356 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Microbial Resources by : Ipek Kurtboke

Download or read book Microbial Resources written by Ipek Kurtboke and published by Academic Press. This book was released on 2017-03-31 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Resources: From Functional Existence in Nature to Applications provides an exciting interdisciplinary journey through the rapidly developing field of microbial resources, including relationships to aspects of microbiology. Covers the functional existence of microorganisms in nature, as well as the transfer of this knowledge for industrial and other applications. Examines the economic perspective of revealing the potential value of microbial material and figuring it into socio-economic value; legal perspectives; and how to organize a fair allotment of socio-economic benefits to all stakeholders who have effectively contributed to the preservation, study, and exploitation of microbiological material. - Covers aspects of foundational information related to microbiology, microbial ecology, and diversity, as well as new advances in microbial genomics - Provides information on the utilization of microbial resources in biotechnology - Covers legislative issues and related law in biodiscovery - Fills a need for a very broad audience and is a good resource for microbiologists seeking to know the extent of microbiology approaches, the policies associated with microbiology, and potential career paths for researchers - Has significant added value due to the inclusion of comprehensive coverage of the biology, ecology, biochemistry and international legislation surrounding these applications

Enzymes

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Publisher : John Wiley & Sons
ISBN 13 : 0471461857
Total Pages : 416 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Enzymes by : Robert A. Copeland

Download or read book Enzymes written by Robert A. Copeland and published by John Wiley & Sons. This book was released on 2004-04-07 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully updated and expanded-a solid foundation for understandingexperimental enzymology. This practical, up-to-date survey is designed for a broadspectrum of biological and chemical scientists who are beginning todelve into modern enzymology. Enzymes, Second Editionexplains the structural complexities of proteins and enzymes andthe mechanisms by which enzymes perform their catalytic functions.The book provides illustrative examples from the contemporaryliterature to guide the reader through concepts and data analysisprocedures. Clear, well-written descriptions simplify the complexmathematical treatment of enzyme kinetic data, and numerouscitations at the end of each chapter enable the reader to accessthe primary literature and more in-depth treatments of specifictopics. This Second Edition of Enzymes: A Practical Introductionto Structure, Mechanism, and Data Analysis features refinedand expanded coverage of many concepts, while retaining theintroductory nature of the book. Important new featuresinclude: A new chapter on protein-ligand binding equilibria Expanded coverage of chemical mechanisms in enzyme catalysisand experimental measurements of enzyme activity Updated and refined discussions of enzyme inhibitors andmultiple substrate reactions Coverage of current practical applications to the study ofenzymology Supplemented with appendices providing contact information forsuppliers of reagents and equipment for enzyme studies, as well asa survey of useful Internet sites and computer software forenzymatic data analysis, Enzymes, Second Edition isthe ultimate practical guide for scientists and students inbiochemical, pharmaceutical, biotechnical, medicinal, andagricultural/food-related research.

Enzymes in Synthetic Biology

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Publisher : Academic Press
ISBN 13 : 0128151498
Total Pages : 460 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Enzymes in Synthetic Biology by :

Download or read book Enzymes in Synthetic Biology written by and published by Academic Press. This book was released on 2018-08-30 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 608 of the series Methods in Enzymology covers key aspects of enzyme discovery, engineering tools and platforms, and examples of applications in the enzymology of synthetic biology. Detailed methods for laboratory use of enzymes in synthetic biology applications Informative case history examples illustrating how enzyme and metabolic engineering are used to generate new products Emphasises latest developments in laboratory automation for the engineering of biology Covers many aspects of the design, build, test, learn cycle used in synthetic biology

Food Waste to Valuable Resources

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Publisher : Academic Press
ISBN 13 : 0128183543
Total Pages : 464 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Food Waste to Valuable Resources by : Rajesh Banu

Download or read book Food Waste to Valuable Resources written by Rajesh Banu and published by Academic Press. This book was released on 2020-04-28 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food Waste to Valuable Resources: Applications and Management compiles current information pertaining to food waste, placing particular emphasis on the themes of food waste management, biorefineries, valuable specialty products and technoeconomic analysis. Following its introduction, this book explores new valuable resource technologies, the bioeconomy, the technoeconomical evaluation of food-waste-based biorefineries, and the policies and regulations related to a food-waste-based economy. It is an ideal reference for researchers and industry professionals working in the areas of food waste valorization, food science and technology, food producers, policymakers and NGOs, environmental technologists, environmental engineers, and students studying environmental engineering, food science, and more. - Presents recent advances, trends and challenges related to food waste valorization - Contains invaluable knowledge on of food waste management, biorefineries, valuable specialty products and technoeconomic analysis - Highlights modern advances and applications of food waste bioresources in various products' recovery

Anthracycline Chemistry and Biology II

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Publisher : Springer Science & Business Media
ISBN 13 : 3540758127
Total Pages : 231 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Anthracycline Chemistry and Biology II by : Karsten Krohn

Download or read book Anthracycline Chemistry and Biology II written by Karsten Krohn and published by Springer Science & Business Media. This book was released on 2008-07-11 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by the world renowned experts. The series is still valid and useful after five or ten years. More information as well as the electronic version of the whole content is available at: springerlink.com.

Carbohydrate-based Drug Discovery, 2 Volume Set

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Publisher : John Wiley & Sons
ISBN 13 : 9783527306329
Total Pages : 520 pages
Book Rating : 4.3/5 (63 download)

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Book Synopsis Carbohydrate-based Drug Discovery, 2 Volume Set by : Chi-Huey Wong

Download or read book Carbohydrate-based Drug Discovery, 2 Volume Set written by Chi-Huey Wong and published by John Wiley & Sons. This book was released on 2003-10-17 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Die Suche nach Medikamenten mit neuen oder verbesserten Eigenschaften hat das Interesse am pharmazeutischen Potenzial von Kohlenhydraten enorm verstärkt. Dies gilt insbesondere für die Entwicklung von Antibiotika, Impfstoffen und Anti-Krebs-Mitteln. Carbohydrate-based Drug Discovery stellt mit mehr als 50 Beiträgen der weltweit führenden Experten die neuesten Entwicklungen in der Kohlenhydrat- und Biochemie vor. Dabei liegt der Schwerpunkt der Darstellung auf der pharmazeutischen Anwendung. In jüngster Zeit sind wirksame, auf Kohlenhydraten basierende Medikamente gegen HIV, Grippe, Epilepsie, Diabetes und Krebs auf den Markt gekommen bzw. werden in Studien klinisch erprobt. Doch das gesamte Potenzial dieser Substanzklasse kann man bislang wohl nur erahnen. Die pharmazeutische Industrie investiert bereits große Summen in die Forschung und Entwicklung. So kommt dieses Handbuch genau zur richtigen Zeit. Umfassend und kompetent behandelt es den gesamten Bereich der Kohlenhydratchemie. Es führt ein in die chemische Synthese, in Biosynthese und Metabolismus und informiert über die Analyse und die zellulären Funktionen von Kohlenhydraten. Einen weiteren Schwerpunkt bildet die Entwicklung von Medikamenten auf Kohlenhydrat-Basis, wie z.B. synthetischer Impfstoffe oder Thrombosemittel auf Basis synthetischer Oligosaccharide. Erschlossen wird das mit einem umfangreichen bibliographischen Anhang versehene Werk durch einen thematischen Index. Sein Herausgeber, Chi-Huey Wong, hat bereits mehrere internationale Preise für sein wissenschaftliches Werk erhalten, darunter den "Presidential Award" und den "Presidential Young Investigator Award".

Genetic Manipulation of Streptomyces

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Publisher :
ISBN 13 :
Total Pages : 378 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genetic Manipulation of Streptomyces by : D. A. Hopwood

Download or read book Genetic Manipulation of Streptomyces written by D. A. Hopwood and published by . This book was released on 1985 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Therapeutic, Probiotic, and Unconventional Foods

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Publisher : Academic Press
ISBN 13 : 0128146265
Total Pages : 488 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Therapeutic, Probiotic, and Unconventional Foods by : Alexandru Mihai Grumezescu

Download or read book Therapeutic, Probiotic, and Unconventional Foods written by Alexandru Mihai Grumezescu and published by Academic Press. This book was released on 2018-04-18 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic, Probiotic and Unconventional Foods compiles the most recent, interesting and innovative research on unconventional and therapeutic foods, highlighting their role in improving health and life quality, their implications on safety, and their industrial and economic impact. The book focuses on probiotic foods, addressing the benefits and challenges associated with probiotic and prebiotic use. It then explores the most recently investigated and well-recognized nutraceutical and medicinal foods and the food products and ingredients that have both an impact on human health and a potential therapeutic effect. The third and final section explores unconventional foods and discusses intriguing and debated foods and food sources. While research has been conducted on the beneficial biological effects of probiotics and therapeutic food, the use of these foods remains controversial. To overcome the suspicion of the use of alternative, homeopathic and traditional products as therapy, this book reveals and discusses the most recent and scientifically sound and confirmed aspects of the research. - Compiles the most recent, interesting and innovative research on unconventional and therapeutic foods - Highlights the role of unconventional and therapeutic foods in improving health and life quality - Discusses the implications of unconventional and therapeutic foods on safety - Presents the industrial and economic impact of unconventional and therapeutic foods

The Polyketide Metabolites

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Publisher : Ellis Horwood
ISBN 13 :
Total Pages : 184 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis The Polyketide Metabolites by : David O'Hagan

Download or read book The Polyketide Metabolites written by David O'Hagan and published by Ellis Horwood. This book was released on 1991 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Carbohydrates in Drug Discovery and Development

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Publisher : Elsevier
ISBN 13 : 0128166754
Total Pages : 714 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Carbohydrates in Drug Discovery and Development by : Vinod K. Tiwari

Download or read book Carbohydrates in Drug Discovery and Development written by Vinod K. Tiwari and published by Elsevier. This book was released on 2020-08-01 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrates in Drug Discovery and Development: Synthesis and Applications examines recent and notable developments in the synthesis, biology, therapeutic, and biomedical applications of carbohydrates, which is considered to be a highly promising area of research in the field of medicinal chemistry. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell surface recognition formulate the carbohydrate systems to be an exceedingly considerable scaffold for the development of new chemical entities of pharmacological importance. In addition to their easy accessibility, high functionality and chiralpool characteristics are the few additional fascinating structural features of carbohydrates, which further enhance their utilities and thus they have been able to attract chemists and biologists toward harnessing these properties for the past several decades.This book covers an advanced aspect of carbohydrate-based molecular scaffolding, starting with a general introduction followed by a detailed discussion about the impact of diverse carbohydrate-containing molecules of great therapeutic values and their impact on drug discovery and development. The topics covered in this book include the significance of heparin mimetics as the possible tools for the modulation of biology and therapy, chemistry and bioactivities of C-glycosylated compounds, inositols, iminosugars, KDO, sialic acids, glycohybrids, macrocycles, plant oligosaccharides, anti-bacterial and anti-cancer vaccines, antibiotics, and more.

Acute Care Handbook for Physical Therapists - E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323227538
Total Pages : 529 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Acute Care Handbook for Physical Therapists - E-Book by : Jaime C. Paz

Download or read book Acute Care Handbook for Physical Therapists - E-Book written by Jaime C. Paz and published by Elsevier Health Sciences. This book was released on 2013-10-04 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: - NEW! Restructured table of contents helps you quickly locate information. - NEW! Language from the International Classification of Functioning, Disability, and Health (ICF) model adopted by the American Physical Therapy Association increases your familiarity with terminology. - NEW! New intervention algorithms along with existing algorithms break clinical decision-making into individual steps and sharpens your on-the-spot critical-thinking skills. - NEW! A quick-reference appendix covering abbreviations commonly found in the acute care environment supplies the translation tools you need, while flagging any abbreviations that may be harmful to the patient.

Natural Product Biosynthesis by Microorganisms and Plants

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Publisher : Academic Press
ISBN 13 : 012394290X
Total Pages : 488 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Natural Product Biosynthesis by Microorganisms and Plants by : D. A. Hopwood

Download or read book Natural Product Biosynthesis by Microorganisms and Plants written by D. A. Hopwood and published by Academic Press. This book was released on 2012 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation This volume of 'Methods in Enzymology' continues the legacy of this premier serial by containing quality chapters authored by leaders in the field.