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Bioorganic And Enzymatic Catalysis
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Book Synopsis Bioorganic and Enzymatic Catalysis by : Wolf-D. Woggon
Download or read book Bioorganic and Enzymatic Catalysis written by Wolf-D. Woggon and published by John Wiley & Sons. This book was released on 2024-01-03 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioorganic and Enzymatic Catalysis Direct comparison of enzymatic reactions and corresponding catalytic transformations in the laboratory Bioorganic and Enzymatic Catalysis covers the most important enzymatic reactions and related catalytic bioorganic reactions using a new approach: Each enzymatic reaction type is compared with organocatalytic, organometallic and other alternative reactions, allowing the reader to understand catalytic reactions in a much-integrated way. For example, in a chapter that describes aldolases corresponding reactions using catalytic antibodies, organocatalytic reagents and metal complexes are discussed. Written by a well-known expert in the field with more than 30 years of experience in organic and bioorganic chemistry, Bioorganic and Enzymatic Catalysis covers sample topics such as: Enzymatic C-C bond formation using aldolases Claisen-type C-C bond formation involving fatty acid synthases and polyketide synthases Biomimetic cyclisations involving carbenium ions Enzymatic oxidation and C-H activation Dioxygenases and oxidoreductases With its unique approach, Bioorganic and Enzymatic Catalysis is a valuable source of information for professionals and researchers in academia and industry as well as graduate and PhD students working in the fields of organic chemistry, biochemistry, and life sciences.
Book Synopsis The Biorganic Chemistry of Enzymatic Catalysis by : Valerian T. D'Souza
Download or read book The Biorganic Chemistry of Enzymatic Catalysis written by Valerian T. D'Souza and published by CRC Press. This book was released on 1991-12-10 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume grew out of a symposium organized by the students of Professor Myron L. Bender. His research focused on the mechanisms of enzymatic catalysis and was instrumental in showing that enzymes do not possess magical powers to accelerate reactions a trillion times on an average, but follow simple rules of chemistry. A group of scientists who were trained by Bender have contributed some of their work to this book to pay homage to their mentor. The range of topics covered is such that researchers and industry with interest in biological chemistry will gain knowledge from the advances being made in related fields. The book shows organic chemists what advances have taken place in biological chemistry and biochemists will discover how principles of organic chemistry can be applied to reveal the powers of enzymatic catalysis.
Book Synopsis Molecular Design and Bioorganic Catalysis by : C.S. Wilcox
Download or read book Molecular Design and Bioorganic Catalysis written by C.S. Wilcox and published by Springer. This book was released on 2012-02-26 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most active areas of contemporary organic chemistry involves the search for new catalysts that borrow concepts, strategies and even components from enzymes but yet are not found in nature. Such artificial enzymes not only give enormous insights into the mechanisms of enzyme catalysis but also offer the potential for catalyzing a wide range of chemical reactions with no counterpart in nature. Several approaches have been taken in the deVelopment of new catalysts, some based on biological methods and others on synthetic techniques. Site directed mutagenesis has allowed the direct replacement of amino acids in an enzyme with resulting changes in stability, selectivity and mechanism. Recent developments have shown that even non-natural amino acids can be incorporated into proteins and also that enzymes can function effectively in organic solvents. A different biological route to artificial enzymes has exploited the immune system and its ability to generate millions of antibodies to a given antigen. Novel antigens have been designed to mimic the transition states of chemical reactions. Antibodies elicited against these antigens thus contain an active site that is complementary to transition state structure and can potentially catalyze target reactions. A broad range of reactions can now be 6 catalyzed using the method with rate accelerations reaching 10 compared to the control reactions. Protein engineering and catalytic antibodies represent complex solutions to the problem of artificial enzymes. Their complexity is however their principal limitation.
Download or read book Bioorganic Chemistry written by H. Dugas and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Springer Advanced Texts in Chemistry New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical ther modynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases the availability of texts in active research areas should help stimulate the creation of new courses. New York, New York CHARLES R.
Author :Gertz I. Likhtenshtein Publisher :Springer Science & Business Media ISBN 13 :0306481103 Total Pages :239 pages Book Rating :4.3/5 (64 download)
Book Synopsis New Trends in Enzyme Catalysis and Biomimetic Chemical Reactions by : Gertz I. Likhtenshtein
Download or read book New Trends in Enzyme Catalysis and Biomimetic Chemical Reactions written by Gertz I. Likhtenshtein and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book is a view of enzyme catalysis by a physico-chemist with long-term experience in the investigation of structure and action mechanism of biological catalysts. This book is not intended to provide an exhaustive survey of each topic but rather a discussion of their theoretical and experimental background, and recent developments. The literature of enzyme catalysis is so vast and many scientists have made important contribution in the area, that it is impossible in the space allowed for this book to give a representative set of references. The author has tried to use reviews, and general principles of articles. He apologizes to those he has not been able to include. . ... The monograph is intended for scientists working on enzyme catalysis and adjacent areas such as chemical modeling of biological processes, homogeneous catalysis, biomedical research and biotechnology. The book can be use as a subsidiary manual for instructors, graduate and undergraduate students of university biochemistry and chemistry departments."--Pages ix-x.
Book Synopsis The Organic Chemistry of Enzyme-catalyzed Reactions by : Richard B. Silverman
Download or read book The Organic Chemistry of Enzyme-catalyzed Reactions written by Richard B. Silverman and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written for advanced undergraduate and graduate students as well as professionals in organic and medicinal chemistry, this text illuminates the black box of enzyme-catalyzed reactions by showing how enzymes are simply highly efficient organic chemists. Enzyme-catalyzed reactions are essential for the design of enzyme inhibitors in the pharmaceutical and agricultural industries, and of growing importance for process development in the chemical and biotechnology industries. Following a general introduction to the role of enzymes as catalysts, each chapter describes the organic transformations. The compilation includes a number of drawings to illustrate structures and mechanisms, and focuses on one of two examples of enzymes that catalyze the particular chemistry for that transformation.
Book Synopsis Bioorganic Chemistry in Healthcare and Technology by : Upendra K. Pandit
Download or read book Bioorganic Chemistry in Healthcare and Technology written by Upendra K. Pandit and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: In current thinking, Bioorganic Chemistry may be defined as the area of chemistry which lies in the border region between organic chemistry and biology and which describes and analyzes biological phenomena in terms of detailed molecular structures and molecular mechanisms. This molecular-level view of biological processes is not only essential to their fuller understanding but also serves as the platform for the application of the principles of such processes to areas of health care and technology. The objective of the ASI workshop on " Bioorganic Chemistry in Healthcare and Technology", held in the Hengelhoef Congress Centre in Houthalen-Helchteren, Belgium, from September 18-21, 1990, was to bring together most of the international experts in the field to discuss the current developments and new trends in bioorganic chemistry, especially in relation to the selected theme. The book presents nineteen invited plenary and session lectures and eighteen posters. These cover areas of (i) molecular design of therapeutic and agronomical agents based npon mechanistic rationale or drug-receptor interactions, (ii) production of substances of commercial value via combined organic chemical and bio-chemical methodologies, (iii) fundamental studies on the molecular mechanisms of enzymes and (iv) the evolution of conceptually new molecular systems which are programmed to execute specific recognition and/or catalytic functions. An abstracted version of the plenary discussion held at the end of the workshop is also included. We feel confident that the subject matter of this book will be of interest to a broad group of chemists engaged in academic or industrial research.
Book Synopsis Bioorganic Chemistry by : Hermann Dugas
Download or read book Bioorganic Chemistry written by Hermann Dugas and published by Boom Koninklijke Uitgevers. This book was released on 1999-08-27 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: This widely-praised textbook is particularly suited for advanced undergraduates or graduates in chemistry, biochemistry, medicinal chemistry, and pharmacology. The third edition has been substantially revised to reflect new research in the field, and features a major new chapter on self-assembly, auto-organization, and molecular devices. The outstanding figures remain a highlight of the book, and were described in an earlier edition as "the best I've seen for showing the organic chemistry of biomolecules." (Quart. Rev. Biol.)
Book Synopsis Enzyme Catalysis in Organic Synthesis, 3 Volume Set by : Karlheinz Drauz
Download or read book Enzyme Catalysis in Organic Synthesis, 3 Volume Set written by Karlheinz Drauz and published by John Wiley & Sons. This book was released on 2012-03-26 with total page 2143 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive three-volume set is the standard reference in the field of organic synthesis, catalysis and biocatalysis. Edited by a highly experienced and highly knowledgeable team with a tremendous amount of experience in this field and its applications, this edition retains the successful concept of past editions, while the contents are very much focused on new developments in the field. All the techniques described are directly transferable from the lab to the industrial scale, making for a very application-oriented approach. A must for all chemists and biotechnologists.
Book Synopsis Bioorganic Chemistry: Enzyme action by : Eugene E. Van Tamelen
Download or read book Bioorganic Chemistry: Enzyme action written by Eugene E. Van Tamelen and published by . This book was released on 1977 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Frontiers of Bioorganic Chemistry and Molecular Biology by : S. N. Ananchenko
Download or read book Frontiers of Bioorganic Chemistry and Molecular Biology written by S. N. Ananchenko and published by Elsevier. This book was released on 2017-05-04 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers of Bioorganic Chemistry and Molecular Biology covers the proceedings of the International Symposium on Frontiers of Bioorganic Chemistry and Molecular Biology, held in Moscow and Tashkent, USSR on September 25-October 2, 1978. This symposium is devoted to a discussion of the physico-chemical basis of life processes. This book contains 56 chapters, and reflects the results in the study of peptides and proteins, nucleic acids, polysaccharides, and other biopolymers. Other chapters deal with the study of low molecular regulators, including steroids, alkaloids, and antibiotics. This book also includes discussion of the achievements in the study of genetic structures and of cellular protein synthesizing systems of the molecular basis of enzymic catalysis and of bioenergetic processes. This book will be of value to biochemists and molecular biologists.
Book Synopsis Microreactors in Organic Chemistry and Catalysis by : Thomas Wirth
Download or read book Microreactors in Organic Chemistry and Catalysis written by Thomas Wirth and published by John Wiley & Sons. This book was released on 2013-02-22 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the second edition of 'Microreactors in Organic Chemistry and Catalysis' all chapters have been revised and updated to reflect the latest developments in this rapidly developing field. This new edition has 60% more content, and it remains a comprehensive publication covering most aspects of the topic. The use of microreactors in homogeneous, heterogeneous as well as biphasic reactions is covered in the main part of the book, together with catalytic, bioorganic and automation approaches. The initial chapters also provide a solid physical chemistry background on fluidics in microdevices. Finally, a chapter on industrial applications and developments covers recent progress in process chemistry. An excellent reference for beginners and experts alike.
Book Synopsis Enzymatic Reaction Mechanisms by : Perry A. Frey
Download or read book Enzymatic Reaction Mechanisms written by Perry A. Frey and published by Oxford University Press. This book was released on 2007-01-27 with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt: Books dealing with the mechanisms of enzymatic reactions were written a generation ago. They included volumes entitled Bioorganic Mechanisms, I and II by T.C. Bruice and S.J. Benkovic, published in 1965, the volume entitled Catalysis in Chemistry and Enzymology by W.P. Jencks in 1969, and the volume entitled Enzymatic Reaction Mechanisms by C.T. Walsh in 1979. The Walsh book was based on the course taught by W.P. Jencks and R.H. Abeles at Brandeis University in the 1960's and 1970's. By the late 1970's, much more could be included about the structures of enzymes and the kinetics and mechanisms of enzymatic reactions themselves, and less emphasis was placed on chemical models. Walshs book was widely used in courses on enzymatic mechanisms for many years. Much has happened in the field of mechanistic enzymology in the past 15 to 20 years. Walshs book is both out-of-date and out-of-focus in todays world of enzymatic mechanisms. There is no longer a single volume or a small collection of volumes to which students can be directed to obtain a clear understanding of the state of knowledge regarding the chemicals mechanisms by which enzymes catalyze biological reactions. There is no single volume to which medicinal chemists and biotechnologists can refer on the subject of enzymatic mechanisms. Practitioners in the field have recognized a need for a new book on enzymatic mechanisms for more than ten years, and several, including Walsh, have considered undertaking to modernize Walshs book. However, these good intentions have been abandoned for one reason or another. The great size of the knowledge base in mechanistic enzymology has been a deterrent. It seems too large a subject for a single author, and it is difficult for several authors to coordinate their work to mutual satisfaction. This text by Perry A. Frey and Adrian D. Hegeman accomplishes this feat, producing the long-awaited replacement for Walshs classic text.
Download or read book Bioorganic Chemistry Frontiers written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. K. Kano: Selectivities of Applied Chemistry 2. A. Pl}ckthun: Antibody Engineering to Study Protein-Ligand Interactions and Catalysis: The Phosphorylcholine Binding Antibodies 3. M.W. Hosseini: Supramolecular Catalysis of Phosphoryl Transfer Processes 4. G. von Kiedrowski: Minimal Replicator Theory II: Parabolic versus ExponentialGrowth 5. A. Bacher, W. Eisenreich, K. Kis, R. Ladenstein, G. Richter, J. Scheuring, S. Weinkauf: Biosynthesis of Flavins 6. C.L. Hannon, E.V.Anslyn: The Guanidinium Group: Its Biological Role and Synthetic Analogs.
Book Synopsis Multi-Step Enzyme Catalysis by : Eduardo Garcia-Junceda
Download or read book Multi-Step Enzyme Catalysis written by Eduardo Garcia-Junceda and published by John Wiley & Sons. This book was released on 2008-11-21 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive coverage of this unique and interdisciplinary field provides a complete overview, covering such topics as chemoenzymatic synthesis, microbial production of DNA building blocks, asymmetric transformations by coupled enzymes and much more. By combining enzymatic and synthetic organic steps, the use of multi-enzyme complexes and other techniques opens the door to reactions hitherto unknown, making this monograph of great interest to biochemists, organic chemists, and chemists working with/on organometallics, as well as catalytic chemists, biotechnologists, and those working in the pharmaceutical and fine chemical industries.
Book Synopsis Bioorganic Synthesis by : Gunter E. Jeromin
Download or read book Bioorganic Synthesis written by Gunter E. Jeromin and published by Wiley-VCH. This book was released on 2009-02-01 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at students and junior researchers, this comprehensive introduction to organic synthesis with biocatalysts contains a wealth of knowledge not found in any standard chemistry textbook. Ideal for coursework, including lab courses, in a one-semester course of bioorganic or organic synthesis, the book is divided into two parts. An introductory section covers the fundamentals of enzymatic catalysis and the general procedures of using enzymes in the organic-chemical laboratory, while the practical second part contains detailed protocols for more than 50 enzmye-catalysed organic syntheses. Each of the protocols has been thoroughly tested in the authors' laboratories and comes with a complete description, including equipment list, expected yield, and safety considerations. The text is rounded off by descriptions and supplier information for all commonly used enzymes, enabling even those chemists without prior experience to start working immediately. With its broad coverage of biocatalytic reactions, this textbook is also perfectly suited for biotechnologists or chemical engineers in the booming field of "white biotechnology".
Book Synopsis The Enzyme Catalysis Process by : A. Cooper
Download or read book The Enzyme Catalysis Process written by A. Cooper and published by Springer Science & Business Media. This book was released on 2013-12-11 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents the proceedings of a NATO Advanced Studies Instituteheld near Barga (Italy), July 11-23, 1988, involving over 90 participants from more than twelve countries of Europe, North America and elsewhere. It was not our intention at this meeting to present a complete up-to-the-minute review of current research in enzyme catalysis but t·ather, in accord wi th the intended spiri t of NATO ASis, to gi ve an opportunity for advanced students and researchers in a wide variety of disciplines to meet tagether and study the problern from different points of view. Hence the lectures cover topics rauging from the purely theoretical aspects of chemical reaction kinetics in condensed matter through practical experimental approaches to enzyme structure, dynamics and mechanism, including the new experimental opportunities arising from genetic engineering techniques. Our approachwas unashamedly physical, both because the more biochemical aspects of enzymology are amply covered elsewhere and because progress in our understanding and application of the molecular basis of enzymic processes must ultimately come from advances in physical knowledge. We tried to cover as wide a spectrum as possible, and succeeded in gathering an expert and enthusiastic team of speakers, but there . are some inevitable omissions. In particular, and with hindsight, our discussions might have been enriched by more detailed coverage of general aspects of chemical catalysis - but readers requiring this background should find adequate references herein.
