Biomechanics Of The Aorta

Download Biomechanics Of The Aorta full books in PDF, epub, and Kindle. Read online Biomechanics Of The Aorta ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Biomechanics of the Aorta

Author : T. Christian Gasser
Publisher : Elsevier
ISBN 13 : 0323954855
Total Pages : 636 pages
Book Rating : 4.3/5 (239 download)

DOWNLOAD NOW!

Book Synopsis Biomechanics of the Aorta by : T. Christian Gasser

Download or read book Biomechanics of the Aorta written by T. Christian Gasser and published by Elsevier. This book was released on 2024-06-18 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomechanics of the Aorta: Modelling for Patient Care is a holistic analysis of the aorta towards its biomechanical description. The book addresses topics such as physiology, clinical imaging, tissue and blood flow modeling, along with knowledge that is needed in diagnostics, aortic rupture prediction, assist surgical planning, and more. It encompasses a wide range of topics from the basic sciences (Vascular biology, Continuum mechanics, Image analysis) to clinical applications, as well as describing and presenting computational studies and experimental benches to mimic, understand and propose the best treatment of aortic pathologies. The book begins with an introduction to the fundamental aspects of the anatomy, biology and physiopathology of the aorta and proceeds to present the main computational fluid dynamic studies and biomechanical and mechanobiological models developed over the last decade. With approaches, methodologies and findings from contributors all over the world, this new volume in the Biomechanics of Living Organs series will increase understanding of aortic function as well as improve the design of medical devices and clinical interventions, including surgical procedures. Represents a comprehensive means for those involved in the aortic research and the related developments in the industry Introduces the most recent imaging technologies to characterize factors, such as aortic geometry, mechanical properties of the aortic tissue, and the local cellular activity in the vessel wall Synthesizes advances in vascular biomechanics, medical imaging and computational finite element fluid and solid models to increase understanding of aorta function

Biomechanics and Mechanobiology of Aneurysms

Author : Tim McGloughlin
Publisher : Springer Science & Business Media
ISBN 13 : 3642180957
Total Pages : 432 pages
Book Rating : 4.6/5 (421 download)

DOWNLOAD NOW!

Book Synopsis Biomechanics and Mechanobiology of Aneurysms by : Tim McGloughlin

Download or read book Biomechanics and Mechanobiology of Aneurysms written by Tim McGloughlin and published by Springer Science & Business Media. This book was released on 2011-09-15 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular disease is the leading cause of morbidity and premature death of modern era medicine. It is estimated that approximately 81 million people in the United States (US) currently have one or more of the many forms of cardiovascular disease, resulting in 1 in every 2.8 deaths, or 900,000 deaths per year. 40% of all deaths in Europe are a result of cardiovascular disease in people under the age of 75. Aneurysms form a significant portion of these cardiovascular related deaths and are defined as a permanent and irreversible localised dilation of a blood vessel greater than 50% of its normal diameter. Although aneurysms can form in any blood vessel, the more lethal aneurysms develop in the cranial arteries, and in the thoracic aorta and abdominal aorta. Frequently aneurysms are undetected and if left untreated may eventually expand until rupture with very high levels of morbidity and mortality. The biomechanics and mechanobiology of aneursymal diseases are not fully understood and this monograph aims to provide new insights into aneurysm aetiology and behavior based on the most recent biomechanics research related to this important topic. The contributors to this volume bring together a unique blend of expertise in experimental, computational and tissue biomechanics relating to aneurysm behavior and enable the reader to gain a fresh understanding of key factors influencing aneurysm behavior and treatment. Biological risk factors such as tobacco smoking, sex, age, hypertension, family history and mechanobiological risk factors such as aneurysm geometry and shape as well as mechanical properties of the diseased tissues are considered in detail as are many of the diagnostic and treatment options.

Calcific Aortic Valve Disease

Author : Elena Aikawa
Publisher : BoD – Books on Demand
ISBN 13 : 9535111507
Total Pages : 544 pages
Book Rating : 4.5/5 (351 download)

DOWNLOAD NOW!

Book Synopsis Calcific Aortic Valve Disease by : Elena Aikawa

Download or read book Calcific Aortic Valve Disease written by Elena Aikawa and published by BoD – Books on Demand. This book was released on 2013-06-12 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.

Biomechanics of Soft Tissue in Cardiovascular Systems

Author : Gerhard A. Holzapfel
Publisher : Springer
ISBN 13 : 370912736X
Total Pages : 348 pages
Book Rating : 4.7/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Biomechanics of Soft Tissue in Cardiovascular Systems by : Gerhard A. Holzapfel

Download or read book Biomechanics of Soft Tissue in Cardiovascular Systems written by Gerhard A. Holzapfel and published by Springer. This book was released on 2014-05-04 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is written by leading experts in the field presenting an up-to-date view of the subject matter in a didactically sound manner. It presents a review of the current knowledge of the behaviour of soft tissues in the cardiovascular system under mechanical loads, and the importance of constitutive laws in understanding the underlying mechanics is highlighted. Cells are also described together with arteries, tendons and ligaments, heart, and other biological tissues of current research interest in biomechanics. This includes experimental, continuum mechanical and computational perspectives, with the emphasis on nonlinear behaviour, and the simulation of mechanical procedures such as balloon angioplasty.

Biomechanics and Biochemistry of the Aorta in Chronic Aortic Dissection

Author : Phakakorn Panpho
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (125 download)

DOWNLOAD NOW!

Book Synopsis Biomechanics and Biochemistry of the Aorta in Chronic Aortic Dissection by : Phakakorn Panpho

Download or read book Biomechanics and Biochemistry of the Aorta in Chronic Aortic Dissection written by Phakakorn Panpho and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomechanical Systems Technology

Author : Cornelius T. Leondes
Publisher : World Scientific
ISBN 13 : 9812771379
Total Pages : 278 pages
Book Rating : 4.8/5 (127 download)

DOWNLOAD NOW!

Book Synopsis Biomechanical Systems Technology by : Cornelius T. Leondes

Download or read book Biomechanical Systems Technology written by Cornelius T. Leondes and published by World Scientific. This book was released on 2007 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of rapid developments in computer technology and computational techniques, advances in a wide spectrum of technologies, coupled with cross-disciplinary pursuits between technology and its application to human body processes, the field of biomechanics continues to evolve. Many areas of significant progress include dynamics of musculoskeletal systems, mechanics of hard and soft tissues, mechanics of bone remodeling, mechanics of blood and air flow, flow-prosthesis interfaces, mechanics of impact, dynamics of man-machine interaction, and more. Thus, the great breadth and significance of the field in the international scene require a well integrated set of volumes to provide a complete coverage of the exciting subject of biomechanical systems technology. World-renowned contributors tackle the latest technologies in an in-depth and readable manner. . Sample Chapter(s). Chapter 1: A Simulation Study of Hemodynamic Benefits and Optimal Control of Axial Flow Pump-Based Left Ventricular Assist. Contents: Techniques in Visualization and Evaluation of the In Vivo Microcirculation (S Ichioka); Analyzing Cardiac Biomechanics by Heart Sound (A Voss et al.); Numerical and Experimental Techniques for the Study of Biomechanics in the Arterial System (T P O''Brien et al.); and many other papers. Readership: Academics, researchers and postgraduate students in anatomy, cardiology, orthopaedic, biomechanics and surgery.

Cardiovascular Biomechanics

Author : Peter R. Hoskins
Publisher : Springer
ISBN 13 : 3319464078
Total Pages : 462 pages
Book Rating : 4.3/5 (194 download)

DOWNLOAD NOW!

Book Synopsis Cardiovascular Biomechanics by : Peter R. Hoskins

Download or read book Cardiovascular Biomechanics written by Peter R. Hoskins and published by Springer. This book was released on 2017-02-16 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. With a focus on explaining the underlying principles, this book examines the physiology and mechanics of circulation, mechanobiology and the biomechanics of different components of the cardiovascular system, in-vivo techniques, in-vitro techniques, and the medical applications of this research. Written for undergraduate and postgraduate students and including sample problems at the end of each chapter, this interdisciplinary text provides an essential introduction to the topic. It is also an ideal reference text for researchers and clinical practitioners, and will benefit a wide range of students and researchers including engineers, physicists, biologists and clinicians who are interested in the area of cardiovascular biomechanics.

Biomechanics of Human Ascending Aorta and Aneurysm Rupture Risk Assessment

Author : Siyu Lin
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (138 download)

DOWNLOAD NOW!

Book Synopsis Biomechanics of Human Ascending Aorta and Aneurysm Rupture Risk Assessment by : Siyu Lin

Download or read book Biomechanics of Human Ascending Aorta and Aneurysm Rupture Risk Assessment written by Siyu Lin and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ascending aortic aneurysms (AsAA) and aortic dissections are life-threatening cardiovascular diseases. The main criteria for determining surgical intervention of AsAA are the maximum diameter or the increasing annual rate of the aneurysm. The mortality of the untreated aortic dissection can be 21% to 74%, depending on the delay of hospital admission.Our study aims to characterize the biomechanical properties of the ascending aorta and propose a patient-specific approach to assess the risks of rupture. The purpose of this PhD work is multifold.On the one hand, biaxial tensile tests were performed on AsAA samples obtained from one hundred patients with surgery of AsAA. The impact on the different characteristics and risks was evaluated and cross-compared. We have shown that the risk factors of gender, age, diameter, and aortic valve disorders have a major impact on the stiffness of AsAA. On the other hand, eleven acute type A aortic dissection samples were collected. We have confirmed that the adventitia shows a significant stiffness than the intimomedial layer. Meanwhile, a rare case of AsAA associated with the quadricuspid aortic valve displays similar biomechanical properties to AsAA associated with the bicuspid aortic valve than with the tricuspid aortic valve. In order to make synthetic modeling from 3D printed aorta in 4D flow magnetic resonance imaging (MRI) study, three three-dimensional printable materials were tested to compare with an undilated aortic wall. The biomechanical properties of the 50 SH (shore stiffness) RGD450+TangoPlus is the most aorta-alike material.To conclude, from our result from one hundred patients, gender, age, diameter, and aortic valve disorders are the key to aortic stiffness.

Biomechanics of Ascending Aortic Aneurysms

Author : Alexander Emmott
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (18 download)

DOWNLOAD NOW!

Book Synopsis Biomechanics of Ascending Aortic Aneurysms by : Alexander Emmott

Download or read book Biomechanics of Ascending Aortic Aneurysms written by Alexander Emmott and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "The aorta is the largest artery in the body and serves as the conduit for systemic blood flow from the heart. Its central property is its passive elastic behaviour that converts fluid energy to elastic potential during systole and subsequently returns that stored potential to maintain systemic circulation during diastole. With disease the pathological remodelling of the wall can result in an impairment of its elastic function, particularly in the case of an aortic aneurysm. If left unrepaired, aortic aneurysms carry significant risk of tearing and often result in death or serious disability. Clinical guidelines for surgical intervention are based on aortic diameter thresholds, but unfortunately these criteria are insufficient and an estimated 40% of dissection and rupture cases occur at diameters below the surgical guidelines. Aortic diameter criteria do not fully relay the risk that elastic impairment and pathological remodelling contribute to dissection or rupture. Herein, this thesis tested the hypothesis that the elastic or mechanical properties of the aortic wall can be used as a marker of ascending aortic dysfunction and contribute added information beyond size to identify at-risk patients. In this work we used transesophageal echocardiography, an application of ultrasound imaging to the heart and great vessels, to assess the mechanical properties of the ascending aorta and subsequently validated this methodology with ex vivo tensile analysis on resected tissue. Specifically, we developed novel in vivo stiffness metrics termed the Cardiac Cycle Pressure Modulus (CCPM) and the Cardiac Cycle Stress Modulus (CCSM) that were compared with aortic wall histology and ex vivo stiffness and energy loss parameters that have been widely reported, previously. This approach was applied globally (i.e., circumference averaged) and regionally at four distinct foci around the aortic circumference. Global CCPM and CCSM were significantly predictive of ex vivo mechanical indices and histopathology and could be used to identify patients with adverse aortic remodelling who did not meet standard surgical criteria of ≥5.5 cm diameter. Regional analysis demonstrated that heterogeneity in CCPM and CCSM increased with medial degeneration creating uneven distribution of physiological stress in the aortic wall. Furthermore, both tensile and compressive strain patterns were observed simultaneously in neighbouring regions of some patients suggesting a more complex physio-mechanical environment than had previously been appreciated. Ultimately, this work proposes a novel assessment technique to follow patients with ascending aortic aneurysms that may provide a crucial added dimension to surgical management of patients." --

Vascular Biomechanics

Author : T. Christian Gasser
Publisher : Springer Nature
ISBN 13 : 3030709663
Total Pages : 622 pages
Book Rating : 4.0/5 (37 download)

DOWNLOAD NOW!

Book Synopsis Vascular Biomechanics by : T. Christian Gasser

Download or read book Vascular Biomechanics written by T. Christian Gasser and published by Springer Nature. This book was released on 2022-02-14 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook serves as a modern introduction to vascular biomechanics and provides the comprehensive overview of the entire vascular system that is needed to run successful vascular biomechanics simulations. It aims to provide the reader with a holistic analysis of the vascular system towards its biomechanical description and includes numerous fully through-calculated examples. Various topics covered include vascular system descriptions, vascular exchange, blood vessel mechanics, vessel tissue characterization, blood flow mechanics, and vascular tissue growth and remodeling. This textbook is ideally suited for students and researchers studying and working in classical and computational vascular biomechanics. The book could also be of interest to developers of vascular devices and experts working with the regulatory approval of biomedical simulations. Follows the principle of “learning by doing” and provides numerous fully through-calculated examples for active learning, immediate recall, and self-examination; Provides a holistic understanding of vascular functioning and the integration of information from different disciplines to enable students to use sophisticated numerical methods to simulate the response of the vascular system; Includes several case studies that integrate the presented material. Case studies address problems, such as the biomechanical rupture risk assessment of Abdominal Aortic Aneurysms, Finite Element analysis of structural and blood flow problems, the computation of wall stress and wall shear stress in the aorta.

Biomechanics

Author : Y.C. Fung
Publisher : Springer Science & Business Media
ISBN 13 : 1475726961
Total Pages : 587 pages
Book Rating : 4.4/5 (757 download)

DOWNLOAD NOW!

Book Synopsis Biomechanics by : Y.C. Fung

Download or read book Biomechanics written by Y.C. Fung and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: The theory of blood circulation is the oldest and most advanced branch of biomechanics, with roots extending back to Huangti and Aristotle, and with contributions from Galileo, Santori, Descartes, Borelli, Harvey, Euler, Hales, Poiseuille, Helmholtz, and many others. It represents a major part of humanity's concept of itself. This book presents selected topics of this great body of ideas from a historical perspective, binding important experiments together with mathematical threads. The objectives and scope of this book remain the same as in the first edition: to present a treatment of circulatory biomechanics from the stand points of engineering, physiology, and medical science, and to develop the subject through a sequence of problems and examples. The name is changed from Biodynamics: Circulation to Biomechanics: Circulation to unify the book with its sister volumes, Biomechanics: Mechanical Properties of Living Tissues, and Biomechanics: Motion, Flow, Stress, and Growth. The major changes made in the new edition are the following: When the first edition went to press in 1984, the question of residual stress in the heart was raised for the first time, and the lung was the only organ analyzed on the basis of solid morphologic data and constitutive equations. The detailed analysis of blood flow in the lung had been done, but the physiological validation experiments had not yet been completed.

The Biomechanics of Ascending Aortic Aneurysms

Author : Evan Wener
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (922 download)

DOWNLOAD NOW!

Book Synopsis The Biomechanics of Ascending Aortic Aneurysms by : Evan Wener

Download or read book The Biomechanics of Ascending Aortic Aneurysms written by Evan Wener and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "An ascending aortic aneurysm is a pathologic enlargement of the ascending portion of the aorta. Comorbidities of dilation include aortic valve disease and connective tissue disorders. If the ascending aorta exceeds a threshold diameter, open heart surgery is recommended. This is a traumatic procedure and the recovery is demanding. As our population ages and with improved technologies to diagnose the disease, the number of cases will increase every year. Understanding the mechanics of ascending aortic tissue will help cardiac surgeons make timely decisions on when to intervene. There are many ways to characterize the mechanical properties of aortic tissue. In this study, we used biaxial and uniaxial tensile testing with an optical tracking system to record the Green-Lagrangian (Green strain) strain. Engineering and true stiffness values were calculated and compared along with patient characteristics. Aortas were classified by valve type as healthy, tricuspid, bicuspid type 1 and bicuspid type 2. The results show that diseased tissue does behave differently than healthy tissue indicating that a local remodeling does occurs to the aortic wall. There are also differences in the mechanics between the types of diseased valves suggesting that valve type also affects the way the aortic wall responds to the disturbed hemodynamic environment. Correlations between stiffness and patient characteristics show that no matter which experimented technique or method of stiffness calculation is used, relationships are generally conserved. The only difference is the magnitude of the elastic modulus. The conclusions drawn from the data would not change whether biaxial or uniaxial experiments were performed. However when comparing engineering and true stiffness, only 7/12 covariances were similar and therefore the conclusions are inconsistent. " --

Surgical Management of Aortic Pathology

Author : Olaf H. Stanger
Publisher : Springer
ISBN 13 : 370914874X
Total Pages : 1223 pages
Book Rating : 4.7/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Surgical Management of Aortic Pathology by : Olaf H. Stanger

Download or read book Surgical Management of Aortic Pathology written by Olaf H. Stanger and published by Springer. This book was released on 2019-04-15 with total page 1223 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book follows the concept of perceiving the entire aorta as one functional organ assuming that all individual pathologies and local interventional procedures affect the up- and downstream segments with consequences for complications and disease progression. Thus any preventive or surgical strategy must recognize the aortic disease in its entirety. The book intends to cover the full spectrum of aortic pathologies, mechanisms and functional interplay. The latest available diagnostic tools and options for surgical treatment are presented by the foremost experts in their field in state-of-the-art reviews. The reader is provided with the most current and comprehensive insight into all fundamental and clinical aspects of aortic disease. All chapters are carefully complemented with figures and illustrations.

Biomechanical Systems

Author : Cornelius T. Leondes
Publisher : CRC Press
ISBN 13 : 9781420049534
Total Pages : 338 pages
Book Rating : 4.0/5 (495 download)

DOWNLOAD NOW!

Book Synopsis Biomechanical Systems by : Cornelius T. Leondes

Download or read book Biomechanical Systems written by Cornelius T. Leondes and published by CRC Press. This book was released on 2000-12-26 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of developments in powerful computer technology, computational techniques, advances in a wide spectrum of diverse technologies, and other advances coupled with cross disciplinary pursuits between technology and its greatly significant applied implications in human body processes, the field of biomechanics is evolving as a broadly significant area. The four volumes of Biomechanical Systems, Techniques, and Applications explore the many areas of significant advances, including dynamics of musculo-skeletal systems; mechanics of hard and soft tissues, muscles, bone remodeling, hard and soft tissue interfaces, blood flow, air flow, flow-prosthesis interfaces, and impact; cardiovascular and respiratory biomechanics; and dynamics of many machine interactions.

Biomechanical Modelling at the Molecular, Cellular and Tissue Levels

Author : Gerhard A. Holzapfel
Publisher : Springer Science & Business Media
ISBN 13 : 3211958754
Total Pages : 351 pages
Book Rating : 4.2/5 (119 download)

DOWNLOAD NOW!

Book Synopsis Biomechanical Modelling at the Molecular, Cellular and Tissue Levels by : Gerhard A. Holzapfel

Download or read book Biomechanical Modelling at the Molecular, Cellular and Tissue Levels written by Gerhard A. Holzapfel and published by Springer Science & Business Media. This book was released on 2009-06-05 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Computational Biomechanics for Medicine

Author : Poul M. F. Nielsen
Publisher : Springer
ISBN 13 : 3319755897
Total Pages : 166 pages
Book Rating : 4.3/5 (197 download)

DOWNLOAD NOW!

Book Synopsis Computational Biomechanics for Medicine by : Poul M. F. Nielsen

Download or read book Computational Biomechanics for Medicine written by Poul M. F. Nielsen and published by Springer. This book was released on 2018-05-14 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume comprises the latest developments in both fundamental science and patient-specific applications, discussing topics such as: cellular mechanics, injury biomechanics, biomechanics of the heart and vascular system, algorithms of computational biomechanics for medical image analysis, and both patient-specific fluid dynamics and solid mechanics simulations. With contributions from researchers world-wide, Computational Biomechanics for Medicine: Measurments, Models, and Predictions provides an opportunity for specialists in the field to present their latest methodologies and advancements.

Cardiovascular Mechanics

Author : Michel R. Labrosse
Publisher : CRC Press
ISBN 13 : 1315280280
Total Pages : 386 pages
Book Rating : 4.3/5 (152 download)

DOWNLOAD NOW!

Book Synopsis Cardiovascular Mechanics by : Michel R. Labrosse

Download or read book Cardiovascular Mechanics written by Michel R. Labrosse and published by CRC Press. This book was released on 2018-09-13 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this book is to illustrate in specific detail how cardiovascular mechanics stands as a common pillar supporting such different clinical successes as drugs for high blood pressure, prosthetic heart valves and coronary artery bypass grafting, among others. This information is conveyed through a comprehensive treatment of the overarching principles and theories that are behind mechanobiological processes, aortic and arterial mechanics, atherosclerosis, blood and microcirculation, hear valve mechanics, as well as medical devices and drugs. Examines all major theoretical and practical aspects of mechanical forces related to the cardiovascular system. Discusses a unique coverage of mechanical changes related to an aging cardiovascular system. Provides an overview of experimental methods in cardiovascular mechanics. Written by world-class researchers from Canada, the US and EU. Extensive references are provided at the end of each chapter to enhance further study. Michel R. Labrosse is the founder of the Cardiovascular Mechanics Laboratory at the University of Ottawa, where he is a full professor within the Department of Mechanical Engineering. He has been an active researcher in academia along with being heavily associated with the University of Ottawa Heart Institute. He has authored or co-authored over 90 refereed communications, and supervised or co-supervised over 40 graduate students and post-docs.