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Author : Eric A. Singer
Publisher : Frontiers Media SA
ISBN 13 : 2889762157
Total Pages : 226 pages
Book Rating : 4.8/5 (897 download)
Download or read book Biomarkers in Genitourinary Cancers: Volume I written by Eric A. Singer and published by Frontiers Media SA. This book was released on 2022-05-25 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Riccardo Tellini
Publisher : Frontiers Media SA
ISBN 13 : 2832505376
Total Pages : 305 pages
Book Rating : 4.8/5 (325 download)
Download or read book Biomarkers in Genitourinary Cancers, Volume II written by Riccardo Tellini and published by Frontiers Media SA. This book was released on 2022-11-14 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Siamak Daneshmand
Publisher : Springer
ISBN 13 : 3319933396
Total Pages : 308 pages
Book Rating : 4.3/5 (199 download)
Download or read book Genitourinary Cancers written by Siamak Daneshmand and published by Springer. This book was released on 2018-08-31 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the most pressing current questions in the management of urologic malignancies. The rapid advances in imaging and molecular markers are placed into a clinical context, with explanation of their effects on prognosis and treatment planning. Similarly, progress in immunotherapy is carefully examined, focusing in particular on the role of immune checkpoint inhibitors in both early- and late-stage urologic malignancies. Looking beyond the improvements in minimally invasive techniques for urologic cancers, the impacts of care coordination pathways and enhanced recovery after surgery protocols are reviewed. Readers will also find enlightening discussion of the decision algorithm for the treatment of early-stage, high-grade bladder cancer, taking into account evidence on the most advanced treatment options and the circumstances in which surgery may need to be expedited. The penultimate chapter discusses the Cancer Genome Atlas project for bladder cancer, and the book closes by considering contemporary medical and surgical management of testicular cancer.
Author : Hui Dai
Publisher : Frontiers Media SA
ISBN 13 : 2832547109
Total Pages : 374 pages
Book Rating : 4.8/5 (325 download)
Download or read book Biomarkers and Immunotherapy for Genitourinary Tumors written by Hui Dai and published by Frontiers Media SA. This book was released on 2024-04-02 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genitourinary tumors consist of a large variety of malignancies located in the urinary and the reproductive systems, mainly including prostate cancer, bladder cancer, and renal tumors. Apart from surgeries, various systemic treatments have been used for the whole-course management of genitourinary tumors, including radiation therapy, chemotherapy, and hormonal therapy. However, the characteristics of progression, metastasis, and drug resistance deriving from tumors require and breed novel treatments. Furthermore, exploring biomarkers of genitourinary tumors at the early stage is also beneficial to strengthen the management of patients with tumors. Additionally, the diagnostic and prognostic value of the potential biomarkers for immunotherapy and combined therapy of genitourinary tumors are underexplored. On the basis of precision treatments, the advent of immune-based therapies, including immune checkpoint inhibitors (ICIs, antibodies targeting PD-L1 /PD-1 and CTLA-4 pathways), tumor vaccines, and other therapies, has extended the scope of treatment modalities. FDA has until now approved the clinical application of immune checkpoint inhibitors in a wide range of diseases including some types of genitourinary tumors, whereas not all patients with genitourinary tumors are suitable for immune-based therapies, therefore, the understanding of its underlying mechanism is key to develop effective treatments based on current ICI-based immunotherapy.
Author : Vincent T. DeVita
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496354214
Total Pages : 2049 pages
Book Rating : 4.4/5 (963 download)
Download or read book Prostate and Other Genitourinary Cancers written by Vincent T. DeVita and published by Lippincott Williams & Wilkins. This book was released on 2016-03-18 with total page 2049 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Prostate and Other Genitourinary Cancers: Cancer: Principles & Practice of Oncology, 10th Edition, offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology practitioners, fellows, and others who need an in-depth understanding of prostate and GU cancer. The print reference gives you the solid, dependable guidance you’ve come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors.
Author : Franco Dammacco
Publisher : Academic Press
ISBN 13 : 0128117869
Total Pages : 718 pages
Book Rating : 4.1/5 (281 download)
Download or read book Oncogenomics written by Franco Dammacco and published by Academic Press. This book was released on 2018-10-30 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oncogenomics: From Basic Research to Precision Medicine offers a thorough survey of precision medicine and its diagnostic and therapeutic applications in oncology. Gathering contributions from leading international researchers in the field, chapters examine recent translational advances in oncogenomic methods and technologies, detailing novel molecular classifications of tumors as well as diagnostic and prognostic biomarkers for various types of cancers including pancreatic, gastrointestinal, breast, hematological, lung, osteotropic, genitourinary, and skin cancers. This book provides a foundation for clinical oncologists, human geneticists, and physicians to develop new targeted cancer treatments and incorporate genomic medicine into clinical practice, with particular attention paid to noninvasive diagnostic techniques such as the liquid biopsy and molecular characterization of solid malignancies. Provides clinical oncologists, human geneticists, physicians, and students with a thorough understanding of current diagnostic and prognostic applications of genomic methods and technologies to a variety of solid malignancies Employs current knowledge in oncogenomics towards developing therapeutic interventions for various cancer types Features a team of internationally recognized researchers and physicians in clinical oncology, oncogenomics and precision medicine
Author : Gary S. Stein
Publisher : John Wiley & Sons
ISBN 13 : 1118962885
Total Pages : 708 pages
Book Rating : 4.1/5 (189 download)
Download or read book Cancer written by Gary S. Stein and published by John Wiley & Sons. This book was released on 2019-09-18 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to recent insights into the genetic and epigenetic parameters of cancer biology and pathology and emerging clinical applications The thoroughly updated second edition of The Biology and Treatment of Cancer, now titled Cancer: Prevention, Early Detection, Treatment and Recovery, goes beyond reviewing the fundamental properties of cancer biology and the relevant issues associated with treatment of the disease. The new edition contains coverage of additional "patient centric" topics and presents cancer biology with selection of topics, facts, and perspectives written in easy-to-understand terms. With contributions from noted experts, the book explores recent advances in the understanding of cancer including breakthroughs in the molecular and cellular basis of cancer and provides strategies for approaching cancer prevention, early detection, and treatment. The authors incorporate recent information on the genetic and epigenetic parameters of cancer biology and pathology with indications of emerging clinical applications. The text offers a unique guide to cancer prevention, early detection, treatment, and recovery for students, caregivers, and most importantly cancer patients. This significant book: Incorporates current insight into the genetic and epigenetic parameters of cancer biology and pathology and information on emerging clinical applications Contains contributions from leaders in cancer research, care, and clinical trials Offers an accessible guide to an accurate and balanced understanding of cancer and the cancer patient Focuses on the importance of cancer prevention, early detection, treatment, and survivorship Written for medical students, students of cancer biology, and caregivers and cancer patients, Cancer: Prevention, Early Detection, Treatment and Recovery offers an authoritative overview of the challenges and opportunities associated with cancer biology, cancer research, and the spectrum of clinical considerations.
Author : Visith Thongboonkerd
Publisher : John Wiley & Sons
ISBN 13 : 3527319743
Total Pages : 423 pages
Book Rating : 4.5/5 (273 download)
Download or read book Renal and Urinary Proteomics written by Visith Thongboonkerd and published by John Wiley & Sons. This book was released on 2009-12-21 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on research and results from the international Human Kidney and Urine Proteome Project, this handbook and reference presents current methods and protocols for the analysis of human kidney and urine. The world's leading experts cover everything from basic techniques for routine analysis to advanced methods for difficult samples or analytes. Written with the practitioner in mind, all the methods and techniques are described with step-by-step protocols backed by much valuable practical advice taken from real life experiments.
Author : Moulay Mustapha Ennaji
Publisher : Academic Press
ISBN 13 : 0323854974
Total Pages : 500 pages
Book Rating : 4.3/5 (238 download)
Download or read book Immunological Implications and Molecular Diagnostics of Genitourinary Cancer written by Moulay Mustapha Ennaji and published by Academic Press. This book was released on 2022-10-07 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunological Implications and Molecular Diagnostics of Genitourinary Cancer updates on recent accomplishments, unifying concepts, and future challenges in the study of tumor-associated immune cells, emphasizing genitourinary cancers. The presence of inflammatory immune cells in human tumors raise a fundamental question: How do cancer cells avoid destruction by immune attack? In principle, tumor development can be controlled by cytotoxic innate and adaptive immune cells, however, as tumors develop from neoplastic tissue to clinically detectable tumors, cancer cells evolve different mechanisms. This book covers research on the immunological implications of genitourinary cancer with a comprehensive view, especially surrounding diagnosis and cellular mechanisms. Discusses the impact of the immune system on the initiation, progression and treatment of cancer Provides insights on the important role of the suppressor genes and oncogenes in genitourinary cancers Shows the advantages of combining clinical issues of urologic cancers with immunological techniques, like immunohistochemistry and immunofluorescence Demonstrates the implications genitourinary cancer has on the human innate immune system
Author : Michel Bolla
Publisher : Springer
ISBN 13 : 3319427695
Total Pages : 422 pages
Book Rating : 4.3/5 (194 download)
Download or read book Management of Prostate Cancer written by Michel Bolla and published by Springer. This book was released on 2017-01-09 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, now in an extensively revised second edition, provides an exhaustive review of the state of the art in the management of prostate cancer, from screening to treatment, with emphasis on a multidisciplinary approach. The editors are very excited about the outstanding new or updated contributions from the different expert authors. The opening chapters address basic aspects including epidemiology, pathology, biology, genetics, and chemoprevention. The role of individual and mass screening is carefully appraised, and extensive attention is devoted to diagnosis and clinical work-up by means of recently implemented investigations such as multiparametric MRI and choline PET-CT. The use of active surveillance is examined in detail. Subsequent chapters discuss the different therapies that may be employed: open and minimally invasive, including robot-assisted, radical prostatectomy, the various forms of radiation treatment, high-intensity focused ultrasound, cryotherapy, hormonal manipulations, chemotherapy, targeted therapies, and immunotherapy. Up-to-date results from practice-changing phase III randomized clinical trials are included and special insights are provided into the interpretation of results and the patient’s perspective.
Author : Giampietro Gasparini
Publisher : Springer Science & Business Media
ISBN 13 : 159259915X
Total Pages : 335 pages
Book Rating : 4.5/5 (925 download)
Download or read book Biomarkers in Breast Cancer written by Giampietro Gasparini and published by Springer Science & Business Media. This book was released on 2008-01-17 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.
Author : Primo N. Lara
Publisher : Springer
ISBN 13 : 3319179039
Total Pages : 402 pages
Book Rating : 4.3/5 (191 download)
Download or read book Kidney Cancer written by Primo N. Lara and published by Springer. This book was released on 2015-06-10 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kidney Cancer: Principles and Practice is a comprehensive and interdisciplinary textbook that encompasses all clinically relevant aspects of the disease. This new edition has been extensively updated and includes brand new material covering the most recent developments in kidney cancer diagnosis and therapy. The user-friendly and clinically oriented content of the book guarantees that it will be of great interest to a wide range of medical professionals, and every effort has been made to ensure that contributions are both easy to understand and directly related to patient care. Content presentation departs from the usual dense chapter format featuring a lengthy series of paragraphs. Instead, each chapter contains several boxed sections, including one that summarizes essential "take home points" for the busy clinician and another that presents a patient-oriented case highlighting the clinical application of elements discussed in that chapter. In addition, accessible original images, illustrations, and diagrams (some in full color) are used to simplify particularly complex material. This book will be of value for clinicians, researchers, residents, fellows, students, and knowledgeable lay people. The contributors comprise an international group of authors with expertise in kidney cancer epidemiology, molecular biology, pathology, diagnosis, clinical features, staging, prognostic and predictive factors, surgery, systemic therapy, and emerging investigational approaches, among others.
Author : Rodolfo Montironi
Publisher : Frontiers Media SA
ISBN 13 : 2889459292
Total Pages : 79 pages
Book Rating : 4.8/5 (894 download)
Download or read book Emerging Biomarkers in Personalized Therapy of Urologic Tumors written by Rodolfo Montironi and published by Frontiers Media SA. This book was released on 2019-07-31 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: The identification of effective biomarkers has becoming a major focus in cancer research, mainly due to the necessity of selecting potentially responsive patients in order to improve their outcomes, as well as to reduce the toxicity and costs related to ineffective treatments. In genitourinary tumors, the lack of biomarkers does not allow for the development of personalized strategies for a single patient, thus representing a major goal in this field. This eBook includes the description of these emerging techniques and identify the most promising biomarkers in genitourinary tumors.
Author : Samanta Salvi
Publisher : Humana
ISBN 13 : 9781071613535
Total Pages : 214 pages
Book Rating : 4.6/5 (135 download)
Download or read book Urinary Biomarkers written by Samanta Salvi and published by Humana. This book was released on 2021-03-03 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes important methods, protocols, and techniques used for studying urinary biomarkers. Chapters detail different alterations use to studied different types of cancers and physiological conditions. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Urinary Biomarkers: Methods and Protocols aims to be a useful practical guide to researches to help further their study in this field.
Author : Seyed Mohammad Kazem Aghamir
Publisher : Academic Press
ISBN 13 : 0323983979
Total Pages : 210 pages
Book Rating : 4.3/5 (239 download)
Download or read book Liquid Biopsy in Urogenital Cancers and its Clinical Utility written by Seyed Mohammad Kazem Aghamir and published by Academic Press. This book was released on 2022-01-30 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liquid Biopsy in Urogenital Cancers and Their Clinical Utility presents updated information on liquid biopsy techniques and their utility for diagnosing urological cancers. As a promising and recent diagnostic method, these techniques can be used for identifying tumors at initial stage, thus greatly improving treatment outcomes and survivorship. Chapters provide an overview of liquid biopsy as a new tool for diagnosis, monitoring and personalized medicine in urogenital cancers and explain its applicability in different cancer types, including bladder, prostate, kidney and testis tumors, female genital tract and pediatric urogenital tumors. This is a valuable resource for cancer researchers, oncologists, graduate students, urologists and biomedical researchers who need to understand more about liquid biopsy and its use for urogenital cancers. Presents an overview on liquid biopsy techniques and their applications in cancer diagnosis Explains how to extract circulating tumor DNA, RNA and circulating tumor cells and extracellular vehicles from blood samples to identify the urology cancers, including testis, prostate, bladder and kidney Includes several images and schematic diagrams that illustrate content and facilitate its comprehension
Author : Axel S. Merseburger
Publisher : Springer
ISBN 13 : 9783319426228
Total Pages : 870 pages
Book Rating : 4.4/5 (262 download)
Download or read book Urologic Oncology written by Axel S. Merseburger and published by Springer. This book was released on 2019-08-21 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and timely textbook covers all aspects of the evidence-based management of genitourinary cancers and explains the fundamental principles underlying the available diagnostic and treatment approaches, including chemotherapy, radiotherapy, immunotherapy, and surgery. For each type of cancer – prostate, bladder, renal, testicular, and penile, plus rare urologic malignancies – clinical presentation, diagnosis, and treatment strategies are described in detail and information is provided on etiology, epidemiology, risk factors, and pathology, including TNM classification. Careful attention is also devoted to the complications that may be encountered when treating urologic malignancies and to the management of these complications. The text is complemented by the inclusion of numerous high-definition photographs and illustrations. Urologic Oncology will be a valuable reference and source of guidance for all oncologists, urologists and practitioners in related disciplines who treat patients with urologic cancers.
Author : Gabriel D. Dakubo
Publisher : Springer Nature
ISBN 13 : 3030247252
Total Pages : 296 pages
Book Rating : 4.0/5 (32 download)
Download or read book Cancer Biomarkers in Body Fluids written by Gabriel D. Dakubo and published by Springer Nature. This book was released on 2019-08-29 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to measure and monitor cancer biomarkers in “body fluid biopsy” should greatly impact oncologic practice. “Biomarkers in Proximal Fluids”, the third of the “Cancer Biomarkers in Body Fluids” series details cancer signatures in none or minimally circulating body fluids including saliva, sputum, bronchoalveolar lavage fluid, exhaled breath condensate, nipple aspirate fluid, gastric and pancreatic juice, stool, urine, and prostatic, peritoneal and cerebrospinal fluid. These fluids are enriched with biomarkers, especially those emanating from cells of the proximal tissue. Chapter 1 examines the global burden of cancer and the need for regional efforts at primary prevention, early detection and patient care. Chapters 2-12 address tissue-specific biomarkers in associated body fluids. The tumor interstitial fluid as a microenvironment rich in cancer biomarkers is detailed in chapter 13, while chapter 14 looks at the human body fluid microbiome and its evolving role in cancer. Commercially available assays using proximal fluids are examined at the end of the respective chapters. This book complements its predecessors and is equally useful to oncologists, cancer researchers, clinicians, medical students, nurses, diagnostic laboratory and pharmaceutical industry personnel.
