Biologie Et Genetique Moleculaires

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Aide-mémoire de biologie et génétique moléculaire - 3ème édition

Author : Bernard Swynghedauw
Publisher : Dunod
ISBN 13 : 2100537989
Total Pages : 178 pages
Book Rating : 4.1/5 (5 download)

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Book Synopsis Aide-mémoire de biologie et génétique moléculaire - 3ème édition by : Bernard Swynghedauw

Download or read book Aide-mémoire de biologie et génétique moléculaire - 3ème édition written by Bernard Swynghedauw and published by Dunod. This book was released on 2008-09-24 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cette 3e édition, en 2 couleurs est entièrement réécrite et re-illustrée. Elle comprend deux parties de même importance : biologie moléculaire et génétique. Le livre rend compte des dernières avancées : la parution de la séquence complète du génome humain; le développement de la génomique fonctionnelle, d'abord les techniques de protéomique, ensuite les techniques plus physiologiques; la diffusion des méthodes dites de «microarrays» qui permettent de pratiquer des analyses globales de l'expression génique de tissus; l'apparition d'une biologie intégrée dont l'outil essentiel est le transfert génique; l'évolution de la génétique moléculaire vers la génétique des populations ou la génétique évolutionniste.

Génétique moléculaire humaine

Author : Tom Strachan
Publisher : Companyédition Médecine Sciences Publications/Lavoisier
ISBN 13 : 9782257204196
Total Pages : 781 pages
Book Rating : 4.2/5 (41 download)

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Book Synopsis Génétique moléculaire humaine by : Tom Strachan

Download or read book Génétique moléculaire humaine written by Tom Strachan and published by Companyédition Médecine Sciences Publications/Lavoisier. This book was released on 2012 with total page 781 pages. Available in PDF, EPUB and Kindle. Book excerpt: Depuis la publication, en 2004, de la séquence complète du génome humain grâce au Projet Génome Humain, de grandes banques de séquences d'ADN sont produites chaque année. De puissants programmes bioinformatiques sont capables de comparer les génomes d'organismes différents. La génétique comparative permet ainsi de comprendre l'évolution du génome humain et celui de nombreux autres organismes modèles, ouvrant la voie à la recherche biomédicale. De grands projets internationaux ont été mis en place afin de comprendre le fonctionnement de nos gènes : le projet ENCODE vise à créer une encyclopédie des éléments fonctionnels de notre ADN ; le projet HapMap étudie les variations génétiques dans la population mondiale, permettant aux chercheurs d'identifier les gènes impliqués dans les maladies. Enfin le développement constant de nouvelles technologies telles que le génotypage à haut débit des SNP ou les micropuces à ADN offre des outils puissants et hautement performants. La 4e édition de Génétique moléculaire humaine intègre ces avancées scientifiques et technologiques. Véritable pont entre les manuels de base et la littérature issue de la recherche, l'ouvrage fournit en 21 chapitres le cadre permettant de comprendre ce domaine, depuis les aspects fondamentaux jusqu'aux notions les plus pointues de biologie moléculaire. Après des chapitres généraux sur la structure et la fonction des acides nucléiques, des chromosomes, la répartition des gènes dans la population, il présente les techniques d'étude et d'analyse des gènes. Des chapitres très développés et à la pointe des connaissances actuelles portent sur l'épigénétique, les ARN non codants, les cellules souches. Les principaux organismes modèles utilisés dans les études génétiques et l'étude des maladies humaines sont décrits en détail. Les traitements des maladies humaines - et les questions d'éthique qui en découlent - sont abordés à travers les tests et analyses génétiques, l'utilisation des cellules souches, la thérapie cellulaire, génique, oligonucléotidique et la médecine personnalisée. Enfin, un glossaire de plus de 600 définitions et un index de près de 10 000 entrées complètent ce livre exhaustif, actuel et richement illustré. L'ouvrage intéresse les étudiants en médecine, en biologie, en sciences et leurs enseignants ; les généticiens, les biologistes, les pédiatres ainsi que les personnes désireuses d'appréhender de manière scientifique la génétique moléculaire humaine et ses applications médicales.

Biologie moléculaire du gène

Author : James Dewey Watson
Publisher :
ISBN 13 : 9782744076596
Total Pages : 688 pages
Book Rating : 4.0/5 (765 download)

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Book Synopsis Biologie moléculaire du gène by : James Dewey Watson

Download or read book Biologie moléculaire du gène written by James Dewey Watson and published by . This book was released on 2012-11-02 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Du gène de l'immortalité (des cellules souches embryonnaires) aux gènes dont les mutations sont responsables de pathologies diverses en passant par l'appétit, le langage, etc., la liste de nouveaux gènes mis en évidence, ces dernières années, n’en finit pas. Le lien entre les gènes et les caractères qu’ils gouvernent constitue le coeur de la biologie moléculaire. Les applications et les retombées sociétales de ces connaissances rendent de plus en plus nécessaire la compréhension de cette discipline. Écrit, dans un style clair et accessible, par de grands spécialistes mondiaux de biologie moléculaire dont le Prix Nobel, découvreur de la double hélice de l’ADN, JD Watson, ce livre en intègre les principaux aspects : les propriétés physicochimiques et les bases structurales des acides nucléiques et des protéines ; les mécanismes de la maintenance et de l’expression du génome ; les mécanismes de régulation ; les méthodes. Par ailleurs des approfondissements (théoriques ou expérimentaux) et des applications en clinique humaine sont proposés sur des domaines à la pointe du progrès. Enfin cet ouvrage se distingue aussi par la large place donnée à l’histoire de cette discipline. La compréhension et l’intégration des connaissances sont facilitées grâce à : Des schémas clairs et légendés, avec une abondante iconographie. Des encadrés « Pour aller plus loin », « Applications en clinique humaine », « Expériences clés », « Techniques » qui aiguisent l’intérêt du lecteur. Un glossaire-dictionnaire français-anglais comprenant plus de 700 définitions. Cet ouvrage, qui a bénéficié d’une traduction-actualisation de qualité grâce à des traducteurs pédagogues, hautement qualifiés et spécialisés, constitue un manuel de cours d’initiation parfaitement adapté pour accompagner l’étudiant dès les premières années de son cursus. Il comblera également les attentes de tous les étudiants de 3e cycle et des chercheurs à la recherche d’un ouvrage de synthèse récent qui comprend les dernières avancées scientifiques : par exemple, dans les nouveaux chapitres sur les ARN régulateurs, sur l’analyse du génome et la biologie des systèmes. Il constituera aussi un support actualisé pour les enseignants.

Principes des techniques de biologie moléculaire

Author : Denis Tagu
Publisher : Editions Quae
ISBN 13 : 9782738010674
Total Pages : 186 pages
Book Rating : 4.0/5 (16 download)

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Book Synopsis Principes des techniques de biologie moléculaire by : Denis Tagu

Download or read book Principes des techniques de biologie moléculaire written by Denis Tagu and published by Editions Quae. This book was released on 2006 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: La biologie moléculaire a bouleversé les sciences du vivant L'explosion de la génomique, qui propose des séquences de génomes entiers ainsi que des approches globales de leur fonctionnement, en est un exemple récent. L'objectif de cet ouvrage présenté sous forme de fiches n'est pas de détailler des protocoles ou des recettes toutes faites, mais d'expliquer simplement les principes théoriques des techniques de biologie moléculaire. Cette édition mise à jour propose des illustrations nouvelles et présente notamment de nombreuses techniques de génomique récemment apparues dans les laboratoires. Cet ouvrage s'adresse à toute personne - spécialiste ou non - curieuse de connaître les bases des différentes techniques de manipulation des acides nucléiques.

Génétique et Biologie Moléculaire

Author : Guillaume Grzych
Publisher : De Boeck Supérieur
ISBN 13 : 2807335594
Total Pages : 112 pages
Book Rating : 4.8/5 (73 download)

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Book Synopsis Génétique et Biologie Moléculaire by : Guillaume Grzych

Download or read book Génétique et Biologie Moléculaire written by Guillaume Grzych and published by De Boeck Supérieur. This book was released on 2021-08-23 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cet ouvrage mis à jour aborde les notions de génétique en lien avec les items 1 à 6 de la section II et les items 54 et 55 de la section IV du programme de l'internat en pharmacie. Il propose un résumé de l’essentiel à connaître en génétique, des bases physiologiques jusqu’aux techniques permettant d’identifier et de caractériser les anomalies génétiques. Il est composé de 3 parties principales : • Rappel des bases en génétique • Exploration et caractérisation des anomalies génétiques • Entraînement sous forme de QCM et exercices. Ces fiches mises à jour ont été conçues de façon claire et aérée afin de retenir l’essentiel nécessaire à la compréhension et à la résolution des problématiques concernant la génétique au cours des études de pharmacie.

Génétique, génétique moléculaire, évolution moléculaire

Author : Jean Bouvet
Publisher :
ISBN 13 : 9782907193542
Total Pages : 255 pages
Book Rating : 4.1/5 (935 download)

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Book Synopsis Génétique, génétique moléculaire, évolution moléculaire by : Jean Bouvet

Download or read book Génétique, génétique moléculaire, évolution moléculaire written by Jean Bouvet and published by . This book was released on 1992 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt:

From Gene to Animal

Author : David de Pomerai
Publisher : CUP Archive
ISBN 13 : 9780521388566
Total Pages : 438 pages
Book Rating : 4.3/5 (885 download)

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Book Synopsis From Gene to Animal by : David de Pomerai

Download or read book From Gene to Animal written by David de Pomerai and published by CUP Archive. This book was released on 1990-12-13 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: An exposition of current understanding of the way that hierarchies of genes control aspects of animal development. Emphasis is placed on the best studied systems, nameley "Drosophila" and the nematode "Caenorhabditis".

Molecular Biology and Genomics

Author : Cornel Mulhardt
Publisher : Elsevier
ISBN 13 : 0080467660
Total Pages : 273 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Molecular Biology and Genomics by : Cornel Mulhardt

Download or read book Molecular Biology and Genomics written by Cornel Mulhardt and published by Elsevier. This book was released on 2010-07-19 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Never before has it been so critical for lab workers to possess the proper tools and methodologies necessary to determine the structure, function, and expression of the corresponding proteins encoded in the genome. Mulhardt's Molecular Biology and Genomics helps aid in this daunting task by providing the reader with tips and tricks for more successful lab experiments. This strategic lab guide explores the current methodological variety of molecular biology and genomics in a simple manner, addressing the assets and drawbacks as well as critical points. It also provides short and precise summaries of routine procedures as well as listings of the advantages and disadvantages of alternative methods. Shows how to avoid experimental dead ends and develops an instinct for the right experiment at the right time Includes a handy Career Guide for researchers in the field Contains more than 100 extensive figures and tables

From DNA to Diversity

Author : Sean B. Carroll
Publisher : John Wiley & Sons
ISBN 13 : 1118685202
Total Pages : 475 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis From DNA to Diversity by : Sean B. Carroll

Download or read book From DNA to Diversity written by Sean B. Carroll and published by John Wiley & Sons. This book was released on 2013-04-25 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this landmark work, the author team led by Dr. Sean Carroll presents the general principles of the genetic basis of morphological change through a synthesis of evolutionary biology with genetics and embryology. In this extensively revised second edition, the authors delve into the latest discoveries, incorporating new coverage of comparative genomics, molecular evolution of regulatory proteins and elements, and microevolution of animal development. An accessible text, focusing on the most well-known genes, developmental processes and taxa. Builds logically from developmental genetics and regulatory mechanisms to evolution at different genetic morphological levels. Adds major insights from recent genome studies, new evo-devo biology research findings, and a new chapter on models of variation and divergence among closely related species. Provides in-depth focus on key concepts through well-developed case studies. Features clear, 4-color illustrations and photographs, chapter summaries, references and a glossary. Presents the research of Dr. Carroll, a pioneer in the field and the past president of the Society for Developmental Biology.

Molecular Mechanisms in the Control of Gene Expression

Author : Donald P. Nierlich
Publisher : Elsevier
ISBN 13 : 1483273938
Total Pages : 668 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Molecular Mechanisms in the Control of Gene Expression by : Donald P. Nierlich

Download or read book Molecular Mechanisms in the Control of Gene Expression written by Donald P. Nierlich and published by Elsevier. This book was released on 2013-10-22 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Mechanisms in the Control of Gene Expression documents the proceedings of the ICN-UCLA conference on Molecular Mechanisms in the Control of Gene Expression, organized through the Molecular Biology Institute of UCLA, held in Keystone, Colorado, 21-26 March 1976. The conference focused on three topics: the action of repressors on specific nucleotide sequences in DNA; how DNA and histones are intertwined in eucaryotic chromosomes; and in the development of new techniques that appear to lift genes from complex genomes. The volume contains 65 chapters organized into nine parts. The papers in Part I examine the organization of prokaryotic and eukaryotic chromosomes. Part II presents studies on the interaction of RNA a polymerase and regulatory molecules with defined DNA sites. Parts III and IV focus on RNA polymerases of eukaryotes and the regulation of transcription in eukaryotic systems, respectively. Part V contains papers dealing with nucleic acid sequences, transcription, and processing. Part VI covers cellular aspects in the study of gene expression. Part VII takes up cloning while Part VIII is devoted to genetic analysis through restriction mapping and molecular cloning. Finally, Part IX summarizes the recent progress reported at the conference and also indicates some of the limitations that can be placed upon interpretation of data.

Darwin in the Genome

Author : Lynn Helena Caporale
Publisher : Darwin in the Genome
ISBN 13 : 0071378227
Total Pages : 259 pages
Book Rating : 4.0/5 (713 download)

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Book Synopsis Darwin in the Genome by : Lynn Helena Caporale

Download or read book Darwin in the Genome written by Lynn Helena Caporale and published by Darwin in the Genome. This book was released on 2003 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher Description

Molecular Biology of the Gene

Author : James D. Watson
Publisher :
ISBN 13 :
Total Pages : 524 pages
Book Rating : 4.:/5 (41 download)

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Book Synopsis Molecular Biology of the Gene by : James D. Watson

Download or read book Molecular Biology of the Gene written by James D. Watson and published by . This book was released on 1965 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mendelian view of the world; Cells obey the laws of chemistry; A chemist's look at the bacterial cell; The importance of weak chemical interactions; Coupled reactions and group transfers; The concept of template surfaces; The arrangement of genes on chromosomes; Gene sttructure and function.

Human Molecular Genetics

Author : Tom Strachan
Publisher : Garland Science
ISBN 13 : 1136844074
Total Pages : 808 pages
Book Rating : 4.1/5 (368 download)

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Book Synopsis Human Molecular Genetics by : Tom Strachan

Download or read book Human Molecular Genetics written by Tom Strachan and published by Garland Science. This book was released on 2018-03-29 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Molecular Genetics is an established and class-proven textbook for upper-level undergraduates and graduate students which provides an authoritative and integrated approach to the molecular aspects of human genetics. While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject. The text has been restructured so genomic technologies are integrated throughout, and next generation sequencing is included. Genetic testing, screening, approaches to therapy, personalized medicine, and disease models have been brought together in one section. Coverage of cell biology including stem cells and cell therapy, studying gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics have all been expanded.

Human Molecular Genetics

Author :
Publisher : Academic Press
ISBN 13 : 0080536417
Total Pages : 521 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Human Molecular Genetics by :

Download or read book Human Molecular Genetics written by and published by Academic Press. This book was released on 1996-05-23 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Molecular Genetics is a practical guide to the applications of molecular biology and genetics techniques to human cells. A wide range of experimental procedures for investigating human genes and genomes are presented. * * Mutation Detection in Human Genes - chemical mismatch cleavage, DNA mini-sequencing, SSCP method, RT-PCR, electrophoretic mobility shift assay (EMSA), protein truncation test, chromosome deletion analysis.* Gene Mapping, Cloning, Sequencing - gene linkage determination, large-capacity cloning system, cDNA isolation, differential display method, primer-based DNA sequencing.* Transcription: Promoters, Transcription Factors, mRNA, - promotor mutation analysis, transcription factor identification, mRNA-protein interaction characterization.* RNA Editing, Ribozymes, Antisense RNA-mammalian RNA editing assays, ribozymes as genetic tools, antisense RNA technology.* Genome Recombination, Amplification - recombination assays for mammalian cells, gene amplification measurement.* Receptors, Signal Transduction - intra-cellular receptor characterization, analysis of signal transduction genes.* The Mouse as a Model System for Human Molecular Genetics - mouse genome methods (mouse crosses, somatic cell hybrids, YACs), mouse model for cardiovascular disease.

From Genes to Genomes

Author : Jeremy W. Dale
Publisher : John Wiley & Sons
ISBN 13 : 0470518707
Total Pages : 394 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis From Genes to Genomes by : Jeremy W. Dale

Download or read book From Genes to Genomes written by Jeremy W. Dale and published by John Wiley & Sons. This book was released on 2008-03-11 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: “... an excellent book... achieves all of its goals with style, clarity and completeness... You can see the power and possibilities of molecular genetics as you read...” –Human Genetics "This volume hits an outstanding balance among readability, coverage, and detail." –Biochemistry and Molecular Biology Education Rapid advances in a collection of techniques referred to as gene technology, genetic engineering, recombinant DNA technology and gene cloning have pushed molecular biology to the forefront of the biological sciences. This new edition of a concise, well-written textbook introduces key techniques and concepts involved in cloning genes and in studying their expression and variation. The book opens with a brief review of the basic concepts of molecular biology, before moving on to describe the key molecular methods and how they fit together. This ranges from the cloning and study of individual genes to the sequencing of whole genomes, and the analysis of genome-wide information. Finally, the book moves on to consider some of the applications of these techniques, in biotechnology, medicine and agriculture, as well as in research that is causing the current explosion of knowledge across the biological sciences. From Genes to Genomes: Concepts and Applications of DNA Technology, Second Edition includes full two-colour design throughout. Specific changes for the new edition include: Strengthening of gene to genome theme Updating and reinforcing of material on proteomics, gene therapy and stem cells More eukaryotic/mammalian examples and less focus on bacteria This textbook is must-have for all undergraduates studying intermediate molecular genetics within the biological and biomedical sciences. It is also of interest for researchers and all those needing to update their knowledge of this rapidly moving field.

Genetics

Author : Terence A. Brown
Publisher : International Thomson Publishing Services
ISBN 13 :
Total Pages : 512 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Genetics by : Terence A. Brown

Download or read book Genetics written by Terence A. Brown and published by International Thomson Publishing Services. This book was released on 1998 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This introductory text covers all aspects of genetics but adopts a "molecular approach", with the gene dealt with first as a chemical structure and then as a Menedelian entity.

The Misunderstood Gene

Author : Michel Morange
Publisher :
ISBN 13 :
Total Pages : 250 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Misunderstood Gene by : Michel Morange

Download or read book The Misunderstood Gene written by Michel Morange and published by . This book was released on 2001 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: At a time when the complete human genome has been sequenced and when seemingly every week feature news stories describe genes that may be responsible for personality, intelligence, even happiness, Michel Morange gives us a book that demystifies the power of modern genetics. The Misunderstood Gene takes us on an easily comprehensible tour of the most recent findings in molecular biology to show us how--and if--genes contribute to biological processes and complex human behaviors. As Morange explains, if molecular biologists had to designate one category of molecules as essential to life, it would be proteins and their multiple functions, not DNA and genes. Genes are the centerpiece of modern biology because they can be modified. But they are only the memory that life invented so that proteins could be efficiently reproduced. Morange shows us that there is far more richness and meaning in the structure and interactions of proteins than in all the theoretical speculations on the role of genes. The Misunderstood Gene makes it clear that we do not have to choose between rigid genetic determinism and fearful rejection of any specific role for genes in development or behavior. Both are true, but at different levels of organization. Morange agrees with those who say "we are not in our genes." But he also wants us to understand that we are not without our genes, either. We are going to have to make do with them, and this book will show us how.