Biologics For The Treatment Of Rheumatoid Arthritis

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Biologics for the Treatment of Rheumatoid Arthritis

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Author : Ronald van Vollenhoven
Publisher : Springer
ISBN 13 : 3319131087
Total Pages : 139 pages
Book Rating : 4.3/5 (191 download)

Book Synopsis Biologics for the Treatment of Rheumatoid Arthritis by : Ronald van Vollenhoven

Download or read book Biologics for the Treatment of Rheumatoid Arthritis written by Ronald van Vollenhoven and published by Springer. This book was released on 2015-12-22 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the available biologic therapies whilst comparing them to standard disease modifying anti-rheumatic drugs, and discusses how best to determine which therapy is most appropriate for an individual patient in the framework of current guidelines. Biologics for the Treatment of Rheumatoid Arthritis is an up-to-date and concise practical guide to the latest therapeutic developments in this field. This book is an invaluable source of topical information for all rheumatologists and health care professionals treating patients with rheumatoid arthritis.

Early Rheumatoid Arthritis

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Author : Paul Emery
Publisher :
ISBN 13 : 9781416027676
Total Pages : 0 pages
Book Rating : 4.0/5 (276 download)

Book Synopsis Early Rheumatoid Arthritis by : Paul Emery

Download or read book Early Rheumatoid Arthritis written by Paul Emery and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue covers the latest developments in the understanding of rheumatoid arthritis at the early stage. Treatments such as with newer biologic agents and conventional disease-modifying antirheumatic drugs are reviewed. Also included are articles on imaging modalities as a means of identifying those in the early stages and monitoring response to treatment.

Biologics in General Medicine

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Author : W.-H. Boehncke
Publisher : Springer Science & Business Media
ISBN 13 : 3540290176
Total Pages : 202 pages
Book Rating : 4.5/5 (42 download)

Book Synopsis Biologics in General Medicine by : W.-H. Boehncke

Download or read book Biologics in General Medicine written by W.-H. Boehncke and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to cover every angle in the clinical application of biologics. Readers will not only find that all of the biologics currently approved for clinical use are delineated in a standardized way, but also the "differential therapy" with biologics in fields including dermatology and neurology is described in detail and summarized in treatment algorithms. Shorter sections on biologic biotechnology as well as safety and regulatory issues complement the more clinically-oriented central chapters.

Biologics in Rheumatology

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Author : Coziana Ciurtin
Publisher :
ISBN 13 : 9781634853026
Total Pages : 539 pages
Book Rating : 4.8/5 (53 download)

Book Synopsis Biologics in Rheumatology by : Coziana Ciurtin

Download or read book Biologics in Rheumatology written by Coziana Ciurtin and published by . This book was released on 2016 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant progress has been acquired in the treatment of rheumatic conditions with the introduction of biologic therapies, which has enabled better control of disease activity and improved patients' long-term outcome. Apart from several biologic treatments already licensed for use in autoimmune rheumatic conditions, numerous other agents are currently under investigation. This rapid expansion of the therapeutic armamentarium requires a critical analysis of individual biologic options and their clinical indications, in order to facilitate the optimal use of these new therapies. The authors felt that a comprehensive book revisiting all the evidence available regarding the efficacy, cost-effectiveness and health implications of the use of biologics in rheumatology was needed in order to integrate the clinical, ethical and socio-economic aspects related to their use. This book is aimed at specialist doctors, trainees, nurses and health professionals working in the field of rheumatology. It critically appraises the level of evidence behind the use of biologic agents in diverse autoimmune diseases, comprising separate chapters which focus on rheumatoid arthritis, systemic lupus erythematosus, myositis, systemic sclerosis, Sjogren's syndrome, seronegative spondyloarthropathies, psoriatic arthritis and psoriasis, small, medium and large vessel vasculitis, osteoporosis, and interstitial lung disease associated with rheumatic conditions. In addition, the book explores aspects related to the use of biologic agents, such as ethical considerations of consenting patients to take part in clinical trials with biologics, and adolescent and adult rheumatology nurse perspectives related to patients' benefits of biologic therapies. Particular interest is given to the use of biologics during pregnancy and assessment of their infectious risks. A separate chapter explores the off-target benefits associated with the use of anti-TNF therapies. Several chapters include data about cost-effectiveness, and national and international guidelines for the use of biologic agents in different rheumatic conditions.

Handbook of Biologics for Rheumatological Disorders

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Author : Neeraj Jain
Publisher : Springer Nature
ISBN 13 : 9811672008
Total Pages : 286 pages
Book Rating : 4.8/5 (116 download)

Book Synopsis Handbook of Biologics for Rheumatological Disorders by : Neeraj Jain

Download or read book Handbook of Biologics for Rheumatological Disorders written by Neeraj Jain and published by Springer Nature. This book was released on 2022-03-06 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biologics have revolutionized the treatment of autoimmune diseases due to their efficacy, speed of onset, and tolerability. The development of new agents and expanded use of existing agents continues to be a highly active area of investigation among rheumatic diseases, with a multitude of innovative therapeutic strategies in various stages of development. Although the story of treatments continues rapidly, therapeutic research in some conditions is hindered by the rarity of the disease, variation in phenotype, and concerns about toxicity. This fast-paced development of therapeutics,necessitates immediate evaluation of individual biologic agents and their best use in the new treatment regimens./div This book provides an inclusive approach with the existing evidence concerning effectiveness and implications on the usage of biologics in treating various rheumatologic disorders. It also covers the evidence behind the rational use of these agents in varied autoimmune diseases. This manual also offers a complete overview of the existing & futuristic biologic treatments, and draws recommendations on how to standardize the most suitable regimen for a specific patient in the context of current guidelines. The handbook of Biologics in Rheumatology serves as a present and concise compendium to the modern therapeutic developments in the field./div This book is likely to benefit clinicians, residents, fellow and other healthcare workers dealing with rheumatological disorders, and also hard-core Rheumatologists, who are looking for a quick recap of Biologics of their interest. /div

Safe and Effective Medicines for Children

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Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309225493
Total Pages : 432 pages
Book Rating : 4.3/5 (92 download)

Book Synopsis Safe and Effective Medicines for Children by : Institute of Medicine

Download or read book Safe and Effective Medicines for Children written by Institute of Medicine and published by National Academies Press. This book was released on 2012-10-13 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Best Pharmaceuticals for Children Act (BPCA) and the Pediatric Research Equity Act (PREA) were designed to encourage more pediatric studies of drugs used for children. The FDA asked the IOM to review aspects of pediatric studies and changes in product labeling that resulted from BPCA and PREA and their predecessor policies, as well as assess the incentives for pediatric studies of biologics and the extent to which biologics have been studied in children. The IOM committee concludes that these policies have helped provide clinicians who care for children with better information about the efficacy, safety, and appropriate prescribing of drugs. The IOM suggests that more can be done to increase knowledge about drugs used by children and thereby improve the clinical care, health, and well-being of the nation's children.

Introduction to Basics of Pharmacology and Toxicology

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Author : Abialbon Paul
Publisher : Springer Nature
ISBN 13 : 9813360097
Total Pages : 1156 pages
Book Rating : 4.8/5 (133 download)

Book Synopsis Introduction to Basics of Pharmacology and Toxicology by : Abialbon Paul

Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

Biologic Treatment for Rheumatoid Arthritis

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Author : Bassem Akiki
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (14 download)

Book Synopsis Biologic Treatment for Rheumatoid Arthritis by : Bassem Akiki

Download or read book Biologic Treatment for Rheumatoid Arthritis written by Bassem Akiki and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present study was done in order to prove the efficacy of biologic treatment for rheumatoid arthritis patients while being careful for the rare but serious side effects of the biologic drugs. We studied, retrospectively, a sample of 31 patients, diagnosed with RA and treated with different biologic drugs (anti TNFa: etanercept, adalimumab, infliximab; anti CD20: rituximab; anti IL6: tocilizumab ). We assessed efficacy according to the evolution of ESR and DAS28 6 months after initiating the biologic drug. All patients were monitored and screened for any side effect or adverse event during their treatment. The results showed a significant reduction in both ESR and DAS28. And the emergence of some adverse events: infections (pneumonia: 13%, primary herpes: 3.22%, herpes zoster: 3.22%), demyelination disorder (3.22%), allergic reactions (rash/pruritis: 13%), GI disorders (diarrhea: 6.45%, nausea: 3.22%) hematologic disorders (anemia: 6.45%, leucopenia: 3.22%), asthenia (16.12%), menometrorrhagia (3.22%). However none of our patients was diagnosed with a malignancy. In conclusion, despite the risk of adverse events, biologics remain an important and essential therapeutic option for RA patients due to their proven efficacy.

Dubois' Lupus Erythematosus

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Author : Daniel Jeffrey Wallace
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781793940
Total Pages : 1516 pages
Book Rating : 4.7/5 (939 download)

Book Synopsis Dubois' Lupus Erythematosus by : Daniel Jeffrey Wallace

Download or read book Dubois' Lupus Erythematosus written by Daniel Jeffrey Wallace and published by Lippincott Williams & Wilkins. This book was released on 2007 with total page 1516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Established for forty years as the definitive reference on lupus, Dubois' Lupus Erythematosus is now in its thoroughly revised, updated Seventh Edition. More than ninety distinguished contributing authors—twenty of them new to this edition—provide comprehensive coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. This edition focuses on evidence-based findings, treatment consensuses, and practical clinical information. New chapters cover cytokines and interferons, pathogenesis of atherosclerosis, immune tolerance, clinical indices in assessment of lupus, mixed connective tissue disease, reproductive issues, fibromyalgia, gender-related issues, and biomarkers.

The Development of Local-acting Biologics to Treat Rheumatoid Arthritis

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Author : Eric John Neely
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (133 download)

Book Synopsis The Development of Local-acting Biologics to Treat Rheumatoid Arthritis by : Eric John Neely

Download or read book The Development of Local-acting Biologics to Treat Rheumatoid Arthritis written by Eric John Neely and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and progressive joint destruction. Anti-TNF biologics have been developed to treat RA and although effective in the majority of patients, they require repeated administration and systemically inhibit TNF. This systemic inhibition leads to systemic immune suppression and can result in side-effects including opportunistic infections, serious infections and malignancy. To address these limitations, I developed a novel, local-acting biologic known as TNF sticky trap. This biologic was shown capable of inhibiting TNF while sticking or localizing to the extracellular matrix (ECM) where it is produced or administered. Next, cell lines inducibly expressing this local-acting biologic were generated, characterized and evaluated for their therapeutic efficacy in an animal model of RA. A single injection of cells expressing TNF sticky trap was sufficient to reduce arthritis and this local-acting biologic was undetectable in the serum of treated animals. Lastly, to help advance the translation of RA cell therapies into the clinic, a cell safety mechanism was developed and characterized. The development of a safe cell therapy inducibly expressing local-acting biologics could avoid the limitations associated with systemic therapies and improve the current treatment of RA.

Biologics for Early Rheumatoid Arthritis

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Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (14 download)

Book Synopsis Biologics for Early Rheumatoid Arthritis by :

Download or read book Biologics for Early Rheumatoid Arthritis written by and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Oxford Textbook of Rheumatoid Arthritis

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Author : David L. Scott
Publisher : Oxford University Press, USA
ISBN 13 : 0198831439
Total Pages : 577 pages
Book Rating : 4.1/5 (988 download)

Book Synopsis Oxford Textbook of Rheumatoid Arthritis by : David L. Scott

Download or read book Oxford Textbook of Rheumatoid Arthritis written by David L. Scott and published by Oxford University Press, USA. This book was released on 2020-05-12 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Oxford Textbook of Rheumatoid Arthritis covers all relevant aspects of the fisease, ranging from basic science, epidemiology, clinical and laboratory assessments, drug and non-drug treatments, and disease outcomes. Written by an international team of experts, it will be an invaluable resource for those involved with people with RA.

Rheumatoid Arthritis

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Author : John J. Cush
Publisher :
ISBN 13 : 1932610286
Total Pages : 368 pages
Book Rating : 4.9/5 (326 download)

Book Synopsis Rheumatoid Arthritis by : John J. Cush

Download or read book Rheumatoid Arthritis written by John J. Cush and published by . This book was released on 2008-01-01 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizes the importance of early intervention in RA with focus on pharmacologic treatment of RA. Detailed information on the various medications employed in treatment, including corticosteroids, NSAIDs DMARDs, biologic agents, and combination therapy is reviewed, including evidence based data on efficacy, safety, side effects, and monitoring requirements. Clinical evaluation is presented, including lab findings, joint scoring, diagnostic criteria, and radiographic outcomes. Surgical options and the management of advanced RA are disussed.

Biologics, Biosimilars, and Biobetters

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Author : Iqbal Ramzan
Publisher : John Wiley & Sons
ISBN 13 : 1119564654
Total Pages : 328 pages
Book Rating : 4.1/5 (195 download)

Book Synopsis Biologics, Biosimilars, and Biobetters by : Iqbal Ramzan

Download or read book Biologics, Biosimilars, and Biobetters written by Iqbal Ramzan and published by John Wiley & Sons. This book was released on 2021-02-03 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive primer and reference, this book provides pharmacists and health practitioners the relevant science and policy concepts behind biologics, biosimilars, and biobetters from a practical and clinical perspective. Explains what pharmacists need to discuss the equivalence, efficacy, safety, and risks of biosimilars with physicians, health practitioners, and patients about Guides regulators on pragmatic approaches to dealing with these drugs in the context of rapidly evolving scientific and clinical evidence Balances scientific information on complex drugs with practical information, such as a checklist for pharmacists

Encyclopedia of Medical Immunology

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Author : Ian R. Mackay
Publisher :
ISBN 13 : 9781461492092
Total Pages : pages
Book Rating : 4.4/5 (92 download)

Book Synopsis Encyclopedia of Medical Immunology by : Ian R. Mackay

Download or read book Encyclopedia of Medical Immunology written by Ian R. Mackay and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering a broad appeal to microbiologists, immunologists, and infectious disease specialists, this four volume encyclopedia covers all autoimmune, tropical, and infectious diseases. Emphasis will also be placed on genetics, physiology, metabolism, pathogenesis and applied microbiology. Under the leadership of some of the most world renowned names in the field, the encyclopedia will bring together an outstanding collection of contributions by top scientists in a variety of fields. Volumes 1-3: Diseases will be divided by the 11 main sections of the body, namely Integumentary, Skeletal, Respiratory, Digestive, Urinary, and Reproductive. For some of the autoimmune disease, more then one system will be involved but the delineation serves to broadly break down the diseases into systems. Volume 4 will cover the vaccines for said diseases and future prospects will be offered by leaders in industry and academia. Volume 4 will also be broken down into all the body systems, as in the other two volumes. For each vaccine, for each disease, and in each system the following will be included: • A list of the vaccines currently available along with a list of the companies that manufacture them • Molecular Immunology of the Vaccine • Type of Immunity involved in protection • Mode of Vaccination for each vaccine; repeated boosters and length of immunological memory • Commercial production of vaccines • Storage of vaccines • Standardization and Control of Vaccines • WHO programs and World-Wide Disease Eradication Programs based upon Vaccines.

Pharmacoepidemiology

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Author : Brian L. Strom
Publisher : John Wiley & Sons
ISBN 13 : 1119413419
Total Pages : 1220 pages
Book Rating : 4.1/5 (194 download)

Book Synopsis Pharmacoepidemiology by : Brian L. Strom

Download or read book Pharmacoepidemiology written by Brian L. Strom and published by John Wiley & Sons. This book was released on 2019-12-16 with total page 1220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This classic, field-defining textbook, now in its sixth edition, provides the most comprehensive guidance available for anyone needing up-to-date information in pharmacoepidemiology. This edition has been fully revised and updated throughout and continues to provide a rounded view on all perspectives from academia, industry and regulatory bodies, addressing data sources, applications and methodologies with great clarity.

Autoimmune and Inflammatory Rheumatic Diseases: Identifying Biomarkers of Response to Therapy with Biologics

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Author : Anna Lisa Giuliani
Publisher : Frontiers Media SA
ISBN 13 : 2889742245
Total Pages : 142 pages
Book Rating : 4.8/5 (897 download)

Book Synopsis Autoimmune and Inflammatory Rheumatic Diseases: Identifying Biomarkers of Response to Therapy with Biologics by : Anna Lisa Giuliani

Download or read book Autoimmune and Inflammatory Rheumatic Diseases: Identifying Biomarkers of Response to Therapy with Biologics written by Anna Lisa Giuliani and published by Frontiers Media SA. This book was released on 2022-03-14 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: