Administered Radiopharmaceutical Activity and Radiation Dosimetry in Paediatric Nuclear Medicine

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Publisher :
ISBN 13 :
Total Pages : 158 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Administered Radiopharmaceutical Activity and Radiation Dosimetry in Paediatric Nuclear Medicine by : Eleonor Vestergren

Download or read book Administered Radiopharmaceutical Activity and Radiation Dosimetry in Paediatric Nuclear Medicine written by Eleonor Vestergren and published by . This book was released on 1998 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Energy Research Abstracts

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Publisher :
ISBN 13 :
Total Pages : 334 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Energy Research Abstracts by :

Download or read book Energy Research Abstracts written by and published by . This book was released on 1992-11 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nuclear Medicine Resources Manual

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Publisher : International Atomic Energy Agency
ISBN 13 : 9789201040190
Total Pages : pages
Book Rating : 4.0/5 (41 download)

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Book Synopsis Nuclear Medicine Resources Manual by : International Atomic Energy Agency

Download or read book Nuclear Medicine Resources Manual written by International Atomic Energy Agency and published by International Atomic Energy Agency. This book was released on 2021-03-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical imaging is crucial in a variety of medical settings and at all levels of health care. In public health and preventive medicine as well as in both curative and palliative care, effective decisions depend on correct diagnoses. This edition addresses the most current needs and offers guidance on clinical practice, radiation safety and patient protection, human resource development and training required for the overall practice of nuclear medicine.

Clinical Nuclear Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 354028026X
Total Pages : 573 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Clinical Nuclear Medicine by : Hans-Jürgen Biersack

Download or read book Clinical Nuclear Medicine written by Hans-Jürgen Biersack and published by Springer Science & Business Media. This book was released on 2008-01-03 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has true international scope, being a unique European/American joint venture that focuses on the state of the art in both diagnostic and therapeutic radionuclide methodology. Pertinent clinical applications are emphasized rather than attempting to cover everything included in the several large comprehensive texts available in our field. This "practical" approach should make it an essential guide to nuclear medicine physicians, technologists, students and interested clinicians alike.

Technetium-99m Pharmaceuticals

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Publisher : Springer Science & Business Media
ISBN 13 : 3540339906
Total Pages : 354 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Technetium-99m Pharmaceuticals by : Ilse Zolle

Download or read book Technetium-99m Pharmaceuticals written by Ilse Zolle and published by Springer Science & Business Media. This book was released on 2007-01-28 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioactive drug development is a multi-disciplinary task. Therefore, dedicated scientists and experts from different fields of specialisation have contributed to this book. The text reviews forty years of advances in radiopharmaceutical development based on Technetium. The first section reviews basic principles and analytic methods, and information on chemical makeup of radiopharmaceuticals. Part 2 reviews 99mTc-radiopharmaceuticals used in nuclear medicine, thoroughly outlining their chemistry, formulation, pharmacokinetics and clinical applications.

Fundamentals of Nuclear Medicine Dosimetry

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Publisher : Springer Science & Business Media
ISBN 13 : 0387745793
Total Pages : 241 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Fundamentals of Nuclear Medicine Dosimetry by : Michael G. Stabin

Download or read book Fundamentals of Nuclear Medicine Dosimetry written by Michael G. Stabin and published by Springer Science & Business Media. This book was released on 2008-01-15 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a leading international authority in the field, this book is ideal for physicians and residents in nuclear medicine who want to improve their knowledge in internal dosimetry. The text is a practical introduction that guides the reader through fundamental concepts in the calculation of radiation dose, including discussions of standardized models, methods of calculations, and available software applications. This comprehensive guide discusses too the biological effects of radiation on living systems. The book also includes an overview of regulatory aspects related to the radiation dosimetry of new radiopharmaceuticals.

Technetium-99m Radiopharmaceuticals

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Publisher :
ISBN 13 :
Total Pages : 378 pages
Book Rating : 4.:/5 (12 download)

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Book Synopsis Technetium-99m Radiopharmaceuticals by : IAEA.

Download or read book Technetium-99m Radiopharmaceuticals written by IAEA. and published by . This book was released on 2010 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technetium-99m radiopharmaceuticals will continue to have a significant impact in several areas of nuclear medicine. This publication is intended to provide a broad overview of the current status of technetium-99m radiopharmaceuticals. It includes chapters on the most advanced chemical techniques for labelling biomolecules and synthesizing suitable multifunctional ligands that will help in the development of specific radiotracers. Of special interest for the reader are details of recent research to develop technetium-99m tracers for monitoring different biological processes enabling the develo.

Molecular Imaging

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Publisher : Springer Science & Business Media
ISBN 13 : 3540767355
Total Pages : 379 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Molecular Imaging by : Shankar Vallabhajosula

Download or read book Molecular Imaging written by Shankar Vallabhajosula and published by Springer Science & Business Media. This book was released on 2009-07-13 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.

Targeted Molecular Imaging in Oncology

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Publisher : Springer Science & Business Media
ISBN 13 : 9780387950280
Total Pages : 322 pages
Book Rating : 4.9/5 (52 download)

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Book Synopsis Targeted Molecular Imaging in Oncology by : E. Edmund Kim

Download or read book Targeted Molecular Imaging in Oncology written by E. Edmund Kim and published by Springer Science & Business Media. This book was released on 2001 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer cells dedifferentiate with repect to cell function; their vascularity is more leaky, but perfusion is heterogenerously reduced, and interstitial fluid pressure is high, severely retarding delivery of agents from the blood. Targeted imaging is designed to produce a detectable difference between tissue that is visualized with single photon and positron emission tomography, magnetic resonance imaging, computed tomography, or ultrasonography. This book uniquely reports strategies for the application of molecular targeted imaging agents such as antibodies, peptides, receptors and contrast agents in the biologic grading of tumors, differential diagnosis of tumors, prediction of therapeutic response and monitoring tumor response to treatment. This book also describes updated information about the imaging of tumor angiogenesis, hypoxia, apoptosis and gene delivery as well as expression in the understanding and utility of tumor molecular biology for better cancer management.

Clinical Applications of SPECT/CT

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ISBN 13 : 9789201071088
Total Pages : 55 pages
Book Rating : 4.0/5 (71 download)

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Book Synopsis Clinical Applications of SPECT/CT by : International Atomic Energy Agency

Download or read book Clinical Applications of SPECT/CT written by International Atomic Energy Agency and published by . This book was released on 2008 with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrated single photon emission computed tomography and computed tomography (SPECT/CT) has emerged as an important diagnostic tool in medical imaging, where morphological markers are superimposed on anatomical images to allow a more thorough examination and higher levels of diagnostic accuracy. This TECDOC presents an overview of the SPECT/CT technology for use by nuclear medicine physicians, radiologists and clinical practitioners. The publication also covers the current medical status of SPECT/CT imaging, the role of this technology in the clinical management of patients and possible trends for future development.

Radiopharmaceuticals for Therapy

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Publisher : Springer
ISBN 13 : 8132226070
Total Pages : 357 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Radiopharmaceuticals for Therapy by : F. F. (Russ) Knapp

Download or read book Radiopharmaceuticals for Therapy written by F. F. (Russ) Knapp and published by Springer. This book was released on 2016-01-20 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides detailed information on therapeutic radiopharmaceuticals and discusses emerging technologies which have potential for broad clinical implementation. Recent advances in molecular biology, radiopharmaceutical chemistry and radioisotope production have stimulated a new era for the use of radiopharmaceuticals for targeted radionuclide therapy (TRT). Emerging clinical trials include use of peptides and monoclonal antibodies radiolabeled with therapeutic radionuclides for cancer therapy. In addition, small molecules are used for the treatment of chronic diseases such as metastatic bone pain palliation and radiation synovectomy of inflammatory joints. In the interventional arena, therapy of primary and metastatic liver cancer and arterial restenosis following angioplasty of both the coronary and peripheral arteries are being explored. Reactor and accelerator production of therapeutic radioisotopes is also integrated into these discussions. The development and use of radiopharmaceutical targeting characteristics required for treatment of specific disease processes and how these are implemented for radiopharmaceutical design strategies are also described. Radiopharmaceuticals for Therapy will benefit audiences in nuclear medicine and radionuclide therapy and will thus prove an invaluable source of up-to-date information for students, radiopharmaceutical scientists and professionals working in the radiopharmacy and nuclear medicine specialties.

Biological Dosimetry

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Publisher : Springer Science & Business Media
ISBN 13 : 3642693342
Total Pages : 343 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Biological Dosimetry by : W. G. Eisert

Download or read book Biological Dosimetry written by W. G. Eisert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: In October 1982, a small international symposium was held at the Gesellschaft fUr Strahlen- und Umweltforschung mbH (GSF) in Munich as a satellite meeting of the IX International Conference on Analytical Cytology. The symposium focussed on cytometric approaches to biological dosimetry, and was, to the best of our knowledge, the first meeting on this subject ever held. There was strong encouragement from the 75 attendees and from others to publish a proceedings of the symposium. Hence this book, containing 30 of the 36 presentations, has been assembled. Dosimetry, the accurate and systematic determination of doses, usually refers to grams of substance administered or rads of ionization or some such measure of exposure of a patient, a victim or an experimental system. The term also can be used to describe the quantity of an ultimate, active agent as delivered to the appropriate target material within a biological system. Thus, for mutagens, one can speak of DNA dosimetry, meaning the number of adducts produced in the DNA of target cells such as bone-mar row stem cells or spermatogonia.

Current Directions in Radiopharmaceutical Research and Development

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Publisher : Springer Science & Business Media
ISBN 13 : 9400917686
Total Pages : 248 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Current Directions in Radiopharmaceutical Research and Development by : Steven J. Mather

Download or read book Current Directions in Radiopharmaceutical Research and Development written by Steven J. Mather and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiophannaceutical research has recently undergone a major change in direction. In past years it has been concerned mainly with the development of perfusion tracers, the biodistribution of which reflect the regional blood flow to areas of major organs such as the heart and brain. However, a major new direction of interest now lies in the development of receptor-binding radio-tracers which can be used to perform in-vivo characterisation of diseased tissues and it is likely that much of the future research in this field will follow this direction. The difficulties in developing such tracers are considerable. The researcher must first identify a promising target for radiopharmaceutical development. High specific activity radioactive molecules must be designed and synthesised which will both bind to the target receptor with high affinity, and also have the physicochemical characteristics which will allow them to reach the target site in sufficient quantity while at the same time showing minimal uptake in non-target tissues. Thus the knowledge base required for radiophannaceutical development has now expanded beyond the limits of radiopharmaceutical chemistry to include aspects of biochemistry, molecular biology and conventional drug design. The portfolio of basic knowledge required to support current radiopharmaceutical development is changing and scientists working in this arena need to be trained in this regard. At the same time, the very latest developments in the field need to be communicated to the scientific community in order to stimulate the advancement of this exciting new direction of research.

Basic Sciences of Nuclear Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 3540859624
Total Pages : 420 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Basic Sciences of Nuclear Medicine by : Magdy Khalil

Download or read book Basic Sciences of Nuclear Medicine written by Magdy Khalil and published by Springer Science & Business Media. This book was released on 2010-10-26 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear medicine has become an ever-changing and expanding diagnostic and therapeutic medical profession. The day-to-day innovations seen in the field are, in great part, due to the integration of many scientific bases with complex technologic advances. The aim of this reference book, Basic Sciences of Nuclear Medicine, is to provide the reader with a comprehensive and detailed discussion of the scientific bases of nuclear medicine, covering the different topics and concepts that underlie many of the investigations and procedures performed in the field. Topics include radiation and nuclear physics, Tc-99m chemistry, single-photon radiopharmaceuticals and PET chemistry, radiobiology and radiation dosimetry, image processing, image reconstruction, quantitative SPECT imaging, quantitative cardiac SPECT, small animal imaging (including multimodality hybrid imaging, e.g., PET/CT, SPECT/CT, and PET/MRI), compartmental modeling, and tracer kinetics.

Basic Sciences of Nuclear Medicine

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Publisher : Springer Nature
ISBN 13 : 3030652459
Total Pages : 571 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Basic Sciences of Nuclear Medicine by : Magdy M. Khalil

Download or read book Basic Sciences of Nuclear Medicine written by Magdy M. Khalil and published by Springer Nature. This book was released on 2021-05-26 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive and detailed information on the scientific bases of nuclear medicine, addressing a wide variety of topics and explaining the concepts that underlie many of the investigations and procedures performed in the field. The book is divided into six sections that cover the physics and chemistry of nuclear medicine besides associated quality assurance/quality control procedures; dosimetry and radiation biology; SPECT and PET imaging instrumentation plus CT imaging technology in hybrid modalities; data analysis including image processing, reconstruction, radiomics, image degrading correction techniques, along with image quantitation and kinetic modeling. Within these sections, particular attention is paid to recent developments and the advances in knowledge that have taken place since release of the first edition in 2011. Several entirely new chapters have been included and the remaining chapters, thoroughly updated. Innovations in the ever-expanding field of nuclear medicine are predominantly due to integration of the basic sciences with complex technological advances. This excellently illustrated book on the subject will be of interest to not only nuclear medicine physicists and physicians but also clinical scientists, radiologists, radiopharmacists, medical students and technologists.

Radioguided Surgery

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Publisher : Springer Science & Business Media
ISBN 13 : 0387383271
Total Pages : 319 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Radioguided Surgery by : Giuliano Mariani

Download or read book Radioguided Surgery written by Giuliano Mariani and published by Springer Science & Business Media. This book was released on 2010-05-10 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multidisciplinary textbook is designed to be the standard on the subject and is geared for use by physicians who are involved in the care and/or diagnosis of cancer patients. Comprehensive coverage is provided on all aspects of radioguided surgery. Practical information is readily accessible and throughout there is an emphasis on improved decision making. Tables present the indications, performance, and interpretation of procedures at a glance. A wealth of illustrations, including a full-color insert, enhances the application of new concepts.

Nuclear Hepatology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642006485
Total Pages : 365 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Nuclear Hepatology by : Gerbail T. Krishnamurthy

Download or read book Nuclear Hepatology written by Gerbail T. Krishnamurthy and published by Springer Science & Business Media. This book was released on 2009-06-23 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition of Nuclear Hepatology almost 10 years ago, new advances have taken place, both in our understanding of liver pathophysiology and various imaging modalities. A unique feature of imaging of physiology is that it enables quanti- cation. Since liver physiology is complex, quantification has been a challenge. Many p- lications in the past have often included quantification based on home-made software not available for others. Thus, the comparison of results from one center to another becomes difficult, if not impossible. The second edition of Nuclear Hepatology addresses these issues. Sophisticated software for liver and gallbladder function has been tested and va- dated through many of our previous publications. Now that software is FDA approved and available for others through a commercial company, it is hoped that future publications of imaging of liver and gallbladder physiology would routinely include quantification. Although the function of the hepatocyte is complex, it can be broadly divided into two main categories, substrate uptake at the basolateral border and intracellular transit prior to excretion into the canaliculi. The earliest manifestation of hepatocellular injury occurs in the form of prolongation of the intracellular transit time, which occurs long before the disruption of the basolateral border with subsequent rupture and death. The liver enzymes are released into circulation after the death of the hepatocyte.