Bioinformatics Of The Brain

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Bioinformatics of the Brain

Author : Kayhan Erciyes
Publisher : CRC Press
ISBN 13 : 1040117414
Total Pages : 305 pages
Book Rating : 4.0/5 (41 download)

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Book Synopsis Bioinformatics of the Brain by : Kayhan Erciyes

Download or read book Bioinformatics of the Brain written by Kayhan Erciyes and published by CRC Press. This book was released on 2024-09-25 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain consisting of billions of neurons is probably the most complex and mysterious organ of the body. Understanding the functioning of the brain in its health and disease states has baffled the researchers working in this area for many years. The diversity of brain diseases and disorders makes the analysis of brain functions an even more challenging area of research. In vitro and in vivo studies regarding the brain may be laborious, however, bioinformatics using in silico approaches may take the burden off the experimental studies and give us a clearer perspective on disease and healthy states of the brain, its functions, and disease mechanisms. Recent advancements in neuroimaging technologies, the development of high-performance computers and the development of software, algorithms and methods to analyze data obtained from various neuroimaging processes have opened new frontiers in neuroscience enabling unprecedented finer analysis of the brain functions. This relatively new approach of brain analysis which may be termed Bioinformatics of the Brain is the main subject of this volume aiming to provide a thorough review of various bioinformatics approaches for analyzing the functioning of the brain and understanding brain diseases such as neurodegenerative diseases, brain tumors, and neuropsychiatric disorders. Authors from various disciplines in this volume each focus on a different aspect aiming to expand our understanding of this area of research. Topics included are: Brain diseases and disorders Stem cell therapy of neurodegenerative diseases Tissue engineering applications of gliomas Brain tumor detection and modeling Brain tumor growth simulation Brain-computer interface Bioinformatics of brain diseases Graph-theoretical analysis of complex brain networks Brain proteomics This book is intended to aid scientists, researchers, and graduate students in carrying out interdisciplinary research in the areas of bioinformatics, bioengineering, computer engineering, software engineering, mathematics, molecular biology, genetics, and biotechnology.

Ecology of the Brain

Author : Thomas Fuchs
Publisher : Oxford University Press
ISBN 13 : 0199646880
Total Pages : 371 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Ecology of the Brain by : Thomas Fuchs

Download or read book Ecology of the Brain written by Thomas Fuchs and published by Oxford University Press. This book was released on 2018 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Present day neuroscience places the brain at the centre of study. But what if researchers viewed the brain not as the foundation of life, rather as a mediating organ? Ecology of the Brain addresses this very question. It considers the human body as a collective, a living being which uses the brain to mediate interactions. Those interactions may be both within the human body and between the human body and its environment. Within this framework, the mind is seen not as a product of the brain but as an activity of the living being; an activity which integrates the brain within the everyday functions of the human body. Going further, Fuchs reformulates the traditional mind-brain problem, presenting it as a dual aspect of the living being: the lived body and the subjective body - the living body and the objective body. The processes of living and experiencing life, Fuchs argues, are in fact inextricably linked; it is not the brain, but the human being who feels, thinks and acts. For students and academics, Ecology of the Brain will be of interest to those studying or researching theory of mind, social and cultural interaction, psychiatry, and psychotherapy.

Evolving Connectionist Systems

Author : Nikola K. Kasabov
Publisher : Springer Science & Business Media
ISBN 13 : 1846283477
Total Pages : 465 pages
Book Rating : 4.8/5 (462 download)

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Book Synopsis Evolving Connectionist Systems by : Nikola K. Kasabov

Download or read book Evolving Connectionist Systems written by Nikola K. Kasabov and published by Springer Science & Business Media. This book was released on 2007-08-23 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of the must-read work in the field presents generic computational models and techniques that can be used for the development of evolving, adaptive modeling systems, as well as new trends including computational neuro-genetic modeling and quantum information processing related to evolving systems. New applications, such as autonomous robots, adaptive artificial life systems and adaptive decision support systems are also covered.

Databasing the Brain

Author : Steven H. Koslow
Publisher :
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Databasing the Brain by : Steven H. Koslow

Download or read book Databasing the Brain written by Steven H. Koslow and published by . This book was released on 2005-03-10 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers both basic principles and specific applications across a range of problems in brain research. It truly integrates neuroscience with informatics, providing a means for understanding the new analytical tools and models of neuronal functions now being developed. Each chapter offers practical guidance for applying this knowledge to current research, enhancing electronic collaborations, and formulating hypotheses.

Neuroscience Databases

Author : Rolf Kötter
Publisher : Springer Science & Business Media
ISBN 13 : 9781402071652
Total Pages : 340 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Neuroscience Databases by : Rolf Kötter

Download or read book Neuroscience Databases written by Rolf Kötter and published by Springer Science & Business Media. This book was released on 2003 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroscience Databases: A Practical Guide is the first book providing a comprehensive overview of these increasingly important databases. This volume makes the results of the Human Genome Project and other recent large-scale initiatives in the neurosciences available to a wider community. It extends the scope of bioinformatics from the molecular to the cellular, microcircuitry and systems levels, dealing for the first time with complex neuroscientific issues and leading the way to a new culture of data sharing and data mining necessary to successfully tackle neuroscience questions. Aimed at the novice user who wants to access the data, it provides clear and concise instructions on how to download the available data sets and how to use the software with a minimum of technical detail with most chapters written by the database creators themselves. Key databases and topics include: -Neuroinformatics for C. Elegans; -Gene Expression Patterns; -Functional Analyses of Olfactory Receptors -Protein-Protein Interactions; -Web-Based Neuronal Archives; -Neuronal and Network Modeling; -Storage and Retrieval of Experimental Data for Biophysically Realistic Modeling; -Analysis of Spike Trains; -Neural Connectivity Patterns; -Software Tools for Neuroimaging; -Data Management, Inspection and Sharing.

Bioinformatics Applied to Neuroscience

Author : Thayne Kowalski
Publisher : Frontiers Media SA
ISBN 13 : 2832536395
Total Pages : 214 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Bioinformatics Applied to Neuroscience by : Thayne Kowalski

Download or read book Bioinformatics Applied to Neuroscience written by Thayne Kowalski and published by Frontiers Media SA. This book was released on 2023-10-25 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bioinformatics and Computational Biology

Author : Basant K. Tiwary
Publisher : Springer Nature
ISBN 13 : 9811642419
Total Pages : 239 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Bioinformatics and Computational Biology by : Basant K. Tiwary

Download or read book Bioinformatics and Computational Biology written by Basant K. Tiwary and published by Springer Nature. This book was released on 2021-11-23 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook introduces fundamental concepts of bioinformatics and computational biology to the students and researchers in biology, medicine, veterinary science, agriculture, and bioengineering . The respective chapters provide detailed information on biological databases, sequence alignment, molecular evolution, next-generation sequencing, systems biology, and statistical computing using R. The book also presents a case-based discussion on clinical, veterinary, agricultural bioinformatics, and computational bioengineering for application-based learning in the respective fields. Further, it offers readers guidance on reconstructing and analysing biological networks and highlights computational methods used in systems medicine and genome-wide association mapping of diseases. Given its scope, this textbook offers an essential introductory book on bioinformatics and computational biology for undergraduate and graduate students in the life sciences, botany, zoology, physiology, biotechnology, bioinformatics, and genomic science as well as systems biology, bioengineering and the agricultural, and veterinary sciences.

The OMICs

Author : Giovanni Coppola
Publisher : Oxford University Press
ISBN 13 : 0199855455
Total Pages : 385 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis The OMICs by : Giovanni Coppola

Download or read book The OMICs written by Giovanni Coppola and published by Oxford University Press. This book was released on 2014 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: The OMICs:Applications in Neuroscience summarizes the state of the art in OMICs applications in neurology and neuroscience, attracting neurologists who are interested in the progress of this field towards clinical applications, and neuroscientists who may be not familiar with the most recent advances in this ever-changing field. The book will include an overview of most relevant high-throughput approaches (collectively known as 'OMICs') and how they relate to neurology and neuroscience. The explosion of high-throughput assays has introduced large datasets, computational servers, and bioinformatics approaches to neuroscience and medicine in general. The reader will be provided with an overview of the application or method, a perspective on the current and future applications in neurology and neuroscience, and a few published examples illustrating possible practical use. Emerging topics such as ethical issues related to personal genome sequencing, epigenetics, network analysis, and role of peripheral biomarkers in disease diagnosis and follow-up will be covered as well.

Data Analytics in Bioinformatics

Author : Rabinarayan Satpathy
Publisher : John Wiley & Sons
ISBN 13 : 111978560X
Total Pages : 433 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Data Analytics in Bioinformatics by : Rabinarayan Satpathy

Download or read book Data Analytics in Bioinformatics written by Rabinarayan Satpathy and published by John Wiley & Sons. This book was released on 2021-01-20 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel machine learning computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics approximating classification and prediction of disease, feature selection, dimensionality reduction, gene selection and classification of microarray data and many more.

Micro-, Meso- and Macro-Dynamics of the Brain

Author : György Buzsáki
Publisher : Springer
ISBN 13 : 3319288024
Total Pages : 181 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Micro-, Meso- and Macro-Dynamics of the Brain by : György Buzsáki

Download or read book Micro-, Meso- and Macro-Dynamics of the Brain written by György Buzsáki and published by Springer. This book was released on 2016-05-02 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The individual chapters cover several fascinating facets of contemporary neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Each of these topics require appropriate levels of analyses with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks, supplemented by models and theories to explain how different levels of brain dynamics interact with each other and how the failure of such interactions results in neurologic and mental disease. While such complex questions cannot be answered exhaustively by a dozen or so chapters, this volume offers a nice synthesis of current thinking and work-in-progress on micro-, meso- and macro- dynamics of the brain.

Demystifying the Brain

Author : V. Srinivasa Chakravarthy
Publisher : Springer
ISBN 13 : 9811333203
Total Pages : 389 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Demystifying the Brain by : V. Srinivasa Chakravarthy

Download or read book Demystifying the Brain written by V. Srinivasa Chakravarthy and published by Springer. This book was released on 2018-12-07 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an emerging new vision of the brain, which is essentially expressed in computational terms, for non-experts. As such, it presents the fundamental concepts of neuroscience in simple language, without overwhelming non-biologists with excessive biological jargon. In addition, the book presents a novel computational perspective on the brain for biologists, without resorting to complex mathematical equations. It addresses a comprehensive range of topics, starting with the history of neuroscience, the function of the individual neuron, the various kinds of neural network models that can explain diverse neural phenomena, sensory-motor function, language, emotions, and concluding with the latest theories on consciousness. The book offers readers a panoramic introduction to the “new brain” and a valuable resource for interdisciplinary researchers looking to gatecrash the world of neuroscience.

Neuroinformatics for Neuropsychology

Author : Vinoth Jagaroo
Publisher : Springer Science & Business Media
ISBN 13 : 1441900608
Total Pages : 133 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Neuroinformatics for Neuropsychology by : Vinoth Jagaroo

Download or read book Neuroinformatics for Neuropsychology written by Vinoth Jagaroo and published by Springer Science & Business Media. This book was released on 2009-08-11 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics involves specialized application of computer technology to investigative and conceptual problems in biology and medicine; neuroinformatics (NI) is the practice of bioinformatics in the neurosciences. Over the past two decades the biomedical sciences have been revolutionized by databases, data mining and data modeling techniques. The Human Genome Project, which depended on informatics methods, has been the most well recognized bioinformatics undertaking. Bioinformatics has since been applied all across biology and medicine, and has also transformed almost every avenue in neuroscience. Yet in neuropsychology, NI perspectives remain largely unrealized. Ironically, NI offers enormous potential to the essential praxis of neuropsychology - assessing cognitive behavior and relating cognition to neural systems. Neuroinformatics can be applied to neuropsychology as richly as it has been applied across the neurosciences. Neuroinformatics for Neuropsychology is the first book to explain the relevance and value of NI to neuropsychology. It systematically describes NI tools, applications and models that can enhance the efforts of neuropsychologists. It also describes the implications of NI for neuropsychology in the 21st century – fundamental shifts away from the conventional modes of research, practice and communication that have thus far characterized the field. One of the foremost experts on the subject: Illustrates the vital role NI is playing throughout the neurosciences. Provides a sampling of NI tools and applications in neuroscience research, and lays out current organization structures that support NI. Describes the lack of NI in neuropsychology, differentiates between NI systems for neuropsychology and conventional computerized assessment methods, and proposes criteria for neuropsychology-specific NI systems. Describes NI applications and models currently in use in neuropsychology, and NI models for neuropsychology that are being pioneered in phenomics research. Discusses potential obstacles and aids to NI in neuropsychology, including issues such as data sharing, standardization of methods, and data ontology. Projects the future of neuropsychological research and practice in light of the new generation of the internet, Web 2.0, geared to collective knowledge building. A vital introduction to a profound technological practice, Neuroinformatics for Neuropsychology is important reading for clinical neuropsychologists, cognitive neuroscientists, behavioral neurologists, and speech-language pathologists. Researchers, clinicians, and graduate students interested in informatics for the brain-behavioral sciences will especially welcome this unique volume.

Evolution of Translational Omics

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309224187
Total Pages : 354 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Evolution of Translational Omics by : Institute of Medicine

Download or read book Evolution of Translational Omics written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Essentials of Structural Equation Modeling

Author : Mustafa Emre Civelek
Publisher : Lulu.com
ISBN 13 : 1609621298
Total Pages : 120 pages
Book Rating : 4.6/5 (96 download)

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Book Synopsis Essentials of Structural Equation Modeling by : Mustafa Emre Civelek

Download or read book Essentials of Structural Equation Modeling written by Mustafa Emre Civelek and published by Lulu.com. This book was released on 2018-03-12 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Structural Equation Modeling is a statistical method increasingly used in scientific studies in the fields of Social Sciences. It is currently a preferred analysis method, especially in doctoral dissertations and academic researches. Many universities do not include this method in the curriculum, so students and scholars try to solve these problems using books and internet resources. This book aims to guide the researcher in a way that is free from math expressions. It teaches the steps of a research program using structured equality modeling practically. For students writing theses and scholars preparing academic articles, this book aims to analyze systematically the methodology of studies conducted using structural equation modeling methods in the social sciences. In as simple language as possible, it conveys basic information. It consists of two parts: the first gives basic concepts of structural equation modeling, and the second gives examples of applications.

Bioinformatics

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309072565
Total Pages : 54 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Bioinformatics by : National Research Council

Download or read book Bioinformatics written by National Research Council and published by National Academies Press. This book was released on 2000-12-01 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this workshop was to bring together bioinformatics stake holders from government, academe, and industry for a day of presentations and dialogue. Fifteen experts identified and discussed some of the most important issues raised by the current flood of biologic data. Topics explored included the importance of database curation, database integration and interoperability, consistency and standards in terminology, error prevention and correction, data provenance, ontology, the importance of maintaining privacy, data mining, and the need for more computer scientists with specialty training in bioinformatics. Although formal conclusions and recommendations will not come from this particular workshop, many insights may be gleaned about the future of this field, from the context of the discussions and presentations described here.

Application of Bioinformatics in Cancers

Author : Chad Brenner
Publisher : MDPI
ISBN 13 : 3039217887
Total Pages : 418 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Application of Bioinformatics in Cancers by : Chad Brenner

Download or read book Application of Bioinformatics in Cancers written by Chad Brenner and published by MDPI. This book was released on 2019-11-20 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of 25 research papers comprised of 22 original articles and 3 reviews is brought together from international leaders in bioinformatics and biostatistics. The collection highlights recent computational advances that improve the ability to analyze highly complex data sets to identify factors critical to cancer biology. Novel deep learning algorithms represent an emerging and highly valuable approach for collecting, characterizing and predicting clinical outcomes data. The collection highlights several of these approaches that are likely to become the foundation of research and clinical practice in the future. In fact, many of these technologies reveal new insights about basic cancer mechanisms by integrating data sets and structures that were previously immiscible. Accordingly, the series presented here bring forward a wide range of artificial intelligence approaches and statistical methods that can be applied to imaging and genomics data sets to identify previously unrecognized features that are critical for cancer. Our hope is that these articles will serve as a foundation for future research as the field of cancer biology transitions to integrating electronic health record, imaging, genomics and other complex datasets in order to develop new strategies that improve the overall health of individual patients.

The Orbitofrontal Cortex

Author : Edmund T. Rolls
Publisher :
ISBN 13 : 0198845995
Total Pages : 318 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis The Orbitofrontal Cortex by : Edmund T. Rolls

Download or read book The Orbitofrontal Cortex written by Edmund T. Rolls and published by . This book was released on 2019 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'The Orbitofrontal Cortex' explores a part of the brain that is important in human emotion, pleasure, decision-making, valuation, and personality. The book is unique in providing a coherent multidisciplinary approach to understanding the functions of one of the most interesting regions of the human brain, in both health and in disease.