Bioimaging In Neurodegeneration

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Bioimaging in Neurodegeneration

Author : Patricia A. Broderick
Publisher : Springer Science & Business Media
ISBN 13 : 1592598889
Total Pages : 314 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Bioimaging in Neurodegeneration by : Patricia A. Broderick

Download or read book Bioimaging in Neurodegeneration written by Patricia A. Broderick and published by Springer Science & Business Media. This book was released on 2007-11-05 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioimaging is in the forefront of medicine for the diagnosis and helps to predict the progression of AD via mild cognitive treatment of neurodegenerative disease. Conventional magnetic impairment (MCI) studies. resonance imaging (MRI) uses interactive external magnetic fields Novel neuroimaging technologies, such as neuromolecular and resonant frequencies of protons from water molecules. imaging (NMI) with a series of newly developed BRODERICK ® However, newer sequences, such as magnetization-prepared rapid PROBE sensors, directly image neurotransmitters, precursors, acquisition gradient echo (MPRAGE), are able to seek higher and metabolites in vivo, in real time and within seconds, at separate levels of anatomic resolution by allowing more rapid temporal and selective waveform potentials. NMI, which uses an imaging. Magnetic resonance spectroscopy (MRS) images electrochemical basis for detection, enables the differentiation of metabolic changes, enabling underlying pathophysiologic neurodegenerative diseases in patients who present with mesial dysfunction in neurodegeneration to be deciphered. Neuro- versus neocortical temporal lobe epilepsy. In fact, NMI has some 1 chemicals visible with proton H MRS include N-acetyl aspartate remarkable similarities to MRI insofar as there is technological (NAA), creatine/phosphocreatine (Cr), and choline (Cho); NAA dependence on electron and proton transfer, respectively, and is considered to act as an in vivo marker for neuronal loss and/or further dependence is seen in both NMI and MRI on tissue neuronal dysfunction. By extending imaging to the study of composition such as lipids.

Multimodal and Longitudinal Bioimaging Methods for Characterizing the Progressive Course of Dementia

Author : Javier Ramírez
Publisher : Frontiers Media SA
ISBN 13 : 2889459497
Total Pages : 168 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Multimodal and Longitudinal Bioimaging Methods for Characterizing the Progressive Course of Dementia by : Javier Ramírez

Download or read book Multimodal and Longitudinal Bioimaging Methods for Characterizing the Progressive Course of Dementia written by Javier Ramírez and published by Frontiers Media SA. This book was released on 2019-08-12 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Imaging in Neurodegenerative Disorders

Author : Luca Saba
Publisher : OUP Oxford
ISBN 13 : 0191651397
Total Pages : 640 pages
Book Rating : 4.1/5 (916 download)

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Book Synopsis Imaging in Neurodegenerative Disorders by : Luca Saba

Download or read book Imaging in Neurodegenerative Disorders written by Luca Saba and published by OUP Oxford. This book was released on 2015-01-08 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosing neurodegenerative diseases can prove particularly intimidating to clinicians, because many times the diagnosis cannot be critically "confirmed" by a simple test. New imaging modalities have advanced to the point of high resolution, morphological, metabolic and functional analysis. Computed tomography, magnetic resonance, nuclear medicine and molecular imaging have recently emerged as outstanding non-invasive techniques for the study of the neurodegenerative disorders. Imaging in Neurodegenerative Disorders covers all the imaging techniques and new exciting methods like new tracers, biomarker, metabolomic and gene-array profiling, potential for applying such techniques clinically, and offers present and future applications as applied to the neurodegenerative disorders with the most world renowned scientists in these fields. This book is an invaluable resource for researchers, clinicians, and trainees in neuroscience, neurology, psychiatry, and radiology.

Imaging of Neurodegenerative Disorders

Author : Sangam Kanekar
Publisher : Thieme
ISBN 13 : 1638532559
Total Pages : 1175 pages
Book Rating : 4.6/5 (385 download)

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Book Synopsis Imaging of Neurodegenerative Disorders by : Sangam Kanekar

Download or read book Imaging of Neurodegenerative Disorders written by Sangam Kanekar and published by Thieme. This book was released on 2015-11-05 with total page 1175 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive reference on imaging and diagnosis of neurodegenerative diseases FIVE STARS from Doody's Star Ratings™ Imaging of Neurodegenerative Disorders is a comprehensive, up-to-date reference covering the latest techniques used in neuroimaging as well as the basic structural imaging that facilitates diagnosis of various neurodegenerative disorders. All advanced imaging modalities, including MR spectroscopy, DTI, MRI, and PET scans, are discussed in detail, enabling readers to gain a solid understanding of how to use them to diagnose neurodegenerative diseases. Key Features: Each chapter covers the clinical features, pathology, and imaging of a specific disease/disorder Sections on cerebellar degeneration and dysfunction, motor neuron disorders, post-traumatic cognitive disorders, dementia with extrapyramidal syndromes, and deep brain stimulation A final section discusses the distinctions between preventable, potentially reversible, and irreversible dementia This book provides radiologists and all who care for patients suffering from neurodegenerative diseases with an invaluable reference that will be part of their medical library for many years to come.

Biomedical Imaging in Experimental Neuroscience

Author : Nick Van Bruggen
Publisher : CRC Press
ISBN 13 : 1420042157
Total Pages : 368 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Biomedical Imaging in Experimental Neuroscience by : Nick Van Bruggen

Download or read book Biomedical Imaging in Experimental Neuroscience written by Nick Van Bruggen and published by CRC Press. This book was released on 2002-12-23 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen an explosion of activity in the field of biomedical imaging in an attempt to understand the behavior of the brain in healthy and disease states. With the emergence of genetically manipulated laboratory mice and the knowledge of the mouse genome, we are entering an exciting new era with revolutionary tools for experimental research. Noninvasive imaging techniques capable of providing both anatomical and functional descriptions of the brain have become essential. Among the various imaging methodologies, magnetic resonance imaging (MRI) stands in the forefront by virtue of its contrast versatility and pathophysiological specificity. Emphasizing the relationship between physiological microenvironment and macroscopic imaging signal changes, Biomedical Imaging in Experimental Neuroscience presents a comprehensive review of the noninvasive biomedical imaging techniques available for laboratory animal research. Focusing on MRI, but recognizing the multiple forms of imaging information, this book outlines the scope and limitations of these methods and analyzes their impact on in vivo neuroscience research. The book is intended for the biologist who may not have a background in the physical sciences. This applied guide also provides a concise theoretical description of the pertinent physics. Noninvasive imaging offers the obvious benefits of reducing sample sizes and identifying new and unanticipated behaviors. Biomedical Imaging in Experimental Neuroscience presents detailed information for biologists interested in how biomedical imaging may augment their in vivo research and for clinical practitioners seeking deeper insights into the association between imaging findings and disease pathophysiology.

Biomedical Imaging in Experimental Neuroscience

Author : Nick Van Bruggen
Publisher : CRC Press
ISBN 13 : 9781420042153
Total Pages : 396 pages
Book Rating : 4.0/5 (421 download)

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Book Synopsis Biomedical Imaging in Experimental Neuroscience by : Nick Van Bruggen

The Neuroscience of Parkinson's Disease

Author : Colin R Martin
Publisher : Academic Press
ISBN 13 : 0128159596
Total Pages : 1548 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Neuroscience of Parkinson's Disease by : Colin R Martin

Download or read book The Neuroscience of Parkinson's Disease written by Colin R Martin and published by Academic Press. This book was released on 2020-12-21 with total page 1548 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neuroscience of Parkinson’s Disease (two volume set) provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. The book also fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson’s disease—from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field. Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations Serves as a "one-stop" source for everything you need to know about Parkinson’s disease

Neurodegeneration

Author : Giovanni Manfredi
Publisher : Humana Press
ISBN 13 : 9781617793295
Total Pages : 512 pages
Book Rating : 4.7/5 (932 download)

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Book Synopsis Neurodegeneration by : Giovanni Manfredi

Download or read book Neurodegeneration written by Giovanni Manfredi and published by Humana Press. This book was released on 2011-09-15 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurodegenerative disorders, such as Alzheimer's and Parkinson's disease are a growing burden on our society. Understanding and treating these common diseases is one of the major current challenges for the biomedical field. In Neurodegeneration: Methods and Protocols, experts in the field tackle this challenge and present cutting-edge analytical and technological approaches to study the mechanisms underlying neurodegenerative processes. Organizes into five sections, chapters detail protocols for isolating and culturing cells from the nervous system, production and use of animal models, characterization of cell death, analytical tools to study disease mechanisms, and therapeutic approaches for neurodegeneration. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Neurodegeneration: Methods and Protocols serves as an ideal guide to both novice and professional researchers in the field of neurodegeneration.

The Biochemistry of Amyloids in Neurodegenerative Diseases, Volume I

Author : Cláudio M. Gomes
Publisher : Frontiers Media SA
ISBN 13 : 2889742512
Total Pages : 153 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis The Biochemistry of Amyloids in Neurodegenerative Diseases, Volume I by : Cláudio M. Gomes

Download or read book The Biochemistry of Amyloids in Neurodegenerative Diseases, Volume I written by Cláudio M. Gomes and published by Frontiers Media SA. This book was released on 2022-02-02 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nanomedical Drug Delivery for Neurodegenerative Diseases

Author : Awesh K. Yadav
Publisher : Academic Press
ISBN 13 : 0323898017
Total Pages : 284 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Nanomedical Drug Delivery for Neurodegenerative Diseases by : Awesh K. Yadav

Download or read book Nanomedical Drug Delivery for Neurodegenerative Diseases written by Awesh K. Yadav and published by Academic Press. This book was released on 2022-03-10 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomedical Drug Delivery for Neurodegenerative Diseases opens the door for promising approaches and advances in the diagnosis and treatment of various neurodegenerative diseases. The contents of the book comprise all the aspects related to the design, synthesis, and application of different nanodrug delivery systems in the treatment of neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases. This book explores how nanoparticulate drug carriers can improve therapeutic efficacy by selecting a suitable design strategy. Nanomedical Drug Delivery for Neurodegenerative Diseases is a valuable resource for graduates, clinical researchers, and other scientists working to minimize the challenges to deliver the drugs and genes in a more efficient and targeted manner for the treatment of neurodegenerative diseases. Includes design, synthesis and applications of drug delivery systems Explores the role of nanotechnology in the diagnosis and treatment of neurodegenerative disorders Reviews applications for the management of Parkinson's disease, Alzheimer's disease, Huntington's disease, and motor neuron diseases Discusses extracellular vesicles and mitochondria-targeted bioactive delivery systems Details how nanocarrier-based delivery is useful to improve efficacy and cure

Quantitative Magnetic Resonance Imaging

Author : Nicole Seiberlich
Publisher : Academic Press
ISBN 13 : 0128170581
Total Pages : 1094 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Quantitative Magnetic Resonance Imaging by : Nicole Seiberlich

Download or read book Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and published by Academic Press. This book was released on 2020-11-18 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Magnetic Resonance Imaging is a ‘go-to’ reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: The basic physics behind tissue property mapping How to implement basic pulse sequences for the quantitative measurement of tissue properties The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* The pros and cons for different approaches to mapping perfusion The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor maps and more complex representations of diffusion How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance Fingerprinting can be used to accelerate or improve tissue property mapping schemes How tissue property mapping is used clinically in different organs Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches

Biological Synthesis of Nanoparticles and Their Applications

Author : L Karthik
Publisher : CRC Press
ISBN 13 : 0429555784
Total Pages : 299 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Biological Synthesis of Nanoparticles and Their Applications by : L Karthik

Download or read book Biological Synthesis of Nanoparticles and Their Applications written by L Karthik and published by CRC Press. This book was released on 2019-12-06 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Synthesis of Nanoparticles and Their Applications gives insight into the synthesis of nanoparticles utilizing the natural routes. It demonstrates various strategies for the synthesis of nanoparticles utilizing plants, microscopic organisms like bacteria, fungi, algae and so forth. It orchestrates interdisciplinary hypothesis, ideas, definitions, models and discoveries associated with complex cell of the prokaryotes and eukaryotes. Highlights: Discusses biological approach towards the nanoparticle synthesis Describes the role of nanotechnology in the field of medicine and its medical devices Covers application and usage of the chemicals at the molecular level to act as catalysts and binding products for both organic and inorganic Chemical Reactions Reviews application in physics such as solar cells, photovoltaics and other usage Microorganisms can aggregate and detoxify substantial metals because of different reductase enzymes, which can diminish metal salts to metal nanoparticles. The readers after going through this book will have detailed account of mechanism of bio-synthesis of nanoparticles.

Physics of Biological Oscillators

Author : Aneta Stefanovska
Publisher : Springer Nature
ISBN 13 : 3030598055
Total Pages : 431 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Physics of Biological Oscillators by : Aneta Stefanovska

Download or read book Physics of Biological Oscillators written by Aneta Stefanovska and published by Springer Nature. This book was released on 2021-05-05 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, based on a selection of invited presentations from a topical workshop, focusses on time-variable oscillations and their interactions. The problem is challenging, because the origin of the time variability is usually unknown. In mathematical terms, the oscillations are non-autonomous, reflecting the physics of open systems where the function of each oscillator is affected by its environment. Time-frequency analysis being essential, recent advances in this area, including wavelet phase coherence analysis and nonlinear mode decomposition, are discussed. Some applications to biology and physiology are described. Although the most important manifestation of time-variable oscillations is arguably in biology, they also crop up in, e.g. astrophysics, or for electrons on superfluid helium. The book brings together the research of the best international experts in seemingly very different disciplinary areas.

Neuropathology of Drug Addictions and Substance Misuse Volume 2

Author : Victor R. Preedy
Publisher : Academic Press
ISBN 13 : 0128003758
Total Pages : 1182 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Neuropathology of Drug Addictions and Substance Misuse Volume 2 by : Victor R. Preedy

Download or read book Neuropathology of Drug Addictions and Substance Misuse Volume 2 written by Victor R. Preedy and published by Academic Press. This book was released on 2016-03-25 with total page 1182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects is the second of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader’s knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 2 addresses stimulants, club and dissociative drugs, hallucinogens, and inhalants and solvents. Each section provides data on the general, molecular and cellular, and structural and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention, and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad material and substances. Offers a modern approach to understanding the pathology of substances of abuse, offering an evidence-based ethos for understanding the neurology of addictions Fills an existing gap in the literature by serving as a “one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse Includes in each chapter: list of abbreviations, abstract, introduction, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and from the genome to whole body

Biomedical Nanostructures

Author : Kenneth Gonsalves
Publisher : John Wiley & Sons
ISBN 13 : 0470185821
Total Pages : 543 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis Biomedical Nanostructures by : Kenneth Gonsalves

Download or read book Biomedical Nanostructures written by Kenneth Gonsalves and published by John Wiley & Sons. This book was released on 2007-11-09 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to Use Nanoscale Materials to Design Novel Biomedical Devices and Applications Discover how to take full advantage of nanoscale materials in the design and fabrication of leading-edge biomedical devices. The authors introduce you to a variety of possible clinical applications such as drug delivery, diagnostics, and cancer therapy. In addition, the authors explore the interface between micron and nanoscale materials for the development of applications such as tissue engineering. Finally, they examine the mechanisms of cell interactions with material surfaces through the use of nanotechnology-based material processing and characterization methods. The text's three sections highlight its interdisciplinary approach: * Part One: Nanostructure Fabrication * Part Two: Bio-Nano Interfaces * Part Three: Clinical Applications of Nanostructures Among the key topics covered are nanotechnology in tissue regeneration; biomolecular engineering; receptor-ligand interactions; cell-biomaterial interactions; nanomaterials in diagnostics, drug delivery, and cancer therapy; and nano- and micron-level engineering and fabrication. Throughout the text, clear examples guide you through the chemistry and the processing involved in designing and developing nanoscale materials for biomedical devices. Each chapter begins with an introduction and ends with a conclusion highlighting the key points. In addition, references at the end of the chapter help you expand your research on any individual topic. In summary, this book helps biomedical researchers and engineers understand the physical phenomena that occur at the nanoscale in order to design novel cell-based constructs for a wide range of applications.

Metal Ions in Bio-Imaging Techniques

Author : Astrid Sigel
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110685787
Total Pages : 666 pages
Book Rating : 4.1/5 (16 download)

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Book Synopsis Metal Ions in Bio-Imaging Techniques by : Astrid Sigel

Download or read book Metal Ions in Bio-Imaging Techniques written by Astrid Sigel and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-03-08 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 22, entitled Metal Ions in Bio-Imaging Techniques, of the series Metal Ions in Life Sciences deals with metal ions as tools in imaging. This dates back to the first half of the past century, when barium sulfate was orally given to patients undergoing X-ray examination. The use of contrast agents has since developed into a large interdisciplinary field encompassing not only medicine, but also chemistry, material sciences, physics, biology, engineering, and computer sciences. MILS-22 provides deep and current insights in 17 stimulating chapters on the new research frontiers of this fast growing field on bio-imaging ... and beyond. For example, adding bio-sensing yields theranostic agents, meaning diagnosis and therapy linked in the same molecule; ions of Gd, Mn, Fe, Co, Ir, 99mTc, etc., are involved. Other important topics are, e.g., metal complexes in paramagnetic Chemical Exchange Transfer (paraCEST), radiometals for Positron Emission Tomography (PET) imaging, or paramagnetic metal ion probes for 19F magnetic resonance imaging. MILS-22 is written by 57 internationally recognized experts from 12 countries, that is, from the US via Europe to China. The impact of this vibrant research area is manifested by more than 2300 references and nearly 120 figures, mostly in color, and several informative tables. To conclude, Metal Ions in Bio-Imaging Techniques is an essential resource for scientists working in the wide range from material sciences, enzymology, analytic, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that also excellent information for teaching is provided.

Biomedical Imaging

Author : Martin Braddock
Publisher : Royal Society of Chemistry
ISBN 13 : 1849730148
Total Pages : 553 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Biomedical Imaging by : Martin Braddock

Download or read book Biomedical Imaging written by Martin Braddock and published by Royal Society of Chemistry. This book was released on 2012 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: The focus of this new book is for medicinal chemists on the chemical agents that have been used, or might be required in the future, and the methods of synthesis for inserting the reporter groups. Medicinal chemists need to know the critical issues involved in using such chemical agents with regard to the biological applications - for instance - what properties are needed chemically and why? The topics covered in the book are: PET, SPECT, contrast agents, radioimaging/radionuclide conjugates, receptor mapping, small animal imaging (eg. WBAR - whole body autoradiography); photoinduced labelling, as well as chapters on the physical techniques used including: NMR, mass spectrometry and Xray. A key reference for academics, postgraduates, researchers, industrialists and professionals working in or joining this field.