Biochemistry Of Copper

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Biochemistry of Copper

Author : Maria C. Linder
Publisher : Springer Science & Business Media
ISBN 13 : 1475794320
Total Pages : 534 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Biochemistry of Copper by : Maria C. Linder

Download or read book Biochemistry of Copper written by Maria C. Linder and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Copper has long been known as essential to living systems, in part through its fundamental role in electron transport and respiration. Over the years into the present, its involvement in an ever increasing number of processes in all kinds of organisms has become apparent, and new and exciting vistas of its roles in such areas as the central nervous system, and in humoral functions, are appearing on the horizon. Although the biochemistry of this element has not been studied nearly as much as that of many others, a for midable amount of work has been carried out. It has thus been a challenge to produce a summary of what has been found that provides both breadth and depth. My goal has been to try to be as comprehensive as possible, within some limitations. I have tried to provide basic information and basic data that should continue to be useful for a long time. The goal has also been to interpret where we currently stand in our knowledge of the structure, function, regulation, and metabolism of Cu-dependent processes and sub stances, especially proteins. Thus, I have tried to make this a source book for historic as well as current information on all aspects of copper bio chemistry, and a summary of our current knowledge of copper-dependent proteins and processes. Most of the research on copper has been carried out on vertebrates, especially mammals. This has played a role in the organization of the book.

Copper in Drinking Water

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309172209
Total Pages : 161 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Copper in Drinking Water by : National Research Council

Download or read book Copper in Drinking Water written by National Research Council and published by National Academies Press. This book was released on 2000-04-12 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: The safety of the nation's drinking water must be maintained to ensure the health of the public. The U.S. Environmental Protection Agency (EPA) is responsible for regulating the levels of substances in the drinking water supply. Copper can leach into drinking water from the pipes in the distribution system, and the allowable levels are regulated by the EPA. The regulation of copper, however, is complicated by the fact that it is both necessary to the normal functioning of the body and toxic to the body at too high a level. The National Research Council was requested to form a committee to review the scientific validity of the EPA's maximum contaminant level goal for copper in drinking water. Copper in Drinking Water outlines the findings of the committee's review. The book provides a review of the toxicity of copper as well as a discussion of the essential nature of this metal. The risks posed by both short-term and long-term exposure to copper are characterized, and the implications for public health are discussed. This book is a valuable reference for individuals involved in the regulation of water supplies and individuals interested in issues surrounding this metal.

Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc

Download Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc PDF Online Free

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 9780309072793
Total Pages : 804 pages
Book Rating : 4.0/5 (727 download)

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Book Synopsis Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc by : Institute of Medicine

Download or read book Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc written by Institute of Medicine and published by National Academies Press. This book was released on 2002-07-19 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the newest release in the authoritative series issued by the National Academy of Sciences on dietary reference intakes (DRIs). This series provides recommended intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for individuals based on age and gender. In addition, a new reference intake, the Tolerable Upper Intake Level (UL), has also been established to assist an individual in knowing how much is "too much" of a nutrient. Based on the Institute of Medicine's review of the scientific literature regarding dietary micronutrients, recommendations have been formulated regarding vitamins A and K, iron, iodine, chromium, copper, manganese, molybdenum, zinc, and other potentially beneficial trace elements such as boron to determine the roles, if any, they play in health. The book also: Reviews selected components of food that may influence the bioavailability of these compounds. Develops estimates of dietary intake of these compounds that are compatible with good nutrition throughout the life span and that may decrease risk of chronic disease where data indicate they play a role. Determines Tolerable Upper Intake levels for each nutrient reviewed where adequate scientific data are available in specific population subgroups. Identifies research needed to improve knowledge of the role of these micronutrients in human health. This book will be important to professionals in nutrition research and education.

Bioinorganic Chemistry of Copper

Author : K.D. Karlin
Publisher : Springer Science & Business Media
ISBN 13 : 940116875X
Total Pages : 510 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Bioinorganic Chemistry of Copper by : K.D. Karlin

Download or read book Bioinorganic Chemistry of Copper written by K.D. Karlin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinorganic Chemistry of Copper focuses on the vital role of copper ions in biology, especially as an essential metalloenzyme cofactor. The book is highly interdisciplinary in its approach--the outstanding list of contributors includes coordination chemists, biochemists, biophysicists, and molecular biologists. Chapters are grouped into major areas of research interest in inorganic copper chemistry, spectroscopy, oxygen chemistry, biochemistry, and molecular biology. The book also discusses basic research of great potential importance to pharmaceutical scientists. This book is based on the first Johns Hopkins University Copper Symposium, held in August 1992. Researchers in chemistry, biochemistry, molecular biology, and medicinal chemistry will find it to be an essential reference on its subject.

Conference on Hemoglobin, 2-3 May 1957

Author : National Research The Division of Medical Sciences the National Heart Institute National Institutes of Health
Publisher : National Academies
ISBN 13 :
Total Pages : 338 pages
Book Rating : 4.1/5 (324 download)

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Book Synopsis Conference on Hemoglobin, 2-3 May 1957 by : National Research The Division of Medical Sciences the National Heart Institute National Institutes of Health

Download or read book Conference on Hemoglobin, 2-3 May 1957 written by National Research The Division of Medical Sciences the National Heart Institute National Institutes of Health and published by National Academies. This book was released on 1958 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biochemistry of the Essential Ultratrace Elements

Author : Earl Frieden
Publisher : Springer Science & Business Media
ISBN 13 : 1468447750
Total Pages : 433 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Biochemistry of the Essential Ultratrace Elements by : Earl Frieden

Download or read book Biochemistry of the Essential Ultratrace Elements written by Earl Frieden and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: The remarkable development of molecular biology has had its counterpart in an impressive growth of a segment of biology that might be described as atomic biology. The past several decades have witnessed an explosive growth in our knowledge of the many elements that are essential for life and maintenance of plants and animals. These essential elements include the bulk elements (hydro gen, carbon, nitrogen, oxygen, and sulfur), the macrominerals (sodium, potas sium, calcium, magnesium, chloride, and phosphorus), and the trace elements. This last group includes the ultra trace elements and iron, zinc, and copper. Only the ultratrace elements are featured in this book. Iron has attracted so much research that two volumes are devoted to this metal-The Biochemistry of Non-Heme Iron by A. Bezkoravainy, Plenum Press, 1980, and The Biochemistry of Heme Iron (in preparation). Copper and zinc are also represented by a separate volume in this series. The present volume begins with a discussion of essentiality as applied to the elements and a survey of the entire spectrum of possible required elements.

Trace Elements and Minerals in Health and Longevity

Author : Marco Malavolta
Publisher : Springer
ISBN 13 : 3030037428
Total Pages : 332 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Trace Elements and Minerals in Health and Longevity by : Marco Malavolta

Download or read book Trace Elements and Minerals in Health and Longevity written by Marco Malavolta and published by Springer. This book was released on 2018-11-13 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the role of trace elements in health and longevity, pursuing a biogerontological approach. It offers essential information on the impact of trace elements on molecular and physiological processes of aging, and on their impact on health in connection with aging. The major topics covered in its 11 chapters, each dedicated to a specific trace element or mineral, are: a) Role of the element in species longevity, b) Recommended intake for longevity in animal species and in the elderly, c) Deficiency and age-related disease, d) Excess/toxicity and age-related disease, and e) Interactions with drugs prescribed in the elderly. Clinical, animal and other laboratory models of interest in aging are included, which enable a more in-depth analysis to be made. The respective chapters are a mixture of overviews and more in-depth reviews in which the mechanisms of aging are described from the point of view of their specific interactions with trace elements and minerals.

Diet and Health

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309039940
Total Pages : 765 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Diet and Health by : National Research Council

Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.

Handbook of Copper Pharmacology and Toxicology

Author : Edward J. Massaro
Publisher : Springer Science & Business Media
ISBN 13 : 1592592880
Total Pages : 600 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Handbook of Copper Pharmacology and Toxicology by : Edward J. Massaro

Download or read book Handbook of Copper Pharmacology and Toxicology written by Edward J. Massaro and published by Springer Science & Business Media. This book was released on 2002-07-01 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edward J. Massaro and a panel of leading biomedical researchers and clinical practitioners review, in-depth, the status of our current knowledge concerning the biochemistry of copper in general and its role in health and disease in particular. Drawing on the wealth of new information emerging from the molecular biology revolution, these experts survey the most important research areas of copper pharmacology and toxicology, including copper proteins and transport, copper toxicity and therapeutics, and copper metabolism and homeostasis. They also discuss the molecular pathogenesis of copper in a variety of metabolic diseases, Menkes and Wilson's diseases and occipital horn syndrome, as well as the role of copper in Parkinson's disease, prion disease, familial amytrophic lateral sclerosis (ALS), and Alzheimer's disease.

The Prion Protein

Author : Jorg Tatzelt
Publisher :
ISBN 13 : 9780954333522
Total Pages : 80 pages
Book Rating : 4.3/5 (335 download)

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Book Synopsis The Prion Protein by : Jorg Tatzelt

Download or read book The Prion Protein written by Jorg Tatzelt and published by . This book was released on 2010 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: A conformational transition of the cellular prion protein (PrPC) into an aberrantly folded isoform designated scrapie prion protein (PrPSc) is the hallmark of a variety of neurodegenerative disorders collectively called prion diseases. They include Creutzfeldt-Jakob disease and Gerstmann-Stäussler-Scheinker syndrome in humans, scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle and chronic wasting disease (CWD) in free-ranging deer. In contrast to the deadly properties of misfolded PrP, PrPC seems to possess a neuroprotective activity. More-over, animal models indicated that the stress-protective activity of PrPC and the neurotoxic effects of PrPSc are somehow interconnected. In this timely book, leading scientists in the field have come together to highlight the apparently incongruous activities of different PrP conformers. The articles outline current research on celluar pathways implicated in the formation and signaling of neurotoxic and physiological PrP isoforms and delineate future research direction. Topics covered include the physiologcial activity of PrPC and its possible role as a neurotrophic factor, the finding that aberrant PrP conformers can cause neurodegeneration in the absence of infectious prion propagation, the requirement of the GPI anchor of PrPC for the neurotoxic effects of scrapie prions, the pathways implicated in the formation and neurotoxic properties of cytosolically localized PrP, the impact of metal ions on the processing of PrP, and the role of autophagy in the propagation and clearance of PrPSc. The book is fully illustrated and chapters include comprehensive reference sections. Essential reading for scientists involved in prion research.

Mitochondrial Function

Author : William S. Allison
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (639 download)

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Book Synopsis Mitochondrial Function by : William S. Allison

Download or read book Mitochondrial Function written by William S. Allison and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Tietz Fundamentals of Clinical Chemistry Passcode Only

Author : Carl A. Burtis
Publisher : W B Saunders Company
ISBN 13 : 9781455734405
Total Pages : 976 pages
Book Rating : 4.7/5 (344 download)

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Book Synopsis Tietz Fundamentals of Clinical Chemistry Passcode Only by : Carl A. Burtis

Download or read book Tietz Fundamentals of Clinical Chemistry Passcode Only written by Carl A. Burtis and published by W B Saunders Company. This book was released on 2007-11-06 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a Pageburst digital textbook; the product description may vary from the print textbook. A condensed, student-friendly version of Tietz Textbook of Clinical Chemistry, this text uses a laboratory perspective to provide you with the chemistry fundamentals you need to work in a real-world, clinical lab. Accurate chemical structures are included to explain the key chemical features of relevant molecules. Offering complete, accurate coverage of key topics in the field, it's everything that you expect from the Tietz name! More than 500 illustrations and easy-to-read tables help you understand and remember key concepts. Key words, learning objectives, and other student-friendly features reinforce important material. Chapter review questions are included in an appendix to test your knowledge. A two-color design makes it easier to read and easy to find important topics. In-depth, reader-friendly content is appropriate for MT/CLS and MLT/CLT students and may also be used by laboratory practitioners, pathology residents, and others. A new chapter on newborn screening discusses the basic principles, screening recommendations, inborn errors, methods, and interpretation of results. A comprehensive glossary provides easy-to-find definitions of key terms. An Evolve website provides regular updates of content, answers to review questions, and web links to related sites for further research and study.

Nutrition and Lifestyle for Pregnancy and Breastfeeding

Author : Peter D. Gluckman
Publisher :
ISBN 13 : 0198722702
Total Pages : 449 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Nutrition and Lifestyle for Pregnancy and Breastfeeding by : Peter D. Gluckman

Download or read book Nutrition and Lifestyle for Pregnancy and Breastfeeding written by Peter D. Gluckman and published by . This book was released on 2015 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explaining the practical implications of new discoveries in 'life-course biology', Nutrition and Lifestyle for Pregnancy and Breastfeeding is an informed resource on factors that affect offspring development. The impact of parental lifestyle and behavioural choices influence not only fetal development and birth outcomes, but also postnatal development, yet guidance on appropriate diet, behaviour, and exposures during pregnancy is often confusing and contradictory. With accessible explanations of the latest scientific research, and clear summaries and recommendations, this book is a valuable and authoritative guide for all levels of health care providers. The authors provide an overview of the background evidence, highlighting the importance of lifestyle choices prior to and during pregnancy. In-depth discussions of nutritional and lifestyle factors that impact on pregnancy and offspring outcomes are based on the latest research and exploration of key scientific studies. Nutrition and Lifestyle for Pregnancy and Breastfeeding is a manual offering both scientific and clinical evidence to empower health care providers and ensure they have the information necessary to confidently care for prospective and new parents.

Biological Inorganic Chemistry

Author : Robert R. Crichton
Publisher : Elsevier
ISBN 13 : 0080556221
Total Pages : 383 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Biological Inorganic Chemistry by : Robert R. Crichton

Download or read book Biological Inorganic Chemistry written by Robert R. Crichton and published by Elsevier. This book was released on 2007-12-11 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment.Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on.Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject.Many colour illustrations. Enables easier visualization of molecular mechanismsWritten by a single author. Ensures homgeneity of style and effective cross referencing between chapters

Antioxidant Nutrients and Immune Functions

Author : Adrianne Bendich
Publisher : Springer Science & Business Media
ISBN 13 : 1461305535
Total Pages : 173 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Antioxidant Nutrients and Immune Functions by : Adrianne Bendich

Download or read book Antioxidant Nutrients and Immune Functions written by Adrianne Bendich and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: The detenmnation of optimal nutritional status has traditionally been based upon generalized parameters such as weight gain and body fat levels. Vitamin and mineral requirements were often related to the intakes needed to prevent overt signs of deficiency diseases such as beriberi or scurvy. However, in the past decade or so, there have been intensive investigations to determine the subtle changes in physiological functions associated with marginal micronutrient intakes. There is a growing consensus that immune system activities are very sensitive indicators of micronutrient status. During this decade, there has also been a rapid expansion of research in the role of free radicals and antioxidants in the major chronic diseases which afflict mankind( i.e. cancer, cardiovascular disease,and autoimmune disease). The main function of antioxidant nutrients in an appropriate diet is the prevention of oxidative damage to cells and their physiological functions. Antioxidant nutrients counteract free radicals and damaging oxidative actions on cell membranes. Since the cells of the immune system are rapidly differentiating and proliferating, such dividing and transforming cells are particularly susceptible to damage by oxidation. The interactions of antioxidant nutrition and immune system activities and disease resistance are therefore logical areas for research. Thus, the objective of this symposium was to bring together the leading investigators who have examined the immunological effects of dietary essential nutrients which share the capacity to act as antioxidants.

Encyclopedia of Metalloproteins

Author : Robert H. Kretsinger
Publisher : Springer
ISBN 13 : 9781461415329
Total Pages : 0 pages
Book Rating : 4.4/5 (153 download)

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Book Synopsis Encyclopedia of Metalloproteins by : Robert H. Kretsinger

Download or read book Encyclopedia of Metalloproteins written by Robert H. Kretsinger and published by Springer. This book was released on 2013-05-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In biochemistry, a metalloprotein is a generic term for a protein that contains a metal cofactor. The metal may be an isolated ion or may be coordinated with a nonprotein organic compound, such as the porphyrin found in hemoproteins. In some cases, the metal is co-coordinated with a side chain of the protein and an inorganic nonmetallic ion. This kind of protein-metal-nonmetal structure is seen in iron-sulfur clusters Metalloproteins deals with all aspects related to the intracellular and extracellular metal-binding proteins, including their structures, properties and functions. The biological roles of metal cations and metal-binding proteins are endless. They are involved in all crucial cellular activities. Many pathological conditions are related to the problematic metal metabolism. Research in metalloprotein-related topics is therefore rapidly growing, and different aspects of metal-binding proteins progressively enter curricula at Universities and even at the High School level on occasion. However, no key resource providing basic, but comprehensible knowledge on this rapidly expanding field exists. The Encyclopedia of Metalloproteins aims to bridge this gap, and will attempt to cover various aspects of metalloprotein/metalloproteomics and will deal with the different issues related to the intracellular and extracellular metal-binding proteins, including their structures, properties and functions. The goal is to cover exhaustively all catalytically and biologically crucial metal ions and to find at least one interacting protein for other metal ions. The Encyclopedia of Metalloproteins will provide a key resource for advanced undergraduate and graduate students, researchers, instructors, and professors interested in protein science, biochemistry, cell biology, and genetics.

Vitamin C

Author : M B Davies
Publisher : Royal Society of Chemistry
ISBN 13 : 1847552307
Total Pages : 174 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Vitamin C by : M B Davies

Download or read book Vitamin C written by M B Davies and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamin C is the first book to cover the history, chemistry, biochemistry, and medical importance of vitamin C and is the first to provide an in-depth, interdisciplinary study of this essential and fascinating compound. The book provides a comprehensive and systematic account of the vitamin C story, fully surveying the history of scurvy and how its cure led to the suggestion, discovery, and isolation of the vitamin, later named L-ascorbic acid. It describes in detail the vitamin's structure determination, synthesis and manufacture, and its oxidation products, derivatives and related compounds. Its key biochemical roles are fully categorized and explained, and the medical importance of the vitamin, including the recent use of so-called megadoses, is thoroughly discussed. Vitamin C will be of interest to a very wide readership and will provide useful background information and inspiration for students at various levels. It will also be relevant to the interested chemist or lay person, as well as those carrying out research in this area.