Biochemical Characterization of Lymphokines

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Publisher :
ISBN 13 :
Total Pages : 664 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Biochemical Characterization of Lymphokines by : Alain L. de Weck

Download or read book Biochemical Characterization of Lymphokines written by Alain L. de Weck and published by . This book was released on 1980 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Lymphokines

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Publisher :
ISBN 13 :
Total Pages : 472 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Lymphokines by : John W. Hadden

Download or read book The Lymphokines written by John W. Hadden and published by . This book was released on 1981-10-31 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Human Lymphokines

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Publisher : Elsevier
ISBN 13 : 0323142672
Total Pages : 756 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Human Lymphokines by : Amanullah Khan

Download or read book Human Lymphokines written by Amanullah Khan and published by Elsevier. This book was released on 2012-12-02 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Lymphokines: The Biological Immune Response Modifiers is a collection of papers presented at the Third International Symposium on Human Lymphokines held on October 15-17, 1981 at the Wadley Institutes of Molecular Medicine in Dallas, Texas. Contributors explore the role of human lymphokines in immune responses and their applications in immunotherapy. The focus is on lymphokines that have either entered clinical trials or are nearing clinical evaluation. Some of the activities of possible immediate significance, such as Glia cell stimulating factor and polyclonal B-cell activator, are also described. This volume is organized into six sections encompassing 56 chapters and begins with an overview of assay systems, touching on topics such as the activation of macrophages by interferon to produce plasminogen and macrophage activation by lymphokine factors. The next sections turn to the production, purification, and biological and chemical characterization of lymphokines. The discussion then shifts to the mechanisms of action of lymphokines in vitro and the use of animal models in lymphokine investigations, including lymphokine fractions in a mouse tumor model and enhancement of natural killing activity by different types of interferon. A great deal of emphasis is placed on macrophage migration inhibitory factor, lymphotoxins, gamma interferon, and interleukins. The book concludes with chapters devoted to the immunoregulatory effects of lymphokines and clinical studies.

Lymphokines

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Publisher : Elsevier
ISBN 13 : 1483266990
Total Pages : 472 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Lymphokines by : Edgar Pick

Download or read book Lymphokines written by Edgar Pick and published by Elsevier. This book was released on 2014-06-05 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lymphokines: A Forum for Immunoregulatory Cell Products deals with immunoregulatory cell products that produce lymphokines. Topics covered include the purification and characterization of transfer factor; activation of cytotoxicity and/or suppressor activity in murine macrophages by lymphokines, lipopolysaccharide, and polyinosinic-polycytidylic acid; and the role of clotting processes in the action of lymphokines on macrophages. A comparison of the immune-modulating effects of interferon and interferon inducers is also presented. Comprised of 13 chapters, this volume begins with a discussion on transfer factor and its ability to react specifically with antigens. The clinical uses of transfer factor are considered with special emphasis on its value as a prophylactic agent. The reader is then introduced to the subject of T cell regulation of the immunoglobulin E (IgE) response via potentiating and suppressor lymphokines, together with the possible clinical application of IgE suppressive factors in the treatment of atopic diseases. Subsequent chapters examine the evidence in favor of the existence of T cell-derived polyclonal B cell activator (PBA) playing a role in both normal antibody responses and autoimmune diseases; the role of suppressor T cells and the associated lymphokines in contact sensitivity in mice; and lymphokine action on macrophages. The book also analyzes the genetics of the response of human and mouse cells to interferons. This monograph will be helpful to practitioners and researchers in the fields of microbiology and immunology.

Mediators of the Immune Response

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Publisher : Routledge
ISBN 13 :
Total Pages : 348 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Mediators of the Immune Response by : Nikolaĭ Vasilʹevich Medunitsyn

Download or read book Mediators of the Immune Response written by Nikolaĭ Vasilʹevich Medunitsyn and published by Routledge. This book was released on 1987 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Thymic Hormones and Lymphokines

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Publisher : Springer
ISBN 13 :
Total Pages : 738 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Thymic Hormones and Lymphokines by : Allan Goldstein

Download or read book Thymic Hormones and Lymphokines written by Allan Goldstein and published by Springer. This book was released on 1984-11 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Third Annual Symposium on Health Sciences attracted over 400 scientists from 15 countries. It was held at the National Academy of Sciences in Washington, D.C. The theme of this meeting was "Thymic Hormones and Lymphokines: Basic Chem istry and Clinical Applications." The meeting emphasized the state of the art with regard to chemistry, mech anism of action, and clinical applications of thymic hormones and lymphokines. In addition to the five sessions, the chairmen of each session were asked to prepare a synthesis and overview of each of the sessions. Some of the chairmen used this time to summarize the new material presented while others addressed important areas of conflict and terminology. The chairmen of the plenary sessions prepared short summary papers which have been incorporated into this volume at the end of each major section. We also invited several of the scientists who took part in the poster presentations to submit short papers. In addition to the scientific sessions, there were two awards and lectures. One, the Abraham White Distinguished Science Award, was given to Dr. Robert C. Gallo, who gave the keynote lecture. He was recognized for his pioneering research and scientific contributions to our understanding of the regulation of hematopoietic cell differentiation and the role of viruses in the development of human leukemias.

Biology of the Lymphokines

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Publisher : Academic Press
ISBN 13 : 1483271420
Total Pages : 645 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Biology of the Lymphokines by : Stanley Cohen

Download or read book Biology of the Lymphokines written by Stanley Cohen and published by Academic Press. This book was released on 2013-09-17 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology of the Lymphokines discusses the scope and diversity of lymphokine research. This book focuses on the studies on lymphokines, such as those involving cellular source, chemical nature, purification strategies, and bioassay limitations. The mechanism of lymphokine action, lymphokines in vivo, and value of lymphokine quantitations are also covered. This text describes the repertoire of lymphokines produced by various lymphoblastoid cell lines and its significance for coping with the problem of large scale lymphokine production. The anti-viral and general immunoregulatory properties of interferons and rationale developed for integrating interferons with the family of lymphokines are likewise deliberated. This publication is a good source for students and researchers conducting work on lymphokines.

Isolation Characterization, and Utilization of T Lymphocyte Clones

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Publisher : Elsevier
ISBN 13 : 032314537X
Total Pages : 581 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Isolation Characterization, and Utilization of T Lymphocyte Clones by : C Fathman

Download or read book Isolation Characterization, and Utilization of T Lymphocyte Clones written by C Fathman and published by Elsevier. This book was released on 2012-12-02 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: Isolation, Characterization, and Utilization of T Lymphocyte Clones is a summary of information regarding T lymphocyte clones, including their usefulness. Organized into nine parts, the book begins with discussions on the soluble factors that can influence the growth of cloned T cells and the utilization of T cell hybridomas for analysis of T cell functions, emphasizing the biochemical and functional properties of helper and suppressor factors. The book then looks into the analysis of T cell clones and hybridomas using techniques of somatic cell genetics. The clonal analysis by limiting dilution, the characteristics of murine T cell clones reactive with alloantigens and soluble antigens, and the human T cell clones are described as well. This volume is valuable to those interested in the field of cloning of immunocompetent T cells.

The Pharmacology of Lymphocytes

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Publisher : Springer Science & Business Media
ISBN 13 : 3642732178
Total Pages : 633 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis The Pharmacology of Lymphocytes by : Michael A. Bray

Download or read book The Pharmacology of Lymphocytes written by Michael A. Bray and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Immunopharmacology" , why not "pharmacoimmunology"? Professor H. O. Schild University College London, 1962 An intact immune response is essential for survival, as is evidenced by the various innate immune deficiency syndromes and by the emergence of the acquired immune deficiency syndrome (AIDS) as a pandemic during the last decade. Substances which stimulate the immune response might contribute to the therapy of AIDS and its precursor, AIDS-related syndrome, as well as of other clinical conditions in which immune responses can be diminished, such as carcinoma and infections. In other circumstances, an intact or heightened immune response may pose clinical problems; hence there is need to suppress, or diminish, components of the immune response. For instance, it is necessary to impair cellular immunity in order to ensure lasting acceptance of heterografts and it is already established that agents effective in transplantation are therapeutically effective in an range of autoimmune diseases. More recently, experimental studies have indicated that aberrant manifestations of humoral immunity, as in allergies, may also be amenable to pharmacological intervention.

The Reticuloendothelial System

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Publisher : Springer Science & Business Media
ISBN 13 : 1468451588
Total Pages : 502 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis The Reticuloendothelial System by : S.M. Phillips

Download or read book The Reticuloendothelial System written by S.M. Phillips and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from those cells which constitute the RES. It may now be more fashionable in some quarters to consider these cells as part of what is called the mononuclear phagocytic system or the lymphoreticular sys tem. Nevertheless, because of historical developments and current interest in the subject by investigators from many diverse areas, it seems advantageous to present in one comprehensive treatise current information and knowledge con cerning basic aspects of the RES, such as morphology, biochemistry, phylogeny and ontogeny, physiology, and pharmacology as well as clinical areas including immunopathology, cancer, infectious diseases, allergy, and hypersensitivity. It is anticipated that, by presenting information concerning these apparently het erogeneous topics under the unifying umbrella of the RES, attention will be focused on the similarities as well as interactions among the cell types constitut ing the RES from the viewpoint of various disciplines. The treatise editors and their editorial board, consisting predominantly of the editors of individual vol and enormous task umes, are extremely grateful for the enthusiastic cooperation undertaken by members of the biomedical community in general and especially and Japanese Reticuloen by members of the American as well as European dothelial Societies.

Biological Response Modifiers

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Publisher : Elsevier
ISBN 13 : 0323151388
Total Pages : 416 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Biological Response Modifiers by : Paul Torrence

Download or read book Biological Response Modifiers written by Paul Torrence and published by Elsevier. This book was released on 2012-12-02 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Response Modifiers: New Approaches to Disease Intervention focuses on biological response modifiers (BRMs) and the ways they provide novel approaches to disease control. It examines how BRMs act through an organism's own biological response mechanisms and how their mechanisms of action can be utilized to develop new modalities of chemotherapy. Organized into 15 chapters, this volume begins with an overview of specific agents and approaches to biological therapy, the basic concepts of immunity, and BRM screening. It then discusses interferons and their immunoregulatory functions; mechanism of interferon action; how nucleic acids and polynucleotides regulate the immune system; clinical applications of thymosins and other thymic hormones; the antibacterial and antineoplastic properties of tuftsin; and production and characterization of tumor necrosis factor. The reader is also introduced to detection and activity of colony-stimulating factor; the role of neuroendocrine hormones in the immune system; chalones and other endogenous inhibitors of cell proliferation; biochemistry of lymphotoxins; muramyl peptides as immunopharmacological response modifiers; biological activities of transfer factor in leukocyte dialysates; and requirements for activation and growth of human lymphocytes. This book is a valuable resource for immunologists, clinicians, biochemists, and organic/medicinal chemists.

Pituitary Function and Immunity

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Publisher : CRC Press
ISBN 13 : 1000013316
Total Pages : 346 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Pituitary Function and Immunity by : Istvan Berczi

Download or read book Pituitary Function and Immunity written by Istvan Berczi and published by CRC Press. This book was released on 2019-06-04 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1986, the influence of hormones secreted or regulated by the pituitary gland on the immune system is examined in detail, including discussions of adrenocorticotropic hormone, glucocorticoids, catecholamines, growth hormone, insulin, prolactin, gonadotropins, sex steroid hormones, and thyroid hormones. The relative importance of various hormones in immunoregulation is considered, and evidence for interaction between the immune and neurohormonal systems is presented. The possible effects of hormonal immunomodulation in reproduction, infections and parasitic disease, autoimmu-nity, and cancer are examined. This comprehensive reference serves both basic and clinical researchers and practitioners in immunology, microbiology, endocrinology, reproduction biology, neurology, oncology, psychology, medicine, and veterinary medicine.

T Cell Hybridomas

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Publisher : Springer Science & Business Media
ISBN 13 : 3642685862
Total Pages : 260 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis T Cell Hybridomas by : H.v. Boehmer

Download or read book T Cell Hybridomas written by H.v. Boehmer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: For more than ten years cell fusion techniques have been applied in studies on various lymphocyte functions. Ig expression was first studied in hybrids obtained by fusing myeloma cells with fibroblasts (1) or lymphomas (2), both of which do not produce Ig, and with Ig producing myelomas (3) or human blood lymphocytes (4). Kohler and Milstein (5) fused a myeloma with spleen cells from immunized mice. Up to 10% of the hybrids obtained secreted antibodies specific for the immunizing antigen. This suggested that plasma cells preferenti ally fused with the myeloma cells, a finding which was of enormous practical value. It was found that both Band T lymphocytes could be fused with the T cell tumor BW5147, which is however not permissive for Ig synthesis (6). A very large number of T cell hybridomas were generated by fusing BW5147 with cell populations containing in vivo or in vitro activated cells (7). The hybrids showed no specific T cell functions and binding assays for T cell receptors were not available. In particular, no hybrids were obtained which expreS1ed specific cytolytic activity that could be tested in short-term Cr release assays (8). However, the frustrations expressed about these failures, published in January, 1978 (9), were relieved by Taniguchi and Miller's publication a few months later of T cell hybridomas producing antigen-specific suppressor factors (10). Unfortunately, their hybrids rapidly lost factor production.

Immunology

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Publisher : Springer Science & Business Media
ISBN 13 : 1475767846
Total Pages : 361 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Immunology by : Joseph Bellanti

Download or read book Immunology written by Joseph Bellanti and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio medical scientists in general who are interested in the intricate system of ceHs and molecular moieties derived from those ceHs which constitute the RES. It may now be more fashionable in some quarters to consider these ceHs as part of what is caHed the mononuclear phagocytic system or the lymphoreticular system. Nev ertheless, because of historical developments and current interest in the subject by investigators from many diverse areas, it seems advantageous to present in one comprehensive treatise current information and knowledge concerning basic aspects of the RES, such as morphology, biochemistry, phylogeny and ontogeny, physiology, and pharmacology as weIl as clinical areas including immu nopathology, cancer, infectious diseases, allergy, and hypersensitivity. It is antic ipated that by presenting information concerning these apparently hetero geneous topics under the unifying umbreHa of the RES attention will be focused on the similarities as weIl as interactions among the ceH types constituting the RES from the viewpoint of various disciplines. The treatise editors and their editorial board, consisting predominantly of the editors of individual volumes, are extremely grateful for the enthusiastic cooperation and enormous task under taken by members of the biomedical community in general and especially by members of the American as weIl as European and Japanese Reticuloendotheli~l Societies.

Biological Response Modifiers

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Publisher :
ISBN 13 :
Total Pages : 272 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Biological Response Modifiers by :

Download or read book Biological Response Modifiers written by and published by . This book was released on 1983 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Natural Cell-Mediated Immunity Against Tumors

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Publisher : Elsevier
ISBN 13 : 0323141730
Total Pages : 1345 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Natural Cell-Mediated Immunity Against Tumors by : Ronald Herberman

Download or read book Natural Cell-Mediated Immunity Against Tumors written by Ronald Herberman and published by Elsevier. This book was released on 2012-12-02 with total page 1345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Cell-Mediated Immunity Against Tumors aims to be the first book to provide a comprehensive discussion on natural cell-mediated immunity against tumors. This book is mostly a collection of different research contributed by leading laboratories. It also presents a better perspective of how natural mechanisms fit in with and relate to the traditional and more extensively studied components of the immune system. The book starts off with an overview of the contents of the volume – the historical development of the advances in the field of research and the status of knowledge in the subject area. Divided into four major sections, the book consists of a total of 98 chapters. The sections discuss the natural killer cells and related cells and the natural lymphokine production. This book also explains the natural macrophage and granulocyte cytotoxicity. The book will be a helpful reference for students, professionals, and researchers in biology, immunology, biochemistry, microbiology, and other related fields.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1428 pages
Book Rating : 4.3/5 (243 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1990 with total page 1428 pages. Available in PDF, EPUB and Kindle. Book excerpt: