Bioactive Secondary Metabolites From Marine Algae And Study Of Oxidized Anandamide Derivatives

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Bioactive Secondary Metabolites from Marine Algae and Study of Oxidized Anandamide Derivatives

Author : Hye-Dong Yoo
Publisher :
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.:/5 (391 download)

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Book Synopsis Bioactive Secondary Metabolites from Marine Algae and Study of Oxidized Anandamide Derivatives by : Hye-Dong Yoo

Download or read book Bioactive Secondary Metabolites from Marine Algae and Study of Oxidized Anandamide Derivatives written by Hye-Dong Yoo and published by . This book was released on 1997 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: My investigations of the natural products of marine algae have resulted in the discovery of several new secondary metabolites. Bioassay-guided fractionation led to the isolation of these new compounds and spectroscopic analysis was utilized in their structural characterization. Two new and potent antimitotic metabolites, curacins B and C, were isolated from a Curacao collection of Lyngbya majuscula. In addition, four curacin A analogs were prepared by semisynthetic methods. The structures of the new curacins and the curacin A analogs were determined by spectroscopic analysis in comparison with curacin A. The biological properties of the new natural products and synthetic derivatives of curacin A were examined. Investigations of another Curacao collection of L. majuscula revealed a new cytotoxic lipopeptide, microcolin C. Microcolin C was found to have an interesting profile of cytotoxicity to human cancer-derived cell lines. A new metabolite, vidalenolone, was isolated from an Indonesian red alga Vidalia sp. The structure of this new cyclopentenolone-containing compound was determined by a combination of spectroscopic methods. Filamentous cells isolated from female gametophytes of the brown alga Laminaria saccharina were cultured in flasks or bioreactors. These cultures produced a variety of w6-lipoxygenase metabolites: 13-hydroxy-9,11-octadecadienoic acid (13-HODE), 13-hydroxy-6,9,11,15-octadecatetraenoic acid (13-HODTA), and 15-hydroxy-5,8,11,13-eicosatetraenoic acid (15-HETE). Five oxidized anandamide derivatives were prepared from anandamide through autoxidation in an exploration of ligand binding to the cannabinoid receptor. Their structures were determined by a combination of NMR spectroscopy and GC-MS. The cannabinoid receptor binding affinity of these derivatives was evaluated. This study revealed the following trend in activity: anandamide> 15-> 9-> 8-> 11-> 5-hydroxyanandamide.

Medicinal Natural Products

Author : Paul M. Dewick
Publisher : John Wiley & Sons
ISBN 13 : 9780471496410
Total Pages : 524 pages
Book Rating : 4.4/5 (964 download)

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Book Synopsis Medicinal Natural Products by : Paul M. Dewick

Download or read book Medicinal Natural Products written by Paul M. Dewick and published by John Wiley & Sons. This book was released on 2002-01-03 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals. Structured according to biosynthetic pathway, it is written from a chemistry-based approach.

Handbook of Algal Science, Technology and Medicine

Author : Ozcan Konur
Publisher : Academic Press
ISBN 13 : 0128183063
Total Pages : 738 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Handbook of Algal Science, Technology and Medicine by : Ozcan Konur

Download or read book Handbook of Algal Science, Technology and Medicine written by Ozcan Konur and published by Academic Press. This book was released on 2020-03-28 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Algal Science, Microbiology, Technology and Medicine provides a concise introduction to the science, biology, technology and medical use of algae that is structured on the major research fronts of the last four decades, such as algal structures and properties, algal biomedicine, algal genomics, algal toxicology, and algal bioremediation, algal photosystems, algal ecology, algal bioenergy and biofuels. It also covers algal production for biomedicine, algal biomaterials, and algal medicinal foods within these primary sections. All chapters are authored by the leading researchers in their respective research fields. Our society currently faces insurmountable challenges in the areas of biomedicine and energy in the face of increasing global population and diminishing natural resources as well as the growing environmental and economic concerns, such as global warming, greenhouse gas emissions and climate change. Algae offer a way to deal with these challenges and concerns for both sustainable and environment friendly bioenergy production and in biomedicine through the development of crucial biotechnology. Provides an essential interdisciplinary introduction and handbook for all the stakeholders engaged in science, technology and medicine of algae Covers the major research streams of the last four decades, ranging from algal structures, to algal biomedicine and algal bioremediation Fills a significant market opening for an interdisciplinary handbook on algal science, technology and medicine

American Doctoral Dissertations

Author :
Publisher :
ISBN 13 :
Total Pages : 806 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis American Doctoral Dissertations by :

Download or read book American Doctoral Dissertations written by and published by . This book was released on 1997 with total page 806 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Seaweed in Health and Disease Prevention

Author : Joël Fleurence
Publisher : Academic Press
ISBN 13 : 0128027932
Total Pages : 480 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Seaweed in Health and Disease Prevention by : Joël Fleurence

Download or read book Seaweed in Health and Disease Prevention written by Joël Fleurence and published by Academic Press. This book was released on 2016-04-05 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seaweed in Health and Disease Prevention presents the potential usage of seaweed, macroalgae, and their extracts for enhancing health and disease. The book explores the possibilities in a comprehensive way, including outlining how seaweed can be used as a source of macronutrients and micronutrients, as well as nutraceuticals. The commercial value of seaweed for human consumption is increasing year-over-year, and some countries harvest several million tons annually. This text lays out the properties and effects of seaweeds and their use in the food industry, offering a holistic view of the ability of seaweed to impact or effect angiogenesis, tumors, diabetes and glucose control, oxidative stress, fungal infections, inflammation and infection, the gut, and the liver. Combines foundational information and nutritional context, offering a holistic approach to the relationship between sea vegetables, diet, nutrition, and health Provides comprehensive coverage of health benefits, including sea vegetables as sources of nutraceuticals and their specific applications in disease prevention, such as angiogenesis, diabetes, fungal infections, and others Includes Dictionary of Terms, Key Facts, and Summary points in each chapter to enhance comprehension Includes information on toxic varieties and safe consumption guidelines to supplement basic coverage of health benefits

Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharides

Author : Antony Bacic
Publisher : Academic Press
ISBN 13 : 0080920543
Total Pages : 713 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharides by : Antony Bacic

Download or read book Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharides written by Antony Bacic and published by Academic Press. This book was released on 2009-07-07 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry, Biochemistry, and Biology of 1-3 Beta Glucans and Related Polysaccharides presents a comprehensive, systematic and authoritative survey of information about a family of chemically related, but functionally diverse, naturally occurring polysaccharides--the (1-3)-glucans. International contributors describe the chemical and physicochemical properties of these glucans and their derivatives and the molecular biological and structural aspects of the enzymes involved in their formation and breakdown. A detailed analysis of their physiological roles in the various biological situations in which they are found will be provided. Additionally, evolutionary relationships among the family of these glucans will be described. Topics of medical relevance include detailing the glucans' interactions with the immune system and research for cancer therapy applications Web resource links allow scientists to explore additional beta glucan research Separate indexes divided into Species and Subject for enhanced searchability

Marine Cyanobacteria

Author : Loïc Charpy
Publisher : Musee Oceanographique
ISBN 13 :
Total Pages : 644 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Marine Cyanobacteria by : Loïc Charpy

Download or read book Marine Cyanobacteria written by Loïc Charpy and published by Musee Oceanographique. This book was released on 1999 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Voltage Gated Sodium Channels

Author : Peter C. Ruben
Publisher : Springer Science & Business Media
ISBN 13 : 3642415881
Total Pages : 328 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Voltage Gated Sodium Channels by : Peter C. Ruben

Download or read book Voltage Gated Sodium Channels written by Peter C. Ruben and published by Springer Science & Business Media. This book was released on 2014-04-15 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.

Annual Plant Reviews, Functions and Biotechnology of Plant Secondary Metabolites

Author : Michael Wink
Publisher : John Wiley & Sons
ISBN 13 : 1444318888
Total Pages : 424 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Annual Plant Reviews, Functions and Biotechnology of Plant Secondary Metabolites by : Michael Wink

Download or read book Annual Plant Reviews, Functions and Biotechnology of Plant Secondary Metabolites written by Michael Wink and published by John Wiley & Sons. This book was released on 2010-01-26 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important volume commences with an overview of the modes of action of defensive secondary metabolites, followed by detailed surveys of chemical defense in marine ecosystems, the biochemistry of induced defense, plant-microbe interactions and medical applications. A chapter is also included covering biotechnological aspects of producing valuable secondary metabolites in plant cell and organ cultures. This is a comprehensive and fully updated new edition, edited by Professor Michael Wink and including contributions from many internationally acknowledged experts in the field.

Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases

Author : Tahira Farooqui
Publisher : Academic Press
ISBN 13 : 0128119608
Total Pages : 485 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases by : Tahira Farooqui

Download or read book Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases written by Tahira Farooqui and published by Academic Press. This book was released on 2017-10-24 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Role of the Mediterranean Diet in the Brain and Neurodegenerative Disease provides a comprehensive overview of the effects of all components of the Mediterranean diet on the brain, along with its beneficial effects in neurodegenerative diseases. It covers topics on neurodegenerative diseases (Alzheimer disease (AD), Parkinson disease, (PD) Huntington disease (HD) and Amyotrophic Lateral Sclerosis (ALS), also providing information on how cardiovascular disease, Type 2 Diabetes, and Metabolic Syndrome become risk factors for neurodegenerative diseases. This book focuses on how the Mediterranean diet suppresses oxidative stress and neuroinflammation in neurodegenerative diseases as well as signal transduction. The Mediterranean diet is characterized by the abundant consumption of olive oil, high consumption of plant foods (fruits, vegetables, pulses, cereals, nuts and seeds); frequent and moderate intake of wine (mainly with meals); moderate consumption of fish, seafood, yogurt, cheese, poultry and eggs; and low consumption of red meat and processed meat products. High consumption of dietary fiber, low glycemic index and glycemic load, anti-inflammatory effects, and antioxidant compounds may act together to produce favorable effects on health status. Collective evidence suggests that Mediterranean diet not only increases longevity by lowering cardiovascular disease, inhibiting cancer growth, but also by protecting the body from age-dependent cognitive decline. Comprehensively provides an overview of the effects of the Mediterranean diet on the brain and its beneficial effects in neurodegenerative diseases Discusses the relationship among Type 2 Diabetes, Metabolic Syndrome and Alzheimer's Disease, and the effect of the Mediterranean diet on normal aging, longevity, and other neurodegenerative diseases Focuses on how the Mediterranean diet suppresses oxidative stress and neuroinflammation in neurodegenerative disease

Handbook of Cyanobacterial Monitoring and Cyanotoxin Analysis

Author : Jussi Meriluoto
Publisher : John Wiley & Sons
ISBN 13 : 1119068746
Total Pages : 886 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Handbook of Cyanobacterial Monitoring and Cyanotoxin Analysis by : Jussi Meriluoto

Download or read book Handbook of Cyanobacterial Monitoring and Cyanotoxin Analysis written by Jussi Meriluoto and published by John Wiley & Sons. This book was released on 2016-12-08 with total page 886 pages. Available in PDF, EPUB and Kindle. Book excerpt: A valuable handbook containing reviews, practical methods and standard operating procedures. A valuable and practical working handbook containing introductory and specialist content that tackles a major and growing field of environmental, microbiological and ecotoxicological monitoring and analysis Includes introductory reviews, practical analytical chapters and a comprehensive listing of almost thirty Standard Operating Procedures (SOPs) For use in the laboratory, in academic and government institutions and industrial settings Those readers will appreciate the research that validates and updates cyanotoxin monitoring and analysis plus adding to approaches for setting standard methods that can be applied worldwide. Wayne Carmichael, Analytical and Bioanalytical Chemistry (2018).

Pharmacology

Author : Miles Hacker
Publisher : Academic Press
ISBN 13 : 0080919227
Total Pages : 607 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Pharmacology by : Miles Hacker

Download or read book Pharmacology written by Miles Hacker and published by Academic Press. This book was released on 2009-06-19 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker et al. to help train new drug researchers. The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process. The book is aimed at advanced undergraduates and beginning graduate students in medical, pharmacy, and graduate schools looking for a solid introduction to the basic science of pharmacology and envisioning careers in drug research. Uses individual drugs to explain molecular actions Full color art program explains molecular and chemical concepts graphically Logical structure reflecting the current state of pharmacology and translational research Covers such intricacies as drug resistance and cell death Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool

Freshwater Microbiology

Author : Suhaib A. Bandh
Publisher : Academic Press
ISBN 13 : 012817496X
Total Pages : 450 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Freshwater Microbiology by : Suhaib A. Bandh

Download or read book Freshwater Microbiology written by Suhaib A. Bandh and published by Academic Press. This book was released on 2019-08-01 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Freshwater Microbiology: Perspectives of Bacterial Dynamics in Lake Ecosystems provides a comprehensive and systematic analysis of microbial ecology in lakes. It offers basic information on how well the bacterial community composition varies along the spatio-temporal and trophic gradients along with the evaluation of the bioindicator species of bacteria so as to act as a key to predict the trophic status of lake ecosystems. The book helps to identify the factors of potential importance in structuring the bacterial communities in lakes as it delves into the dynamics and diversity of bacterial community composition in relation to various water quality parameters. It helps to identify the possibility of bioremediation plans and devising future policy decisions, with better conservation and management practices. Provides a comprehensive and systematic analysis of microbial ecology Helps to identify the factors of potential importance in structuring the bacterial community composition Gives insight into the bacterial diversity of freshwater lake ecosystems along with their industrial potential Caters to the needs and aspirations of students and professional researchers

Small Animal Toxicology - E-Book

Author : Michael E. Peterson
Publisher : Elsevier Health Sciences
ISBN 13 : 0323241980
Total Pages : 928 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Small Animal Toxicology - E-Book by : Michael E. Peterson

Download or read book Small Animal Toxicology - E-Book written by Michael E. Peterson and published by Elsevier Health Sciences. This book was released on 2013-08-07 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnose and determine treatment for toxic exposures in small animals with this quick reference! Small Animal Toxicology, 3rd Edition covers hundreds of potentially toxic substances, providing the information you need to manage emergency treatment and prevent poisonings in companion animals. To help you identify an unknown poison, this guide provides a list of potential toxins based on clinical signs or symptoms. It also includes a NEW color insert with 85 full-color photographs of toxic plants and of lesions associated with various poisonings. Written by respected veterinarian Michael E. Peterson and board-certified veterinary toxicologist Patricia A. Talcott, along with a team of expert contributors, this edition covers a wide variety of topics including toxicodynamics, toxicokinetics, effective history taking, recognizing clinical signs of toxic exposures, managing emergencies, and supportive care of the poisoned patient. Comprehensive coverage of toxins/poisons includes the full range of substances from acetaminophen to zinc, including home products, prescription medicines, recreational drugs, and more. Guidelines to evaluation, diagnosis and treatment include examinations of the source, toxic dose, toxicokinetics, clinical signs, minimum database, confirming tests, treatment progress and differential diagnosis for each specific toxicant. Coverage of common poisonous substances includes grapes and raisins, nicotine, mercury, mushrooms, Christmas-time plants, and snake and spider venoms. Toxicological Concepts section provides information on toxicologic principles such as history taking, providing supportive care, and managing emergency treatment. General Exposures section addresses nontraditional toxicology such as indoor environmental air, pesticides, pharmaceuticals, and toxicities in pregnant and lactating animals. Miscellaneous Toxicant Groups section covers commonly encountered specific toxicants, the proper use of diagnostic laboratories, use of human poison control centers, and antidotes for specific toxins. More than 50 international contributors provide up-to-date, authoritative advice on treating poisonings and intoxications. 8 NEW chapters cover topics including legal considerations in toxicology cases, responding to mass exposures, and poisonings in birds, small mammals, and geriatric patients. NEW color insert shows 85 of the most commonly encountered toxic substances for at-a-glance identification. UPDATED Signs and Symptoms index makes it easier to find information on a toxic agent by presenting signs rather than requiring the formulation of a diagnosis. UPDATED information on agents most likely to cause a toxic reaction includes natural flea products and an expanded section on human medications. NEW quick-access format with bold headings and convenient tables and boxes allows quick retrieval of information in emergency situations.

Forensic Plant Science

Author : Jane H Bock
Publisher : Academic Press
ISBN 13 : 0128015810
Total Pages : 228 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Forensic Plant Science by : Jane H Bock

Download or read book Forensic Plant Science written by Jane H Bock and published by Academic Press. This book was released on 2015-11-17 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic botany is the application of plant science to the resolution of legal questions. A plant’s anatomy and its ecological requirements are in some cases species specific and require taxonomic verification; correct interpretation of botanical evidence can give vital information about a crime scene or a suspect or victim. The use of botanical evidence in legal investigations in North America is relatively recent. The first botanical testimony to be heard in a North American court concerned the kidnapping and murder of Charles Lindbergh’s baby boy and the conviction of Bruno Hauptmann in 1935. Today, forensic botany encompasses numerous subdisciplines of plant science, such as plant anatomy, taxonomy, ecology, palynology, and diatomology, and interfaces with other disciplines, e.g., molecular biology, limnology and oceanography.Forensic Plant Science presents chapters on plant science evidence, plant anatomy, plant taxonomic evidence, plant ecology, case studies for all of the above, as well as the educational pathways for the future of forensic plant science. Provides techniques, collection methods, and analysis of digested plant materials Shows how to identify plants of use for crime scene and associated evidence in criminal cases The book’s companion website: http://booksite.elsevier.com/9780128014752, will host a microscopic atlas of common food plants

Veterinary Toxicology for Australia and New Zealand

Author : Rosalind Dalefield
Publisher : Elsevier
ISBN 13 : 0127999124
Total Pages : 630 pages
Book Rating : 4.1/5 (279 download)

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Book Synopsis Veterinary Toxicology for Australia and New Zealand by : Rosalind Dalefield

Download or read book Veterinary Toxicology for Australia and New Zealand written by Rosalind Dalefield and published by Elsevier. This book was released on 2017-06-23 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: Veterinary Toxicology for Australia and New Zealand is a reference suited to the unique challenges of veterinary practice in Australia and New Zealand. Both streamlined and thorough in its coverage of poisons and treatments for those locations, this focused approach allows readers to quickly find relevant information that is presented in a concise and logical manner that is useful to clinicians. The authors draw upon a wealth of knowledge of the particularities of toxicology in Australia and New Zealand to present readers with the up-to-date information required to efficiently and effectively diagnose and treat their patients. Highlights toxins of specific concern in Australia and New Zealand Structures information in a logical way so that it can be located quickly Offers up-to-date information on current and emerging risks

Industrial Gums

Author : Roy Whistler
Publisher : Elsevier
ISBN 13 : 0323161316
Total Pages : 820 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Industrial Gums by : Roy Whistler

Download or read book Industrial Gums written by Roy Whistler and published by Elsevier. This book was released on 2012-12-02 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt: Industrial Gums: Polysaccharides and their Derivatives, Second Edition covers the biochemical approaches to the modification and production of natural synthetic gums. This book is organized into two main parts encompassing 31 chapters. The first part deals with natural gums, including seaweed extracts, plant exudates and extracts, seed gums, and animal extracts. Considerable chapters in this part discuss the preparation, structure, derivatives, biosynthesis, and economics of these natural gums. The second part explores the industrial production, structure, and properties of synthetic gums, such as scleroglucan, dextrans, and starch and cellulose derivatives. Scientists, research workers, and manufacturers of both natural and synthetically prepared gums will find this book invaluable.