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Download or read book Binding Time written by Mark Halpern and published by Intellect Books. This book was released on 1990 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of related but independent and critical essays addressing the relationship within the computing world between intellectual constructs, thought experiments, theories, theorems, proofs, and observable facts.
Book Synopsis The Time Bind by : Arlie Russell Hochschild
Download or read book The Time Bind written by Arlie Russell Hochschild and published by Macmillan. This book was released on 1997-05-15 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hochschild's groundbreaking study exposes our crunch-time world and reveals how, after the first shift at work and the second at home, comes the third, and hardest, shift of repairing the damage created by the first two.
Download or read book Time-binding written by Alfred Korzybski and published by . This book was released on 1924 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Thermodynamics and Kinetics of Drug Binding by : György Keserü
Download or read book Thermodynamics and Kinetics of Drug Binding written by György Keserü and published by John Wiley & Sons. This book was released on 2015-03-09 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors.
Download or read book The Binding written by Bridget Collins and published by HarperCollins. This book was released on 2019-04-09 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: NATIONAL BESTSELLER A NEW YORK TIMES BOOK REVIEW EDITORS' CHOICE Proclaimed as “truly spellbinding,” a “great fable” that “functions as transporting romance” by the Guardian, the runaway #1 international bestseller "A rich, gothic entertainment that explores what books have trapped inside them and reminds us of the power of storytelling. Spellbinding.” — TRACY CHEVALIER Imagine you could erase grief. Imagine you could remove pain. Imagine you could hide the darkest, most horrifying secret. Forever. Young Emmett Farmer is working in the fields when a strange letter arrives summoning him away from his family. He is to begin an apprenticeship as a Bookbinder—a vocation that arouses fear, superstition, and prejudice amongst their small community, but one neither he nor his parents can afford to refuse. For as long as he can recall, Emmett has been drawn to books, even though they are strictly forbidden. Bookbinding is a sacred calling, Seredith informs her new apprentice, and he is a binder born. Under the old woman’s watchful eye, Emmett learns to hand-craft the elegant leather-bound volumes. Within each one they will capture something unique and extraordinary: a memory. If there’s something you want to forget, a binder can help. If there’s something you need to erase, they can assist. Within the pages of the books they create, secrets are concealed and the past is locked away. In a vault under his mentor’s workshop rows upon rows of books are meticulously stored. But while Seredith is an artisan, there are others of their kind, avaricious and amoral tradesman who use their talents for dark ends—and just as Emmett begins to settle into his new circumstances, he makes an astonishing discovery: one of the books has his name on it. Soon, everything he thought he understood about his life will be dramatically rewritten. An unforgettable novel of enchantment, mystery, memory, and forbidden love, The Binding is a beautiful homage to the allure and life-changing power of books—and a reminder to us all that knowledge can be its own kind of magic.
Download or read book Binding Vows written by Catherine Bybee and published by . This book was released on 2013-01-01 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Duncan MacCoinnich’s task… Travel to the twenty-first century Renaissance Faire, deflower the Druid virgins, and go home. Only his job is not so easily accomplished with the virgin in question, Tara McAllister. Time is running out. The evil is closing in on them both. Tara finds Duncan irresistible after what was supposed to be a mock Hand-fasting binds them. When Duncan whisks her to his home in Scotland she could accept that. But, can she forgive him for taking away her modern life when she finds herself in the sixteenth century? And is it love they feel? Or something else?
Book Synopsis Reversible Ligand Binding by : Andrea Bellelli
Download or read book Reversible Ligand Binding written by Andrea Bellelli and published by John Wiley & Sons. This book was released on 2018-01-09 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the physical background of ligand binding and instructs on how experiments should be designed and analyzed Reversible Ligand Binding: Theory and Experiment discusses the physical background of protein-ligand interactions—providing a comprehensive view of the various biochemical considerations that govern reversible, as well as irreversible, ligand binding. Special consideration is devoted to enzymology, a field usually treated separately from ligand binding, but actually governed by identical thermodynamic relationships. Attention is given to the design of the experiment, which aids in showing clear evidence of biochemical features that may otherwise escape notice. Classical experiments are reviewed in order to further highlight the importance of the design of the experiment. Overall, the book supplies students with the understanding that is necessary for interpreting ligand binding experiments, formulating plausible reaction schemes, and analyzing the data according to the chosen model(s). Topics covered include: theory of ligand binding to monomeric proteins; practical considerations and commonly encountered problems; oligomeric proteins with multiple binding sites; ligand binding kinetics; hemoglobin and its ligands; single-substrate enzymes and their inhibitors; two-substrate enzymes and their inhibitors; and rapid kinetic methods for studying enzyme reactions. Bridges theory of ligand binding and allostery with experiments Applies historical and physical insight to provide a clear understanding of ligand binding Written by a renowned author with long-standing research and teaching expertise in the area of ligand binding and allostery Based on FEBS Advanced Course lectures on the topic Reversible Ligand Binding: Theory and Experiment is an ideal text reference for students and scientists involved in biophysical chemistry, physical biochemistry, biophysics, molecular biology, protein engineering, drug design, pharmacology, physiology, biotechnology, and bioengineering.
Download or read book The Law Times written by and published by . This book was released on 1904 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Receptor Binding Techniques by : Mary Keen
Download or read book Receptor Binding Techniques written by Mary Keen and published by Springer Science & Business Media. This book was released on 1999 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cutting-edge collection of step-by-step experimental protocols demonstrates
Book Synopsis Dynamics and Mechanism of DNA-Bending Proteins in Binding Site Recognition by : Yogambigai Velmurugu
Download or read book Dynamics and Mechanism of DNA-Bending Proteins in Binding Site Recognition written by Yogambigai Velmurugu and published by Springer. This book was released on 2016-11-29 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a novel approach that combines high temporal resolution of the laser T-jump technique with unique sets of fluorescent probes, this study unveils previously unresolved DNA dynamics during search and recognition by an architectural DNA bending protein and two DNA damage recognition proteins. Many cellular processes involve special proteins that bind to specific DNA sites with high affinity. How these proteins recognize their sites while rapidly searching amidst ~3 billion nonspecific sites in genomic DNA remains an outstanding puzzle. Structural studies show that proteins severely deform DNA at specific sites and indicate that DNA deformability is a key factor in site-specific recognition. However, the dynamics of DNA deformations have been difficult to capture, thus obscuring our understanding of recognition mechanisms. The experiments presented in this thesis uncover, for the first time, rapid (~100-500 microseconds) DNA unwinding/bending attributed to nonspecific interrogation, prior to slower (~5-50 milliseconds) DNA kinking/bending/nucleotide-flipping during recognition. These results help illuminate how a searching protein interrogates DNA deformability and eventually “stumbles” upon its target site. Submillisecond interrogation may promote preferential stalling of the rapidly scanning protein at cognate sites, thus enabling site-recognition. Such multi-step search-interrogation-recognition processes through dynamic conformational changes may well be common to the recognition mechanisms for diverse DNA-binding proteins.
Book Synopsis Brain Receptor Methodologies by : Paul J. Marangos
Download or read book Brain Receptor Methodologies written by Paul J. Marangos and published by Academic Press. This book was released on 2013-10-22 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Receptor Methodologies: Part B Amino Acids. Peptides. Psychoactive Drugs is the second of the two-part first volume of the Neurobiological Research series, which provides a comprehensive view of various subdisciplines within neurobiology. The first volume (Parts A and B) deals with the area of neurotransmitter and neuromodulator receptors in brain; future volumes will cover the subdisciplines of neuroanatomy, neurophysiology, brain-specific macromolecules, neurochemistry, and behavioral neurobiology. It is hoped that the series will be of equal value for both basic as well as clinical scientists Part B continues from Part A with the remainder of Section II, specific receptor binding methodologies. Subsection II,B deals with receptors for amino acids and neuropeptides and covers areas including GABA, glycine, carnosine, opiates, bombesin, CCK, TRH, and substance P. Amino acids probably represent the majority of brain neurotransmitter substances, at least relative to the amines and acetylcholine, although with the exception of GABA, the amino acids remain relatively uncharacterized in brain. Their further study should receive high priority.
Book Synopsis Biosensors: Kinetics of Binding and Dissociation Using Fractals by : Ajit Sadana
Download or read book Biosensors: Kinetics of Binding and Dissociation Using Fractals written by Ajit Sadana and published by Elsevier. This book was released on 2003-12-17 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title brings to the attention of researchers in the industry, and in academia, the application of fractals to help in modeling the analyte/receptor binding and dissociation kinetics on biosensor surfaces.The work builds on that done in Engineering Biosensors: Kinetics and Design Applications, published by Academic Press in 2002. In particular, more examples are provided of where biosensors may be effectively used. This sequel is extremely timely, given the anticipation that the applications and reliance on biosensors will increase due to the advances in miniaturization, (wireless) communications, and the development of new materials (especially biological and chemical). Other applications of biosensors on the increase can be found in: the protection of civilian structures and infrastructures; protection from possible biological and chemical threats; health care; energy; food safety; and the environment to name a few. Covers all areas of applications of biosensors No other book on biosensors describes the kinetics of binding Provides numerous examples of where biosensors may be used
Book Synopsis Mathematical Philosophy by : Cassius Jackson Keyser
Download or read book Mathematical Philosophy written by Cassius Jackson Keyser and published by . This book was released on 1922 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Shakespeare's Binding Language by : John Kerrigan
Download or read book Shakespeare's Binding Language written by John Kerrigan and published by Oxford University Press. This book was released on 2016 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shakespeare's Binding Language is an innovative, substantial but highly readable study exploring the significance in Shakespeare's plays of oaths, vows, contracts, pledges and the other verbal and performative acts by which characters commit themselves to the truth of things past, present, and to come.
Book Synopsis The Law Times Reports of Cases Decided in the House of Lords, the Privy Council, the Court of Appeal ... [new Series]. by :
Download or read book The Law Times Reports of Cases Decided in the House of Lords, the Privy Council, the Court of Appeal ... [new Series]. written by and published by . This book was released on 1883 with total page 802 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Wörterbuch der Elektronik, Datentechnik, Telekommunikation und Medien by : Victor Ferretti
Download or read book Wörterbuch der Elektronik, Datentechnik, Telekommunikation und Medien written by Victor Ferretti and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 1033 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first edition was published, new technologies have emerged, especially in the area of convergence of computing and communications, accompanied by a lot of new technical terms. This third expanded and updated edition has been adaptetd to cope with this situation. The number of entries has been incremented by 35%. This dictionary offers a valuable guide to navigate through the entanglement of German and English terminology. The lexicographic concept (indication of the subject field for every term, short definitions, references to synonyms, antonyms, general and derivative terms) has been maintained, as well as the tabular layout.
Book Synopsis Fractal Binding and Dissociation Kinetics for Different Biosensor Applications by : Ajit Sadana
Download or read book Fractal Binding and Dissociation Kinetics for Different Biosensor Applications written by Ajit Sadana and published by Elsevier. This book was released on 2005-07-06 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosensors are portable and convenient devices that permit the rapid and reliable analysis of substances. They are increasingly used in healthcare, drug design, environmental monitoring and the detection of biological, chemical, and toxic agents. Fractal Binding and Dissociation Kinetics for Different Biosensor Applications focuses on two areas of expanding biosensor development that include (a) the detection of biological and chemical pathogens in the atmosphere, and (b) biomedical applications, especially in healthcare. The author provides numerous examples of practical uses, particularly biomedical applications and the detection of biological or chemical pathogens. This book also contains valuable information dedicated to the economics of biosensors. After reading this book, the reader will gain invaluable insight into how biosensors work and how they may be used more effectively. * No other book provides a detailed kinetic analysis of the binding and dissociation reactions occurring on the biosensor surfaces * Packed with examples of practical uses of biosensors * Includes chapters dedicated to the economics of biosensors
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