Behavioral Models and the Analysis of Drug Action

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Author :
Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 526 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Behavioral Models and the Analysis of Drug Action by : Michael Y. Spiegelstein

Download or read book Behavioral Models and the Analysis of Drug Action written by Michael Y. Spiegelstein and published by Elsevier Science & Technology. This book was released on 1982 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Methods of Behavior Analysis in Neuroscience

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Publisher : CRC Press
ISBN 13 : 1420041819
Total Pages : 341 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Methods of Behavior Analysis in Neuroscience by : Jerry J. Buccafusco

Download or read book Methods of Behavior Analysis in Neuroscience written by Jerry J. Buccafusco and published by CRC Press. This book was released on 2000-08-29 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic

Pathways of Addiction

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Publisher : National Academies Press
ISBN 13 : 0309055334
Total Pages : 330 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Pathways of Addiction by : Institute of Medicine

Download or read book Pathways of Addiction written by Institute of Medicine and published by National Academies Press. This book was released on 1996-11-01 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug abuse persists as one of the most costly and contentious problems on the nation's agenda. Pathways of Addiction meets the need for a clear and thoughtful national research agenda that will yield the greatest benefit from today's limited resources. The committee makes its recommendations within the public health framework and incorporates diverse fields of inquiry and a range of policy positions. It examines both the demand and supply aspects of drug abuse. Pathways of Addiction offers a fact-filled, highly readable examination of drug abuse issues in the United States, describing findings and outlining research needs in the areas of behavioral and neurobiological foundations of drug abuse. The book covers the epidemiology and etiology of drug abuse and discusses several of its most troubling health and social consequences, including HIV, violence, and harm to children. Pathways of Addiction looks at the efficacy of different prevention interventions and the many advances that have been made in treatment research in the past 20 years. The book also examines drug treatment in the criminal justice setting and the effectiveness of drug treatment under managed care. The committee advocates systematic study of the laws by which the nation attempts to control drug use and identifies the research questions most germane to public policy. Pathways of Addiction provides a strategic outline for wise investment of the nation's research resources in drug abuse. This comprehensive and accessible volume will have widespread relevanceâ€"to policymakers, researchers, research administrators, foundation decisionmakers, healthcare professionals, faculty and students, and concerned individuals.

Planaria: A Model for Drug Action and Abuse

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Publisher : CRC Press
ISBN 13 : 1498713599
Total Pages : 150 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Planaria: A Model for Drug Action and Abuse by : Robert B. Raffa

Download or read book Planaria: A Model for Drug Action and Abuse written by Robert B. Raffa and published by CRC Press. This book was released on 2008-12-03 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of drug action has benefitted greatly from the development and use of in vivo model systems. In model systems, manipulations and observations can be more rigorously controlled and screens of novel therapeutic agents can be more safely conducted.No single model system provides all of the possible advantages. At one end, mammalian models al

Behavioural Models in Psychopharmacology

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Publisher : Cambridge University Press
ISBN 13 : 9780521391924
Total Pages : 564 pages
Book Rating : 4.3/5 (919 download)

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Book Synopsis Behavioural Models in Psychopharmacology by : Paul Willner

Download or read book Behavioural Models in Psychopharmacology written by Paul Willner and published by Cambridge University Press. This book was released on 1991-02-21 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Behavioural models in psychopharmacology are used for different purposes. The main concern of industrial psychopharmacologists is specifically to develop new and improved drugs for the treatment of mental disorders, while basic scientists use animal models to investigate the underlying nature of such conditions. The important distinction between these different perspectives is made explicit for the first time in this book. By considering such conditions as anxiety, depression, mania and schizophrenia, feeding disorders, dementia, and drug dependence, this book provides a comprehensive and critical review of the adequacy of the behavioural procedures used by psychopharmacologists to model psychiatric disorders. Graduate students and research workers in pscyhopharmacology, from both academic and industrial spheres, as well as clinicians, will find this book of considerable interest.

Animal Models in Psychopharmacology

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Publisher : Birkhäuser
ISBN 13 : 3034864191
Total Pages : 447 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Animal Models in Psychopharmacology by : Olivier

Download or read book Animal Models in Psychopharmacology written by Olivier and published by Birkhäuser. This book was released on 2013-11-21 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 1712 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Catalog by : National Library of Medicine (U.S.)

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1712 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Handbook of Psychopharmacology

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Publisher : Springer Science & Business Media
ISBN 13 : 146131819X
Total Pages : 652 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Handbook of Psychopharmacology by : Leslie Iversen

Download or read book Handbook of Psychopharmacology written by Leslie Iversen and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volumes 7 and 8 of the Handbook were published in 1977. In Volume 7 methods for studying unconditioned and conditioned behavior were reviewed. Attention was given to both ethological methods and operant conditioning techniques as applied to some selected aspects of behavior. Genetic, developmental, and environmental factors influencing behavior were also discussed. In Volume 8, neurotransmitter systems, and in par ticular brain circuits, were discussed in relation to behavior and to the effects of psychoactive drugs on behavior. The coverage was not exhaus tive because of space limitations. The topics selected for review were, at the time, the focus of considerable experimental effort; they included homeostasis-motivated behaviors: sleep, locomotion, feeding, drinking, and sexual behavior. Brain dopamine systems were therefore discussed in depth, since they were already known to be centrally involved in motivated behaviors. Learning mechanisms and emotion were reviewed in the remaining chapters. In 1984 we initiated an update of behavioral pharmacology to review areas of progress within the same scope as the earlier volumes. This update continues in Volume 19. Among the contributions are several that represent important advances in analyzing behavior and the use of more sophisticated methods to define the effect of drugs on particular aspects of behavior. The chapters by Blundell on feeding and Miczek on aggres sion illustrate the sophistication of modern ethopharmacology.

NIDA Research Monograph

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Author :
Publisher :
ISBN 13 :
Total Pages : 696 pages
Book Rating : 4.M/5 ( download)

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Book Synopsis NIDA Research Monograph by :

Download or read book NIDA Research Monograph written by and published by . This book was released on 1976 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Behaviour Analysis and Contemporary Psychology

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Publisher : Taylor & Francis
ISBN 13 : 100064913X
Total Pages : 308 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Behaviour Analysis and Contemporary Psychology by : C. F. Lowe

Download or read book Behaviour Analysis and Contemporary Psychology written by C. F. Lowe and published by Taylor & Francis. This book was released on 2022-11-01 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in 1985, Behaviour Analysis and Contemporary Psychology presents chapters from the first European Meeting on the Experimental Analysis of Behaviour. The book is divided into six parts and provides a useful account of issues and work in behaviour analysis by both European and North American contributors at the time. The first part provides an introduction, with following parts looking at behaviourist and ethological approaches; determinants of human operant behaviour; fundamental research and behaviour modification; recent developments in the behavioural analysis of drug effects; ending with an overview of contemporary behaviourism.

Advances in Behavioral Pharmacology

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Publisher : Psychology Press
ISBN 13 : 1317768078
Total Pages : 394 pages
Book Rating : 4.3/5 (177 download)

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Book Synopsis Advances in Behavioral Pharmacology by : T. Thompson

Download or read book Advances in Behavioral Pharmacology written by T. Thompson and published by Psychology Press. This book was released on 2014-04-04 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1987. Advances in Behavioral Pharmacology has broadened its scope in an attempt to provide a better understanding of behavioral actions of drugs and their applied implications. Each volume will be increasingly thematic and successive volumes will cover a wider range of issues. Some publications in this series, such as the present volume 6, Neurobehavioral Pharmacology, will primarily explore relations between neurochemistry and related areas of neurobiology and behavioral pharmacology.

Handbook of Perception and Action

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Publisher : Academic Press
ISBN 13 : 0080533167
Total Pages : 461 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Handbook of Perception and Action by : Odmar Neumann

Download or read book Handbook of Perception and Action written by Odmar Neumann and published by Academic Press. This book was released on 1996-04-04 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Perception and Action overviews state-of-the-art research in these two areas, while also stressing the functional relationships between them. The three-volume set will be useful toresearchers, technicians, graduate students, and final-year undergraduates in psychology, developmental psychology, speech and hearing, neuropsychology, neuroscience, and physiology.

Experimental Psychopharmacology

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Publisher : Springer Science & Business Media
ISBN 13 : 1592594611
Total Pages : 499 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Experimental Psychopharmacology by : Andrew J. Greenshaw

Download or read book Experimental Psychopharmacology written by Andrew J. Greenshaw and published by Springer Science & Business Media. This book was released on 1987-04-07 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychopharmacology may be defined as the study of the effects of drugs on behavior. As an established scientific discipline, this is a relatively new area of research. Despite its short history, however, psychopharmacology has achieved a considerable degree of sophistication in the variety of experi mental approaches that are currently employed. Consequently, the interpretation of data accumulated through the use of various experimental laboratory techniques has become increasingly difficult and complex. Numerous excelIent texts and review articles are available that serve to outline recent progress in psychopharmacology (particularly the Handbook of Psychopharmacology series, edited by L. L. Iversen, S. D. Iversen, and S. H. Synder). Volumes such as these serve to usefully review the available litera ture without attempting a critical appraisal of the utility and limitations of methods and the difficulties of interpreting empirical data. Such conceptual and methodological problems are now an issue of paramount importance in studying the behavioral effects of drugs. The present volume can be regarded as a "conceptual cookbook" that examines the utility and limitations of various experimental approaches commonly taken in psychopharmacology. This practically oriented text should prove particularly useful for pharmacologists and neurochemists who have no formal training in behavioral research and require an intro duction to the actuallaboratory practice of the field. In addition, the useful and informative treatment of current issues in psychopharmacology will undoubtedly appeal to the majority of active researchers.

Drug-like Properties: Concepts, Structure Design and Methods

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Publisher : Elsevier
ISBN 13 : 0080557619
Total Pages : 549 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Drug-like Properties: Concepts, Structure Design and Methods by : Li Di

Download or read book Drug-like Properties: Concepts, Structure Design and Methods written by Li Di and published by Elsevier. This book was released on 2010-07-26 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. - Serves as an essential working handbook aimed at scientists and students in medicinal chemistry - Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies - Discusses improvements in pharmacokinetics from a practical chemist's standpoint

Animal and Translational Models for CNS Drug Discovery: Reward Deficit Disorders

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Publisher : Academic Press
ISBN 13 : 0080920403
Total Pages : 426 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Animal and Translational Models for CNS Drug Discovery: Reward Deficit Disorders by : Robert A. McArthur

Download or read book Animal and Translational Models for CNS Drug Discovery: Reward Deficit Disorders written by Robert A. McArthur and published by Academic Press. This book was released on 2009-02-24 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reward Deficit Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for reward deficit disorders such as alcohol dependence, nicotine dependence, heroin and cocaine addiction, obesity, and gambling and impulse control disorders. Reward Deficit Disorders has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. Reward Deficit Disorders also has a section dedicated to the specifics of the regulatory aspects to abuse liability testing. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This is the third volume in the three volume-set, Animal and Translational Models for CNS Drug Discovery 978-0-12-373861-5, which is also available for purchase individually. - Provides clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process - Critical evaluation of animal and translational models improving transition from drug discovery and clinical development - Emphasizes what results mean to the overall drug discovery process - Explores issues in clinical trial design and conductance in each therapeutic area - Neurological Disorders is available for purchase individually.

Problems of Drug Dependence

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Publisher :
ISBN 13 :
Total Pages : 690 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Problems of Drug Dependence by : College on Problems of Drug Dependence (U.S.). Scientific Meeting

Download or read book Problems of Drug Dependence written by College on Problems of Drug Dependence (U.S.). Scientific Meeting and published by . This book was released on 1993 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Development of Sex Differences and Similarities in Behavior

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Publisher : Springer Science & Business Media
ISBN 13 : 9401117098
Total Pages : 492 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis The Development of Sex Differences and Similarities in Behavior by : M. Haug

Download or read book The Development of Sex Differences and Similarities in Behavior written by M. Haug and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: M. HAUG Universite Louis Pasteur, Laboratoire de Psychophysi%gie, URA 1295, 7, rue de /'Universite, 67000 Strasbourg, France This varied and impressive volume is a record of the major presentations at the NATO sponsored Advanced Research Workshop on The Development of Sex Differences and Similarities in Behaviour held at the Chateau de Bonas, Gers, France July 14-18, 1992. It is fitting that a meeting evaluating masculine and feminine 'characteristics' was located in the Gascony region immortalised in Alexandre Dumas epic, macho tale of The Three Musketeers. It is even more satisfying that Marc HAUG the French Director (a D' Artagnan equivalent) was ably assisted by a US/French Consortium of three co-Directors (Drs. Richard E. WHALEN, Claude ARON and Kathie L. OLSEN). The ARW also provided opportunities to explore the region around the Chateau, to appreciate the complex history of the area and to sample armagnac and other local gastronomic creations. A lively and varied cultural programme (classics to jazz) was also provided to maintain the interests and enthusiasms of the participants.