Author : Yuzuru Kanakura
Publisher : Springer
ISBN 13 : 4431560033
Total Pages : 351 pages
Book Rating : 4.4/5 (315 download)
Book Synopsis Paroxysmal Nocturnal Hemoglobinuria by : Yuzuru Kanakura
Download or read book Paroxysmal Nocturnal Hemoglobinuria written by Yuzuru Kanakura and published by Springer. This book was released on 2017-01-16 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews the fundamental understanding of this potentially life-threatening disease and the advances in treatment that have been achieved with the use of the monoclonal antibody eculizumab. Although the PIGA gene has been known for many years, the mechanism of clonal dominance in paroxysmal nocturnal hemoglobinuria is still largely unknown. This book, Paroxysmal Nocturnal Hemoglobinuria, discusses the direction of continuing research in this area, as well as the potential for the development of management guidelines. It serves as a valuable source of information for both basic scientists and physicians, especially immunologists targeting GPI-anchored proteins and complements, and hematologists specializing in bone marrow failure.