Bayesian Model Selection For High Dimensional High Throughput Data

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Statistical Analysis for High-Dimensional Data

Author : Arnoldo Frigessi
Publisher : Springer
ISBN 13 : 3319270990
Total Pages : 313 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Statistical Analysis for High-Dimensional Data by : Arnoldo Frigessi

Download or read book Statistical Analysis for High-Dimensional Data written by Arnoldo Frigessi and published by Springer. This book was released on 2016-02-16 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book features research contributions from The Abel Symposium on Statistical Analysis for High Dimensional Data, held in Nyvågar, Lofoten, Norway, in May 2014. The focus of the symposium was on statistical and machine learning methodologies specifically developed for inference in “big data” situations, with particular reference to genomic applications. The contributors, who are among the most prominent researchers on the theory of statistics for high dimensional inference, present new theories and methods, as well as challenging applications and computational solutions. Specific themes include, among others, variable selection and screening, penalised regression, sparsity, thresholding, low dimensional structures, computational challenges, non-convex situations, learning graphical models, sparse covariance and precision matrices, semi- and non-parametric formulations, multiple testing, classification, factor models, clustering, and preselection. Highlighting cutting-edge research and casting light on future research directions, the contributions will benefit graduate students and researchers in computational biology, statistics and the machine learning community.

Advanced Mean Field Methods

Author : Manfred Opper
Publisher : MIT Press
ISBN 13 : 9780262150545
Total Pages : 300 pages
Book Rating : 4.1/5 (55 download)

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Book Synopsis Advanced Mean Field Methods by : Manfred Opper

Download or read book Advanced Mean Field Methods written by Manfred Opper and published by MIT Press. This book was released on 2001 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the theoretical foundations of advanced mean field methods, explores the relation between the different approaches, examines the quality of the approximation obtained, and demonstrates their application to various areas of probabilistic modeling. A major problem in modern probabilistic modeling is the huge computational complexity involved in typical calculations with multivariate probability distributions when the number of random variables is large. Because exact computations are infeasible in such cases and Monte Carlo sampling techniques may reach their limits, there is a need for methods that allow for efficient approximate computations. One of the simplest approximations is based on the mean field method, which has a long history in statistical physics. The method is widely used, particularly in the growing field of graphical models. Researchers from disciplines such as statistical physics, computer science, and mathematical statistics are studying ways to improve this and related methods and are exploring novel application areas. Leading approaches include the variational approach, which goes beyond factorizable distributions to achieve systematic improvements; the TAP (Thouless-Anderson-Palmer) approach, which incorporates correlations by including effective reaction terms in the mean field theory; and the more general methods of graphical models. Bringing together ideas and techniques from these diverse disciplines, this book covers the theoretical foundations of advanced mean field methods, explores the relation between the different approaches, examines the quality of the approximation obtained, and demonstrates their application to various areas of probabilistic modeling.

Asymptotic Statistics

Author : A. W. van der Vaart
Publisher : Cambridge University Press
ISBN 13 : 9780521784504
Total Pages : 470 pages
Book Rating : 4.7/5 (845 download)

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Book Synopsis Asymptotic Statistics by : A. W. van der Vaart

Download or read book Asymptotic Statistics written by A. W. van der Vaart and published by Cambridge University Press. This book was released on 2000-06-19 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an introduction to the field of asymptotic statistics. The treatment is both practical and mathematically rigorous. In addition to most of the standard topics of an asymptotics course, including likelihood inference, M-estimation, the theory of asymptotic efficiency, U-statistics, and rank procedures, the book also presents recent research topics such as semiparametric models, the bootstrap, and empirical processes and their applications. The topics are organized from the central idea of approximation by limit experiments, which gives the book one of its unifying themes. This entails mainly the local approximation of the classical i.i.d. set up with smooth parameters by location experiments involving a single, normally distributed observation. Thus, even the standard subjects of asymptotic statistics are presented in a novel way. Suitable as a graduate or Master s level statistics text, this book will also give researchers an overview of the latest research in asymptotic statistics.

Bayesian Thinking, Modeling and Computation

Author :
Publisher : Elsevier
ISBN 13 : 0080461174
Total Pages : 1062 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Bayesian Thinking, Modeling and Computation by :

Download or read book Bayesian Thinking, Modeling and Computation written by and published by Elsevier. This book was released on 2005-11-29 with total page 1062 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes how to develop Bayesian thinking, modelling and computation both from philosophical, methodological and application point of view. It further describes parametric and nonparametric Bayesian methods for modelling and how to use modern computational methods to summarize inferences using simulation. The book covers wide range of topics including objective and subjective Bayesian inferences with a variety of applications in modelling categorical, survival, spatial, spatiotemporal, Epidemiological, software reliability, small area and micro array data. The book concludes with a chapter on how to teach Bayesian thoughts to nonstatisticians. Critical thinking on causal effects Objective Bayesian philosophy Nonparametric Bayesian methodology Simulation based computing techniques Bioinformatics and Biostatistics

Case Studies in Applied Bayesian Data Science

Author : Kerrie L. Mengersen
Publisher : Springer Nature
ISBN 13 : 3030425533
Total Pages : 415 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Case Studies in Applied Bayesian Data Science by : Kerrie L. Mengersen

Download or read book Case Studies in Applied Bayesian Data Science written by Kerrie L. Mengersen and published by Springer Nature. This book was released on 2020-05-28 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting a range of substantive applied problems within Bayesian Statistics along with their Bayesian solutions, this book arises from a research program at CIRM in France in the second semester of 2018, which supported Kerrie Mengersen as a visiting Jean-Morlet Chair and Pierre Pudlo as the local Research Professor. The field of Bayesian statistics has exploded over the past thirty years and is now an established field of research in mathematical statistics and computer science, a key component of data science, and an underpinning methodology in many domains of science, business and social science. Moreover, while remaining naturally entwined, the three arms of Bayesian statistics, namely modelling, computation and inference, have grown into independent research fields. While the research arms of Bayesian statistics continue to grow in many directions, they are harnessed when attention turns to solving substantive applied problems. Each such problem set has its own challenges and hence draws from the suite of research a bespoke solution. The book will be useful for both theoretical and applied statisticians, as well as practitioners, to inspect these solutions in the context of the problems, in order to draw further understanding, awareness and inspiration.

Feature Selection for High-Dimensional Data

Author : Verónica Bolón-Canedo
Publisher : Springer
ISBN 13 : 3319218581
Total Pages : 163 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Feature Selection for High-Dimensional Data by : Verónica Bolón-Canedo

Download or read book Feature Selection for High-Dimensional Data written by Verónica Bolón-Canedo and published by Springer. This book was released on 2015-10-05 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a coherent and comprehensive approach to feature subset selection in the scope of classification problems, explaining the foundations, real application problems and the challenges of feature selection for high-dimensional data. The authors first focus on the analysis and synthesis of feature selection algorithms, presenting a comprehensive review of basic concepts and experimental results of the most well-known algorithms. They then address different real scenarios with high-dimensional data, showing the use of feature selection algorithms in different contexts with different requirements and information: microarray data, intrusion detection, tear film lipid layer classification and cost-based features. The book then delves into the scenario of big dimension, paying attention to important problems under high-dimensional spaces, such as scalability, distributed processing and real-time processing, scenarios that open up new and interesting challenges for researchers. The book is useful for practitioners, researchers and graduate students in the areas of machine learning and data mining.

High-Dimensional Single Cell Analysis

Author : Harris G. Fienberg
Publisher : Springer
ISBN 13 : 364254827X
Total Pages : 224 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis High-Dimensional Single Cell Analysis by : Harris G. Fienberg

Download or read book High-Dimensional Single Cell Analysis written by Harris G. Fienberg and published by Springer. This book was released on 2014-04-22 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume highlights the most interesting biomedical and clinical applications of high-dimensional flow and mass cytometry. It reviews current practical approaches used to perform high-dimensional experiments and addresses key bioinformatic techniques for the analysis of data sets involving dozens of parameters in millions of single cells. Topics include single cell cancer biology; studies of the human immunome; exploration of immunological cell types such as CD8+ T cells; decipherment of signaling processes of cancer; mass-tag cellular barcoding; analysis of protein interactions by proximity ligation assays; Cytobank, a platform for the analysis of cytometry data; computational analysis of high-dimensional flow cytometric data; computational deconvolution approaches for the description of intracellular signaling dynamics and hyperspectral cytometry. All 10 chapters of this book have been written by respected experts in their fields. It is an invaluable reference book for both basic and clinical researchers.

Statistical Inference from High Dimensional Data

Author : Carlos Fernandez-Lozano
Publisher : MDPI
ISBN 13 : 3036509445
Total Pages : 314 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Statistical Inference from High Dimensional Data by : Carlos Fernandez-Lozano

Download or read book Statistical Inference from High Dimensional Data written by Carlos Fernandez-Lozano and published by MDPI. This book was released on 2021-04-28 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: • Real-world problems can be high-dimensional, complex, and noisy • More data does not imply more information • Different approaches deal with the so-called curse of dimensionality to reduce irrelevant information • A process with multidimensional information is not necessarily easy to interpret nor process • In some real-world applications, the number of elements of a class is clearly lower than the other. The models tend to assume that the importance of the analysis belongs to the majority class and this is not usually the truth • The analysis of complex diseases such as cancer are focused on more-than-one dimensional omic data • The increasing amount of data thanks to the reduction of cost of the high-throughput experiments opens up a new era for integrative data-driven approaches • Entropy-based approaches are of interest to reduce the dimensionality of high-dimensional data

Advances in Statistical Bioinformatics

Author : Kim-Anh Do
Publisher : Cambridge University Press
ISBN 13 : 1107027527
Total Pages : 499 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Advances in Statistical Bioinformatics by : Kim-Anh Do

Download or read book Advances in Statistical Bioinformatics written by Kim-Anh Do and published by Cambridge University Press. This book was released on 2013-06-10 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the integration of high-throughput bioinformatics data from multiple platforms to inform our understanding of the functional consequences of genomic alterations.

Genes & Signals

Author : Mark Ptashne
Publisher : CSHL Press
ISBN 13 : 9780879696337
Total Pages : 212 pages
Book Rating : 4.6/5 (963 download)

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Book Synopsis Genes & Signals by : Mark Ptashne

Download or read book Genes & Signals written by Mark Ptashne and published by CSHL Press. This book was released on 2002 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: P. 103.

Bayesian Modeling in Bioinformatics

Author : Dipak K. Dey
Publisher : CRC Press
ISBN 13 : 1420070185
Total Pages : 466 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Bayesian Modeling in Bioinformatics by : Dipak K. Dey

Download or read book Bayesian Modeling in Bioinformatics written by Dipak K. Dey and published by CRC Press. This book was released on 2010-09-03 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian Modeling in Bioinformatics discusses the development and application of Bayesian statistical methods for the analysis of high-throughput bioinformatics data arising from problems in molecular and structural biology and disease-related medical research, such as cancer. It presents a broad overview of statistical inference, clustering, and c

Model-Based Clustering and Classification for Data Science

Author : Charles Bouveyron
Publisher : Cambridge University Press
ISBN 13 : 1108640591
Total Pages : 447 pages
Book Rating : 4.1/5 (86 download)

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Book Synopsis Model-Based Clustering and Classification for Data Science by : Charles Bouveyron

Download or read book Model-Based Clustering and Classification for Data Science written by Charles Bouveyron and published by Cambridge University Press. This book was released on 2019-07-25 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cluster analysis finds groups in data automatically. Most methods have been heuristic and leave open such central questions as: how many clusters are there? Which method should I use? How should I handle outliers? Classification assigns new observations to groups given previously classified observations, and also has open questions about parameter tuning, robustness and uncertainty assessment. This book frames cluster analysis and classification in terms of statistical models, thus yielding principled estimation, testing and prediction methods, and sound answers to the central questions. It builds the basic ideas in an accessible but rigorous way, with extensive data examples and R code; describes modern approaches to high-dimensional data and networks; and explains such recent advances as Bayesian regularization, non-Gaussian model-based clustering, cluster merging, variable selection, semi-supervised and robust classification, clustering of functional data, text and images, and co-clustering. Written for advanced undergraduates in data science, as well as researchers and practitioners, it assumes basic knowledge of multivariate calculus, linear algebra, probability and statistics.

Inference for Sparse and Asymmetric Signals in High Dimensional Data with Applications to Statistical Genomics

Author : Min Zhang
Publisher :
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Inference for Sparse and Asymmetric Signals in High Dimensional Data with Applications to Statistical Genomics by : Min Zhang

Download or read book Inference for Sparse and Asymmetric Signals in High Dimensional Data with Applications to Statistical Genomics written by Min Zhang and published by . This book was released on 2005 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Big Data and Information Theory

Author : Jiuping Xu
Publisher : Routledge
ISBN 13 : 1000591719
Total Pages : 128 pages
Book Rating : 4.0/5 (5 download)

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Book Synopsis Big Data and Information Theory by : Jiuping Xu

Download or read book Big Data and Information Theory written by Jiuping Xu and published by Routledge. This book was released on 2022-06-02 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Big Data and Information Theory are a binding force between various areas of knowledge that allow for societal advancement. Rapid development of data analytic and information theory allows companies to store vast amounts of information about production, inventory, service, and consumer activities. More powerful CPUs and cloud computing make it possible to do complex optimization instead of using heuristic algorithms, as well as instant rather than offline decision-making. The era of "big data" challenges includes analysis, capture, curation, search, sharing, storage, transfer, visualization, and privacy violations. Big data calls for better integration of optimization, statistics, and data mining. In response to these challenges this book brings together leading researchers and engineers to exchange and share their experiences and research results about big data and information theory applications in various areas. This book covers a broad range of topics including statistics, data mining, data warehouse implementation, engineering management in large-scale infrastructure systems, data-driven sustainable supply chain network, information technology service offshoring project issues, online rumors governance, preliminary cost estimation, and information system project selection. The chapters in this book were originally published in the journal, International Journal of Management Science and Engineering Management.

Model Validation and Uncertainty Quantification, Volume 3

Author : Sez Atamturktur
Publisher : Springer
ISBN 13 : 3319297546
Total Pages : 366 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Model Validation and Uncertainty Quantification, Volume 3 by : Sez Atamturktur

Download or read book Model Validation and Uncertainty Quantification, Volume 3 written by Sez Atamturktur and published by Springer. This book was released on 2016-06-27 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Model Validation and Uncertainty Quantifi cation, Volume 3. Proceedings of the 34th IMAC, A Conference and Exposition on Dynamics of Multiphysical Systems: From Active Materials to Vibroacoustics, 2016, the third volume of ten from the Conference brings together contributions to this important area of research and engineering. Th e collection presents early findings and case studies on fundamental and applied aspects of Structural Dynamics, including papers on: • Uncertainty Quantifi cation & Model Validation • Uncertainty Propagation in Structural Dynamics • Bayesian & Markov Chain Monte Carlo Methods • Practical Applications of MVUQ • Advances in MVUQ & Model Updating • Robustness in Design & Validation • Verifi cation & Validation Methods

High-Dimensional Covariance Estimation

Author : Mohsen Pourahmadi
Publisher : John Wiley & Sons
ISBN 13 : 1118573668
Total Pages : 204 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis High-Dimensional Covariance Estimation by : Mohsen Pourahmadi

Download or read book High-Dimensional Covariance Estimation written by Mohsen Pourahmadi and published by John Wiley & Sons. This book was released on 2013-05-28 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods for estimating sparse and large covariance matrices Covariance and correlation matrices play fundamental roles in every aspect of the analysis of multivariate data collected from a variety of fields including business and economics, health care, engineering, and environmental and physical sciences. High-Dimensional Covariance Estimation provides accessible and comprehensive coverage of the classical and modern approaches for estimating covariance matrices as well as their applications to the rapidly developing areas lying at the intersection of statistics and machine learning. Recently, the classical sample covariance methodologies have been modified and improved upon to meet the needs of statisticians and researchers dealing with large correlated datasets. High-Dimensional Covariance Estimation focuses on the methodologies based on shrinkage, thresholding, and penalized likelihood with applications to Gaussian graphical models, prediction, and mean-variance portfolio management. The book relies heavily on regression-based ideas and interpretations to connect and unify many existing methods and algorithms for the task. High-Dimensional Covariance Estimation features chapters on: Data, Sparsity, and Regularization Regularizing the Eigenstructure Banding, Tapering, and Thresholding Covariance Matrices Sparse Gaussian Graphical Models Multivariate Regression The book is an ideal resource for researchers in statistics, mathematics, business and economics, computer sciences, and engineering, as well as a useful text or supplement for graduate-level courses in multivariate analysis, covariance estimation, statistical learning, and high-dimensional data analysis.

Encyclopedia of Biopharmaceutical Statistics - Four Volume Set

Author : Shein-Chung Chow
Publisher : CRC Press
ISBN 13 : 135111025X
Total Pages : 4031 pages
Book Rating : 4.3/5 (511 download)

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Book Synopsis Encyclopedia of Biopharmaceutical Statistics - Four Volume Set by : Shein-Chung Chow

Download or read book Encyclopedia of Biopharmaceutical Statistics - Four Volume Set written by Shein-Chung Chow and published by CRC Press. This book was released on 2018-09-03 with total page 4031 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition in 2000, there has been an explosive growth of literature in biopharmaceutical research and development of new medicines. This encyclopedia (1) provides a comprehensive and unified presentation of designs and analyses used at different stages of the drug development process, (2) gives a well-balanced summary of current regulatory requirements, and (3) describes recently developed statistical methods in the pharmaceutical sciences. Features of the Fourth Edition: 1. 78 new and revised entries have been added for a total of 308 chapters and a fourth volume has been added to encompass the increased number of chapters. 2. Revised and updated entries reflect changes and recent developments in regulatory requirements for the drug review/approval process and statistical designs and methodologies. 3. Additional topics include multiple-stage adaptive trial design in clinical research, translational medicine, design and analysis of biosimilar drug development, big data analytics, and real world evidence for clinical research and development. 4. A table of contents organized by stages of biopharmaceutical development provides easy access to relevant topics. About the Editor: Shein-Chung Chow, Ph.D. is currently an Associate Director, Office of Biostatistics, U.S. Food and Drug Administration (FDA). Dr. Chow is an Adjunct Professor at Duke University School of Medicine, as well as Adjunct Professor at Duke-NUS, Singapore and North Carolina State University. Dr. Chow is the Editor-in-Chief of the Journal of Biopharmaceutical Statistics and the Chapman & Hall/CRC Biostatistics Book Series and the author of 28 books and over 300 methodology papers. He was elected Fellow of the American Statistical Association in 1995.