Bayesian Approaches in Oncology Using R and OpenBUGS

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Publisher : CRC Press
ISBN 13 : 1000330060
Total Pages : 188 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Bayesian Approaches in Oncology Using R and OpenBUGS by : Atanu Bhattacharjee

Download or read book Bayesian Approaches in Oncology Using R and OpenBUGS written by Atanu Bhattacharjee and published by CRC Press. This book was released on 2020-12-14 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian Approaches in Oncology Using R and OpenBUGS serves two audiences: those who are familiar with the theory and applications of bayesian approach and wish to learn or enhance their skills in R and OpenBUGS, and those who are enrolled in R and OpenBUGS-based course for bayesian approach implementation. For those who have never used R/OpenBUGS, the book begins with a self-contained introduction to R that lays the foundation for later chapters. Many books on the bayesian approach and the statistical analysis are advanced, and many are theoretical. While most of them do cover the objective, the fact remains that data analysis can not be performed without actually doing it, and this means using dedicated statistical software. There are several software packages, all with their specific objective. Finally, all packages are free to use, are versatile with problem-solving, and are interactive with R and OpenBUGS. This book continues to cover a range of techniques related to oncology that grow in statistical analysis. It intended to make a single source of information on Bayesian statistical methodology for oncology research to cover several dimensions of statistical analysis. The book explains data analysis using real examples and includes all the R and OpenBUGS codes necessary to reproduce the analyses. The idea is to overall extending the Bayesian approach in oncology practice. It presents four sections to the statistical application framework: Bayesian in Clinical Research and Sample Size Calcuation Bayesian in Time-to-Event Data Analysis Bayesian in Longitudinal Data Analysis Bayesian in Diagnostics Test Statistics This book is intended as a first course in bayesian biostatistics for oncology students. An oncologist can find useful guidance for implementing bayesian in research work. It serves as a practical guide and an excellent resource for learning the theory and practice of bayesian methods for the applied statistician, biostatistician, and data scientist.

Bayesian Approaches in Oncology Using R and OpenBUGS

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Author :
Publisher : CRC Press
ISBN 13 : 1000329984
Total Pages : 260 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Bayesian Approaches in Oncology Using R and OpenBUGS by : Atanu Bhattacharjee

Download or read book Bayesian Approaches in Oncology Using R and OpenBUGS written by Atanu Bhattacharjee and published by CRC Press. This book was released on 2020-12-21 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian Approaches in Oncology Using R and OpenBUGS serves two audiences: those who are familiar with the theory and applications of bayesian approach and wish to learn or enhance their skills in R and OpenBUGS, and those who are enrolled in R and OpenBUGS-based course for bayesian approach implementation. For those who have never used R/OpenBUGS, the book begins with a self-contained introduction to R that lays the foundation for later chapters. Many books on the bayesian approach and the statistical analysis are advanced, and many are theoretical. While most of them do cover the objective, the fact remains that data analysis can not be performed without actually doing it, and this means using dedicated statistical software. There are several software packages, all with their specific objective. Finally, all packages are free to use, are versatile with problem-solving, and are interactive with R and OpenBUGS. This book continues to cover a range of techniques related to oncology that grow in statistical analysis. It intended to make a single source of information on Bayesian statistical methodology for oncology research to cover several dimensions of statistical analysis. The book explains data analysis using real examples and includes all the R and OpenBUGS codes necessary to reproduce the analyses. The idea is to overall extending the Bayesian approach in oncology practice. It presents four sections to the statistical application framework: Bayesian in Clinical Research and Sample Size Calcuation Bayesian in Time-to-Event Data Analysis Bayesian in Longitudinal Data Analysis Bayesian in Diagnostics Test Statistics This book is intended as a first course in bayesian biostatistics for oncology students. An oncologist can find useful guidance for implementing bayesian in research work. It serves as a practical guide and an excellent resource for learning the theory and practice of bayesian methods for the applied statistician, biostatistician, and data scientist.

Bayesian Computation with R

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Publisher : Springer Science & Business Media
ISBN 13 : 0387922989
Total Pages : 304 pages
Book Rating : 4.3/5 (879 download)

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Book Synopsis Bayesian Computation with R by : Jim Albert

Download or read book Bayesian Computation with R written by Jim Albert and published by Springer Science & Business Media. This book was released on 2009-04-20 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been dramatic growth in the development and application of Bayesian inference in statistics. Berger (2000) documents the increase in Bayesian activity by the number of published research articles, the number of books,andtheextensivenumberofapplicationsofBayesianarticlesinapplied disciplines such as science and engineering. One reason for the dramatic growth in Bayesian modeling is the availab- ity of computational algorithms to compute the range of integrals that are necessary in a Bayesian posterior analysis. Due to the speed of modern c- puters, it is now possible to use the Bayesian paradigm to ?t very complex models that cannot be ?t by alternative frequentist methods. To ?t Bayesian models, one needs a statistical computing environment. This environment should be such that one can: write short scripts to de?ne a Bayesian model use or write functions to summarize a posterior distribution use functions to simulate from the posterior distribution construct graphs to illustrate the posterior inference An environment that meets these requirements is the R system. R provides a wide range of functions for data manipulation, calculation, and graphical d- plays. Moreover, it includes a well-developed, simple programming language that users can extend by adding new functions. Many such extensions of the language in the form of packages are easily downloadable from the Comp- hensive R Archive Network (CRAN).

Bayesian Analysis with R for Drug Development

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Publisher : CRC Press
ISBN 13 : 1351585932
Total Pages : 262 pages
Book Rating : 4.3/5 (515 download)

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Book Synopsis Bayesian Analysis with R for Drug Development by : Harry Yang

Download or read book Bayesian Analysis with R for Drug Development written by Harry Yang and published by CRC Press. This book was released on 2019-06-26 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug development is an iterative process. The recent publications of regulatory guidelines further entail a lifecycle approach. Blending data from disparate sources, the Bayesian approach provides a flexible framework for drug development. Despite its advantages, the uptake of Bayesian methodologies is lagging behind in the field of pharmaceutical development. Written specifically for pharmaceutical practitioners, Bayesian Analysis with R for Drug Development: Concepts, Algorithms, and Case Studies, describes a wide range of Bayesian applications to problems throughout pre-clinical, clinical, and Chemistry, Manufacturing, and Control (CMC) development. Authored by two seasoned statisticians in the pharmaceutical industry, the book provides detailed Bayesian solutions to a broad array of pharmaceutical problems. Features Provides a single source of information on Bayesian statistics for drug development Covers a wide spectrum of pre-clinical, clinical, and CMC topics Demonstrates proper Bayesian applications using real-life examples Includes easy-to-follow R code with Bayesian Markov Chain Monte Carlo performed in both JAGS and Stan Bayesian software platforms Offers sufficient background for each problem and detailed description of solutions suitable for practitioners with limited Bayesian knowledge Harry Yang, Ph.D., is Senior Director and Head of Statistical Sciences at AstraZeneca. He has 24 years of experience across all aspects of drug research and development and extensive global regulatory experiences. He has published 6 statistical books, 15 book chapters, and over 90 peer-reviewed papers on diverse scientific and statistical subjects, including 15 joint statistical works with Dr. Novick. He is a frequent invited speaker at national and international conferences. He also developed statistical courses and conducted training at the FDA and USP as well as Peking University. Steven Novick, Ph.D., is Director of Statistical Sciences at AstraZeneca. He has extensively contributed statistical methods to the biopharmaceutical literature. Novick is a skilled Bayesian computer programmer and is frequently invited to speak at conferences, having developed and taught courses in several areas, including drug-combination analysis and Bayesian methods in clinical areas. Novick served on IPAC-RS and has chaired several national statistical conferences.

Bayesian Precision Medicine

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Publisher : CRC Press
ISBN 13 : 1040026664
Total Pages : 330 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Bayesian Precision Medicine by : Peter F. Thall

Download or read book Bayesian Precision Medicine written by Peter F. Thall and published by CRC Press. This book was released on 2024-05-07 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bayesian Precision Medicine presents modern Bayesian statistical models and methods for identifying treatments tailored to individual patients using their prognostic variables and predictive biomarkers. The process of evaluating and comparing treatments is explained and illustrated by practical examples, followed by a discussion of causal analysis and its relationship to statistical inference. A wide array of modern Bayesian clinical trial designs are presented, including applications to many oncology trials. The later chapters describe Bayesian nonparametric regression analyses of datasets arising from multistage chemotherapy for acute leukemia, allogeneic stem cell transplantation, and targeted agents for treating advanced breast cancer. Features: Describes the connection between causal analysis and statistical inference Reviews modern personalized Bayesian clinical trial designs for dose-finding, treatment screening, basket trials, enrichment, incorporating historical data, and confirmatory treatment comparison, illustrated by real-world applications Presents adaptive methods for clustering similar patient subgroups to improve efficiency Describes Bayesian nonparametric regression analyses of real-world datasets from oncology Provides pointers to software for implementation Bayesian Precision Medicine is primarily aimed at biostatisticians and medical researchers who desire to apply modern Bayesian methods to their own clinical trials and data analyses. It also might be used to teach a special topics course on precision medicine using a Bayesian approach to postgraduate biostatistics students. The main goal of the book is to show how Bayesian thinking can provide a practical scientific basis for tailoring treatments to individual patients.

Bayesian Disease Mapping

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Publisher : Chapman and Hall/CRC
ISBN 13 : 9781584888406
Total Pages : 0 pages
Book Rating : 4.8/5 (884 download)

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Book Synopsis Bayesian Disease Mapping by : Andrew B. Lawson

Download or read book Bayesian Disease Mapping written by Andrew B. Lawson and published by Chapman and Hall/CRC. This book was released on 2008-08-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on data commonly found in public health databases and clinical settings, Bayesian Disease Mapping: Hierarchical Modeling in Spatial Epidemiology provides an overview of the main areas of Bayesian hierarchical modeling and its application to the geographical analysis of disease. The book explores a range of topics in Bayesian inference and modeling, including Markov chain Monte Carlo methods, Gibbs sampling, the Metropolis–Hastings algorithm, goodness-of-fit measures, and residual diagnostics. It also focuses on special topics, such as cluster detection; space-time modeling; and multivariate, survival, and longitudinal analyses. The author explains how to apply these methods to disease mapping using numerous real-world data sets pertaining to cancer, asthma, epilepsy, foot and mouth disease, influenza, and other diseases. In the appendices, he shows how R and WinBUGS can be useful tools in data manipulation and simulation. Applying Bayesian methods to the modeling of georeferenced health data, Bayesian Disease Mapping proves that the application of these approaches to biostatistical problems can yield important insights into data.

A Hierarchical Bayesian Approach to Regression and Its Application to Predicting Survival Times in Cancer

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Publisher :
ISBN 13 : 9783832252168
Total Pages : 212 pages
Book Rating : 4.2/5 (521 download)

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Book Synopsis A Hierarchical Bayesian Approach to Regression and Its Application to Predicting Survival Times in Cancer by : Lars Kaderali

Download or read book A Hierarchical Bayesian Approach to Regression and Its Application to Predicting Survival Times in Cancer written by Lars Kaderali and published by . This book was released on 2006 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Reviews in Surgical Oncology

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Publisher : Frontiers Media SA
ISBN 13 : 2832526020
Total Pages : 207 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Reviews in Surgical Oncology by : Cesare Ruffolo

Download or read book Reviews in Surgical Oncology written by Cesare Ruffolo and published by Frontiers Media SA. This book was released on 2023-08-14 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bayesian Modeling Using WinBUGS

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Publisher : John Wiley & Sons
ISBN 13 : 1118210352
Total Pages : 477 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Bayesian Modeling Using WinBUGS by : Ioannis Ntzoufras

Download or read book Bayesian Modeling Using WinBUGS written by Ioannis Ntzoufras and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: A hands-on introduction to the principles of Bayesian modeling using WinBUGS Bayesian Modeling Using WinBUGS provides an easily accessible introduction to the use of WinBUGS programming techniques in a variety of Bayesian modeling settings. The author provides an accessible treatment of the topic, offering readers a smooth introduction to the principles of Bayesian modeling with detailed guidance on the practical implementation of key principles. The book begins with a basic introduction to Bayesian inference and the WinBUGS software and goes on to cover key topics, including: Markov Chain Monte Carlo algorithms in Bayesian inference Generalized linear models Bayesian hierarchical models Predictive distribution and model checking Bayesian model and variable evaluation Computational notes and screen captures illustrate the use of both WinBUGS as well as R software to apply the discussed techniques. Exercises at the end of each chapter allow readers to test their understanding of the presented concepts and all data sets and code are available on the book's related Web site. Requiring only a working knowledge of probability theory and statistics, Bayesian Modeling Using WinBUGS serves as an excellent book for courses on Bayesian statistics at the upper-undergraduate and graduate levels. It is also a valuable reference for researchers and practitioners in the fields of statistics, actuarial science, medicine, and the social sciences who use WinBUGS in their everyday work.

Computational Bayesian Statistics

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Publisher : Cambridge University Press
ISBN 13 : 1108481035
Total Pages : 256 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Computational Bayesian Statistics by : M. Antónia Amaral Turkman

Download or read book Computational Bayesian Statistics written by M. Antónia Amaral Turkman and published by Cambridge University Press. This book was released on 2019-02-28 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This integrated introduction to fundamentals, computation, and software is your key to understanding and using advanced Bayesian methods.

Network Meta-Analysis for Decision-Making

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Publisher : John Wiley & Sons
ISBN 13 : 1118647505
Total Pages : 484 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Network Meta-Analysis for Decision-Making by : Sofia Dias

Download or read book Network Meta-Analysis for Decision-Making written by Sofia Dias and published by John Wiley & Sons. This book was released on 2018-03-19 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide to network meta-analysis with examples and code In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish which interventions are effective and cost-effective. Often a single study will not provide the answers and it is desirable to synthesise evidence from multiple sources, usually randomised controlled trials. This book takes an approach to evidence synthesis that is specifically intended for decision making when there are two or more treatment alternatives being evaluated, and assumes that the purpose of every synthesis is to answer the question "for this pre-identified population of patients, which treatment is 'best'?" A comprehensive, coherent framework for network meta-analysis (mixed treatment comparisons) is adopted and estimated using Bayesian Markov Chain Monte Carlo methods implemented in the freely available software WinBUGS. Each chapter contains worked examples, exercises, solutions and code that may be adapted by readers to apply to their own analyses. This book can be used as an introduction to evidence synthesis and network meta-analysis, its key properties and policy implications. Examples and advanced methods are also presented for the more experienced reader. Methods used throughout this book can be applied consistently: model critique and checking for evidence consistency are emphasised. Methods are based on technical support documents produced for NICE Decision Support Unit, which support the NICE Methods of Technology Appraisal. Code presented is also the basis for the code used by the ISPOR Task Force on Indirect Comparisons. Includes extensive carefully worked examples, with thorough explanations of how to set out data for use in WinBUGS and how to interpret the output. Network Meta-Analysis for Decision Making will be of interest to decision makers, medical statisticians, health economists, and anyone involved in Health Technology Assessment including the pharmaceutical industry.

Bayesian Methods in Pharmaceutical Research

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Publisher : CRC Press
ISBN 13 : 1351718673
Total Pages : 547 pages
Book Rating : 4.3/5 (517 download)

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Book Synopsis Bayesian Methods in Pharmaceutical Research by : Emmanuel Lesaffre

Download or read book Bayesian Methods in Pharmaceutical Research written by Emmanuel Lesaffre and published by CRC Press. This book was released on 2020-04-15 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the early 2000s, there has been increasing interest within the pharmaceutical industry in the application of Bayesian methods at various stages of the research, development, manufacturing, and health economic evaluation of new health care interventions. In 2010, the first Applied Bayesian Biostatistics conference was held, with the primary objective to stimulate the practical implementation of Bayesian statistics, and to promote the added-value for accelerating the discovery and the delivery of new cures to patients. This book is a synthesis of the conferences and debates, providing an overview of Bayesian methods applied to nearly all stages of research and development, from early discovery to portfolio management. It highlights the value associated with sharing a vision with the regulatory authorities, academia, and pharmaceutical industry, with a view to setting up a common strategy for the appropriate use of Bayesian statistics for the benefit of patients. The book covers: Theory, methods, applications, and computing Bayesian biostatistics for clinical innovative designs Adding value with Real World Evidence Opportunities for rare, orphan diseases, and pediatric development Applied Bayesian biostatistics in manufacturing Decision making and Portfolio management Regulatory perspective and public health policies Statisticians and data scientists involved in the research, development, and approval of new cures will be inspired by the possible applications of Bayesian methods covered in the book. The methods, applications, and computational guidance will enable the reader to apply Bayesian methods in their own pharmaceutical research.

Bayesian Adaptive Methods for Clinical Trials

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Publisher : CRC Press
ISBN 13 : 1439825513
Total Pages : 316 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Bayesian Adaptive Methods for Clinical Trials by : Scott M. Berry

Download or read book Bayesian Adaptive Methods for Clinical Trials written by Scott M. Berry and published by CRC Press. This book was released on 2010-07-19 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer's disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV. Written by leading pioneers of Bayesian clinical trial designs, Bayesian Adapti

Applied Spatial Data Analysis with R

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Publisher : Springer Science & Business Media
ISBN 13 : 1461476186
Total Pages : 414 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Applied Spatial Data Analysis with R by : Roger S. Bivand

Download or read book Applied Spatial Data Analysis with R written by Roger S. Bivand and published by Springer Science & Business Media. This book was released on 2013-06-21 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applied Spatial Data Analysis with R, second edition, is divided into two basic parts, the first presenting R packages, functions, classes and methods for handling spatial data. This part is of interest to users who need to access and visualise spatial data. Data import and export for many file formats for spatial data are covered in detail, as is the interface between R and the open source GRASS GIS and the handling of spatio-temporal data. The second part showcases more specialised kinds of spatial data analysis, including spatial point pattern analysis, interpolation and geostatistics, areal data analysis and disease mapping. The coverage of methods of spatial data analysis ranges from standard techniques to new developments, and the examples used are largely taken from the spatial statistics literature. All the examples can be run using R contributed packages available from the CRAN website, with code and additional data sets from the book's own website. Compared to the first edition, the second edition covers the more systematic approach towards handling spatial data in R, as well as a number of important and widely used CRAN packages that have appeared since the first edition. This book will be of interest to researchers who intend to use R to handle, visualise, and analyse spatial data. It will also be of interest to spatial data analysts who do not use R, but who are interested in practical aspects of implementing software for spatial data analysis. It is a suitable companion book for introductory spatial statistics courses and for applied methods courses in a wide range of subjects using spatial data, including human and physical geography, geographical information science and geoinformatics, the environmental sciences, ecology, public health and disease control, economics, public administration and political science. The book has a website where complete code examples, data sets, and other support material may be found: http://www.asdar-book.org. The authors have taken part in writing and maintaining software for spatial data handling and analysis with R in concert since 2003.

The Evaluation of Surrogate Endpoints

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Publisher : Springer Science & Business Media
ISBN 13 : 9780387202778
Total Pages : 440 pages
Book Rating : 4.2/5 (27 download)

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Book Synopsis The Evaluation of Surrogate Endpoints by : Geert Molenberghs

Download or read book The Evaluation of Surrogate Endpoints written by Geert Molenberghs and published by Springer Science & Business Media. This book was released on 2005-02-28 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers the latest research on a sensitive and controversial topic in a professional and well researched manner. Provides practical outlook as well as model guidelines and software tools that should be of interest to people who use the software tools described and those who do not. Related title by Co-author Geert Molenbergh has sold more than 3500 copies world wide. Provides dual viewpoints: from scientists in the industry as well as regulatory authorities.

The Oxford Handbook of Political Methodology

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Publisher : Oxford Handbooks of Political
ISBN 13 : 9780199286546
Total Pages : 880 pages
Book Rating : 4.2/5 (865 download)

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Book Synopsis The Oxford Handbook of Political Methodology by : Janet M. Box-Steffensmeier

Download or read book The Oxford Handbook of Political Methodology written by Janet M. Box-Steffensmeier and published by Oxford Handbooks of Political. This book was released on 2008 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Oxford Handbooks of Political Science are the essential guide to the state of political science today. With engaging contributions from major international scholars The Oxford Handbook of Political Methodology provides the key point of reference for anyone working throughout the discipline.

The Science of Health Disparities Research

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Publisher : John Wiley & Sons
ISBN 13 : 1119374812
Total Pages : 548 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis The Science of Health Disparities Research by : Irene Dankwa-Mullan

Download or read book The Science of Health Disparities Research written by Irene Dankwa-Mullan and published by John Wiley & Sons. This book was released on 2021-03-16 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrates the various disciplines of the science of health disparities in one comprehensive volume The Science of Health Disparities Research is an indispensable source of up-to-date information on clinical and translational health disparities science. Building upon the advances in health disparities research over the past decade, this authoritative volume informs policies and practices addressing the diseases, disorders, and gaps in health outcomes that are more prevalent in minority populations and socially disadvantaged communities. Contributions by recognized scholars and leaders in the field—featuring contemporary research, conceptual models, and a broad range of scientific perspectives—provide an interdisciplinary approach to reducing inequalities in population health, encouraging community engagement in the research process, and promoting social justice. In-depth chapters help readers better understand the specifics of minority health and health disparities while demonstrating the importance of advancing theory, refining measurement, improving investigative methods, and diversifying scientific research. In 26 chapters, the book examines topics including the etiology of health disparities research, the determinants of population health, research ethics, and research in African American, Asians, Latino, American Indian, and other vulnerable populations. Providing a unified framework on the principles and applications of the science of health disparities research, this important volume: Defines the field of health disparities science and suggests new directions in scholarship and research Explains basic definitions, principles, and concepts for identifying, understanding and addressing health disparities Provides guidance on both conducting health disparities research and translating the results Examines how social, historical and contemporary injustices may influence the health of racial and ethnic minorities Illustrates the increasing national and global importance of addressing health disparities Discusses population health training, capacity-building, and the transdisciplinary tools needed to advance health equity A significant contribution to the field, The Science of Health Disparities Research is an essential resource for students and basic and clinical researchers in genetics, population genetics, and public health, health care policymakers, and epidemiologists, medical students, and clinicians, particularly those working with minority, vulnerable, or underserved populations.