Molecular Biology of B Cells

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Publisher : Academic Press
ISBN 13 : 9780123979339
Total Pages : 0 pages
Book Rating : 4.9/5 (793 download)

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Book Synopsis Molecular Biology of B Cells by : Tasuku Honjo

Download or read book Molecular Biology of B Cells written by Tasuku Honjo and published by Academic Press. This book was released on 2014-12-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.

Janeway's Immunobiology

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Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

B Cell Differentiation Antigens

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Publisher :
ISBN 13 : 9788716094476
Total Pages : 159 pages
Book Rating : 4.0/5 (944 download)

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Book Synopsis B Cell Differentiation Antigens by :

Download or read book B Cell Differentiation Antigens written by and published by . This book was released on 1982 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt:

B-Lymphocyte Differentiation

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Publisher : CRC Press
ISBN 13 : 135108691X
Total Pages : 404 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis B-Lymphocyte Differentiation by : John C. Cambier

Download or read book B-Lymphocyte Differentiation written by John C. Cambier and published by CRC Press. This book was released on 2018-01-18 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the mechanisms of transmembrane signal transduction during B-Cell Activation, the Regulation of Gene Expression during B-Cell Differentiation, Anti-immunoglobulin antibody induction of B-Lymphocyte activation and differentiation in vivo and in vitro, Helper signals in B-Lymphocyte differentiation, Growth and differentiation of b-cell clones in vitro, B-Cell tumors as models of lymphocyte differentiation, and Memory b-cell activation, differentiation, and isotype switching.

B Cell Differentiation Antigens as Probes for Functional B Cell Subsets

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis B Cell Differentiation Antigens as Probes for Functional B Cell Subsets by : Brigitte T. Huber

Download or read book B Cell Differentiation Antigens as Probes for Functional B Cell Subsets written by Brigitte T. Huber and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

B Cell Receptor Signaling

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Publisher : Springer
ISBN 13 : 3319261339
Total Pages : 231 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis B Cell Receptor Signaling by : Tomohiro Kurosaki

Download or read book B Cell Receptor Signaling written by Tomohiro Kurosaki and published by Springer. This book was released on 2015-12-26 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details our current understanding of the architecture and signaling capabilities of the B cell antigen receptor (BCR) in health and disease. The first chapters review new insights into the assembly of BCR components and their organization on the cell surface. Subsequent contributions focus on the molecular interactions that connect the BCR with major intracellular signaling pathways such as Ca2+ mobilization, membrane phospholipid metabolism, nuclear translocation of NF-kB or the activation of Bruton’s Tyrosine Kinase and MAP kinases. These elements orchestrate cytoplasmic and nuclear responses as well as cytoskeleton dynamics for antigen internalization. Furthermore, a key mechanism of how B cells remember their cognate antigen is discussed in detail. Altogether, the discoveries presented provide a better understanding of B cell biology and help to explain some B cell-mediated pathogenicities, like autoimmune phenomena or the formation of B cell tumors, while also paving the way for eventually combating these diseases.

The Molecular Basis of B-Cell Differentiation and Function

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Publisher : Springer Science & Business Media
ISBN 13 : 1468470353
Total Pages : 173 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis The Molecular Basis of B-Cell Differentiation and Function by : M. Ferrarini

Download or read book The Molecular Basis of B-Cell Differentiation and Function written by M. Ferrarini and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: The progress in protein and nucleic acid chemistry together with improvements of the previously employed tissue culture techniques have led to the solution of problems such as that of the generation of antibody diversity or of the molecular structure of T and B cell membrane receptor for antigen which had challenged the past generations of immunologists. Thanks to this progress an impressive amount of knowledge has been accumulated on certain cell types that were relatively "mysterious" until recently. The B lymphocyte represents a typical example of such a cell. With these considerations in mind, we have started to organize a NATO summer school on "The molecular basis of B cell differentation and function" that had the specific aim of bringing up to date a selected number of young investigators. During the course, held in Santa Margheri ta Ligure, October 1-11, 1985 it became apparent that rather than a formal school we had organized an informal series of Workshops where both the Faculty members and the participants were discussing their own data in addition to reviewing the general progress in the field. The deep commi ttment of everyone to his research subj ect and the enthusiasm had caused this very successful change in the shape of the course. At the end we asked the members of the Faculty and the participants to write a summary of their data and of their point of view on selected subj ect s.

Differentiation of B Lymphocytes

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Publisher : Springer Science & Business Media
ISBN 13 : 3642718515
Total Pages : 156 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Differentiation of B Lymphocytes by : Christopher J. Paige

Download or read book Differentiation of B Lymphocytes written by Christopher J. Paige and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid progress continues to be made in understanding the molecular and cellular events that comprise B-Iymphocyte differentiation. This is due in part to the high level of inter est shown by many investigators from diverse disciplines, who find this subject suitable for addressing some of the fundamental issues of immunobiology. B-cell developmen tal models are being extensively used to investigate cell-cell interactions, molecular mediators of differentiation and proliferation, differential onset of gene programs, and gene rearrangement and expression, as well as the generation of the immune response itself. Not surprisingly, increased understanding of B-cell differentiation sometimes results from the application of new techniques that permit greater insight into the cells comprising the system and the genetic mechanisms by which these cells express their differentiative potential. However, experimental strategies based upon the novel application of established technologies have also led to the clarification of many issues, as well as to the discov ery of previously unrecognized problems. One problem, well recognized by those active in the field, is how to keep up with significant developments as they appear. The purpose of this book, part of a series devoted to analysing current issues in biology, is to help overcome this problem. No attempt at comprehensive cov erage of all of the issues has been made. Rather, a more thorough analysis of a few topics is presented.

Molecular Biology of The Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Leukocyte Typing II

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Publisher : Springer Science & Business Media
ISBN 13 : 1461248485
Total Pages : 547 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Leukocyte Typing II by : Ellis L. Reinherz

Download or read book Leukocyte Typing II written by Ellis L. Reinherz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt:

B Cell Differentiation

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Publisher :
ISBN 13 :
Total Pages : 174 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis B Cell Differentiation by :

Download or read book B Cell Differentiation written by and published by . This book was released on 1983 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Biology of B Cells

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Author :
Publisher : Elsevier
ISBN 13 : 0123984904
Total Pages : 587 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Molecular Biology of B Cells by : Tasuku Honjo

Download or read book Molecular Biology of B Cells written by Tasuku Honjo and published by Elsevier. This book was released on 2014-10-09 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. Covers signaling mechanisms regulating B cell differentiation Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab Contains studies on B cell tumors from various stages of B lymphocytes Offers an integrated view of all aspects of B cells to produce a normal immune response

T-Cell Dependent and Independent B-Cell Activation

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Publisher : CRC Press
ISBN 13 : 9780849368196
Total Pages : 314 pages
Book Rating : 4.3/5 (681 download)

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Book Synopsis T-Cell Dependent and Independent B-Cell Activation by : E. Charles Snow

Download or read book T-Cell Dependent and Independent B-Cell Activation written by E. Charles Snow and published by CRC Press. This book was released on 1990-12-19 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an analysis of the current subdisciplines comprising the study of humoral immune response. The first chapter presents a detailed discussion regarding the experimental and conceptual studies conducted prior to the mid-1970s that have served as a valuable research framework for investigators interested in the process by which B cells are activated following their exposure to antigens. Other chapters focus on topics such as membrane-associated proteins with important functional roles during B cell activation and differentiation; thymus-independent and thymus-dependent activation; mechanisms operative during B-T cell interactions, including the role of B cells as antigen-presenting cells; and the importance of soluble mediators. Additional topics include the regulatory role of T cells during B cell repertoire expression, memory development, tolerance, and autoimmunity. T-Cell Dependent and Independent B-Cell Activation is an important history and reference resource for humoral immune response investigators, as well as advanced graduate and medical students.

Leucocyte Typing III

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Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 1092 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Leucocyte Typing III by : Andrew J. McMichael

Download or read book Leucocyte Typing III written by Andrew J. McMichael and published by Oxford University Press, USA. This book was released on 1987 with total page 1092 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third international workshop on leucocyte typing antigens reports the results of collaborative experiments involving over 800 antibodies. This volume contains the first and only complete account of the experiments and the subsequent analyses, which produced a careful description of fifty human leucocyte antigens, twenty-four of them fully characterized for the first time. Antigens specific for or shared by T-Cells, B-Cells, activated lymphocytes, myeloid cells and platelets are featured. The papers detail their distribution, molecular structure and function, and discuss the role that the antigens may play in investigating and understanding pathological processes, particularly in leukemias and lymphomas.

Molecular Biology of B Cells

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Publisher : Elsevier
ISBN 13 : 0080479502
Total Pages : 629 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Molecular Biology of B Cells by : Tasuku Honjo

Download or read book Molecular Biology of B Cells written by Tasuku Honjo and published by Elsevier. This book was released on 2004-02-19 with total page 629 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molecular basis of many diseases due to B cell abnormality is also discussed. This definitive reference is directed at research level immunologists, molecular biologists and geneticists.

B Cells in Immunity and Tolerance

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Publisher : Springer Nature
ISBN 13 : 9811535329
Total Pages : 181 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis B Cells in Immunity and Tolerance by : Ji-Yang Wang

Download or read book B Cells in Immunity and Tolerance written by Ji-Yang Wang and published by Springer Nature. This book was released on 2020-04-22 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.

Normal and Malignant B-Cell

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 178985430X
Total Pages : 163 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Normal and Malignant B-Cell by : Mourad Aribi

Download or read book Normal and Malignant B-Cell written by Mourad Aribi and published by BoD – Books on Demand. This book was released on 2020-02-26 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: Normal and Malignant B-Cell is a collection of harmonious chapters contributed by different authors. This book sets out to describe the B-cell during different stages of ontogeny and the molecular mechanisms of its antigen receptor diversity. It also discusses the main clinical and etiopathogenic aspects when it is transformed into a malignant cell. The book will be interesting and useful for clinicians, biologists, researchers, teachers, and graduate students of both doctoral and master's degrees in the field of immunology.