Author : Doychin N. Angelov
Publisher : Springer Science & Business Media
ISBN 13 : 3540299319
Total Pages : 140 pages
Book Rating : 4.5/5 (42 download)
Book Synopsis Axonal Branching and Recovery of Coordinated Muscle Activity after Transsection of the Facial Nerve in Adult Rats by : Doychin N. Angelov
Download or read book Axonal Branching and Recovery of Coordinated Muscle Activity after Transsection of the Facial Nerve in Adult Rats written by Doychin N. Angelov and published by Springer Science & Business Media. This book was released on 2005-12-11 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Facial nerve surgery inevitably leads to partial pareses, abnormally associated movements and pathologically altered reflexes. The reason for this "post-paralytic syndrome" is the misdirected reinnervation of targets, which consists of two major components. First, due to malfunctioning axonal guidance, a muscle gets reinnervated by a "foreign" axon, that has been misrouted along a "wrong" fascicle. Second, the supernumerary collateral branches emerging from all transected axons simultaneously innervate antagonistic muscles and cause severe impairment of their coordinated activity. Since it is hardly possible to influence the first major component and improve the guidance of several thousands axons, the authors concentrated on the second major component and tried to reduce the collateral axonal branching.