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Autophagy At The Cell Tissue And Organismal Level
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Book Synopsis Autophagy at the Cell, Tissue and Organismal Level by : Eleftherios Karanasios
Download or read book Autophagy at the Cell, Tissue and Organismal Level written by Eleftherios Karanasios and published by Springer. This book was released on 2016-04-23 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation. A comprehensive list of useful antibodies for studying autophagy compiled as a community effort is included at the end. The book is intended for newcomers to the field, as well as more experienced researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms.
Book Synopsis Autophagy in Current Trends in Cellular Physiology and Pathology by : Nikolai Gorbunov
Download or read book Autophagy in Current Trends in Cellular Physiology and Pathology written by Nikolai Gorbunov and published by BoD – Books on Demand. This book was released on 2016-11-10 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy in Current Trends in Cellular Physiology and Pathology is addressed to one of the fundamental molecular mechanisms - autophagy- evolutionarily adopted by cells for processing of unnecessary or malfunctioned constituents and shaping intracellular structures, adjusting them to environmental conditions, aging, disease, neoplasia, and damages over their life period. Particular attention is paid to autophagy-mediated barrier processes of selective sequestration and recycling of impaired organelles and degradation of invading microorganisms, that is, the processes sustaining intrinsic resistance to stress, tissue degeneration, toxic exposures, and infections. The presented topics encompass personal experience and visions of the chapter contributors and the editors; the book chapters include a broad analysis of literature on biology of autophagy.
Book Synopsis Autophagy in Health and Disease by : Beverly Rothermel
Download or read book Autophagy in Health and Disease written by Beverly Rothermel and published by Elsevier. This book was released on 2021-09-23 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy in Health and Disease, Second Edition provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysiology. The book covers the history, trajectory of the research field, mechanisms of autophagy, and its regulation, developmental aspects, including stem cells, embryogenesis, hematopoiesis and paligenosis and focus on several systems, including Metabolic control and Diabetes, Cardiovascular, Nervous, Immune, Gastrointestinal, and Skeletal. The final chapters provide additional disease considerations, covering cancer, longevity, disease mechanisms, and the therapeutic targeting of autophagy. This book is invaluable to anyone looking for a broader understanding of autophagy outside their specific field
Book Synopsis Autophagy and Cancer by : Hong-Gang Wang
Download or read book Autophagy and Cancer written by Hong-Gang Wang and published by Springer Science & Business Media. This book was released on 2013-03-30 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the explosion of information on autophagy in cancer, this is an opportune time to speed the efforts to translate our current knowledge about autophagy regulation into better understanding of its role in cancer. This book will cover the latest advances in this area from the basics, such as the molecular machinery for autophagy induction and regulation, up to the current areas of interest such as modulation of autophagy and drug discovery for cancer prevention and treatment. The text will include an explanation on how autophagy can function in both oncogenesis and tumor suppression and a description of its function in tumor development and tumor suppression through its roles in cell survival, cell death, cell growth as well as its influences on inflammation, immunity, DNA damage, oxidative stress, tumor microenvironment, etc. The remaining chapters will cover topics on autophagy and cancer therapy. These pages will serve as a description on how the pro-survival function of autophagy may help cancer cells resist chemotherapy and radiation treatment as well as how the pro-death functions of autophagy may enhance cell death in response to cancer therapy, and how to target autophagy for cancer prevention and therapy − what to target and how to target it.
Download or read book Cell Death written by Tobias Ntuli and published by BoD – Books on Demand. This book was released on 2015-12-16 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study. Each contribution comes as a separate chapter complete in itself but directly related to the books topics and objectives. The target audience comprises scholars and specialists in the field.
Book Synopsis Molecular Biology of The Cell by : Bruce Alberts
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Stressed Heart by : Marianne J. Legato
Download or read book The Stressed Heart written by Marianne J. Legato and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Stressed Heart is truly unique in concept and will provide an eXCItmg adventure to the reader no matter what his or her field of expertise and interest. The title, although quite appropriate, does not adequately indicate the range of topics considered or the rational interrelationships among them. Indeed, perhaps the most important point to be learned from the book is that a serious consideration of the response of the heart to mechanical overload, ischemia, or excessive humoral stimuli must include evaluation of each of the topics in the table of contents. The heart responds to stress through alterations in both structure and function. How these changes are brought about is the subject of the initial chapters. These consider first the normal regulation of gene expression in the heart, the rapid response to mechanical overload that leads to both quantitative and qualitative changes in the contractile proteins, and our current understand ing of the signals that might be elicited by stress and alter gene expression. One chapter emphasizes the fact that, regardless of the nature of the stress, the common denominator is a discrepancy between energy requirements and expenditure. The central role of cellular acidosis in initiating the sequence of responses to stress and the possible roles of peptide regulators of transcription and protein regulators of translation are considered in detail.
Book Synopsis Autophagy: Biology and Diseases by : Zheng-Hong Qin
Download or read book Autophagy: Biology and Diseases written by Zheng-Hong Qin and published by Springer Nature. This book was released on 2019-11-27 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book series consists of 3 volumes covering the basic science (Volume 1), clinical science (Volume 2) and the technology and methodology (Volume 3) of autophagy. Volume 1 focuses on the biology of autophagy, including the signaling pathways, regulating processes and biological functions. Autophagy is a fundamental physiological process in eukaryotic cells. It not only regulates normal cellular homeostasis, and organ development and function, but also plays an important role in the pathogenesis of a wide range of human diseases. Thanks to the rapid development of molecular biology and omic technologies, research on autophagy has boomed in recent decades, and more and more cellular and animal models and state-of the-art technologies are being used to shed light on the complexity of signaling networks involved in the autophagic process. Further, its involvement in biological functions and the pathogenesis of various diseases has attracted increased attention around the globe. Presenting cutting-edge knowledge, this book series is a useful reference resource for researchers and clinicians who are working on or interested in autophagy.
Book Synopsis Membrane Biogenesis by : Jos A.F. Op den Kamp
Download or read book Membrane Biogenesis written by Jos A.F. Op den Kamp and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.
Book Synopsis Plant Programmed Cell Death by : Arunika N. Gunawardena
Download or read book Plant Programmed Cell Death written by Arunika N. Gunawardena and published by Springer. This book was released on 2015-10-08 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Programmed cell death (PCD) is a genetically encoded, active process which results in the death of individual cells, tissues, or whole organs. PCD plays an essential role in plant development and defense, and occurs throughout a plant’s lifecycle from the death of the embryonic suspensor to leaf and floral organ senescence. In plant biology, PCD is a relatively new research area, however, as its fundamental importance is further recognized, publications in the area are beginning to increase significantly. The field currently has few foundational reference books and there is a critical need for books that summarizes recent findings in this important area. This book contains chapters written by several of the world’s leading researchers in PCD. This book will be invaluable for PhD or graduate students, or for scientists and researchers entering the field. Established researchers will also find this timely work useful as an up-to-date overview of this fascinating research area.
Book Synopsis Cellular Migration and Formation of Neuronal Connections by :
Download or read book Cellular Migration and Formation of Neuronal Connections written by and published by Academic Press. This book was released on 2013-05-06 with total page 1081 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 2 offers 56 high level articles devoted mainly to Formation of Axons and Dendrites, Migration, Synaptogenesis, Developmental Sequences in the Maturation of Intrinsic and Synapse Driven Patterns. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 2 sections include coverage of mechanisms which regulate: the formation of axons and dendrites, cell migration, synapse formation and maintenance during development, and neural activity, from cell-intrinsic maturation to early correlated patterns of activity
Book Synopsis Non-Canonical Autophagy by : Giulia Petroni
Download or read book Non-Canonical Autophagy written by Giulia Petroni and published by Academic Press. This book was released on 2021-04-21 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between ‘canonical’ and ‘non-canonical’ forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of ‘non-canonical’ autophagy. The book discusses all forms of ‘non-canonical’ autophagy and the complexity of autophagy-dependent cell death. Readers will gain a better understanding of mechanisms underlying ‘non-canonical’ autophagy so that they can interpret the biological effects of autophagy correctly and identify reliable, novel and effective treatment strategies. Presents the most advanced information surrounding the molecular mechanisms underlying non-canonical autophagy Outlines the increasing evidence regarding the involvement of non-canonical autophagy in multiple physiological and pathological processes Discusses the therapeutic potential of autophagy modulators and the obstacles that have limited their development
Book Synopsis Dictyostelium by : Richard H. Kessin
Download or read book Dictyostelium written by Richard H. Kessin and published by Cambridge University Press. This book was released on 2001-01-11 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dictyostelia are soil amoebae capable of extraordinary feats of survival, motility, chemotaxis, and development. Characterised by their ability to transform from a single-celled organism into an elaborate assemblage of thousands of synchronously-moving cells, Dictyostelids are often referred to as 'social amoebae', and have been the subjects of serious study since the 1930s. Research in this area has been instrumental in understanding many problems in cellular biology. Beginning with the history of Dictyostelids and discussing each stage of their development, this book considers the evolution of this unique organism, analyses the special properties of the Dictyostelid genome, and presents in detail the methods available, at the time of the book's original publication in 2001, to manipulate their genes. Representing the synthesis of such material and with an emphasis on combining classical experiments with modern molecular findings, this book will be essential for researchers and graduates in developmental and cellular biology.
Book Synopsis Metabolic Cardiomyopathy by : H. Böhles
Download or read book Metabolic Cardiomyopathy written by H. Böhles and published by CRC Press. This book was released on 2004 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.
Download or read book Autophagy written by Nicholas Ktistakis and published by Humana Press. This book was released on 2019-01-05 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details a comprehensive and extensive set of protocols for the study of autophagy in vitro and in vivo. Chapters focus on mammals, various model organisms, and provide protocols for the study of autophagy-related processes outside of the canonical autophagy pathways. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Autophagy: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Download or read book Cell Death written by Gerry Melino and published by John Wiley & Sons. This book was released on 2010-02-22 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book on cell death contains 29 self-contained, peer-reviewed articles written by leading scientists in each field. It features overview articles aimed at undergraduates and non-specialists, which present basic information and provide entry into the following advanced articles. These advanced articles are written for postgraduate students and research workers, containing detailed information and key references allowing the reader to investigate a specific area in more depth. The book is an essential resource for educational purposes as well as a reference work for experienced researchers in the field. The articles will also be available electronically as part of the acclaimed Encyclopedia of Life Sciences (ELS). Key features: Provides a comprehensive overview on the research of programmed cell death. Edited by leaders in the field. Clearly written and illustrated articles. Full colour throughout. A spin-on to the acclaimed reference work, the Encyclopedia of Life Science (ELS). Combines introductory information with coverage of the latest discoveries in the field. Features overview level articles for advanced students or people new to a topic and more advanced articles for those requiring more detailed information. Serves as a reference work for advanced students as well as researchers in this field. Ideal library purchase for science, medical, and technology libraries in academia, government, and industry; medical libraries; networks and consortia covering these markets.
Download or read book Lysosomes written by H. Glaumann and published by . This book was released on 1987 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt:
