Au-Catalyzed Synthesis and Functionalization of Heterocycles

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Author :
Publisher : Springer
ISBN 13 : 3319351443
Total Pages : 289 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Au-Catalyzed Synthesis and Functionalization of Heterocycles by : Marco Bandini

Download or read book Au-Catalyzed Synthesis and Functionalization of Heterocycles written by Marco Bandini and published by Springer. This book was released on 2016-07-01 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal

Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, 2 Volumes

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119774152
Total Pages : 1209 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, 2 Volumes by : Tharmalingam Punniyamurthy

Download or read book Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, 2 Volumes written by Tharmalingam Punniyamurthy and published by John Wiley & Sons. This book was released on 2023-03-28 with total page 1209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transition-Metal-Catalyzed C-H Functionalization of Heterocycles A comprehensive guide to recent advances in this field Constituting the majority of all known compounds, heterocycles are structures that incorporate one or more heteroatoms within their core, thus exhibiting properties that are quite different from their all-carbon analogs. They are fundamental to all fields of chemistry and, therefore, their synthesis and modification has attracted a great deal of attention in the recent years. In this vein, transition-metal-catalyzed C-H bond functionalization forms a crucial tool for generating and analyzing heterocyclic compounds. Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume Set, showcases diverse C-H functionalization methodologies and their incorporation into the latest research. The chapters serve as an essential tool depicting detailed site-selective functionalization of heterocyclic cores, along with a comprehensive discussion on their mechanistic approaches. Readers of Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume-Set will also find: A detailed introduction to C-H activation along with the mechanistic aspects of transition-metal-catalyzed C-H bond activation reactions Easy-to-use structures with each chapter dedicated to a type of heterocycle and its specific functionalization methodologies A leading team of international authors in C-H bond functionalization Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume-Set is a valuable guide for students and researchers in organic synthesis and process development, in both academic and industrial contexts.

Heterocycles via Cross Dehydrogenative Coupling

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Author :
Publisher : Springer Nature
ISBN 13 : 9811391440
Total Pages : 494 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Heterocycles via Cross Dehydrogenative Coupling by : Ananya Srivastava

Download or read book Heterocycles via Cross Dehydrogenative Coupling written by Ananya Srivastava and published by Springer Nature. This book was released on 2019-08-23 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the developments in the synthesis and functionalization of different heterocycles based on the formation of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds using cross-dehydrogenative coupling (CDC). Consisting of 13 chapters, the book systematically describes the advances in the synthesis and functionalization of nitrogen, oxygen, and sulfur-containing heterocycles. It also discusses the various mechanistic pathways to help readers gain an in-depth understanding of the CDC reactions of heterocycles. Lastly, in order to promote green chemistry, it addresses a range of metal-free CDC reactions of heterocycles – an area that has attracted significant attention in both academic and industrial research.

Transition Metal-Catalyzed Heterocycle Synthesis via C-H Activation

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527338888
Total Pages : 596 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Transition Metal-Catalyzed Heterocycle Synthesis via C-H Activation by : Xiao-Feng Wu

Download or read book Transition Metal-Catalyzed Heterocycle Synthesis via C-H Activation written by Xiao-Feng Wu and published by John Wiley & Sons. This book was released on 2016-03-07 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting the tremendous growth of this hot topic in recent years, this book covers C-H activation with a focus on heterocycle synthesis. As such, the text provides general mechanistic aspects and gives a comprehensive overview of catalytic reactions in the presence of palladium, rhodium, ruthenium, copper, iron, cobalt, and iridium. The chapters are organized according to the transition metal used and sub-divided by type of heterocycle formed to enable quick access to the synthetic route needed. Chapters on carbonylative synthesis of heterocycles and the application of C-H activation methodology to the synthesis of natural products are also included. Written by an outstanding team of authors, this is a valuable reference for researchers in academia and industry working in the field of organic synthesis, catalysis, natural product synthesis, pharmaceutical chemistry, and crop protection.

Heterocycles from Double-Functionalized Arenes

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1782621369
Total Pages : 315 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Heterocycles from Double-Functionalized Arenes by : Xiao-Feng Wu

Download or read book Heterocycles from Double-Functionalized Arenes written by Xiao-Feng Wu and published by Royal Society of Chemistry. This book was released on 2015 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: The efficient synthesis of heterocycles has become one of the main branches in organic chemistry due to their use in the synthesis of natural products and pharmaceuticals. Current sythentic strategies based on C-H activation methodologies are met with many problems like harsh reaction conditions and low reaction efficiency. Double functionalized chemicals offer a perfect alternative for the synthesis of heterocycles. Heterocycles from Double-Functionalized Arenes starts with a short discussion on the importance of heterocycles and a brief introduction on the preparation of double-functionalized arenes. Specific chapters then look at five-membered heterocycles synthesis, six-membered heterocycles synthesis and macroheterocycles synthesis. This is the first book dedicated to the topic of transition metal catalyzed coupling reactions of double functionalized arenes in heterocycle synthesis and can be used as a handbook for senior researchers and as an introduction for organic chemistry students.

Synthesis and Modification of Heterocycles by Metal-Catalyzed Cross-coupling Reactions

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Author :
Publisher : Springer
ISBN 13 : 3319326104
Total Pages : 362 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Synthesis and Modification of Heterocycles by Metal-Catalyzed Cross-coupling Reactions by : Tamás Patonay

Download or read book Synthesis and Modification of Heterocycles by Metal-Catalyzed Cross-coupling Reactions written by Tamás Patonay and published by Springer. This book was released on 2016-06-15 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.

Multicomponent Reactions towards Heterocycles

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527349081
Total Pages : 626 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Multicomponent Reactions towards Heterocycles by : Erik Van der Eycken

Download or read book Multicomponent Reactions towards Heterocycles written by Erik Van der Eycken and published by John Wiley & Sons. This book was released on 2022-03-21 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a wide-ranging overview of essential topics and recent advances in MCR chemistry Heterocycles are a central component in natural product chemistry, pharmaceuticals, agrochemicals, and material science. New synthetic methodologies integrating the sequencing of multicomponent reactions (MCRs) are today being used for the rapid synthesis of diversified heterocycles in just one step. Multicomponent Reactions towards Heterocycles presents an up-to-date summary MCR chemistry with a focus on the conjugation between modern synthetic methodologies and MCRs. Featuring contributions by leaders in the field, this comprehensive resource highlights applications of MCRs in natural products and intermediate synthesis, discusses current trends and future prospects in MCR chemistry, outlines novel multicomponent procedures, and more. The authors provide the practical information required for designing new reaction strategies and mechanisms, covering topics including MCR-based green synthetic methods, cyclization and cycloaddition reactions, heterocycle multicomponent syntheses in a continuous flow, catalytic alkynoyl generation, MCR synthesis of saturated heterocycles, and C–H functionalization and multicomponent reactions. Provides a thorough overview of heterocycles as input in multicomponent reactions Discusses recent advances in the field of MCR chemistry and progress in the synthesis and functionalization of heterocycles Demonstrates the use of MCRs to simplify synthetic design and achieve complexity and diversity in novel bioactive molecules Highlights examples of multicomponent polymerizations, target-oriented synthesis, and applications of MCR in medicinal chemistry Explains the methodology of using on-resin MCRs to produce heterocycle compounds Illustrating the key role of MCRs towards heterocycles in natural product synthesis, drug discovery, organic synthesis, and other applications, Multicomponent Reactions towards Heterocycles is required reading for synthetic chemists in academia and industry alike.

Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, 2 Volumes

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Author :
Publisher : Wiley
ISBN 13 : 9781119774136
Total Pages : 0 pages
Book Rating : 4.7/5 (741 download)

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Book Synopsis Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, 2 Volumes by : Tharmalingam Punniyamurthy

Download or read book Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, 2 Volumes written by Tharmalingam Punniyamurthy and published by Wiley. This book was released on 2023-04-04 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transition-Metal-Catalyzed C-H Functionalization of Heterocycles A comprehensive guide to recent advances in this field Constituting the majority of all known compounds, heterocycles are structures that incorporate one or more heteroatoms within their core, thus exhibiting properties that are quite different from their all-carbon analogs. They are fundamental to all fields of chemistry and, therefore, their synthesis and modification has attracted a great deal of attention in the recent years. In this vein, transition-metal-catalyzed C-H bond functionalization forms a crucial tool for generating and analyzing heterocyclic compounds. Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume Set, showcases diverse C-H functionalization methodologies and their incorporation into the latest research. The chapters serve as an essential tool depicting detailed site-selective functionalization of heterocyclic cores, along with a comprehensive discussion on their mechanistic approaches. Readers of Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume-Set will also find: A detailed introduction to C-H activation along with the mechanistic aspects of transition-metal-catalyzed C-H bond activation reactions Easy-to-use structures with each chapter dedicated to a type of heterocycle and its specific functionalization methodologies A leading team of international authors in C-H bond functionalization Transition-Metal-Catalyzed C-H Functionalization of Heterocycles, Two-Volume-Set is a valuable guide for students and researchers in organic synthesis and process development, in both academic and industrial contexts.

Transition Metal-Catalyzed Couplings in Process Chemistry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527658920
Total Pages : 1 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Transition Metal-Catalyzed Couplings in Process Chemistry by : Javier Magano

Download or read book Transition Metal-Catalyzed Couplings in Process Chemistry written by Javier Magano and published by John Wiley & Sons. This book was released on 2013-07-03 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transition metal-catalyzed coupling reactions have a rich history that led to the awarding of the 2010 Nobel Prize in Chemistry to Professors Suzuki, Heck, and Negishi for their pioneering contributions to the field. The coming of age of this active area of research is showcased in this book through case studies in which process chemists from the pharmaceutical industry share their personal experiences developing their own transition metal-catalyzed couplings for the large-scale manufacture of active pharmaceutical ingredients. Authors from Pfizer, Merck, Boehringer-Ingelheim, Novartis, Amgen, GSK, AstraZeneca, and other companies describe the evolution of robust coupling processes from inception through early and late development, including commercial routes where applicable. This book covers a wide range of coupling transformations while capturing the lessons learned from each process. Every case study details the optimization of at least one transition metal-catalyzed coupling while elaborating on issues such as design of experiments, scalability and throughput, product purification, process safety, and waste management. The important issue of metal removal and the different technologies available to accomplish this goal are also addressed. Finally, a section covers novel technologies for cross-coupling with high potential for future applications on a large scale, such as microwave and flow chemistry as well as green cross-couplings performed in water. With Forewords by Stephen L. Buchwald, Massachusetts Institute of Technology, Trevor Laird, Editor of Organic Process Research and Development and Neal G. Anderson, Anderson's Process Solutions LLC.

Synthesis of Heterocycles via Metal-Catalyzed Reactions that Generate One or More Carbon-Heteroatom Bonds

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Author :
Publisher : Springer
ISBN 13 : 3642388809
Total Pages : 276 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Synthesis of Heterocycles via Metal-Catalyzed Reactions that Generate One or More Carbon-Heteroatom Bonds by : John P. Wolfe

Download or read book Synthesis of Heterocycles via Metal-Catalyzed Reactions that Generate One or More Carbon-Heteroatom Bonds written by John P. Wolfe and published by Springer. This book was released on 2013-09-11 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Saturated Heterocycles via Metal-Catalyzed Alkene Carboamination or Carboalkoxylation Reactions, by John P. Wolfe Synthesis of Saturated Heterocycles via Metal-Catalyzed Alkene Diamination, Aminoalkoxylation, or Dialkoxylation Reactions, by Sherry R. Chemler Synthesis of Heterocycles via Metal-Catalyzed Wacker-Type Oxidative Cyclization Reactions of Alkoxy- or Amino-Alkenes, by Wanbin Zhang Synthesis of Saturated Heterocycles via Metal-Catalyzed Hydroamination or Hydroalkoxylation Reactions, by Lisa D. Julian Synthesis of Saturated Heterocycles via Metal-Catalyzed Allylic Alkylation Reactions, by Aaron Aponick Synthesis of Heterocycles via Metal-Catalyzed Cascade/Domino Reactions that Generate a C–N or C–O Bond, by Mark Lautens Synthesis of Saturated Heterocycles via Metal-Catalyzed Formal Cycloaddition Reactions that Generate a C–N or C–O Bond, by Jerome Waser

Advances in Cross-Coupling Reactions

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Author :
Publisher : MDPI
ISBN 13 : 3039435671
Total Pages : 234 pages
Book Rating : 4.0/5 (394 download)

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Book Synopsis Advances in Cross-Coupling Reactions by : José Pérez Sestelo

Download or read book Advances in Cross-Coupling Reactions written by José Pérez Sestelo and published by MDPI. This book was released on 2020-12-03 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this Special Issue, recent advances in cross-coupling reactions are presented in the form of original research articles, reviews, and short communications. These contributions cover different topics in this area, including novel coupling reactions, reaction conditions, synthetic alternatives, metal ligands, and applications for new pharmaceutical compounds and organic materials. In particular, the reviews deal with methodologies such as the synthesis of diarylketones through palladium catalysis and the most relevant examples of Suzuki–Miyaura and Buchwald–Hartwig coupling reactions in the synthesis of bioactive compounds. The synthetic utility of cross-coupling reactions for the synthesis of medium-size rings and the utility of Stille and Suzuki coupling reactions for the synthesis of new molecular machines based on sterically hindered anthracenyl trypticenyl units are also summarized. The original research articles present the synthesis of 2-alkynylpyrrols by inverse Sonogashira coupling and the synthesis of indoles under oxidative dearomative cross-dehydrogenative conditions. The efficient combination of iridium-catalyzed C–H borylation of aryl halides with the Sonogashira coupling and a sequential iridium-catalyzed borylation of NH-free pyrroles followed by a Suzuki–Miyaura reaction are included. The synthesis of aryl propionic acids, a common structural motif in medicinal chemistry, and the synthesis of new organic dyes are also covered.

Catalysis & Photocatalysis Editor’s Pick 2021

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889667863
Total Pages : 163 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Catalysis & Photocatalysis Editor’s Pick 2021 by : Bunsho Ohtani

Download or read book Catalysis & Photocatalysis Editor’s Pick 2021 written by Bunsho Ohtani and published by Frontiers Media SA. This book was released on 2021-05-20 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Heterocyclic Chemistry

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Author :
Publisher : Academic Press
ISBN 13 : 0128155388
Total Pages : 274 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Advances in Heterocyclic Chemistry by :

Download or read book Advances in Heterocyclic Chemistry written by and published by Academic Press. This book was released on 2018-05-21 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Heterocyclic Chemistry, Volume 126, is the definitive series in the field, one that is of great importance to organic chemists, polymer chemists and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature is used more frequently in explanations. Updates to this release include sections on The Literature of Heterocyclic Chemistry, Part XVI, 2016, The preparation and properties of heteroarylazulenes and hetero-fused azulenes, Recent developments in pyrazole chemistry, Yne, Ene-Yne Synthetic Approaches to Heterocycles, Appel Salt and Heterocycles: A review of Thirty Years of 4,5-Dichloro-1,2,3-dithiazolium Chloride Chemistry, and more. Written by established authorities in the field, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists Provides timely, comprehensive reviews written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds

Amino Acids: Insights and Roles in Heterocyclic Chemistry

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Author :
Publisher : CRC Press
ISBN 13 : 1000738922
Total Pages : 420 pages
Book Rating : 4.0/5 (7 download)

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Book Synopsis Amino Acids: Insights and Roles in Heterocyclic Chemistry by : Zerong Wang

Download or read book Amino Acids: Insights and Roles in Heterocyclic Chemistry written by Zerong Wang and published by CRC Press. This book was released on 2023-05-26 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second volume of a first-of-its-kind four-volume book set that provides readers with up-to-date information on α-amino acids, the potential challenges in working with α-amino acids, the protecting groups for the carboxyl, amino and side chain groups of the amino acids, and the most popular heterocyclic compounds that are originating from alpha-amino acids. These heterocyclic compounds include hydantoins, thiohydantoins (including 2-thiohydantoins, 4-thiohydantoins, 2,4-dithiohydantoins), 2,5-diketopiperazines, N-carboxyanhydrides, N-thiocarboxyanhydrides, sydnones, sydnonimines, azlactones, pseudoazlactones, and oxazolidin-5-ones. This is the first resource to comprehensively collect all the heterocycles that can be directly prepared from α-amino acids. In addition, almost all kinds of synthetic methods for a particular type of heterocycles from alpha-amino acids are included, along with the detailed mechanistic discussions and experimental procedures. In Volume 2: Hydantoins, Thiohydantoins, and 2,5-Diketopiperazines compiles the three IUPAC accepted nomenclature systems for heterocyclic compounds, which will be very useful for readers working in the heterocyclic chemistry field for giving synthesized molecules their correct names. In addition, three groups of heterocyclic compounds, i.e., hydantoins, thiohydantoins (including 2-thiohydantoin, 4-thiohydantoin and 2,4-dithiohydantoin), and 2,5-diketopiperazines, have been organized with updated literature information. Particularly, all three groups of heterocyclic compounds have demonstrated many important biological activities, particularly anticancer and antibacterial activities. On the other hand, these three groups of heterocycles can be applied as substrates to make other chemical derivatives, particularly novel unnatural amino acids. All their reactivities have been compiled and updated. The other volumes include: Volume 1: Protecting Groups Volume 3: N-Carboxyanhydrides, N-Thiocarboxyanhydrides, and Sydnones Volume 4: Azlactones and Oxazolidin-5-ones All together, this unique 4-volume set thoroughly covers the two types of heterocyclic compounds that are originated from alpha-amino acids, providing carefully compiled updated information with detailed examples. The author has shared many thoughtful insights based on his strong background in physical organic chemistry. The volumes will be highly valuable for graduate students and senior students, as well as for professors and researchers working in the field of medicinal and pharmaceutical chemistry, organic chemistry, organic synthesis, heterocycles, and proteins and peptides.

Non-Metal Catalyzed Synthesis

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Author :
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110986167
Total Pages : 509 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Non-Metal Catalyzed Synthesis by : Yunfei Du

Download or read book Non-Metal Catalyzed Synthesis written by Yunfei Du and published by Walter de Gruyter GmbH & Co KG. This book was released on 2023-12-04 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Heterocycles from Transition Metal Catalysis

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Author :
Publisher : Springer
ISBN 13 : 9789048103973
Total Pages : 200 pages
Book Rating : 4.1/5 (39 download)

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Book Synopsis Heterocycles from Transition Metal Catalysis by : András Kotschy

Download or read book Heterocycles from Transition Metal Catalysis written by András Kotschy and published by Springer. This book was released on 2009-09-03 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Heterocycles from Transition Metal Catalysis: Formation and Functionalization" provides a concise summary of the prominent role of late transition metal (palladium, nickel, copper) catalysed processes in the synthesis and functionalization of heterocyclic systems. It gives an introduction to catalytic transformations, an overview of the most important reaction types, and presents synthetically useful catalytic processes classified by the target system and the type of transformation. The book provides a representative selection of transition metal catalysed reactions transformations that are relevant in heterocyclic chemistry. In this way, the authors present a useful resource for members of the academic community looking for a textbook as well as industrial chemists in search of a reference book. This book will be an invaluable resource for synthetic chemists, medicinal chemists, and those more generally interested in applied catalysis.

Synthesis of Heterocycles via Cycloadditions II

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Author :
Publisher : Springer
ISBN 13 : 3540783733
Total Pages : 214 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Synthesis of Heterocycles via Cycloadditions II by : Alfred Hassner

Download or read book Synthesis of Heterocycles via Cycloadditions II written by Alfred Hassner and published by Springer. This book was released on 2008-04-10 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: See Table of Contents (PMP)