Assap 94

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The Enzyme Reference

Author : Daniel L. Purich
Publisher : Elsevier
ISBN 13 : 0080550819
Total Pages : 940 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Enzyme Reference by : Daniel L. Purich

Download or read book The Enzyme Reference written by Daniel L. Purich and published by Elsevier. This book was released on 2003-01-04 with total page 940 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this work is to provide a fuller spectrum of information in a single source on enzyme-catalyzed reactions than is currently available in any published reference work or as part of any Internet database. The Enzyme Reference: A Comprehensive Guidebook to Enzyme Nomenclature, Reactions, and Methods includes 20,000 review articles and seminal research papers. Additionally, it provides a novel treatment of so-called ATPase and GTPase reactions to account for the noncovalent substratelike and productlike states of molecular motors, elongation factors, transporters, DNA helicases, G-reulatory proteins, and other energases. - Includes a compendium of over 6,000 enzyme reactions (including enzyme commission numbers, alternative names, substrates, products, alternative substrates, and properties) - Covers over 900 chemical structures of key metabolites and cofactors - Index directs readers to the exact pages for over 9,500 enzyme names

ASSAP '94

Author : Peter Cappello
Publisher :
ISBN 13 :
Total Pages : 450 pages
Book Rating : 4.:/5 (118 download)

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Book Synopsis ASSAP '94 by : Peter Cappello

Download or read book ASSAP '94 written by Peter Cappello and published by . This book was released on 1994 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Treatise on the Assaying of Lead, Copper, Silver, Gold, and Mercury

Author : Theodor Bodemann
Publisher :
ISBN 13 :
Total Pages : 234 pages
Book Rating : 4.M/5 ( download)

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Book Synopsis A Treatise on the Assaying of Lead, Copper, Silver, Gold, and Mercury by : Theodor Bodemann

Download or read book A Treatise on the Assaying of Lead, Copper, Silver, Gold, and Mercury written by Theodor Bodemann and published by . This book was released on 1878 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:

High Throughput Screening

Author : William P. Janzen
Publisher : Springer Science & Business Media
ISBN 13 : 1592591809
Total Pages : 269 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis High Throughput Screening by : William P. Janzen

Download or read book High Throughput Screening written by William P. Janzen and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: In High Throughput Screening, leading scientists and researchers expert in molecular discovery explain the diverse technologies and key techniques used in HTS and demonstrate how they can be applied generically. Writing to create precisely the introductory guidebook they wish had been available when they started in HTS, these expert seasoned authors illuminate the HTS process with richly detailed tutorials on the biological techniques involved, the management of compound libraries, and the automation and engineering approaches needed. Extensive discussions provide readers with all those key elements of pharmacology, molecular biology, enzymology, and biochemistry that will ensure the identification of suitable targets and screens, and detail the technology necessary to mine millions of data points for meaningful knowledge.

Water-supply Paper

Author :
Publisher :
ISBN 13 :
Total Pages : 678 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Water-supply Paper by :

Download or read book Water-supply Paper written by and published by . This book was released on 1918 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Integrins

Author :
Publisher : Elsevier
ISBN 13 : 0080551386
Total Pages : 613 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Integrins by :

Download or read book Integrins written by and published by Elsevier. This book was released on 2007-08-27 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrin, or integrin receptor, is an integral membrane protein in the plasma membrane of cells. It plays a role in the attachment of a cell to the extracellular matrix (ECM) and to other cells, and in signal transduction from the ECM to the cell. There are many types of integrin, and many cells have multiple types on their surface. Integrins are of vital importance to all metazoans, from humans to sponges. This volume in Methods in Enzymology presents methods for studying integrins.

Pharmaceutical Bioassays

Author : Shiqi Peng
Publisher : John Wiley & Sons
ISBN 13 : 0470227605
Total Pages : 525 pages
Book Rating : 4.4/5 (72 download)

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Book Synopsis Pharmaceutical Bioassays by : Shiqi Peng

Download or read book Pharmaceutical Bioassays written by Shiqi Peng and published by John Wiley & Sons. This book was released on 2009-11-09 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive compendium of bioassay procedures and applications A virtual encyclopedia of key bioassay protocols, this up-to-date, essential resource reviews the methods and applications of bioassays that quantify drug activity and evaluate the validity of pharmacological models. Demonstrating the specific ways in which various pharmaceutical bioassays interpret the activity of drug molecules, the book covers the evaluation and screening of drug compounds in a wide spectrum of therapeutic categories. Throughout, the authors use various models to link experimental observations with findings that clarify the effect of drug compounds on cellular biology and measure the pharmacological activity of chemical substances. This provides an important technological platform for successful drug research and clinical therapy, making Pharmaceutical Bioassays an ideal sourcebook for pharmacologists, pharmaceutical and medical researchers, analytical chemists, toxicologists, and students. Just as a fundamental knowledge of pharmaceutical bioassays is vital to understanding how bioactive agents and new drugs are defined, discovered, and developed, so too is this indispensable reference, which: Offers a complete reference on pharmaceutical bioassays and their specific applications in the assessment of therapies for cancer, Alzheimer’s, diabetes, epilepsy, inflammation, antimalarials, pharmacogenomics, and other major therapeutic areas Covers bioassays that measure toxicity, including those for chemical toxicity and hepatoxicity—a particularly significant consideration in the development of safe and tolerable medications Highlights clinically relevant methods, ideas, and techniques to support any pharmaceutical researcher Suggests guidelines and systems to enhance communication between pharmacologists, chemists, and biologists Provides an informative analysis of pharmaceutical bioassay technologies and lab applications

Oxidative Stability and Shelf Life of Foods Containing Oils and Fats

Author : Min Hu
Publisher : Elsevier
ISBN 13 : 163067057X
Total Pages : 582 pages
Book Rating : 4.6/5 (36 download)

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Book Synopsis Oxidative Stability and Shelf Life of Foods Containing Oils and Fats by : Min Hu

Download or read book Oxidative Stability and Shelf Life of Foods Containing Oils and Fats written by Min Hu and published by Elsevier. This book was released on 2016-01-19 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative Stability and Shelf Life of Foods Containing Oils and Fats focuses on food stability and shelf life, both important factors in the improvement and development of food products. This book, relevant for professionals in the food and pet food industries, presents an evaluation of methods for studies on the oxidative stability and shelf life of bulk oils/fats, fried oils and foods, food emulsions, dried foods, meat and meat products, and seafood in food and pet food. - Focuses on the application of various evaluation methods to studies of oxidative stability and shelf life in oils and fats and oils and fats-containing foods in the food and pet food industries - Discusses oxidative stability and shelf life of low-moisture (dry) food, including dry pet food - Discusses lipid co-oxidation with protein because a number of food products contain both lipids and proteins - Directed mainly toward readers working in the food and pet food industries

Biennial Review of Infertility

Author : Catherine Racowsky
Publisher : Springer Science & Business Media
ISBN 13 : 1441984569
Total Pages : 296 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Biennial Review of Infertility by : Catherine Racowsky

Download or read book Biennial Review of Infertility written by Catherine Racowsky and published by Springer Science & Business Media. This book was released on 2011-06-07 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this second volume, the Biennial Review of Infertility brings together the most up-to-date research and clinical information on male and female infertility, emerging assisted reproductive techniques, and controversial issues in reproductive medicine. This volume includes discussion of cutting-edge topics such as epigenetics, proteomics, and the role of the environment in fertility, as well as insightful evidence-based discussion of common clinical procedures. It is the cumulative effort of a preeminent panel of experts presenting each chapter in a clear and well-balanced manner. Created to provide an ongoing appraisal of current knowledge, the Biennial Review of Infertility stimulates communication amongst all those working to help couples resolve their infertility.

Protein Tyrosine Phosphatases

Author : Damien Thévenin
Publisher : Springer Nature
ISBN 13 : 1071635697
Total Pages : 321 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Protein Tyrosine Phosphatases by : Damien Thévenin

Download or read book Protein Tyrosine Phosphatases written by Damien Thévenin and published by Springer Nature. This book was released on 2024-01-27 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition volume expands on the previous edition with discussions on the latest advancements in protein tyrosine phosphatases (PTP) research used to investigate these essential enzymes and new inhibitors. The new techniques covered in the chapters of this book include studying enzymes in vitro, in cells, and in animal models through proteomics, genomics, and structural biology. Furthermore, new advances in pharmacology and drug design have contributed to the developing novel therapeutics that target PTPs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Protein Tyrosine Phosphatases: Methods and Protocols, Second Edition is a valuable resource for both experienced and novel researchers in this field, and will lead to discoveries and accelerated progress in the field of PTP, signal transduction, and drug development.

Laboratory Instructions in Assaying and Practical Chemistry

Author : James Park
Publisher :
ISBN 13 :
Total Pages : 234 pages
Book Rating : 4.:/5 (6 download)

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Book Synopsis Laboratory Instructions in Assaying and Practical Chemistry by : James Park

Download or read book Laboratory Instructions in Assaying and Practical Chemistry written by James Park and published by . This book was released on 1896 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Art of Process Chemistry

Author : Nobuyoshi Yasuda
Publisher : John Wiley & Sons
ISBN 13 : 3527633588
Total Pages : 275 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis The Art of Process Chemistry by : Nobuyoshi Yasuda

Download or read book The Art of Process Chemistry written by Nobuyoshi Yasuda and published by John Wiley & Sons. This book was released on 2010-12-01 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing must-have knowledge for the pharmaceutical industry and process chemists in industry, this ready reference offers solutions for saving time and money and supplying -- in a sustainable way -- valuable products. Application-oriented and well structured, each chapter presents successful strategies for the latest modern drugs, showing how to provide very fast bulk quantities of drug candidates. Throughout, the text illustrates how all the key factors are interwoven and dependent on one another in creating optimized methods for optimal products.

Current Concepts in Drug Metabolism and Toxicology

Author : Gabrielle M. Hawksworth
Publisher : Academic Press
ISBN 13 : 0123983398
Total Pages : 302 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Current Concepts in Drug Metabolism and Toxicology by : Gabrielle M. Hawksworth

Download or read book Current Concepts in Drug Metabolism and Toxicology written by Gabrielle M. Hawksworth and published by Academic Press. This book was released on 2012-06-12 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Advances in Pharmacology explores the current concepts in drug metabolism and toxicology. Chapters cover the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike. Explores the current concepts in drug metabolism and toxicology Chapters cover such areas as the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity An essential resource for pharmacologists, immunologists and biochemists alike

Public Health and Toxicology Issues in Drug Research, Volume 2

Author : Rakesh Kumar Tekade
Publisher : Elsevier
ISBN 13 : 0443158436
Total Pages : 854 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Public Health and Toxicology Issues in Drug Research, Volume 2 by : Rakesh Kumar Tekade

Download or read book Public Health and Toxicology Issues in Drug Research, Volume 2 written by Rakesh Kumar Tekade and published by Elsevier. This book was released on 2024-03-26 with total page 854 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicodynamics in Drug Research, Volume 2: Public Health and Toxicology Issues examines the implications of public health issues and the impact of pharmaceuticals, chemical and food toxicants, dietary phytochemicals, and medical treatments on human health. Volume 2: Public Health and Toxicology Issues in Drug Research: Toxicity and Toxicodynamics covers topics on pharmacokinetics and toxicokinetics such as population pharmacokinetics/toxicokinetics, the design of toxicokinetic studies, and the use of toxicokinetic data in preclinical safety assessments. The book investigates the health effect caused by the bioaccumulation of pharmaceutical and personal care products and the impact of drug-induced toxicity on different systems of the body. It discusses the mechanistic pathways of food toxicants and illustrates the molecular mechanisms of the chemopreventive role of dietary phytochemicals. It also delves into the toxic effects of medical treatments and materials. Ethical, legal, societal, and professional issues in toxicology round off the coverage providing a valuable resource to interested in learning more about the health impact and public health issues related to the toxicity of pharmaceuticals, dietary supplements, personal care products, and medical treatments. - Discusses the impact of pharmaceuticals, food, and chemical toxicants on human health - Examines the toxic effects of medical treatments, clinical administrations, and materials - Explores public health issues around drug safety and toxicology

Histone Methyltransferases

Author : Raphaël Margueron
Publisher : Springer Nature
ISBN 13 : 1071624814
Total Pages : 490 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Histone Methyltransferases by : Raphaël Margueron

Download or read book Histone Methyltransferases written by Raphaël Margueron and published by Springer Nature. This book was released on 2022-06-22 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides methods used to investigate histone methyltransferase function. Chapters guide readers through a comprehensive set of approaches that detail phylogenetic diversity, histone demethylase activities in vitro, generating chromatin substrates, auto-methylation, quantification of metabolites, protein purification, crystallization, X-ray structure, cryogenic electron microscopy, assessing genome-wide patterns, CUT&Tag in mouse embryonic tissues, chemical biology approaches, peptide SPOT arrays, nascent chromatin capture, ectopic protein tethering, computational models, and development of methyltransferase inhibitors. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Histone Methyltransferases: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.

Urologic Oncology

Author : Timothy L. Ratliff
Publisher : Springer Science & Business Media
ISBN 13 : 1461328438
Total Pages : 369 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Urologic Oncology by : Timothy L. Ratliff

Download or read book Urologic Oncology written by Timothy L. Ratliff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of genitourinary tumors is an area of recent rapid growth both in the understanding of disease processes and in the development of new diagnostic and therapeutic modalities. During rapid growth phases within any field, it is desirable to reflect on the current 'state of the art'. It is difficult even for experts in reputed areas of advancement to distinguish true advances from false leads, but it is far more difficult yet for those whose expertise lies in other areas to evaluate important advances. Thus, an objective assessment of evolving areas of investigation in the form of a comprehensive review is of considerable value. we have attempted to provide the reader with an over In this volume, view of some of the current areas of investigation in urologic oncology by experts in each area. There often is a tendency for invited papers in books of this nature to lack important critical peer review and therefore, suffer from a lack of objectivity. We have attempted to diminish this problem by the selection of two experts to discuss each subject. We believe that this format has improved the overall quality of the book for two reasons: 1) the know ledge of each contributor that his or her work would be reviewed by a peer 2) the fact that contributions by encourages more rigorous scholarship, and two experts, including the individual insights of each, provides a better per spective for the reader.

Neoplastic Transformation in Human Cell Culture

Author : Johng S. Rhim
Publisher : Springer Science & Business Media
ISBN 13 : 1461204119
Total Pages : 405 pages
Book Rating : 4.4/5 (612 download)

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Book Synopsis Neoplastic Transformation in Human Cell Culture by : Johng S. Rhim

Download or read book Neoplastic Transformation in Human Cell Culture written by Johng S. Rhim and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of carcinogenic agents in the deveolopment of human cancers is now being defined using a variety of human cells as experi mental model systems. A workshop on "neoplastic transformation in human cell systems in vitro: mechanisms of carcinogenesis" was held at the Georgetown University Medical Center, Washington, DC, on April 25-26, 1991. The aims of the workshop were to present the state-of-the art in the transformation of human cells in culture, as well as to provide insight into the molecular and cellular changes involved in the conver sion of normal cells to a neoplastic state of growth. The following topics were closely related to the theme of the workshops: 1. Derivation of in vitro model systems (epithelial, fibroblastic, and hematopoietic). 2. Factors modulating cellular transformation. 3. Usefulness of defined in vitro model systems for viral, chemical, and radiation carcinogenesis. 4. Multistep nature of human cell carcinogenesis. 5. Role of activated and suppressor oncogenes in neoplastic trans formation. The workshop was organized by J. S. Rhim and A. Dritschilo (cochairmen), G. Jay, J. little, M. McCormick, R Tennant, and R R Weischelbaum. There were 32 speakers, 30 poster presentations, and about 190 participants.