Aspects Of Store Operated Calcium Entry In Skeletal Muscle Myotubes

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Store-Operated Calcium Channels

Author :
Publisher : Academic Press
ISBN 13 : 0124079385
Total Pages : 307 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Store-Operated Calcium Channels by :

Download or read book Store-Operated Calcium Channels written by and published by Academic Press. This book was released on 2013-07-24 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. - The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels - Contributors are authoritative researchers who have produced important advances in the field - The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject

Mammalian Transient Receptor Potential (TRP) Cation Channels

Author : Bernd Nilius
Publisher : Springer
ISBN 13 : 331905161X
Total Pages : 569 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Mammalian Transient Receptor Potential (TRP) Cation Channels by : Bernd Nilius

Download or read book Mammalian Transient Receptor Potential (TRP) Cation Channels written by Bernd Nilius and published by Springer. This book was released on 2014-06-24 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.

Store-operated Ca2+ entry (SOCE) pathways

Author : Klaus Groschner
Publisher : Springer Science & Business Media
ISBN 13 : 3709109620
Total Pages : 485 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Store-operated Ca2+ entry (SOCE) pathways by : Klaus Groschner

Download or read book Store-operated Ca2+ entry (SOCE) pathways written by Klaus Groschner and published by Springer Science & Business Media. This book was released on 2012-04-23 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Store-operated Ca2+ entry (SOCE) serves to control essential functions throughout the human body and represents a novel and attractive target for therapeutic intervention. This book provides an extensive overview of the role of SOCE pathways in Molecular Physiology and Cell Biology, as well as their clinical significance. (Patho)physiological principles and emerging therapeutic strategies are delineated in a way that is valuable both for the education of graduate students in advanced Cell Biology/Molecular Physiology and for the promotion of innovative research and developments in the clinical/therapeutic fields. A comprehensive, clear and elaborate representation of current concepts is provided, including a pathophysiological section arranged in a tissue/organ/system-oriented manner. The book is intended for basic researchers specializing in cell signaling, ion transport, or pharmacology, as well as biomedical scientists and clinicians with a focus on immunology, neurology or cardiology.

Molecular Components of Store-Operated Calcium Entry in Health and Disease

Author : Joanna Gruszczynska-Biegala
Publisher : Frontiers Media SA
ISBN 13 : 2889717569
Total Pages : 199 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Molecular Components of Store-Operated Calcium Entry in Health and Disease by : Joanna Gruszczynska-Biegala

Download or read book Molecular Components of Store-Operated Calcium Entry in Health and Disease written by Joanna Gruszczynska-Biegala and published by Frontiers Media SA. This book was released on 2021-12-01 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt:

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

Author : Wolfgang B. Liedtke, MD, PH.D.
Publisher : CRC Press
ISBN 13 : 1420005847
Total Pages : 502 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades by : Wolfgang B. Liedtke, MD, PH.D.

Download or read book TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades written by Wolfgang B. Liedtke, MD, PH.D. and published by CRC Press. This book was released on 2006-09-29 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st

Disorders of Voluntary Muscle

Author : George Karpati
Publisher : Cambridge University Press
ISBN 13 : 9780521650625
Total Pages : 800 pages
Book Rating : 4.6/5 (56 download)

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Book Synopsis Disorders of Voluntary Muscle by : George Karpati

Download or read book Disorders of Voluntary Muscle written by George Karpati and published by Cambridge University Press. This book was released on 2001-07-12 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rewritten and redesigned, this remains the one essential text on the diseases of skeletal muscle.

Muscle 2-Volume Set

Author : Joseph Hill
Publisher : Academic Press
ISBN 13 : 0123815118
Total Pages : 1468 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Muscle 2-Volume Set by : Joseph Hill

Download or read book Muscle 2-Volume Set written by Joseph Hill and published by Academic Press. This book was released on 2012-08-29 with total page 1468 pages. Available in PDF, EPUB and Kindle. Book excerpt: A valuable study of the science behind the medicine, Muscle: Fundamental Biology and Mechanisms of Disease brings together key leaders in muscle biology. These experts provide state-of-the-art insights into the three forms of muscle--cardiac, skeletal, and smooth--from molecular anatomy, basic physiology, disease mechanisms, and targets of therapy. Commonalities and contrasts among these three tissue types are highlighted. This book focuses primarily on the biology of the myocyte. Individuals active in muscle investigation--as well as those new to the field--will find this work useful, as will students of muscle biology. In the case of hte former, many wish to grasp issues at the margins of their own expertise (e.g. clinical matters at one end; molecular matters at the other), adn this book is designed to assist them. Students, postdoctoral fellows, course directors and other faculty will find this book of interest. Beyond this, many clinicians in training (e.g. cardiology fellows) will benefit. - The only resource to focus on science before the clinical work and therapeutics - Tiered approach to subject: discussion first of normal muscle function through pathological/disease state changes, and ending each section with therapeutic interventions - Coverage of topics ranging from basic physiology to newly discovered molecular mechanisms of muscle diseases for all three muscle types: cardiac, skeletal, and smooth

Calcium Signaling

Author : Md. Shahidul Islam
Publisher : Springer Nature
ISBN 13 : 3030124576
Total Pages : 1103 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Calcium Signaling by : Md. Shahidul Islam

Download or read book Calcium Signaling written by Md. Shahidul Islam and published by Springer Nature. This book was released on 2019-10-23 with total page 1103 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Issues in Biophysics and Geophysics Research and Application: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1490106103
Total Pages : 1160 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis Issues in Biophysics and Geophysics Research and Application: 2013 Edition by :

Download or read book Issues in Biophysics and Geophysics Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 1160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Biophysics and Geophysics Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Geophysics. The editors have built Issues in Biophysics and Geophysics Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Geophysics in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biophysics and Geophysics Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Proteins of Excitable Membranes

Author : Bertil Hille
Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 360 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Proteins of Excitable Membranes by : Bertil Hille

Download or read book Proteins of Excitable Membranes written by Bertil Hille and published by Wiley-Interscience. This book was released on 1987 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a core of experts, this compilation of articles brings together the latest information on the membrane function and structure of excitable proteins. Topics include kinetic analysis of channel gating and pump cycling, agonist actions of drugs and toxins, electron microscope and x-ray image reconstruction, protein purification and functional reconstruction, subunit assembly, and cloning of the genetic message. It investigates how membrane functions are being dissected and explained by combined functional, structural, and chemical approaches.

Calcium Homeostasis in Skeletal Muscle Function, Plasticity and Disease

Author : Matias Mosqueira
Publisher : Frontiers Media SA
ISBN 13 : 2889668169
Total Pages : 171 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Calcium Homeostasis in Skeletal Muscle Function, Plasticity and Disease by : Matias Mosqueira

Download or read book Calcium Homeostasis in Skeletal Muscle Function, Plasticity and Disease written by Matias Mosqueira and published by Frontiers Media SA. This book was released on 2021-05-28 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Clinical Nutrition and Aging

Author : Chad Cox
Publisher : CRC Press
ISBN 13 : 1315361957
Total Pages : 307 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Clinical Nutrition and Aging by : Chad Cox

Download or read book Clinical Nutrition and Aging written by Chad Cox and published by CRC Press. This book was released on 2017-10-02 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title includes a number of Open Access chapters. Sarcopenia—the loss of muscle mass and strength that occurs with advancing age—is a major health challenge, particularly in North America, Europe, and Japan, which have large aging populations. This compendium volume is a valuable addition to the existing literature, providing state-of-the-art information on the most effective prevention and treatment options. Included are research articles on nutrition management and the prevention of sarcopenia; protein therapy for sarcopenia; effect of exercise on sarcopenia; and other therapeutic strategies, including antioxidants and steroids.

Challenges and Opportunities of Targeting Muscle for Therapy

Author : Carlo Rinaldi
Publisher : Frontiers Media SA
ISBN 13 : 2889747840
Total Pages : 128 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Challenges and Opportunities of Targeting Muscle for Therapy by : Carlo Rinaldi

Download or read book Challenges and Opportunities of Targeting Muscle for Therapy written by Carlo Rinaldi and published by Frontiers Media SA. This book was released on 2022-03-30 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Index Medicus

Author :
Publisher :
ISBN 13 :
Total Pages : 2164 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2164 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Thermoregulation Part II

Author :
Publisher : Elsevier
ISBN 13 : 0444640754
Total Pages : 452 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Thermoregulation Part II by :

Download or read book Thermoregulation Part II written by and published by Elsevier. This book was released on 2018-11-17 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thermoregulation, Part II: From Basic Neuroscience to Clinical Neurology, Volume 155, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function. In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions. - Presents a clear, logical pathway from the fundamental physiology of thermoregulation, through neurobiology, to clinical applications and disease - Enables researchers and clinicians to better understand the value of temperature measurement in disease and the use of temperature as a therapy - Integrates content from a broad field of research, including topics on the molecular physiology of temperature receptors, to the management of accidental hypothermia

Calcium Entry Pathways in Non-excitable Cells

Author : Juan A. Rosado
Publisher : Springer
ISBN 13 : 3319269747
Total Pages : 469 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Calcium Entry Pathways in Non-excitable Cells by : Juan A. Rosado

Download or read book Calcium Entry Pathways in Non-excitable Cells written by Juan A. Rosado and published by Springer. This book was released on 2016-05-09 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium entry pathways in non-excitable cells presents a concise synthesis of thoughtfully selected topics covering from the different calcium entry mechanisms in non-excitable cells to the cellular microdomains and organelles regulating the calcium entry process. Particular attention is given to the fascinating group of ion channels involved in different calcium entry pathways as well as the emerging role of these channels in human disease. Calcium entry is an essential mechanism for cellular function in non-excitable cells. In general, two main calcium entry pathways exist in non-excitable cells: one pathway, named store-operated calcium entry (SOCE) requires store depletion and the second pathway is regulated by receptor occupation, but independently on calcium store depletion. The search for the molecular components of calcium entry has identified the stromal interaction molecule 1 (STIM1), as the calcium sensor of the intracellular calcium stores, and Orai as well as TRP channels as the calcium-permeable channels located in the plasma membrane. The location, interactions and function of these channels are finely regulated by a number of scaffolding proteins, membrane microdomains and cellular organelles that fine tune the amount of calcium entering the cell. Cutting-edge and user-friendly, this volume presents relevant background information, critical analysis of the current observations and directions for future research. The book is intended for basic scientists specializing in cellular biology or ion transport, as well as for biomedical researchers.

From Knowledge Networks to Biological Models

Author : Anton Yuryev
Publisher : Bentham Science Publishers
ISBN 13 : 1608054373
Total Pages : 202 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis From Knowledge Networks to Biological Models by : Anton Yuryev

Download or read book From Knowledge Networks to Biological Models written by Anton Yuryev and published by Bentham Science Publishers. This book was released on 2012 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most findings about molecular interactions and cellular regulatory events are published in peer-reviewed scientific literature in the form of scientific jargon. the computerized text-mining algorithms are used to convert free grammar of human language into a set of formalized relationships between biological concepts in order to use this wealth of information. the compendium of such interactions extracted from an entire set of biomedical literature is a called knowledge network. Knowledge networks are the first step in the process of digitizing molecular biological knowledge. the next step is building molecular models depicting principal molecular events that govern various biological processes. Data mining in knowledge networks is the essence of building new biological models. the purpose is to elucidate major pathways of information flow through a molecular physical interaction network that happens during a disease, a cell process or an experiment. Such models contain key proteins involved in the process and can be used for prioritizing disease targets, for understanding of drug action and prevention of drug-induced toxicities, for analysis of patient predispositions and design of personalized therapies, for design of diagnostic biomarkers and analysis of patient molecular data. This e-book contains detailed examples illustrating the path to the digital biology and computerized drug development for personalized medicine. It provides conceptual principals for building biological models and for applying the models to make predictions relevant for drug development and translational medicine. The e-book will also be useful for researchers who use high-throughput technologies for molecular profiling of disease and drug action. It provides examples for analysis of gene expression microarrays to infer biological models, to find biomarkers for drug response and for applications of high-throughput molecular profiling technologies for personalized medicine. Scientists in academia, in pharmaceutical industry as well as graduate students will benefit from reading this book. the illustrations from the book can also be readily used in taught courses for molecular biology and pharmacology.