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Applying Systems Thinking To Regenerative Medicine
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Author :National Academies of Sciences, Engineering, and Medicine Publisher : ISBN 13 :9780309151825 Total Pages :170 pages Book Rating :4.1/5 (518 download)
Book Synopsis Applying Systems Thinking to Regenerative Medicine by : National Academies of Sciences, Engineering, and Medicine
Download or read book Applying Systems Thinking to Regenerative Medicine written by National Academies of Sciences, Engineering, and Medicine and published by . This book was released on 2021-12-26 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine products, which are intended to repair or replace damaged cells or tissues in the body, include a range of therapeutic approaches such as cell- and gene-based therapies, engineered tissues, and non-biologic constructs. The current approach to characterizing the quality of a regenerative medicine product and the manufacturing process often involves measuring as many endpoints as possible, but this approach has proved to be inadequate and unsustainable. The Forum on Regenerative Medicine of the National Academies of Sciences, Engineering, and Medicine convened experts across disciplines for a 2-day virtual public workshop to explore systems thinking approaches and how they may be applied to support the identification of relevant quality attributes that can help in the optimization of manufacturing and streamline regulatory processes for regenerative medicine. A broad array of stakeholders, including data scientists, physical scientists, industry researchers, regulatory officials, clinicians, and patient representatives, discussed new advances in data acquisition, data analysis and theoretical frameworks, and how systems approaches can be applied to the development of regenerative medicine products that can address the unmet needs of patients. This publication summarizes the presentation and discussion of the workshop.
Book Synopsis Regenerative Medicine by : Gustav Steinhoff
Download or read book Regenerative Medicine written by Gustav Steinhoff and published by Springer Science & Business Media. This book was released on 2011-02-04 with total page 1031 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative Medicine is a fastly emerging interdisciplinary field of research and clinical therapies on the repair, replacement or regeneration of cells, tissues or organs in congenital or acquired disease. This new field of research and clinical development focussing on stem cell science and regenerative biology is just starting to be the most fascinating and controversial medical development at the dawn of the 21st century. Viewing the great expectations to restructure and regenerate tissue, organs or organisms the current attempts of scientist and physicians are still in an early phase of development. This new textbook on “Regenerative Medicine – from protocol to patient” is aiming to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. The international leading experts from four continents describe the latest scientific and clinical knowledge of the field of “Regenerative Medicine”. The process of translating science of laboratory protocols into therapies is explained in sections on basic science, clinical translation, regulatory, ethical and industrial issues. The textbook is aiming to give the student, the researcher, the health care professional, the physician, and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practised therapies in Regenerative Medicine.
Book Synopsis Regenerative Medicine by : Gustav Steinhoff
Download or read book Regenerative Medicine written by Gustav Steinhoff and published by Springer Science & Business Media. This book was released on 2013-03-20 with total page 1211 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of regenerative medicine has developed rapidly over the past 20 years with the advent of molecular and cellular techniques. This textbook, Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from four continents describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. This textbook is organized into five parts: (I) Biology of Tissue Regeneration, (II) Stem Cell Science and Technology, (III) Tissue Engineering, Biomaterials and Nanotechnology, (IV) Regenerative Therapies and (V) Regulation and Ethics. The textbook aims to give the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine.
Book Synopsis Regenerative Medicine - from Protocol to Patient by : Gustav Steinhoff
Download or read book Regenerative Medicine - from Protocol to Patient written by Gustav Steinhoff and published by Springer. This book was released on 2016-04-12 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology as well as advanced molecular and cellular techniques. This collection of volumes, Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from all over the world describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. The collection is organized into five volumes: (1) Biology of Tissue Regeneration, (2) Stem Cell Science and Technology, (3) Tissue Engineering, Biomaterials and Nanotechnology, (4) Regenerative Therapies I, and (5) Regenerative Therapies II. The textbook gives the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine. Volume 3: Tissue engineering, Biomaterials and Nanotechnology focuses the development of technologies, which enable an efficient transfer of therapeutic genes and drugs exclusively to target cells and potential bioactive materials for clinical use. Principles of tissue engineering, vector technology, multifunctionalized nanoparticles, biodegradable materials, controlled release, and biointerface technology are described with regard to the development of new clinical cell technology. Imaging and targeting technologies as well as biological aspects of tissue and organ engineering are depicted.
Book Synopsis Essentials of Regenerative Medicine in Interventional Pain Management by : Annu Navani
Download or read book Essentials of Regenerative Medicine in Interventional Pain Management written by Annu Navani and published by Springer Nature. This book was released on with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Stem Cells in Regenerative Medicine by : Alain A. Vertes
Download or read book Stem Cells in Regenerative Medicine written by Alain A. Vertes and published by John Wiley & Sons. This book was released on 2015-12-02 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a unique guide to emerging stem cell technologies and the opportunities for their commercialisation. It provides in-depth analyses of the science, business, legal, and financing fundamentals of stem cell technologies, offering a holistic assessment of this emerging and dynamic segment of the field of regenerative medicine. • Reviews the very latest advances in the technology and business of stem cells used for therapy, research, and diagnostics • Identifies key challenges to the commercialisation of stem cell technology and avenues to overcome problems in the pipeline • Written by an expert team with extensive experience in the business, basic and applied science of stem cell research This comprehensive volume is essential reading for researchers in cell biology, biotechnology, regenerative medicine, and tissue engineering, including scientists and professionals, looking to enter commercial biotechnology fields.
Book Synopsis The Promises and Challenges of Regenerative Medicine by : John Morser
Download or read book The Promises and Challenges of Regenerative Medicine written by John Morser and published by Springer Science & Business Media. This book was released on 2007-01-19 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the advances in stem cell research. This book discusses the analysis and use of stem cells in basic biology, and their application in clinical practice.
Book Synopsis Regenerative Medicine - from Protocol to Patient by : Gustav Steinhoff
Download or read book Regenerative Medicine - from Protocol to Patient written by Gustav Steinhoff and published by Springer. This book was released on 2016-06-07 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology as well as advanced molecular and cellular techniques. This collection of volumes on Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from all over the world describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. This collection is organized into five volumes: (1) Biology of Tissue Regeneration, (2) Stem Cell Science and Technology, (3) Tissue Engineering, Biomaterials and Nanotechnology, (4) Regenerative Therapies I, and (5) Regenerative Therapies II. The textbook gives the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine. Volume 4 first gives a survey on the historical background of science and development of regenerative therapies. Ethical, preclinical and regulatory issues for the introduction of new regenerative therapies are depicted as the current background for clinical translation. The clinical chapters describe the state of development for medical science, technology application, and clinical translation for the nervous system, head, and respiratory system.
Book Synopsis Systems Thinking in Medicine and New Drug Discovery by : Robert E. Smith
Download or read book Systems Thinking in Medicine and New Drug Discovery written by Robert E. Smith and published by Cambridge Scholars Publishing. This book was released on 2018-12-17 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Total Quality Management (TQM) and systems thinking are being used to improve all aspects of human health. This first book in a two-volume set details how the healthcare community is working with patients and their caregivers to improve healthcare and reduce its costs. Systems-based thinking encourages us to work together to look at the effects of new drugs on entire systems and not just single molecular targets. It also leads us to a better understanding of genetics and epigenetics, as well as the deep ecology of the human body. The healthcare community is developing targeted therapies that stimulate our own bodies to cure ourselves and eliminate the need for animal testing. This book will appeal to specialists, who will find recommendations on safer materials for 3D bioprinting and ways to analyze dietary supplements for toxic contaminants, and physicians, pharmacists and non-professionals, who will learn the important different ways that dietary supplements and prescription drugs are developed, sold and marketed.
Author :Engineering National Academies of Sciences (and Medicine) Publisher : ISBN 13 :9780309688185 Total Pages :0 pages Book Rating :4.6/5 (881 download)
Book Synopsis Understanding the Role of the Immune System in Improving Tissue Regeneration by : Engineering National Academies of Sciences (and Medicine)
Download or read book Understanding the Role of the Immune System in Improving Tissue Regeneration written by Engineering National Academies of Sciences (and Medicine) and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Forum on Regenerative Medicine of the National Academies of Sciences, Engineering, and Medicine convened a two-day virtual public workshop to address knowledge gaps in the understanding of promising approaches to manipulate the immune system and/or the regenerative medicine product to improve outcomes of tissue repair and regeneration in patients. The workshop, titled 'Understanding the Role of the Immune System in Improving Tissue Regeneration,' explored the role of the immune system in the success or failure of regenerative medicine therapies. Participants considered potential strategies to effectively 'prepare' patients' immune systems to accept regenerative therapies and increase the likelihood of successful clinical outcomes and also discussed risks associated with modulating the immune system. This Proceedings of a Workshop highlights the presentations and discussions that occurred during the workshop"--
Book Synopsis Understanding the Role of the Immune System in Improving Tissue Regeneration: Proceedings of a Workshop by : National Academies Of Sciences Engineeri
Download or read book Understanding the Role of the Immune System in Improving Tissue Regeneration: Proceedings of a Workshop written by National Academies Of Sciences Engineeri and published by National Academies Press. This book was released on 2023-01-21 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Forum on Regenerative Medicine of the National Academies of Sciences, Engineering, and Medicine convened a two-day virtual public workshop to address knowledge gaps in the understanding of promising approaches to manipulate the immune system and/or the regenerative medicine product to improve outcomes of tissue repair and regeneration in patients. The workshop, titled Understanding the Role of the Immune System in Improving Tissue Regeneration, explored the role of the immune system in the success or failure of regenerative medicine therapies. Participants considered potential strategies to effectively prepare patients' immune systems to accept regenerative therapies and increase the likelihood of successful clinical outcomes and also discussed risks associated with modulating the immune system. This Proceedings of a Workshop highlights the presentations and discussions that occurred during the workshop.
Book Synopsis Principles of Regenerative Medicine by : Anthony Atala
Download or read book Principles of Regenerative Medicine written by Anthony Atala and published by Academic Press. This book was released on 2018-08-09 with total page 1456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Regenerative Medicine, Third Edition, details the technologies and advances applied in recent years to strategies for healing and generating tissue. Contributions from a stellar cast of researchers cover the biological and molecular basis of regenerative medicine, highlighting stem cells, wound healing and cell and tissue development. Advances in cell and tissue therapy, including replacement of tissues and organs damaged by disease and previously untreatable conditions, such as diabetes, heart disease, liver disease and renal failure are also incorporated to provide a view to the future and framework for additional studies. - Comprehensively covers the interdisciplinary field of regenerative medicine with contributions from leaders in tissue engineering, cell and developmental biology, biomaterials sciences, nanotechnology, physics, chemistry, bioengineering and surgery - Includes new chapters devoted to iPS cells and other alternative sources for generating stem cells as written by the scientists who made the breakthroughs - Edited by a world-renowned team to present a complete story of the development and promise of regenerative medicine
Author :Jan-thorsten Schantz Publisher :World Scientific Publishing Company ISBN 13 :9814520632 Total Pages :479 pages Book Rating :4.8/5 (145 download)
Book Synopsis A Manual For Current Therapies In Regenerative Medicine by : Jan-thorsten Schantz
Download or read book A Manual For Current Therapies In Regenerative Medicine written by Jan-thorsten Schantz and published by World Scientific Publishing Company. This book was released on 2013-04-30 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emerging field of regenerative medicine has led to a paradigm shift in therapeutic procedures. Scientific discovery in stem cell biology and material sciences, as well as in genetics have resulted in clinical concepts that focus on regeneration rather than repair. Also, translational research provided mankind with therapeutic tools to grow complex tissues and organs for transplantation into patients. These new technologies not only benefited patients but they also have significant socioeconomic potential.This manual aims to provide an overview on a variety of clinically applied strategies in the current field of regenerative medicine, and it also contains concise key data for a rapidly growing industry. As such, both patients and doctors will find the information contained within this manual to be useful and relevant. The editors are both international leaders in the field of regenerative medicine, and both possess a broad spectrum of experience from basic research to clinical application and commercialization.
Book Synopsis Regenerative Medicine - from Protocol to Patient by : Gustav Steinhoff
Download or read book Regenerative Medicine - from Protocol to Patient written by Gustav Steinhoff and published by Springer. This book was released on 2016-04-25 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology, as well as advanced molecular and cellular techniques. This collection of volumes on Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology, as well as the clinical application in different organ systems and diseases. International leading experts from all over the world describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. This collection is organized into five volumes: (1) Biology of Tissue Regeneration, (2) Stem Cell Science and Technology, (3) Tissue Engineering, Biomaterials and Nanotechnology, (4) Regenerative Therapies I, and (5) Regenerative Therapies II. The textbook gives the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine. Volume 1 contains eleven chapters addressing the latest basic science knowledge on the “Biology of Tissue Regeneration”. The principles of cell regeneration control by extracellular matrix and the biology of stem cell niches are explained. Depicted are the principles of molecular mechanisms controlling asymmetric cell division, stem cell differentiation, developmental and regenerative biology, epigenetic and genetic control as well as mathematical modelling for cell fate prediction. Regenerative biology of stem cells in the central nervous and cardiovascular systems leading to complex tissue regeneration in the model species axolotl and zebrafish, as well as the impact of immune signalling on nuclear reprogramming are outlined. These up to date accounts gives the readers advanced insights into the biological principles of the regenerative processes in stem cells, tissues and organisms.
Book Synopsis Regenerative Medicine - from Protocol to Patient by : Gustav Steinhoff
Download or read book Regenerative Medicine - from Protocol to Patient written by Gustav Steinhoff and published by Springer. This book was released on 2016-04-19 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology, as well as advanced molecular and cellular techniques. This collection of volumes on Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from all over the world describe the latest scientific and clinical knowledge of the field of regenerative medicine. The process of translating science of laboratory protocols into therapies is explained in sections on regulatory, ethical and industrial issues. This collection is organized into five volumes: (1) Biology of Tissue Regeneration, (2) Stem Cell Science and Technology, (3) Tissue Engineering, Biomaterials and Nanotechnology, (4) Regenerative Therapies I, and (5) Regenerative Therapies II. The textbook gives the student, the researcher, the health care professional, the physician and the patient a complete survey on the current scientific basis, therapeutical protocols, clinical translation and practiced therapies in regenerative medicine. Volume 2 contains sixteen chapters addressing advanced knowledge on “Stem Cell Science and Technology” addressing basic classification technology, cell biology of stemness state and regulatory molecular pathways. Mechanisms and technology of cell programming are explained, as well as the pathology of cancer cells and dedifferentiation signalling. Pluripotent, multipotent germline and tissue specific human stem cells are classified and qualified according to their respective biological function or tissue regeneration. Leading stem cell scientists from all over the world explain advanced technology, latest knowledge, and clinical implications of human stem cell science in a unique, comprehensive and detailed outline.
Book Synopsis Medical Advancements in Aging and Regenerative Technologies: Clinical Tools and Applications by : Daskalaki, Andriani
Download or read book Medical Advancements in Aging and Regenerative Technologies: Clinical Tools and Applications written by Daskalaki, Andriani and published by IGI Global. This book was released on 2012-11-30 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book translates basic science discoveries into regenerative therapies with the application of clinical tool in aging and tissue regeneration"--
