Applied Biopharmaceutics & Pharmacokinetics, Fifth Edition

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Publisher : McGraw Hill Professional
ISBN 13 : 0071501878
Total Pages : 914 pages
Book Rating : 4.0/5 (715 download)

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Book Synopsis Applied Biopharmaceutics & Pharmacokinetics, Fifth Edition by : Leon Shargel

Download or read book Applied Biopharmaceutics & Pharmacokinetics, Fifth Edition written by Leon Shargel and published by McGraw Hill Professional. This book was released on 2004-09-09 with total page 914 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most comprehensive text on the practical applications of biopharmaceuticals and pharmacokinetics! 4 STAR DOODY'S REVIEW! "The updated edition provides the reader with a solid foundation in the basic principles of pharmacokinetics and biopharmaceutics. Students will be able to apply the information to their clinical practice and researchers will find this to be a valuable reference. This modestly priced book should be the gold standard for student use."--Doody's Review Service The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.

Applied Biopharmaceutics & Pharmacokinetics, Fifth Edition

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Author :
Publisher : McGraw Hill Professional
ISBN 13 : 0071375503
Total Pages : 915 pages
Book Rating : 4.0/5 (713 download)

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Book Synopsis Applied Biopharmaceutics & Pharmacokinetics, Fifth Edition by : Leon Shargel

Download or read book Applied Biopharmaceutics & Pharmacokinetics, Fifth Edition written by Leon Shargel and published by McGraw Hill Professional. This book was released on 2004-08-19 with total page 915 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most comprehensive text on the practical applications of biopharmaceuticals and pharmacokinetics! 4 STAR DOODY'S REVIEW! "The updated edition provides the reader with a solid foundation in the basic principles of pharmacokinetics and biopharmaceutics. Students will be able to apply the information to their clinical practice and researchers will find this to be a valuable reference. This modestly priced book should be the gold standard for student use."--Doody's Review Service The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.

Applied Biopharmaceutics & Pharmacokinetics

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Author :
Publisher : McGraw-Hill Medical Publishing
ISBN 13 :
Total Pages : 920 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Applied Biopharmaceutics & Pharmacokinetics by : Leon Shargel

Download or read book Applied Biopharmaceutics & Pharmacokinetics written by Leon Shargel and published by McGraw-Hill Medical Publishing. This book was released on 2005 with total page 920 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.

Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition

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Publisher : McGraw Hill Professional
ISBN 13 : 007160393X
Total Pages : 831 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition by : Leon Shargel

Download or read book Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition written by Leon Shargel and published by McGraw Hill Professional. This book was released on 2012-04-11 with total page 831 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics The field’s leading text for more than three decades Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition provides you with a basic understanding of the principles of biopharmaceutics and pharmacokinetics and applies these principles to drug product development, drug product performance and drug therapy. The revised and updated sixth edition is unique in teaching basic concepts that relate to understanding the complex issues associated with safe and efficacious drug therapy. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics will help you to: Understand the basic concepts in biopharmaceutics and pharmacokinetics. Use raw data and derive the pharmacokinetic models and parameters that best describe the process of drug absorption, distribution, and elimination Critically evaluate biopharmaceutic studies involving drug product equivalency and unequivalency Design and evaluate dosage regimens of drugs, using pharmacokinetic and biopharmaceutic parameters Detect potential clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Practical problems and clinical examples with discussions are included in each chapter to help you apply these principles to patient care and drug consultation situations. Chapter Objectives, Chapter Summaries, and Frequently Asked Questions along with additional application questions appear within each chapter to identify and focus on key concepts. Most of the chapters have been revised to reflect our current understanding of drug product performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy.

Applied Biopharmaceutics & Pharmacokinetics, Seventh Edition

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Publisher : McGraw Hill Professional
ISBN 13 : 0071829644
Total Pages : 928 pages
Book Rating : 4.0/5 (718 download)

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Book Synopsis Applied Biopharmaceutics & Pharmacokinetics, Seventh Edition by : Leon Shargel

Download or read book Applied Biopharmaceutics & Pharmacokinetics, Seventh Edition written by Leon Shargel and published by McGraw Hill Professional. This book was released on 2015-11-22 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: The landmark textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics—now fully updated. Explains how to detect clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Helps you critically evaluate biopharmaceutic studies involving drug product equivalency and unequivalency Chapters have been revised to reflect the latest clinical perspectives on drug performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy The field’s leading text for more than three decades, Applied Biopharmaceutics & Pharmacokinetics gets you up to speed on the basics of the discipline like no other resource. Practical problems and clinical examples with discussions are integrated within each chapter to help you apply principles to patient care and drug consultation situations. In addition, outstanding pedagogy, including chapter objectives, chapter summaries, and FAQs, plus additional application questions, identify and focus on key concepts. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics shows you how to use raw data and formulate the pharmacokinetic models and parameters that best describe the process of drug absorption, distribution, and elimination. The book also helps you work with pharmacokinetic and biopharmaceutic parameters to design and evaluate dosage regimens of drugs. In the seventh edition of this must-have interactive learning tool, most of the chapters are updated to reflect our current understanding of complex issues associated with safe and efficacious drug therapy.

Applied Biopharmaceutics and Pharmacokinetics

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Publisher : McGraw-Hill/Appleton & Lange
ISBN 13 :
Total Pages : 656 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Applied Biopharmaceutics and Pharmacokinetics by : Leon Shargel

Download or read book Applied Biopharmaceutics and Pharmacokinetics written by Leon Shargel and published by McGraw-Hill/Appleton & Lange. This book was released on 1993 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this introductory text covers the factors which influence the release of the drug from the drug product and how the body handles the drug. A stronger focus has been placed on the basics with clear explanations and illustrated examples. There is also more information on statistics and population pharmacokinetics and new chapters on drug distribution, computer applications, enzyme kinetics and pharmacokinetics models.

Applied Biopharmaceutics and Pharmacokinetics

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Publisher :
ISBN 13 : 9780071240055
Total Pages : pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Applied Biopharmaceutics and Pharmacokinetics by : Shargel

Download or read book Applied Biopharmaceutics and Pharmacokinetics written by Shargel and published by . This book was released on 2003-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing on the application and understanding of concepts, this book provides basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.

Shargel and Yu's Applied Biopharmaceutics & Pharmacokinetics, 8th Edition

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Publisher : McGraw Hill Professional
ISBN 13 : 1260143007
Total Pages : 1035 pages
Book Rating : 4.2/5 (61 download)

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Book Synopsis Shargel and Yu's Applied Biopharmaceutics & Pharmacokinetics, 8th Edition by : Leon Shargel

Download or read book Shargel and Yu's Applied Biopharmaceutics & Pharmacokinetics, 8th Edition written by Leon Shargel and published by McGraw Hill Professional. This book was released on 2022-01-24 with total page 1035 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authoritative textbook on the principles and practical applications of biopharmaceutics and pharmacokinetics Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics has been the standard textbook in its field for over 40 years. This eighth edition includes recent scientific developments in the field and embodies the collective contribution of experts with deep knowledge and experience in the selected subject areas. Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition provides the reader with a fundamental understanding of biopharmaceutics and pharmacokinetics principles that can be applied to patient drug therapy and rational drug product development. Shargel & Yu's Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition has been expanded and revised to include advancements in biopharmaceutics and pharmacokinetics. The chapter sequence has been reorganized into four main sections, providing a more logical sequence for students. The textbook starts with fundamental concepts, followed by application of these principles to optimize drug therapy and to the rational development of drug products. Each chapter includes theoretical concepts with practical examples and clinical applications. Frequently asked questions provide a discussion of overall concepts. Features: Expanded and revised chapters to include scientific advances in biopharmaceutics and pharmacokinetics Four main sections providing a natural buildup of knowledge: introduction to biopharmaceutics and pharmacokinetics, fundamentals of biopharmaceutics, pharmacokinetic calculations, clinical pharmacokinetics and pharmacodynamics, and biopharmaceutics and pharmacokinetics in drug product development Additional chapters for this edition include: o Physiological factors related to drug absorption o Approaches to pharmacokinetics and pharmacodynamics calculations o Novel and complex dosage Forms o Clinical Development and Therapeutic Equivalence of Generic Drug and Biosimilar Products o Pharmacokinetics and Pharmacodynamics in Clinical Drug Product Development Additional information on drug therapy, drug product performance, and other related topics Frequently asked questions, practice problems, clinical examples and learning questions

Applied Biopharmaceutics & Pharmacokinetics, Eigth Edition

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Publisher : McGraw-Hill Education / Medical
ISBN 13 : 9781260142990
Total Pages : 864 pages
Book Rating : 4.1/5 (429 download)

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Book Synopsis Applied Biopharmaceutics & Pharmacokinetics, Eigth Edition by : Andrew B.C. Yu

Download or read book Applied Biopharmaceutics & Pharmacokinetics, Eigth Edition written by Andrew B.C. Yu and published by McGraw-Hill Education / Medical. This book was released on 2020-12-06 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. This authoritative guide has been updated with important new findings about drug therapy, product performance, and other need-to-know topics Applied Biopharmaceutics & Pharmacokinetics, Eighth Edition delivers the knowledge and skills you need to succeed. The authors provide practical problems with specific examples of clinical solutions to help you apply principles to patient care and drug consultation situations. Each chapter includes objectives, summaries, and FAQs highlighting that help you understand and retain key concepts. You’ll learn how to derive models/parameters to describe drug absorption, distribution, and elimination processes; evaluate biopharmaceutic studies involving drug product equivalency and unequivalency; design and evaluate dosage regimens of drugs; detect and solve clinical pharmacokinetic problems; and much more.

ADMET for Medicinal Chemists

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Publisher : John Wiley & Sons
ISBN 13 : 9780470922811
Total Pages : 512 pages
Book Rating : 4.9/5 (228 download)

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Book Synopsis ADMET for Medicinal Chemists by : Katya Tsaioun

Download or read book ADMET for Medicinal Chemists written by Katya Tsaioun and published by John Wiley & Sons. This book was released on 2011-02-15 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the drug discovery interface; it defines and reviews the field of ADME for medicinal chemists. In addition, the scientific principles and the tools utilized by ADME scientists in a discovery setting, as applied to medicinal chemistry and structure modification to improve drug-like properties of drug candidates, are examined.

Modern Pharmaceutics Volume 1

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Publisher : CRC Press
ISBN 13 : 1420065653
Total Pages : 656 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Modern Pharmaceutics Volume 1 by : Alexander T. Florence

Download or read book Modern Pharmaceutics Volume 1 written by Alexander T. Florence and published by CRC Press. This book was released on 2009-05-28 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: With over 100 illustrations, Volume 1 addresses the core disciplines of pharmaceutics (absorption, PK, excipients, tablet dosage forms, and packaging), and explores the challenges and paradigms of pharmaceutics. Key topics in Volume 1 include: • principles of drug absorption, chemical kinetics, and drug stability • pharmacokinetics • the effect of route of administration and distribution on drug action • in vivo imaging of dose forms: gamma scintigraphy, PET imaging NMR, MRI, etc. • powder technology • excipient design and characterization • preformulation • optimization techniques in pharmaceutical formulation and processing • disperse and surfactant systems • the solid state, tablet dosage forms, coating processes, and hard and soft shell capsules • parenteral products

Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems

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Publisher : Springer Nature
ISBN 13 : 303083395X
Total Pages : 437 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems by : Jayvadan K. Patel

Download or read book Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems written by Jayvadan K. Patel and published by Springer Nature. This book was released on 2022-03-07 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems. No other consolidated published reference discusses the PK/PD study of nanoparticle drug delivery systems. This book discusses the advantages of nanoparticle drug delivery systems (NPDDS) in enhancing the pharmacokinetics of many drugs that are not easily metabolized or that obtain the desired therapeutic effect with minimum toxicity. The authors provide an overview of biodistribution with a focus on polymer and lipid nanoparticles. This thorough reference is divided into three parts: Modelling, Specific carries and their potential to treat specific diseases.

Generic Drug Product Development

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Publisher : CRC Press
ISBN 13 : 1420020013
Total Pages : 288 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Generic Drug Product Development by : Isadore Kanfer

Download or read book Generic Drug Product Development written by Isadore Kanfer and published by CRC Press. This book was released on 2007-11-15 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The assessment of bioequivalence is an important process whereby the bioavailability of a generic drug product is compared with its brand-name counterpart. Generic pharmaceutical products must be approved as therapeutic equivalents to the brand name alternative in order to be interchangeable. The demonstration of bioequivalence is an important component of therapeutic equivalence. Bioequivalence studies are very expensive, time consuming and always have the possibility of failure. The objective of this textbook is to describe some of those specific bioequivalence issues which need to be considered for the design and conduct of bioequivalence studies. By exploring scientific, legal, and international regulatory challenges, Generic Drug Development, discusses the use of alternative approaches to the measurement of plasma drug concentrations for the demonstration of bioequivalence, and covers bioequivalence procedures for drug products that are not easily assessed - based upon the physical and chemical properties of the active drug and the nature of the drug product.

Handbook of Drug Metabolism, Third Edition

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Publisher : CRC Press
ISBN 13 : 1482262045
Total Pages : 755 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Handbook of Drug Metabolism, Third Edition by : Paul G. Pearson

Download or read book Handbook of Drug Metabolism, Third Edition written by Paul G. Pearson and published by CRC Press. This book was released on 2019-05-20 with total page 755 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book continues to be the definitive reference on drug metabolism with an emphasis on new scientific and regulatory developments. It has been updated based on developments that have occurred in the last 5 years, with new chapters on large molecules disposition, stereo-selectivity in drug metabolism, drug transporters and metabolic activation of drugs. Some chapters have been prepared by new authors who have emerged as subject area experts in the decade that has passed since publication of the first edition.

Dosage Form Design Considerations

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Publisher : Academic Press
ISBN 13 : 0128144246
Total Pages : 820 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Dosage Form Design Considerations by :

Download or read book Dosage Form Design Considerations written by and published by Academic Press. This book was released on 2018-07-28 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dosage Form Design Parameters, Volume I, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries. Examines the history and recent developments in drug dosage forms for pharmaceutical sciences Focuses on physicochemical aspects, prefomulation solid state properties and polymorphism Contains extensive references for further discovery and learning that are appropriate for advanced undergraduates, graduate students and those interested in drug dosage design

The Practice of Medicinal Chemistry

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Publisher : Academic Press
ISBN 13 : 0080568777
Total Pages : 982 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis The Practice of Medicinal Chemistry by : Camille Georges Wermuth

Download or read book The Practice of Medicinal Chemistry written by Camille Georges Wermuth and published by Academic Press. This book was released on 2011-05-02 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Practice of Medicinal Chemistry fills a gap in the list of available medicinal chemistry literature. It is a single-volume source on the practical aspects of medicinal chemistry. Considered ""the Bible"" by medicinal chemists, the book emphasizes the methods that chemists use to conduct their research and design new drug entities. It serves as a practical handbook about the drug discovery process, from conception of the molecules to drug production. The first part of the book covers the background of the subject matter, which includes the definition and history of medicinal chemistry, the measurement of biological activities, and the main phases of drug activity. The second part of the book presents the road to discovering a new lead compound and creating a working hypothesis. The main parts of the book discuss the optimization of the lead compound in terms of potency, selectivity, and safety. The Practice of Medicinal Chemistry can be considered a ""first-read"" or ""bedside book"" for readers who are embarking on a career in medicinal chemistry. NEW TO THIS EDITION: * Focus on chemoinformatics and drug discovery * Enhanced pedagogical features* New chapters including: - Drug absorption and transport - Multi-target drugs* Updates on hot new areas: NEW! Drug discovery and the latest techniques NEW! How potential drugs can move through the drug discovery/ development phases more quickly NEW! Chemoinformatics

Essentials of Biopharmaceutics and Pharmacokinetics - E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 813123262X
Total Pages : 370 pages
Book Rating : 4.1/5 (312 download)

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Book Synopsis Essentials of Biopharmaceutics and Pharmacokinetics - E-Book by : Ashutosh Kar

Download or read book Essentials of Biopharmaceutics and Pharmacokinetics - E-Book written by Ashutosh Kar and published by Elsevier Health Sciences. This book was released on 2010-09-15 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Biopharmaceutics and Pharmacokinetics Kar’s Essentials of Biopharmaceutics and Pharmacokinetics deals with how a drug exerts its action in the human body through the fundamentals of absorption, distribution, metabolism and excretion. The book adopts a growth-oriented format and design that is developed systematically and methodically. The book interrelates five different sections: Section 1 Biopharmaceutics and Pharmacokinetics: What Do They Mean? Section 2 Biopharmaceutics Section 3 Pharmacokinetics Section 4 Clinical Pharmacokinetics Section 5 Bioavailability and Bioequivalence Each section starts with a basic theory and fields of application, focuses on model-independent pharmacokinetic analyses, expatiates various biopharmaceutical aspects of dosage form and evaluation, provides an altogether new approach in understanding both dosage regimen design and individualization, and explains modification in drug molecules related to the pharmacokinetics. Undoubtedly, the unique blend of fundamental principles and latest breakthroughs in the field will certainly provide sufficient subject matter to the students of pharmacy, pharmacology, medicinal chemistry scientists, who need a simple as well as detailed introduction in theory and application.