Applications Of Mass Spectrometry For The Provision Of Forensic Intelligence

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Applications of Mass Spectrometry for the Provision of Forensic Intelligence

Author : Simona Francese
Publisher : Royal Society of Chemistry
ISBN 13 : 1837671931
Total Pages : 243 pages
Book Rating : 4.8/5 (376 download)

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Book Synopsis Applications of Mass Spectrometry for the Provision of Forensic Intelligence by : Simona Francese

Download or read book Applications of Mass Spectrometry for the Provision of Forensic Intelligence written by Simona Francese and published by Royal Society of Chemistry. This book was released on 2023-12-20 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass spectrometry is one of the most versatile analytical techniques due to the vast range of analytes that it can detect and quantify and, as such, for its contribution to a significant number of life science fields. The legal and forensics community has certainly benefited from this technique, which has been able to provide reliable evidence in court cases. Liquid Chromatography/Gas Chromatography–Mass Spectrometry (LC/GC–MS) still have a dominant role in the provision of forensic intelligence. However, in the past decade new and exciting MS-based techniques have emerged and are or have evolved to be at an operational deployment maturity, enabling either fast, ambient, non-destructive, or portable screening (or encompass all of these features). In this book, developments of LC–MS and GC–MS based techniques are covered with respect to operational practice and new applications, accompanied by other MS-based techniques that are increasing forensic opportunities and that operate on a variety of evidence types. Whilst the underpinning working principles of each relevant mass spectrometry technique are summarised, each chapter primarily focuses on its implementation in criminal investigation and court cases. In the last chapters, this book additionally covers emerging MS technologies that are at the beginning of their operational implementation journey as well as niche applications outside the fields of traditional forensic science but with a clear potential to impact future investigations (forensics beyond the courtroom). This book provides an up-to-date reference for the mass spectrometry-based tools that are currently available both as established and as emerging methods within forensic practice. It will help casework commissioning managers and forensic providers worldwide to make more informed decisions as to the forensic strategy and workflow when examining exhibits. It is also recommended to postgraduates and early career investigators with reference to the contribution that these techniques and methods could make if applied to classic forensic science practice.

Applications of Mass Spectrometry for the Provision of Forensic Intelligence: State-of-the-art and Perspectives

Author : Simona Francese
Publisher : Royal Society of Chemistry
ISBN 13 : 1839168110
Total Pages : 322 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Applications of Mass Spectrometry for the Provision of Forensic Intelligence: State-of-the-art and Perspectives by : Simona Francese

Download or read book Applications of Mass Spectrometry for the Provision of Forensic Intelligence: State-of-the-art and Perspectives written by Simona Francese and published by Royal Society of Chemistry. This book was released on 2023-12-20 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Glycoprotein Analysis

Author : Weston B Struwe
Publisher : Royal Society of Chemistry
ISBN 13 : 1839166444
Total Pages : 417 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Glycoprotein Analysis by : Weston B Struwe

Download or read book Glycoprotein Analysis written by Weston B Struwe and published by Royal Society of Chemistry. This book was released on 2024-10-16 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycoproteins are central to numerous cellular processes and are among the most structurally complex biomolecules in nature. This unique complexity stems from variability in complex oligosaccharides that are located throughout the protein, a feature that is profoundly important for regulating biomolecular interactions but also makes glycoproteins difficult to study. As such, glycoprotein analysis entails a range of techniques to bridge the knowledge gap between glycoprotein structure and biological function. This book serves as an authoritative guide to glycoprotein analysis, written by internationally recognised experts in the field and discussed in the context of real-world applications across the life sciences. It provides a wide-ranging assessment of the modern methods, from those used to characterise glycoprotein structure, to approaches proficient in uncovering the molecular mechanisms by which they function as well as those capable of measuring structural dynamics and macromolecular assembly. These methods differ to a large extent and include mass spectrometry, glycan/lectin arrays, nuclear magnetic resonance, infrared spectroscopy, scanning probe microscopy and high-performance liquid chromatography. Equally important are computational techniques, including molecular dynamics and bioinformatics, which are also covered and discussed in the wider context of glycoprotein analysis. Glycobiology is indeed a rapidly growing field and the development of advanced tools for glycoproteins analysis has been enabled by researchers from different backgrounds working to overcome long-standing analytical challenges and biological questions involving glycosylation. This book is intended to aid academic and professional researchers at various levels of their career to gain a deeper appreciation of cutting-edge methods in glycoprotein analysis and their applications in biomolecular research, biotherapeutic development, structural biology and biophysical chemistry.

Direct Analysis in Real Time Mass Spectrometry

Author : Yiyang Dong
Publisher : John Wiley & Sons
ISBN 13 : 3527341846
Total Pages : 370 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Direct Analysis in Real Time Mass Spectrometry by : Yiyang Dong

Download or read book Direct Analysis in Real Time Mass Spectrometry written by Yiyang Dong and published by John Wiley & Sons. This book was released on 2018-04-09 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clear, comprehensive, and state of the art, the groundbreaking book on the emerging technology of direct analysis in real time mass spectrometry Written by a noted expert in the field, Direct Analysis in Real Time Mass Spectrometry offers a review of the background and the most recent developments in DART-MS. Invented in 2005, DART-MS offers a wide range of applications for solving numerous analytical problems in various environments, including food science, forensics, and clinical analysis. The text presents an introduction to the history of the technology and includes information on the theoretical background, for exampleon the ionization mechanism. Chapters on sampling and coupling to different types of mass spectrometers are followed by a comprehensive discussion of a broad range of applications. Unlike most other ionization methods, DART does not require laborious sample preparation, as ionization takes place directly on the sample surface. This makes the technique especially attractive for applications in forensics and food science. Comprehensive in scope, this vital text: -Sets the standard on an important and emerging ionization technique -Thoroughly discusses all the relevant aspects from instrumentation to applications -Helps in solving numerous analytical problems in various applications, for example food science, forensics, environmental and clinical analysis -Covers mechanisms, coupling to mass spectrometers, and includes information on challenges and disadvantages of the technique Academics, analytical chemists, pharmaceutical chemists, clinical chemists, forensic scientists, and others will find this illuminating text a must-have resource for understanding the most recent developments in the field.

Advances in Analytical Techniques for Forensic Investigation

Author : Priyanka Chhabra
Publisher : John Wiley & Sons
ISBN 13 : 1394167326
Total Pages : 319 pages
Book Rating : 4.3/5 (941 download)

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Book Synopsis Advances in Analytical Techniques for Forensic Investigation by : Priyanka Chhabra

Download or read book Advances in Analytical Techniques for Forensic Investigation written by Priyanka Chhabra and published by John Wiley & Sons. This book was released on 2024-08-06 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is essential for anyone seeking to understand and apply the latest analytical techniques in forensic investigation, saving time, materials, energy, and manpower by providing guidance on the most appropriate techniques for different types of investigations. Advances in Analytical Techniques for Forensic Investigation is aimed to describe the applicability of different types of analytical techniques used for the forensic investigation, including FT-IR, chromatography, mass spectroscopy, NMR spectroscopy, atomic absorption spectroscopy, UV- vis spectroscopy, etc. This book will focus on current and emerging developments in the latest analytical techniques and methods used in the forensic investigation and sample analysis of various physical, chemical, and biological samples in order to facilitate the smooth conduction of justice.

Emerging Technologies for the Analysis of Forensic Traces

Author : Simona Francese
Publisher : Springer Nature
ISBN 13 : 3030205428
Total Pages : 287 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Emerging Technologies for the Analysis of Forensic Traces by : Simona Francese

Download or read book Emerging Technologies for the Analysis of Forensic Traces written by Simona Francese and published by Springer Nature. This book was released on 2019-09-30 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a line of communication between academia and end users/practitioners to advance forensic science and boost its contribution to criminal investigations and court cases. By covering the state of the art of promising technologies for the analysis of trace evidence using a controlled vocabulary, this book targets the forensics community as well as, crucially, informing the end users on novel and potential forensic opportunities for the fight against crime. By reporting end users commentaries at the end of each chapter, the relevant academic community is provided with clear indications on where to direct further technological developments in order to meet the law requirements for operational deployment, as well as the specific needs of the end users. Promising chemistry based technologies and analytical techniques as well as techniques that have already shown to various degrees an operational character are covered. The majority of the techniques covered have imaging capabilities, that is the ability to visualize the distribution of the target molecules within the trace evidence recovered. This feature enhances intelligibility of the information making it also accessible to a lay audience such as that typically found with a court jury. Trace evidence discussed in this book include fingermarks, bodily fluids, hair, gunshot residues, soil, ink and questioned documents thus covering a wide range of possible evidence recovered at crime scenes.

Gas Chromatography In Forensic Science

Author : Ian Tebbett
Publisher : CRC Press
ISBN 13 : 0203016416
Total Pages : 198 pages
Book Rating : 4.2/5 (3 download)

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Book Synopsis Gas Chromatography In Forensic Science by : Ian Tebbett

Download or read book Gas Chromatography In Forensic Science written by Ian Tebbett and published by CRC Press. This book was released on 1992-10-31 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the application of gas chromatography to various aspects of forensic chemistry. Following an introduction to the basic theory of chromatographic separations, the text discusses specific issues, such as drug analysis, fires and explosives, alcohol and toxicology.

Advances in Forensic Human Identification

Author : Xanthe Mallett
Publisher : CRC Press
ISBN 13 : 1439825149
Total Pages : 476 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Advances in Forensic Human Identification by : Xanthe Mallett

Download or read book Advances in Forensic Human Identification written by Xanthe Mallett and published by CRC Press. This book was released on 2014-01-24 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: As forensic human identification receives increased global attention, practitioners, policy makers, and students need an appropriate resource that describes current methods and modalities that have shaped today’s policies and protocols. A supplemental follow-up to Forensic Human Identification: An Introduction, Advances in Forensic Human Identification covers advances in the most well-known scientific techniques and discusses new and developing subjects and modalities of human identification. A collection of contributions from worldwide experts, the book embraces a broad context and looks at several issues beyond physical identification of human remains or offenders. The book examines online, sexual, and biometric identities and discusses problems associated with investigative practice, such as the developing use of the Internet as a distribution and communication medium for criminal activities. It also explores miscarriages of justice that can result from flawed applications or interpretations of forensic evidence. Finally, it looks at the future of forensic science in the United Kingdom in light of financial challenges and the closure of the Forensic Science Service. Where appropriate, case studies illustrate the use of techniques and the associated problems described in the text. A supplemental CD includes images in full color. This volume provides an important contribution to the ongoing practitioner and academic debates surrounding the application of forensic technologies. The insight presented is destined to springboard further inquiry into enhanced techniques and underlies the need for more research into the appropriate use of identification techniques to solve the mysteries of the unknown.

Magnetic Resonance and its Applications in Drug Formulation and Delivery

Author : Michael D Mantle
Publisher : Royal Society of Chemistry
ISBN 13 : 1839160020
Total Pages : 390 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Magnetic Resonance and its Applications in Drug Formulation and Delivery by : Michael D Mantle

Download or read book Magnetic Resonance and its Applications in Drug Formulation and Delivery written by Michael D Mantle and published by Royal Society of Chemistry. This book was released on 2024-03-27 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book details the latest research and development in the use of magnetic resonance imaging and spectroscopy as tools to give quantitative insights concerning late stage pharmaceutical formulation, tablet manufacturing and drug dissolution behaviour. The book combines different facets of magnetic resonance and highlights the use of spatial resolution (MRI) and how this adds to the knowledge base to further our understanding of the microscopic physicochemical processes occurring during drug release from solid dosage forms. New topics, that have not been thoroughly reviewed elsewhere, are covered including the applications of solution state magnetic resonance in process scale up, reaction monitoring/understanding and process analytical technologies (PAT); dissolution testing; and counterfeit analysis. Solid state NMR and its role in understanding phase separation in dispersions, polymorphism and crystallography are included and magnetic resonance imaging and its use in assessing tablet dissolution performance, mass transport and mixing in hot melt extrusion (HME) are covered. Focusing on late stage development rather than molecular drug discovery provides a unique approach and the book will appeal to a diversity of disciplines using spectroscopy for study. Aimed at researchers in drug development, manufacture and formulation in both industry (pharmaceutical companies) and academia (pharmacy program), it includes examples, where appropriate, of studies on commercially available pharmaceutical products.

Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry

Author : Haroun N. Shah
Publisher : John Wiley & Sons
ISBN 13 : 1119814073
Total Pages : 565 pages
Book Rating : 4.1/5 (198 download)

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Book Synopsis Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry by : Haroun N. Shah

Download or read book Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry written by Haroun N. Shah and published by John Wiley & Sons. This book was released on 2023-03-29 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry Detailed resource presenting the capabilities of MALDI mass spectrometry (MS) to industrially and environmentally significant areas in the biosciences Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry fulfills a need to bring the key analytical technique of MALDI mass spectrometric analysis into routine practice by specialists and non-specialists, and technicians. It informs and educates established researchers on the development of techniques as applied to industrially significant areas within the biosciences. Throughout the text, the reader is presented with recognized and emerging techniques of this powerful and continually advancing field of analytical science to key areas of importance. While many scientific papers are reporting new applications of MS-based analysis in specific foci, this book is unique in that it draws together an incredibly diverse range of applications that are pushing the boundaries of MS across the broad field of biosciences. Contributed to by recognized experts in the field of MALDI MS who have been key players in promoting the advancement and dissemination of authoritative information in this field, Microbiological Identification using MALDI-TOF and Tandem Mass Spectrometry covers sample topics such as: Oil microbiology, marine and freshwater ecosystems, agricultural and food microbiology, and industrial waste microbiology Bioremediation and landfill sites microbiology, microbiology of inhospitable sites (e.g. Arctic and Antarctic, and alkaline and acidic sites, and hot temperatures) Veterinary, poultry and animals, viral applications of MS, and antibiotic resistance using tandem MS methods Recent developments which are set to transform the use of MS from its success in clinical microbiology to a wide range of commercial and environmental uses Bridging the gap between measurement and key applications, this text is an ideal resource for industrial and environmental analytical scientists, including technologists in the food industry, pharmaceuticals, and agriculture, as well as biomedical scientists, researchers, clinicians and academics and scientists in bio-resource centers.

Strengthening Forensic Science in the United States

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309142393
Total Pages : 348 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Strengthening Forensic Science in the United States by : National Research Council

Download or read book Strengthening Forensic Science in the United States written by National Research Council and published by National Academies Press. This book was released on 2009-07-29 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scores of talented and dedicated people serve the forensic science community, performing vitally important work. However, they are often constrained by lack of adequate resources, sound policies, and national support. It is clear that change and advancements, both systematic and scientific, are needed in a number of forensic science disciplines to ensure the reliability of work, establish enforceable standards, and promote best practices with consistent application. Strengthening Forensic Science in the United States: A Path Forward provides a detailed plan for addressing these needs and suggests the creation of a new government entity, the National Institute of Forensic Science, to establish and enforce standards within the forensic science community. The benefits of improving and regulating the forensic science disciplines are clear: assisting law enforcement officials, enhancing homeland security, and reducing the risk of wrongful conviction and exoneration. Strengthening Forensic Science in the United States gives a full account of what is needed to advance the forensic science disciplines, including upgrading of systems and organizational structures, better training, widespread adoption of uniform and enforceable best practices, and mandatory certification and accreditation programs. While this book provides an essential call-to-action for congress and policy makers, it also serves as a vital tool for law enforcement agencies, criminal prosecutors and attorneys, and forensic science educators.

Mass Spectrometry Handbook

Author : Mike S. Lee
Publisher : John Wiley & Sons
ISBN 13 : 1118180720
Total Pages : 1362 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Mass Spectrometry Handbook by : Mike S. Lee

Download or read book Mass Spectrometry Handbook written by Mike S. Lee and published by John Wiley & Sons. This book was released on 2012-04-16 with total page 1362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields.

MALDI Mass Spectrometry Imaging

Author : Tiffany Porta Siegel
Publisher : Royal Society of Chemistry
ISBN 13 : 1839165200
Total Pages : 403 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis MALDI Mass Spectrometry Imaging by : Tiffany Porta Siegel

Download or read book MALDI Mass Spectrometry Imaging written by Tiffany Porta Siegel and published by Royal Society of Chemistry. This book was released on 2021-11-23 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers, in a single resource, knowledge about matrix-assisted laser desorption ionisation (MALDI) mass spectrometry imaging. It includes fundamentals in the MALDI ionisation process, different source geometries and capabilities, detection systems and the latest research and applications in the range of –omics area as well as other broader areas. Chapters will touch on dedicated sample preparation protocols specific for the class of compounds of interest, instrumentation used with strengths and current limitations, strategies for structural analysis and identification and applications. It will be a welcomed addition to the literature in this fast-moving field and provide a guide to new innovations and applications especially in metabolomics and proteomics. With contributions from leading experts, this book will be an authoritative guide to this method. Aimed at postgraduate and professional researchers, in academia and in the industrial market where it has direct application to clinical research. It will be a supporting volume for those just entering the field as well as experienced practitioners.

Microbial Forensics

Author : Bruce Budowle
Publisher : Academic Press
ISBN 13 : 0123820073
Total Pages : 753 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Microbial Forensics by : Bruce Budowle

Download or read book Microbial Forensics written by Bruce Budowle and published by Academic Press. This book was released on 2010-10-27 with total page 753 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Forensics is a rapidly evolving scientific discipline. In the last decade, and particularly due to the anthrax letter attacks in the United States, microbial forensics has become more formalized and has played an increasingly greater role in crime investigations. This has brought renewed interest, development and application of new technologies, and new rules of forensic and policy engagement. It has many applications ranging from biodefense, criminal investigations, providing intelligence information, making society more secure, and helping protect precious resources, particularly human life. A combination of diverse areas is investigated, including the major disciplines of biology, microbiology, medicine, chemistry, physics, statistics, population genetics, and computer science. Microbial Forensics, Second Edition is fully revised and updated and serves as a complete reference of the discipline. It describes the advances, as well as the challenges and opportunities ahead, and will be integral in applying science to help solve future biocrimes. - A collection of microbiology, virology, toxicology and mycology as it relates to forensics, in one reference - New and expanded content to include statistical analysis of forensic data and legal admissibility and the standards of evidence, to name a few - Includes research information and application of that research to crime scene analysis, which will allow practitioners to understand and apply the knowledge to their practice with ease

Advances in Forensic Applications of Mass Spectrometry

Author : Jehuda Yinon
Publisher : CRC Press
ISBN 13 : 0203998286
Total Pages : 300 pages
Book Rating : 4.2/5 (39 download)

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Book Synopsis Advances in Forensic Applications of Mass Spectrometry by : Jehuda Yinon

Download or read book Advances in Forensic Applications of Mass Spectrometry written by Jehuda Yinon and published by CRC Press. This book was released on 2003-12-29 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent developments in analytical instrumentation have had an enormous influence on forensic analysis. The mass spectrometer is now an integral part of every forensic laboratory, resulting in greater analytical accuracy, more reliable identification, and lower detection limits. As the instrumental method of choice among forensic analysts, the mass

Chemometric Methods in Forensic Science

Author : Vishal Sharma
Publisher : Royal Society of Chemistry
ISBN 13 : 1839161906
Total Pages : 346 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Chemometric Methods in Forensic Science by : Vishal Sharma

Download or read book Chemometric Methods in Forensic Science written by Vishal Sharma and published by Royal Society of Chemistry. This book was released on 2023-12-20 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book fills a gap in the literature outlining how chemometric methods are applied to forensic casework, what limitations to these approaches exist, and future trends emerging in the field.

Forensic Analysis on the Cutting Edge

Author : Robert D. Blackledge
Publisher : John Wiley & Sons
ISBN 13 : 0470166908
Total Pages : 490 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis Forensic Analysis on the Cutting Edge by : Robert D. Blackledge

Download or read book Forensic Analysis on the Cutting Edge written by Robert D. Blackledge and published by John Wiley & Sons. This book was released on 2007-07-16 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title brings forensic scientists and chemists up-to-date on the latest instrumental methods for analysing trace evidence, including mass spectrometry, image analysis, DIOS-MS, ELISA characterization, statistical validation, and others. Illustrates comparative analysis of trace evidence by both old and new methods. Explains why some newer methods are superior to older, established methods. Includes chapters on analysis of DNA, ink, dyes, glitter, gun powder traces, condom trace evidence, footwear impressions, toolmark impressions, surveillance videos, glass particles, and dirt. Discusses applications such as mass spectrometry, image analysis, desorption-ionization on silicon mass spectrometry (DIOS-MS), ELISA characterization, and statistical validation.