Application of Network Theoretic Approaches in Biology

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Publisher : Frontiers Media SA
ISBN 13 : 2832531679
Total Pages : 121 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Application of Network Theoretic Approaches in Biology by : Rinku Sharma

Download or read book Application of Network Theoretic Approaches in Biology written by Rinku Sharma and published by Frontiers Media SA. This book was released on 2023-08-25 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biological complexity essentially includes and involves processes that are mediated through explicitly non-linear interactions that are often typically entangled in nature. These comprise a myriad of interactions among a vast number of entities such as genes, proteins, metabolites, and species, widely varying in scale. These interactions render biological systems across spatial and temporal scales as complex adaptive systems having features like: self-organisation, modularity, emergence, non-linear interactions, collective response and adaptation. The theory of complex networks offers an appropriate formal framework for modelling such complex systems. The enormous wealth of biological data generated by high-throughput techniques, as also through empirical investigations can be analysed using the aforementioned formal framework to obtain important insights into biological complexity.The concept of networks can be used:1) to explore the relationships between entities resulting in network generation; 2) to guide the analytic procedure based on existing network(s) as prior knowledge; and 3) to analyze the prior network(s) regarding their topology and attributes. Complex networks, being ubiquitous, permeate the biological systems across spatial and temporal scales. The objective of this collection is to highlight some very salient features of such inherent complexity in biological systems by adopting a network theoretic perspective. The anticipated pay-off is obtaining a deeper insight explicitly into the systems-level interactions and the emergent complex behaviour of the systems. Also, investigating the propulsive forces which lend various networks with akin topological characteristics that would help to merge vivid information related to various molecular interactions into a single framework, thereby permitting a structural perspective of the cellular dynamics.The application may include – exploring the disease/environmental stress response and trait mechanism using different omics platforms, candidate gene discovery and validation, network-guided discovery and deployment of omics approaches in biology; modern genetic improvement methods for delivering genes in addition to high throughput and precise phenotyping methodologies, exploring the disease/environmental stress response mechanism, marker re-prioritization, network-guided biomarker discovery etc.

Biological Network Analysis

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Author :
Publisher : Elsevier
ISBN 13 : 0128193514
Total Pages : 212 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Biological Network Analysis by : Pietro Hiram Guzzi

Download or read book Biological Network Analysis written by Pietro Hiram Guzzi and published by Elsevier. This book was released on 2020-05-11 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Network Analysis: Trends, Approaches, Graph Theory, and Algorithms considers three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN), and Human Brain Connectomes. The book's authors discuss various graph theoretic and data analytics approaches used to analyze these networks with respect to available tools, technologies, standards, algorithms and databases for generating, representing and analyzing graphical data. As a wide variety of algorithms have been developed to analyze and compare networks, this book is a timely resource. Presents recent advances in biological network analysis, combining Graph Theory, Graph Analysis, and various network models Discusses three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN) and Human Brain Connectomes Includes a discussion of various graph theoretic and data analytics approaches

An Introduction to Systems Biology

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Publisher : CRC Press
ISBN 13 : 1000001326
Total Pages : 324 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis An Introduction to Systems Biology by : Uri Alon

Download or read book An Introduction to Systems Biology written by Uri Alon and published by CRC Press. This book was released on 2019-07-12 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the first edition: ... superb, beautifully written and organized work that takes an engineering approach to systems biology. Alon provides nicely written appendices to explain the basic mathematical and biological concepts clearly and succinctly without interfering with the main text. He starts with a mathematical description of transcriptional activation and then describes some basic transcription-network motifs (patterns) that can be combined to form larger networks. – Nature [This text deserves] serious attention from any quantitative scientist who hopes to learn about modern biology ... It assumes no prior knowledge of or even interest in biology ... One final aspect that must be mentioned is the wonderful set of exercises that accompany each chapter. ... Alon’s book should become a standard part of the training of graduate students. – Physics Today Written for students and researchers, the second edition of this best-selling textbook continues to offer a clear presentation of design principles that govern the structure and behavior of biological systems. It highlights simple, recurring circuit elements that make up the regulation of cells and tissues. Rigorously classroom-tested, this edition includes new chapters on exciting advances made in the last decade. Features: Includes seven new chapters The new edition has 189 exercises, the previous edition had 66 Offers new examples relevant to human physiology and disease

Computational Network Theory

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Publisher : John Wiley & Sons
ISBN 13 : 3527337245
Total Pages : 278 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Computational Network Theory by : Matthias Dehmer

Download or read book Computational Network Theory written by Matthias Dehmer and published by John Wiley & Sons. This book was released on 2015-11-16 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive introduction to computational network theory as a branch of network theory builds on the understanding that such networks are a tool to derive or verify hypotheses by applying computational techniques to large scale network data. The highly experienced team of editors and high-profile authors from around the world present and explain a number of methods that are representative of computational network theory, derived from graph theory, as well as computational and statistical techniques. With its coherent structure and homogenous style, this reference is equally suitable for courses on computational networks.

Networks in Cell Biology

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Publisher : Cambridge University Press
ISBN 13 : 0521882737
Total Pages : 282 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Networks in Cell Biology by : Mark Buchanan

Download or read book Networks in Cell Biology written by Mark Buchanan and published by Cambridge University Press. This book was released on 2010-05-13 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Key introductory text for graduate students and researchers in physics, biology and biochemistry.

Computational Network Analysis with R

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Publisher : John Wiley & Sons
ISBN 13 : 3527339582
Total Pages : 364 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Computational Network Analysis with R by : Matthias Dehmer

Download or read book Computational Network Analysis with R written by Matthias Dehmer and published by John Wiley & Sons. This book was released on 2016-12-12 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new title in the well-established "Quantitative Network Biology" series includes innovative and existing methods for analyzing network data in such areas as network biology and chemoinformatics. With its easy-to-follow introduction to the theoretical background and application-oriented chapters, the book demonstrates that R is a powerful language for statistically analyzing networks and for solving such large-scale phenomena as network sampling and bootstrapping. Written by editors and authors with an excellent track record in the field, this is the ultimate reference for R in Network Analysis.

Network Biology

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Publisher : Nova Science Publishers
ISBN 13 : 9781626189423
Total Pages : 0 pages
Book Rating : 4.1/5 (894 download)

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Book Synopsis Network Biology by : WenJun Zhang

Download or read book Network Biology written by WenJun Zhang and published by Nova Science Publishers. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological network analysis is a fast moving science. Many core scientific issues; for example, ecological structure, coevolution, coextinction and biodiversity conservation in ecology, cancer development and metabolic regulation in health science, etc., are expected to be addressed by network analysis. Network analysis is becoming the core methodology to treat complex biological systems. With the quick development of this science, more and more papers on biological networks are published. This book includes such theories and methods of network biology as methodology of social network analyses, construction of statistic networks, phylogenetic networks, multi-stable and oscillatory biological networks, creation of real networks with expected degree distribution, forest ecosystem model, etc. Chapters are contributed by 15 scientists from the USA, Canada, New Zealand, China, Sweden, and Spain, in the areas of computational science and life sciences. It will provide researchers with various aspects of the latest advances in network biology. It is a valuable reference for scientists, university teachers and graduate students in biology, health science, ecology, social science, applied mathematics and computational science.

Handbook on Biological Networks

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Publisher : World Scientific
ISBN 13 : 9812838791
Total Pages : 465 pages
Book Rating : 4.8/5 (128 download)

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Book Synopsis Handbook on Biological Networks by : Stefano Boccaletti

Download or read book Handbook on Biological Networks written by Stefano Boccaletti and published by World Scientific. This book was released on 2010 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Networked systems are all around us. The accumulated evidence of systems as complex as a cell cannot be fully understood by studying only their isolated constituents, giving rise to a new area of interest in research ? the study of complex networks. In a broad sense, biological networks have been one of the most studied networks, and the field has benefited from many important contributions. By understanding and modeling the structure of a biological network, a better perception of its dynamical and functional behavior is to be expected. This unique book compiles the most relevant results and novel insights provided by network theory in the biological sciences, ranging from the structure and dynamics of the brain to cellular and protein networks and to population-level biology.

Networks of Networks in Biology

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Publisher : Cambridge University Press
ISBN 13 : 1108428878
Total Pages : 215 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Networks of Networks in Biology by : Narsis A. Kiani

Download or read book Networks of Networks in Biology written by Narsis A. Kiani and published by Cambridge University Press. This book was released on 2021-04 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces network inspired approaches for the analysis and integration of large, heterogeneous data sets in the life sciences.

Fundamentals Of Network Biology

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Publisher : World Scientific
ISBN 13 : 1786345102
Total Pages : 568 pages
Book Rating : 4.7/5 (863 download)

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Book Synopsis Fundamentals Of Network Biology by : Wenjun Zhang

Download or read book Fundamentals Of Network Biology written by Wenjun Zhang and published by World Scientific. This book was released on 2018-05-18 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the first comprehensive title on network biology, this book covers a wide range of subjects including scientific fundamentals (graphs, networks, etc) of network biology, construction and analysis of biological networks, methods for identifying crucial nodes in biological networks, link prediction, flow analysis, network dynamics, evolution, simulation and control, ecological networks, social networks, molecular and cellular networks, network pharmacology and network toxicology, big data analytics, and more.Across 12 parts and 26 chapters, with Matlab codes provided for most models and algorithms, this self-contained title provides an in-depth and complete insight on network biology. It is a valuable read for high-level undergraduates and postgraduates in the areas of biology, ecology, environmental sciences, medical science, computational science, applied mathematics, and social science.

Networks: From Biology to Theory

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Publisher : Springer Science & Business Media
ISBN 13 : 1846287804
Total Pages : 328 pages
Book Rating : 4.8/5 (462 download)

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Book Synopsis Networks: From Biology to Theory by : Jianfeng Feng

Download or read book Networks: From Biology to Theory written by Jianfeng Feng and published by Springer Science & Business Media. This book was released on 2007-09-04 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent decades have witnessed the thriving development of new mathematical, computational and theoretical approaches, such as bioinformatics and neuroinformatics, to tackle fundamental issues in biology. These approaches focus no longer on individual units, such as nerve cells or genes, but rather on dynamic patterns of interactions between them. This volume explores the concept in full, featuring contributions from a global group of contributors, many of whom are pre-eminent in their field.

Towards an Information Theory of Complex Networks

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Publisher : Springer Science & Business Media
ISBN 13 : 0817649042
Total Pages : 409 pages
Book Rating : 4.8/5 (176 download)

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Book Synopsis Towards an Information Theory of Complex Networks by : Matthias Dehmer

Download or read book Towards an Information Theory of Complex Networks written by Matthias Dehmer and published by Springer Science & Business Media. This book was released on 2011-08-26 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over a decade, complex networks have steadily grown as an important tool across a broad array of academic disciplines, with applications ranging from physics to social media. A tightly organized collection of carefully-selected papers on the subject, Towards an Information Theory of Complex Networks: Statistical Methods and Applications presents theoretical and practical results about information-theoretic and statistical models of complex networks in the natural sciences and humanities. The book's major goal is to advocate and promote a combination of graph-theoretic, information-theoretic, and statistical methods as a way to better understand and characterize real-world networks. This volume is the first to present a self-contained, comprehensive overview of information-theoretic models of complex networks with an emphasis on applications. As such, it marks a first step toward establishing advanced statistical information theory as a unified theoretical basis of complex networks for all scientific disciplines and can serve as a valuable resource for a diverse audience of advanced students and professional scientists. While it is primarily intended as a reference for research, the book could also be a useful supplemental graduate text in courses related to information science, graph theory, machine learning, and computational biology, among others.

Biological Network Analysis

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Author :
Publisher : Academic Press
ISBN 13 : 0128193506
Total Pages : 210 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Biological Network Analysis by : Pietro Hiram Guzzi

Download or read book Biological Network Analysis written by Pietro Hiram Guzzi and published by Academic Press. This book was released on 2020-05-26 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Network Analysis: Trends, Approaches, Graph Theory, and Algorithms considers three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN), and Human Brain Connectomes. The book's authors discuss various graph theoretic and data analytics approaches used to analyze these networks with respect to available tools, technologies, standards, algorithms and databases for generating, representing and analyzing graphical data. As a wide variety of algorithms have been developed to analyze and compare networks, this book is a timely resource. Presents recent advances in biological network analysis, combining Graph Theory, Graph Analysis, and various network models Discusses three major biological networks, including Gene Regulatory Networks (GRN), Protein-Protein Interaction Networks (PPIN) and Human Brain Connectomes Includes a discussion of various graph theoretic and data analytics approaches

Analyzing Network Data in Biology and Medicine

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Publisher : Cambridge University Press
ISBN 13 : 1108432239
Total Pages : 647 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Analyzing Network Data in Biology and Medicine by : Nataša Pržulj

Download or read book Analyzing Network Data in Biology and Medicine written by Nataša Pržulj and published by Cambridge University Press. This book was released on 2019-03-28 with total page 647 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces biological concepts and biotechnologies producing the data, graph and network theory, cluster analysis and machine learning, using real-world biological and medical examples.

Network Biology

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Publisher : Humana Press
ISBN 13 : 9781617792755
Total Pages : 0 pages
Book Rating : 4.7/5 (927 download)

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Book Synopsis Network Biology by : Gerard Cagney

Download or read book Network Biology written by Gerard Cagney and published by Humana Press. This book was released on 2011-09-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: While extremely large datasets describing gene sequences, mRNA transcripts, protein abundance, and metabolite concentrations are increasingly commonplace, these represent only starting ‘parts lists’ that are usually insufficient to unlock mechanistic insights on their own right. Fortunately, as Network Biology: Methods and Applications examines, concepts emerging from the study of biological entities such as networks (e.g. functional interactions linking genes, proteins, metabolites, etc.) suggest that order rather than chaos prevails, with such principles as modular and hierarchical organization, reactive information-driven causal-response behaviours, systems robustness, co-evolution, and self-organization guiding the way. This volume presents detailed, practical descriptions of the experimental and computational approaches currently prevalent in network biology as written by practiced experts in the field. Written in the highly successful Methods in Molecular BiologyTM series format, relevant chapters contain introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and accessible, Network Biology: Methods and Applications provides an ensemble of procedures that will be of great value to a broad assortment of readers, ranging from graduate students to seasoned professionals looking to polish their skill sets.

Analysis of Biological Networks

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Publisher : John Wiley & Sons
ISBN 13 : 1118209915
Total Pages : 278 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Analysis of Biological Networks by : Björn H. Junker

Download or read book Analysis of Biological Networks written by Björn H. Junker and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to biological networks and methods for their analysis Analysis of Biological Networks is the first book of its kind to provide readers with a comprehensive introduction to the structural analysis of biological networks at the interface of biology and computer science. The book begins with a brief overview of biological networks and graph theory/graph algorithms and goes on to explore: global network properties, network centralities, network motifs, network clustering, Petri nets, signal transduction and gene regulation networks, protein interaction networks, metabolic networks, phylogenetic networks, ecological networks, and correlation networks. Analysis of Biological Networks is a self-contained introduction to this important research topic, assumes no expert knowledge in computer science or biology, and is accessible to professionals and students alike. Each chapter concludes with a summary of main points and with exercises for readers to test their understanding of the material presented. Additionally, an FTP site with links to author-provided data for the book is available for deeper study. This book is suitable as a resource for researchers in computer science, biology, bioinformatics, advanced biochemistry, and the life sciences, and also serves as an ideal reference text for graduate-level courses in bioinformatics and biological research.

Biomolecular Networks

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Publisher : John Wiley & Sons
ISBN 13 : 9780470488058
Total Pages : 416 pages
Book Rating : 4.4/5 (88 download)

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Book Synopsis Biomolecular Networks by : Luonan Chen

Download or read book Biomolecular Networks written by Luonan Chen and published by John Wiley & Sons. This book was released on 2009-06-29 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alternative techniques and tools for analyzing biomolecular networks With the recent rapid advances in molecular biology, high-throughput experimental methods have resulted in enormous amounts of data that can be used to study biomolecular networks in living organisms. With this development has come recognition of the fact that a complicated living organism cannot be fully understood by merely analyzing individual components. Rather, it is the interactions of components or biomolecular networks that are ultimately responsible for an organism's form and function. This book addresses the important need for a new set of computational tools to reveal essential biological mechanisms from a systems biology approach. Readers will get comprehensive coverage of analyzing biomolecular networks in cellular systems based on available experimental data with an emphasis on the aspects of network, system, integration, and engineering. Each topic is treated in depth with specific biological problems and novel computational methods: GENE NETWORKS—Transcriptional regulation; reconstruction of gene regulatory networks; and inference of transcriptional regulatory networks PROTEIN INTERACTION NETWORKS—Prediction of protein-protein interactions; topological structure of biomolecular networks; alignment of biomolecular networks; and network-based prediction of protein function METABOLIC NETWORKS AND SIGNALING NETWORKS—Analysis, reconstruction, and applications of metabolic networks; modeling and inference of signaling networks; and other topics and new trends In addition to theoretical results and methods, many computational software tools are referenced and available from the authors' Web sites. Biomolecular Networks is an indispensable reference for researchers and graduate students in bioinformatics, computational biology, systems biology, computer science, and applied mathematics.