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Antigen And Antibody Molecular Engineering In Breast Cancer Diagnosis And Treatment
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Book Synopsis Antigen and Antibody Molecular Engineering in Breast Cancer Diagnosis and Treatment by : Roberto L. Ceriani
Download or read book Antigen and Antibody Molecular Engineering in Breast Cancer Diagnosis and Treatment written by Roberto L. Ceriani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today, advances in the area of immunology and breast cancer are made at an increasing rate, yielding an amount of information that can become unwieldy. The opportunity for scientists in this area of research to gather together to exchange results and working hypotheses represents, in my belief, a very attractive proposition. With this in mind, these workshops have been convened with two year intervals for the last ten years. In each of them, selected topics have been highlighted. The present workshop underscores the large advancements made in the molecular biology of both breast cancer associated antigens and their corresponding antibodies. Understanding the genetic information for the expression of these antigens has been recently advanced leading to preparation of molecularly engineered reagents for use in vaccination, serum assays, and immunizations for novel antibody production. In the anti-breast cancer antibody field the availability of molecular engineering approaches to humanize murine antibodies has induced intense interest in the creation of less immunogenic antibody forms that are now available for clinical testing. Clinical studies using anti-breast murine antibody continue to be carried out and are presented at this meeting establishing a base line for safety and efficaciousness in imaging and immunotherapy that it is hoped will be superseded by the humanized forms. Basic immunology and immunochemistry studies in breast cancer are also included in this workshop that demonstrate the fast pace at which this research is advancing in many laboratories worldwide.
Book Synopsis Bio-Engineering Approaches to Cancer Diagnosis and Treatment by : Azadeh Shahidian
Download or read book Bio-Engineering Approaches to Cancer Diagnosis and Treatment written by Azadeh Shahidian and published by Academic Press. This book was released on 2020-05-14 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioengineering Approaches to Cancer Diagnosis and Treatment is written for an audience of senior undergraduate students and graduate students in mechanical, electrical and biomedical engineering fields and other professionals in medicine. It is ideally structured for teaching and for those who are working in cancer bioengineering or interdisciplinary projects. The book's authors bring a unique perspective from their expertise in immunology, nanobiomaterials and heat transfer. Topical coverage includes an introduction to the fundamentals of bioengineering and engineering approaches for cancer diagnosis, cancer treatment via case studies, and sections on imaging, immunotherapy, cell therapy, drug delivery, ultrasound and microfluidics in cancer treatment. - Provides fully supported case studies relating to cancer diagnosis and therapy - Pairs the basic fundamentals of engineering and biomedical engineering and applies them to the diagnosis of cancer
Book Synopsis Cancer Therapy with Radiolabeled Antibodies by : David M. Goldenberg
Download or read book Cancer Therapy with Radiolabeled Antibodies written by David M. Goldenberg and published by CRC Press. This book was released on 2018-01-18 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Therapy with Radiolabeled Antibodies explores the most current experimental and clinical advances in the newly emerging field of cancer radioimmunotherapy (RAIT). Providing a multidisciplinary and international context, some of the world's leading experts examine the problems and prospects of RAIT from radiation, immunological, chemical, physical, physiological, and clinical perspectives with both overviews and original research. Discussions cover the up-to-date clinical results in the RAIT of ovarian, breast, colorectal, and brain cancers, as well as the current status of RAIT in the management of B cell lymphomas. Radiobiology, dosimetry, radiochemistry, targeting biology in experimental models, clinical experiences in hematopoietic and solid tumors, and new approaches to improve cancer radioimmunotherapy are also discussed. In addition, new dosimetry concepts, new labeling methods, new concepts of antibody pharmacokinetics, and new methods to enhance selective cancer radioimmunotherapy are included.
Book Synopsis Applications And Engineering Of Monoclonal Antibodies by : David J. King
Download or read book Applications And Engineering Of Monoclonal Antibodies written by David J. King and published by CRC Press. This book was released on 1998-11-27 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: A valuable resource for researchers and workers in the fields of both pharmaceuticals and biotechnology as well as undergraduates in biochemistry, applied biology, biomedical sciences and pharmacy, this book compares established techniques of antibody production with the new. Antibody structure and the implications of antibody engineering are fully discussed, and a case study approach illustrates how antibodies are finding increasing use in the diagnosis and treatment of disease. The volume ends with commercial expression, purification and large-scale manufacture of antibodies and their future potential, particularly as therapeutic agents.
Book Synopsis Monoclonal Antibodies by : Heddy Zola
Download or read book Monoclonal Antibodies written by Heddy Zola and published by Garland Science. This book was released on 2020-08-26 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of what needs to be done to realise the potential of monoclonal antibodies. The book assesses the competing technologies with advice on the best approach for a particular situation.
Book Synopsis Breast Cancer Advances in Biology and Therapeutics by : Henri Magdelenat
Download or read book Breast Cancer Advances in Biology and Therapeutics written by Henri Magdelenat and published by John Libbey Eurotext. This book was released on 1996 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contributions from leading authors in the field of clinical and biological breast cancer research constitute these three chapters: predisposition to breast cancer, carcinogenesis, and early breast cancer screening and management; tumour biology and prognostic; and therapeutics aspects of breast cancer. 21st Meeting of the International Association for Breast Cancer Research, Paris, 1996.
Book Synopsis Radioimmunotherapy of Cancer by : Paul G. Abrams
Download or read book Radioimmunotherapy of Cancer written by Paul G. Abrams and published by CRC Press. This book was released on 2000-07-11 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reflecting the past 20 years of intense research in radioimmunotherapy, this timely reference surveys an expansive breadth of topics on the evolving developments in radiation therapy. Placed in the context of advances in cancer treatment, chapters progress systematically from basic principles and properties of radionuclides to detailed summaries of
Book Synopsis Handbook of Cancer Vaccines by : Michael A. Morse
Download or read book Handbook of Cancer Vaccines written by Michael A. Morse and published by Springer Science & Business Media. This book was released on 2004-01-28 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative survey of the scientific background for therapeutic cancer vaccines, the challenges to their development, and their current uses in treating cancer. The authors examine the basic issues that effect all vaccines (such as immune adjuvants and prime-boost strategies), describe the methods for antigen discovery, and review the preclinical development phases for each major vaccine strategy. They also spell out the clinical results for cancer vaccines now beginning to be used in the treatment of many common cancers.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1988 with total page 1632 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ovarian Cancer written by Samir Farghaly and published by BoD – Books on Demand. This book was released on 2012-02-15 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Worldwide, Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined. International leaders in the field address the critical biologic and basic science issues relevant to the disease. The book details the molecular biological aspects of ovarian cancer. It provides molecular biology techniques of understanding this cancer. The techniques are designed to determine tumor genetics, expression, and protein function, and to elucidate the genetic mechanisms by which gene and immunotherapies may be perfected. It provides an analysis of current research into aspects of malignant transformation, growth control, and metastasis. A comprehensive spectrum of topics is covered providing up to date information on scientific discoveries and management considerations.
Book Synopsis Monoclonal Antibodies by : Philip Shepherd
Download or read book Monoclonal Antibodies written by Philip Shepherd and published by Oxford University Press, USA. This book was released on 2000 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monoclonal Antibodies: A Practical Approach covers the preparation, testing, derivation, and applications of monoclonal antibodies. New immunological techniques incorporating tried and tested methodologies are described, making the book of interest to established and inexperienced immunologists. Both the standard somatic hybridization technique and recombinant techniques, including the use of phage libraries, for the preparation of rodent and human monoclonal antibodies are described. Protocols for both the small and large scale production are detailed, as well as purification and labelling (with both radioisotopes and non-radioisotopes) methods. The applications of monoclonal antibodies in immunoblotting, enzyme linked immunoassays, immunofluorescence, and FACS analysis are all covered in detail. Finally protocols are given for the use of monoclonal antibodies in rheumatoid arthritis, tissue typing, detecting DNA modified during chemotherapy, and in the clinical analysis of transplantation samples for malignancy. This book will therefore be an invaluable laboratory companion to anyone using monoclonal antibodies in their research.
Book Synopsis Diet and Cancer by : Maryce M. Jacobs
Download or read book Diet and Cancer written by Maryce M. Jacobs and published by Springer Science & Business Media. This book was released on 2013-11-22 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Institute for Cancer Research (AICR) sponsored its third annual confer ence on nutrition and cancer. The theme was "Diet and Cancer: Markers, Prevention, and Treatment. " The conference was held October 29-30, 1992 at the Ritz Carlton Hotel in McLean, Virginia. This proceedings contains chapters from the platform presentations and abstracts from the poster presentations. Several chapters address each of four session topics: Retinoids as Differentiation Agents in Cancer Therapy, Biological Markers of Cancer Risk, Chemoprevention of Cancer by Non-Nutrients in Foods, and Nutritional Problems and Support in the Treatment of Cancer. The first three chapters discuss in detail different mechanisms by which retinoids influence differentiation and provide evidence to support their use in cancer therapy. In vivo and in vitro studies show the effects of retinoic acid (RA) on tumorigenicity and cellu lar/molecular events. A synopsis of data showing the involvement of the retinoblastoma (RB) gene in HL-60 cell differentiation induced by RA and 1,2S-dihydroxy vitamin D3 (VD) is presented. In SCID (severe combined immunodeficiency) mice injected with HL-60 3 human leukemia cells and gavaged daily with RA, the number of tumor sites and number of mice with tumors are reduced. All trans-RA induces myeloid differentiation in HL-60 cells. Similarly, VD3 induces HL-60 monocytic differentiation. In both cases an early down regulation of retinoblastoma (RB) gene expression precedes the differentiation.
Download or read book Actin written by James E. Estes and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the period August 5-9, 1992, and immediately preceding the 1992 Gordon Research Conference on Motile and Contractile Systems, the "Third International Conference on the Structure and Function of Ubiquitous Cellular Protein Actin" was held at the Emma Willard School in Troy, New York, under the title "ACTIN '92". This conference focused on the fundamental properties and cellular functions of actin and actin based microfilament systems. The first conference in this series was held in 1982, in Sydney, Australia, and hosted by Dr. Cristobal G. dos Remedios and Dr. Julian A. Barden, both from the University of Sydney (New South Wales, Austrailia). The second conference convened in Monza, Italy in June 1987, and was organized by Dr. Roberto Colombo, University of Milan (Italy). This third gathering of researchers devoted to the study of actin and actin-associated proteins was organized by Dr. James E. Estes, Albany Stratton V A Medical Center and Dr. Paul 1. Higgins, Albany Medical College, who were assisted by an Organizing Committee consisting of Dr. Edward D. Korn (National Heart, Lung and Blood Institute, NIH), Dr. Thomas P. Stossel (Massachusetts General Hospital), Dr. Fumio Matsumura (Rutgers University), and Dr. Stephen Farmer (Boston University). This meeting was dedicated to the many pioneering contributions of Professor Fumio Oosawa to the field of actin research.
Book Synopsis Progress in Iron Research by : Chaim Hershko
Download or read book Progress in Iron Research written by Chaim Hershko and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 4th International Conference on Hemochromatosis and the 11th International Conference on Iron and Iron Proteins took place in Jerusalem on April 27 -30 and on May 2 -7 1993, respectively. The first, a clinical meeting, and the second, a forum designed primarily for basic scientists. Both meetings are held regularly on alter nate years and represent probably the most important forum for the exchange of information in iron research. The present volume "Progress in Iron Research" is based on a selection of presentations delivered at these meetings. However, this volume represents much more than a publication of conference proceedings. It offers a comprehensive state-of-the-art review on most aspects of iron metabolism. We have tried to offer a balanced review of the most important recent developments in iron research including both basic research and clinical investigation. However, the scope of chapters was based, by definition, on the actual participants at the meetings and some important fields in iron research such as plant physiology, microbial aspects of iron metabolism, and free radical research have not been dealt with. Many of the authors of the 40 chapters have beel). pt1rsonally responsible for some of the most important developments in iron research ~~vidffig: n~~~ights into iron physiology and pathophysiology. The Editors wish to express their gratitude for the outstanding and timely cooperation of all contributors to this volume.
Book Synopsis Arterial Chemoreceptors by : Ronan G. O'Regan
Download or read book Arterial Chemoreceptors written by Ronan G. O'Regan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Society for Arterial Chemoreception (ISAC) was founded in August 1988 during the 9th International Symposium on Arterial Chemoreception which was held at Park City, Utah, USA. ISAC was established with the aim of providing a framework to support the increasing number of investigators from a wide variety of disciplines (anatomists, pathologists, respiratory physiologists and clinicians, high altitude physiologists, biochemists, biophysicists, physiologists and pharmacologists) who share a common interest in arterial chemoreception. ISAC took over the co-ordination of the international chemoreceptor meetings, with the membership deciding the venue for forthcoming meetings. During the Park City symposium Dublin was selected to host the 1993 meeting, under the Presidency of Professor Ronan O'Regan. The 12th International Meeting on Arterial Chemoreception, which was held in Dublin in August 1993, was acclaimed as a great success by all those present. The delegates not only shared in a wide-ranging feast of chemoreceptor based science, they had plenty of opportunity during the meeting for renewing acquaintances and establishing new friendships. The location for the meeting at University College Dublin's modem Belfield campus helped to promote such interaction, and the social programme was outstanding.
Download or read book In Vivo Immunology written by E. Heinen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 11th International Conference on Lymphoid Tissues and Immune Reactions was held in Spa-Liege (Belgium), from 4 to 8 July 1993. The regular devotees refer to these conferences as the "Germinal Centre Conferences or GCC". In the 1960s, the germinal centres were the subject of such considerable study and speculation that a group of dynamic people decided to devote an international conference centered on that topic. This led to the fIrst GCC organized in Bern in 1966. Following the success of this initial meeting, further sessions have been organized at regular intervals and, over the years, the scope of the GCC has been broadened. Nowadays, the GCC conferences are dedicated to in vivo immunology and deal mainly with cellular, functional and molecular aspects of the lymphoid system. The credo of these conferences is "in vivo veritas," implying that the sole investigation of components (like molecules or cell populations) only gives a partial truth. Ultimately, the components have to be explored in their global context in order to see how they interact with other parts and how they are integrated as a whole to ensure the homeostasis of the immune system. In 1966, the GCC lasted 3 days and included 57 contributions "which were discussed at length. " The present conference lasted 4 days and accommodated 2 honorary lectures, 80 free papers and 209 poster presentations. Out of those presentations, a selection was performed by the Chairpersons to compose the present volume.
Book Synopsis Biomedical Index to PHS-supported Research by :
Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1991 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt:
