The New Profile of Drug-Resistant Tuberculosis in Russia

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Author :
Publisher : National Academies Press
ISBN 13 : 0309162971
Total Pages : 158 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The New Profile of Drug-Resistant Tuberculosis in Russia by : Russian Academy of Medical Sciences

Download or read book The New Profile of Drug-Resistant Tuberculosis in Russia written by Russian Academy of Medical Sciences and published by National Academies Press. This book was released on 2011-08-07 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: An estimated 2 billion people, one third of the global population, are infected with Mycobacterium tuberculosis, the bacterium that causes tuberculosis. Spread through the air, this infectious disease killed 1.7 million in 2009, and is the leading killer of people with HIV. Tuberculosis (TB) is also a disease of poverty-the vast majority of tuberculosis deaths occur in the developing world. Exacerbating the devastation caused by TB is the growing threat of drug-resistant forms of the disease in many parts of the world. Drug-resistant tuberculosis presents a number of significant challenges in terms of controlling its spread, diagnosing patients quickly and accurately, and using drugs to treat patients effectively. In Russia in recent decades, the rise of these strains of TB, resistant to standard antibiotic treatment, has been exacerbated by the occurrence of social, political, and economic upheavals. The Institute of Medicine (IOM) Forum on Drug Discovery, Development, and Translation, in conjunction with the Russian Academy of Medical Sciences held a workshop to discuss ways to fight the growing threat of drug-resistant TB. The New Profile of Drug-Resistant Tuberculosis in Russia: A Global and Local Perspective: Summary of a Joint Workshop presents information from experts on the nature of this threat and how it can be addressed by exploring various treatment and diagnostic options.

Anti-tuberculosis Drug Resistance in the World

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Author :
Publisher : World Health Organization
ISBN 13 : 9241563613
Total Pages : 143 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Anti-tuberculosis Drug Resistance in the World by : Abigail Wright

Download or read book Anti-tuberculosis Drug Resistance in the World written by Abigail Wright and published by World Health Organization. This book was released on 2008 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multidrug-resistant tuberculosis (MDR-TB) has been recorded at the highest rates ever, according to this new report that presents findings from the largest survey to date on the scale of drug resistance in tuberculosis. This fourth global report is based on information collected between 2002 and 2006 on 90,000 TB patients in 81 countries. It also found that extensively drug-resistant tuberculosis (XDR-TB), a virtually untreatable form of the respiratory disease, has been recorded in 45 countries. The primary aim of this report is to share survey and surveillance data on drug resistance in TB. The data presented here are supplied largely by the program managers who have led the work on surveys, but also heads of reference laboratories as well as principle investigators that may have been hired to assist the national Tuberculosis Program with the study.

Management of MDR-TB

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Author :
Publisher : World Health Organization
ISBN 13 : 9241547766
Total Pages : 61 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Management of MDR-TB by : World Health Organization

Download or read book Management of MDR-TB written by World Health Organization and published by World Health Organization. This book was released on 2009 with total page 61 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB) are increasingly encountered in resource-limited settings. In the context of a national response to MDR- and XDR-TB, health workers in TB clinics (in district hospitals and some accredited health centers) will need to diagnose MDR-TB, initiate second-line anti-TB drugs, and monitor MDR-TB treatment. This Field Guide was created to help health workers carry out these tasks. It is a job aid that medical officers and TB nurses are meant to use frequently during the day for quick reference. It is based on the Emergency Update 2008 of Guidelines for Programmatic Management of Drug-resistant Tuberculosis, and may be considered a companion document to these guidelines. It also draws on the experience of the international health NGO Partners In Health (PIH) in many countries. This module should be introduced to health workers in the context of a training course with a strong emphasis on TB-HIV co-management.

WHO consolidated guidelines on tuberculosis. Module 4

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Publisher : World Health Organization
ISBN 13 : 924004812X
Total Pages : 72 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis WHO consolidated guidelines on tuberculosis. Module 4 by : World Health Organization

Download or read book WHO consolidated guidelines on tuberculosis. Module 4 written by World Health Organization and published by World Health Organization. This book was released on 2022-04-30 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: Between 2011 and 2019, WHO has developed and issued evidence-based policy recommendations on the treatment and care of patients with DR-TB. These policy recommendations have been presented in several WHO documents and their associated annexes, including the WHO Consolidated Guidelines on Drug Resistant Tuberculosis Treatment, issued by WHO in March 2019. The policy recommendations in each of these guidelines have been developed by WHO-convened Guideline Development Groups, using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach to summarize the evidence, and formulate policy recommendations and accompanying remarks. The present WHO Consolidated Guidelines on Tuberculosis, Module 4: Treatment - Drug-Resistant Tuberculosis Treatment includes a comprehensive set of WHO recommendations for the treatment and care of DR-TB. The document includes two new recommendations, one on the composition of shorter regimens and one on the use of the BPaL regimen (i.e. bedaquiline, pretomanid and linezolid). In addition, the consolidated guidelines include existing recommendations on treatment regimens for isoniazid-resistant TB and MDR/RR-TB, including longer regimens, culture monitoring of patients on treatment, the timing of antiretroviral therapy (ART) in MDR/RR-TB patients infected with the human immunodeficiency virus (HIV), the use of surgery for patients receiving MDR-TB treatment, and optimal models of patient support and care. The guidelines are to be used primarily in national TB programmes, or their equivalents in Ministries of Health, and for other policy-makers and technical organizations working on TB and infectious diseases in public and private sectors and in the community.

Guidelines for the Programmatic Management of Drug-resistant Tuberculosis

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Author :
Publisher : World Health Organization
ISBN 13 : 9241547588
Total Pages : 271 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Guidelines for the Programmatic Management of Drug-resistant Tuberculosis by : World Health Organization

Download or read book Guidelines for the Programmatic Management of Drug-resistant Tuberculosis written by World Health Organization and published by World Health Organization. This book was released on 2008 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of extensively drug-resistant strains of tuberculosis, especially in countries with a high prevalence of human immunodeficiency virus, is a serious threat to global public health and jeopardizes efforts to effectively control the disease. This publication offers updated recommendations for the diagnosis and management of drug-resistant tuberculosis in a variety of geographical, economic and social settings, and the recording of data that enables the monitoring and evaluation of programs.--Publisher's description.

Guidelines for the Programmatic Management of Drug-Resistant Tuberculosis

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Author :
Publisher :
ISBN 13 : 9789241501583
Total Pages : 0 pages
Book Rating : 4.5/5 (15 download)

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Book Synopsis Guidelines for the Programmatic Management of Drug-Resistant Tuberculosis by : World Health Organization

Download or read book Guidelines for the Programmatic Management of Drug-Resistant Tuberculosis written by World Health Organization and published by . This book was released on 2015-04-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 2011 update of Guidelines for the programmatic management of drug-resistant tuberculosis is intended as a tool for use by public health professionals working in response to the Sixty-second World Health Assembly's resolution on prevention and control of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis. Resolution WHA62.15, adopted in 2009, calls on Member States to develop a comprehensive framework for the management and care of patients with drug-resistant TB. The recommendations contained in these guidelines address the most topical questions concerning the programmatic management of drug-resistant TB: case-finding, multidrug resistance, treatment regimens, monitoring the response to treatment, and selecting models of care. The guidelines primarily target staff and medical practitioners working in TB treatment and control, and partners and organizations providing technical and financial support for care of drug-resistant TB in settings where resources are limited.

Anti-tuberculosis Drug Resistance in the World

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Publisher : World Health Organization
ISBN 13 : 9789241562850
Total Pages : 306 pages
Book Rating : 4.5/5 (628 download)

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Book Synopsis Anti-tuberculosis Drug Resistance in the World by : Mohamed Abdel Aziz

Download or read book Anti-tuberculosis Drug Resistance in the World written by Mohamed Abdel Aziz and published by World Health Organization. This book was released on 2004 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the third report of the WHO/IUATLD project which gives comparable worldwide information on anti-tuberculosis drug resistance, with data from surveys conducted in 77 different countries or geographical settings during the years 1999 to 2002. Global surveillance identifies areas of high resistance and draws the attention of national authorities to address the problems involved. The report also highlights the importance of conducting surveillance on re-treatment cases, and the role of the laboratory in TB control.

Anti-tuberculosis Drug Resistance in the World

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Publisher :
ISBN 13 :
Total Pages : 226 pages
Book Rating : 4.:/5 (963 download)

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Book Synopsis Anti-tuberculosis Drug Resistance in the World by : World Health Organization

Download or read book Anti-tuberculosis Drug Resistance in the World written by World Health Organization and published by . This book was released on 1997 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Treatment of Tuberculosis

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Publisher :
ISBN 13 :
Total Pages : 60 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Treatment of Tuberculosis by : World Health Organization

Download or read book Treatment of Tuberculosis written by World Health Organization and published by . This book was released on 1993 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Timebomb:The Global Epidemic of Multi-Drug Resistant Tuberculosis

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Author :
Publisher : McGraw Hill Professional
ISBN 13 : 0071389725
Total Pages : 258 pages
Book Rating : 4.0/5 (713 download)

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Book Synopsis Timebomb:The Global Epidemic of Multi-Drug Resistant Tuberculosis by : Lee Reichman

Download or read book Timebomb:The Global Epidemic of Multi-Drug Resistant Tuberculosis written by Lee Reichman and published by McGraw Hill Professional. This book was released on 2001-11-05 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is an excellent book. It should be read by all who are interested in any aspect of Tuberculosis, including the growing problem of Multi-Drug Resistant Tuberculosis." Journal of American Medical Association "The book serves an important function, relaying statistics and TB hot spots, proposing funding and international standardized treatments. Government officials, researchers and nonprofit health organizations will likely cast this as the authoritative book on the subject." Publishers Weekly "Like other recent works on the threat of infectious diseases such as Laurie Garrett's The Coming Plague, Timebomb has the power of fiction and it is sometimes easy to forget that it is not. Unlike the Garrett book, which is more a collection of short dramatic stories collectively telling a big picture about our coexistence and evolution with microbes, Reichman selects one story and presents it in novel form with better material that most science fiction. The book is organized in a clear and riveting manner. Within the narrative style, the book is rich with up-to-the-minute details and references that add to its depth. An incredible account of politics and disease dynamics occurring at all levels, Timebomb helps us realize that controlling or eradicating TB is not just about science and facts; likely if it were, TB would have long been relegated to the history books." Nature Medicine Magazine Tuberculosis, supposedly defeated by antibiotics half a century ago, has returned in a highly contagious and fatal new form that cannot be treated with conventional drugs. Multidrug-resistant TB (MDR-TB), could cause some 10 million deaths over the next decade and is thriving in the overcrowded prisons of the former Soviet Union. As Timebomb explains in unnerving detail, the virtual collapse of the world's borders means that refugees, tourists, immigrants, business travelers, and others can spread the TB bacillus very efficiently. London, for example, has experienced a 100% increase in reported cases in the past 10 years. Written by the world's preeminent TB expert and an award-winning medical and health writer, Timebomb details the evolution and the current state of the MDR-TB epidemic, interweaving the science of MDR-TB with personal stories of people whose lives have been threatened by the deadly bacteria.

Anti-Tuberculosis Drug Resistance in the World

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Author :
Publisher :
ISBN 13 : 9780119862430
Total Pages : 253 pages
Book Rating : 4.8/5 (624 download)

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Book Synopsis Anti-Tuberculosis Drug Resistance in the World by : World Health Organisation Staff

Download or read book Anti-Tuberculosis Drug Resistance in the World written by World Health Organisation Staff and published by . This book was released on 2001-01-01 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Guidelines for the Management of Drug-resistant Tuberculosis

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Author :
Publisher :
ISBN 13 :
Total Pages : 52 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guidelines for the Management of Drug-resistant Tuberculosis by : John Crofton

Download or read book Guidelines for the Management of Drug-resistant Tuberculosis written by John Crofton and published by . This book was released on 1997 with total page 52 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Use of Bedaquiline in the Treatment of Multidrug-resistant Tuberculosis

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Publisher :
ISBN 13 : 9789241505482
Total Pages : 0 pages
Book Rating : 4.5/5 (54 download)

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Book Synopsis The Use of Bedaquiline in the Treatment of Multidrug-resistant Tuberculosis by : World Health Organization

Download or read book The Use of Bedaquiline in the Treatment of Multidrug-resistant Tuberculosis written by World Health Organization and published by . This book was released on 2015-04-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO estimates that up to half a million new cases of multidrug-resistant tuberculosis (MDR-TB) occur worldwide, each year. Current treatment regimens for MDR-TB present many challenges: treatment lasts 20 months or more, requiring daily administration of drugs that are more toxic, less effective, and far more expensive than those used to treat drug-susceptible TB. Globally, less than half of all patients who start MDR-TB therapy are treated successfully. For the first time in over 40 years, a new TB drug with a novel mechanism of action - bedaquiline- is available, and was granted accelerated approval by the United States Food and Drug Administration in December 2012. There is considerable interest in the potential of this drug to treat MDR-TB. However, information about this new drug remains limited. It has only been through two Phase IIb trials for safety and efficacy. The World Health Organization (WHO) is therefore issuing "interim policy guidance". This interim guidance provides advice on the inclusion of bedaquiline in the combination therapy of MDR-TB in accordance with the existing WHO Guidelines for the Programmatic Management of Drug-resistant TB (2011 Update).

Ethics and Drug Resistance: Collective Responsibility for Global Public Health

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Author :
Publisher : Springer
ISBN 13 : 9783030278762
Total Pages : 448 pages
Book Rating : 4.2/5 (787 download)

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Book Synopsis Ethics and Drug Resistance: Collective Responsibility for Global Public Health by : Euzebiusz Jamrozik

Download or read book Ethics and Drug Resistance: Collective Responsibility for Global Public Health written by Euzebiusz Jamrozik and published by Springer. This book was released on 2021-08-21 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open Access volume provides in-depth analysis of the wide range of ethical issues associated with drug-resistant infectious diseases. Antimicrobial resistance (AMR) is widely recognized to be one of the greatest threats to global public health in coming decades; and it has thus become a major topic of discussion among leading bioethicists and scholars from related disciplines including economics, epidemiology, law, and political theory. Topics covered in this volume include responsible use of antimicrobials; control of multi-resistant hospital-acquired infections; privacy and data collection; antibiotic use in childhood and at the end of life; agricultural and veterinary sources of resistance; resistant HIV, tuberculosis, and malaria; mandatory treatment; and trade-offs between current and future generations. As the first book focused on ethical issues associated with drug resistance, it makes a timely contribution to debates regarding practice and policy that are of crucial importance to global public health in the 21st century.

Toman's Tuberculosis

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Publisher : World Health Organization
ISBN 13 : 9241546034
Total Pages : 350 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Toman's Tuberculosis by : K. Toman

Download or read book Toman's Tuberculosis written by K. Toman and published by World Health Organization. This book was released on 2004-06-23 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second edition of a reference work aimed at all those concerned with dealing with tuberculosis control in developing countries. The book follows in the tradition of Kurt Toman's original work in this field, with the text set out in a question and answer format, grouped under three headings: case detection; treatment, and monitoring. The threat of tuberculosis is still potent, with two million deaths globally. This new edition, containing contributions from a number of experts in this field, addresses the resurgence of tuberculosis, and the emergence of multidrug-resistant bacilli, and the growth of HIV-infected individuals with tuberculosis, as well as recent scientific developments.

Guidance for National Tuberculosis Programmes on the Management of Tuberculosis in Children

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Publisher :
ISBN 13 : 9789241548748
Total Pages : 0 pages
Book Rating : 4.5/5 (487 download)

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Book Synopsis Guidance for National Tuberculosis Programmes on the Management of Tuberculosis in Children by : World Health Organization

Download or read book Guidance for National Tuberculosis Programmes on the Management of Tuberculosis in Children written by World Health Organization and published by . This book was released on 2015-02-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is estimated that one third of the world's population is infected with Mycobacterium tuberculosis (the bacterium that causes tuberculosis (TB)), and that each year, about 9 million people develop TB, of whom about 2 million die. Of the 9 million annual TB cases, about 1 million (11%) occur in children (under 15 years of age). Of these childhood cases, 75% occur annually in 22 high-burden countries that together account for 80% of the world's estimated incident cases. In countries worldwide, the reported percentage of all TB cases occurring in children varies from 3% to more than 25%. The Stop TB Strategy, which builds on the DOTS strategy developed by the World Health Organization (WHO) and the International Union Against TB and Lung Disease, has a critical role in reducing the worldwide burden of disease and thus in protecting children from infection and disease. The management of children with TB should be in line with the Stop TB Strategy, taking into consideration the particular epidemiology and clinical presentation of TB in children. These consensus guidelines were produced to help the National Tuberculosis Programmes on the management of tuberculosis in children.

Phantom Plague

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Publisher : Penguin Random House India Private Limited
ISBN 13 : 9354925758
Total Pages : 249 pages
Book Rating : 4.3/5 (549 download)

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Book Synopsis Phantom Plague by : Vidya Krishna

Download or read book Phantom Plague written by Vidya Krishna and published by Penguin Random House India Private Limited. This book was released on 2022-04-29 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive social history of tuberculosis, from its origins as a haunting mystery to its modern reemergence that now threatens populations around the world. It killed novelist George Orwell, Eleanor Roosevelt, and millions of others-rich and poor. Desmond Tutu, Amitabh Bachchan, and Nelson Mandela survived it, just. For centuries, tuberculosis has ravaged cities and plagued the human body. In Phantom Plague, Vidya Krishnan, traces the history of tuberculosis from the slums of 19th-century New York to modern Mumbai. In a narrative spanning century, Krishnan shows how superstition and folk-remedies, made way for scientific understanding of TB, such that it was controlled and cured in the West. The cure was never available to black and brown nations. And the tuberculosis bacillus showed a remarkable ability to adapt-so that at the very moment it could have been extinguished as a threat to humanity, it found a way back, aided by authoritarian government, toxic kindness of philanthropists, science denialism and medical apartheid. Krishnan's original reporting paints a granular portrait of the post-antibiotic era as a new, aggressive, drug resistant strain of TB takes over. Phantom Plague is an urgent, riveting and fascinating narrative that deftly exposes the weakest links in our battle against this ancient foe.