IgE and Anti-IgE Therapy in Asthma and Allergic Disease

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Author :
Publisher : CRC Press
ISBN 13 : 0203909003
Total Pages : 576 pages
Book Rating : 4.2/5 (39 download)

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Book Synopsis IgE and Anti-IgE Therapy in Asthma and Allergic Disease by : Robert Fick

Download or read book IgE and Anti-IgE Therapy in Asthma and Allergic Disease written by Robert Fick and published by CRC Press. This book was released on 2002-04-24 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploring the role of Immunoglobulin-E (IgE) in human disease, this reference summarizes current research on the mechanisms and utilization of anti-IgE therapeutics in the treatment of IgE-mediated allergic disease, inflammation, and asthma-discussing the structural composition of high- and low-affinity IgE receptors, the airway cells that express

Anti-IgE Therapy in Asthma and Allergy

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Author :
Publisher : CRC Press
ISBN 13 : 9781841840901
Total Pages : 64 pages
Book Rating : 4.8/5 (49 download)

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Book Synopsis Anti-IgE Therapy in Asthma and Allergy by : S.H. Arshad

Download or read book Anti-IgE Therapy in Asthma and Allergy written by S.H. Arshad and published by CRC Press. This book was released on 2001-05-10 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Little new has been introduced into the armamentarium for asthma therapy in the last thirty years apart from improvements in b2-adrenoceptor agonists, corticosteroids and cysteinyl leukotriene antagonists. However, the introduction of a fully humanised monoclonal antibody to immunoglobulin E (IgE) (omalizumab), should provide a new way of treating allergic disorders, with effects that extend beyond a single affected organ and tissue. The precise role of this new agent in treatment guidelines will need to be carefully evaluated, but its clear efficacy and safety provide a strong statement about the importance of IgE across the full spectrum of allergic disease. This pocketbook provides an illustrative summary of the role of IgE in the pathogenesis of asthma and allied allergic disorders, as well as the effects of anti-IgE therapy in the management of these conditions.

Anti-IgE Therapy for Asthma and Allergy

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Author :
Publisher :
ISBN 13 : 9780429221095
Total Pages : 67 pages
Book Rating : 4.2/5 (21 download)

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Book Synopsis Anti-IgE Therapy for Asthma and Allergy by :

Download or read book Anti-IgE Therapy for Asthma and Allergy written by and published by . This book was released on 2001 with total page 67 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Severe Asthma

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Author :
Publisher : European Respiratory Society
ISBN 13 : 1849841047
Total Pages : 360 pages
Book Rating : 4.8/5 (498 download)

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Book Synopsis Severe Asthma by : Kian Fan Chung

Download or read book Severe Asthma written by Kian Fan Chung and published by European Respiratory Society. This book was released on 2019-06-01 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.

Urticaria and Angioedema

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 9535131672
Total Pages : 252 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Urticaria and Angioedema by : Selda Pelin Kartal

Download or read book Urticaria and Angioedema written by Selda Pelin Kartal and published by BoD – Books on Demand. This book was released on 2017-05-31 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the latest advances and scientific knowledge from the leading experts in urticaria and angioedema. The book consists of 15 chapters in which urticaria classification, urticaria etiopathogenesis, urticaria clinics, urticarial syndromes, angioedemas, diagnosis, pathogenesis and pathophysiology of urticaria, and treatment options are discussed. This book also emphasizes on the various laboratory tests necessary for urticarias. One chapter of the book is devoted to comorbidities in chronic spontaneous urticaria. Another chapter is related with pathophysiology and treatment of hereditary angioedema. We are grateful to all the contributors and leading experts for their valuable chapters, which provide an in-depth view of all aspects of the content, backed with the most current literature in the field. We hope that this book will provide interesting knowledge and serve as a comprehensive guide to many physicians dealing with urticaria and angioedemas in their clinical practice.

Hepatotoxicity

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781719520
Total Pages : 848 pages
Book Rating : 4.7/5 (195 download)

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Book Synopsis Hepatotoxicity by : Hyman J. Zimmerman

Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

New and Exploratory Therapeutic Agents for Asthma

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Author :
Publisher : CRC Press
ISBN 13 : 0824746813
Total Pages : 549 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis New and Exploratory Therapeutic Agents for Asthma by : Michael Yeadon

Download or read book New and Exploratory Therapeutic Agents for Asthma written by Michael Yeadon and published by CRC Press. This book was released on 1999-11-12 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses three major classes of asthma therapies-bronchodilators, antiinflammatories, and antiallergics-as well as potential new therapeutic approaches! This comprehensive volume addresses the latest treatment strategies for asthma, keying in on the genetics and molecular biology of asthma and pointing the way toward new, commercially viable therapies. Presents the most up-to-date information available on the genetics, epidemiology, pathology, pharmacology, and pulmonology of asthma. Written by more than 20 leading international experts, New and Exploratory Therapeutic Agents for Asthma explores asthma both as incidence of dysfunctional airway smooth muscle and as a disorder of the immune system examines the role of monoclonal antibodies in allergy and asthma describes functions and pharmacokinetic profiles of bronchodilator 2 agonists, anticholinergics, and inhaled glucocorticosteroids investigates the controversy of different types of asthma illustrates the connections between clinical symptoms and the immunopathology of eosinophilic inflammation assesses prospects for the development of a successful oral anti-inflammatory therapy, an immunomodulator that lowers antigen-specific IgE, an anticytokine compound, and an agent that safely combines bronchospasmolytic and anti-inflammatory properties reviews the impact of the recent introduction of antileukotriene agents, clinical findings with PAF antagonists, and selective antimuscarinics evaluates the relationship between improvements in laboratory results and clinical effectiveness and more! Containing over 2000 bibliographic citations and a concise introduction for each chapter, New and Exploratory Therapeutic Agents for Asthma is indispensable for pulmonologists, pediatricians, physiologists, immunologists, allergists, pharmaceutical industry scientists, primary care physicians, and medical school students in these disciplines.

Signal Transduction in Mast Cells and Basophils

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Publisher : Springer Science & Business Media
ISBN 13 : 9780387986258
Total Pages : 454 pages
Book Rating : 4.9/5 (862 download)

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Book Synopsis Signal Transduction in Mast Cells and Basophils by : Ehud Razin

Download or read book Signal Transduction in Mast Cells and Basophils written by Ehud Razin and published by Springer Science & Business Media. This book was released on 1999-05-11 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mast cells and basophils are responsible for inflammatory and allergic reactions. As such, the signals that generate these responses and how their pathways of action work are the focus of much present day research into allergy and inflammation. This book focuses primarily on the molecular mechanisms that govern mast cell and basophil cell biology and function, as well as providing a comprehensive summary of the field of signal transduction and also giving insights into areas that have therapeutic potential. The book provides detailed insights into mast cell and basophil growth and development, their activation by allergens, including details of receptor activation and downstream events, and the regulators of morphology and degranulation. The metabolic pathways involved in prostaglandin and leukotriene production are discussed as is the role of transcription factors in mast cell growth and cytokine production. Written by leaders in the field, this volume will provide the reader with an up-to-date account of a topic where the rapid progress makes conventional information gathering difficult.

Janeway's Immunobiology

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Author :
Publisher : Garland Science
ISBN 13 : 9780815344575
Total Pages : pages
Book Rating : 4.3/5 (445 download)

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Book Synopsis Janeway's Immunobiology by : Kenneth Murphy

Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Asthma

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Publisher : Oxford University Press, USA
ISBN 13 : 0199918066
Total Pages : 513 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Asthma by : Richard F. Lockey

Download or read book Asthma written by Richard F. Lockey and published by Oxford University Press, USA. This book was released on 2014 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosing asthma requires knowledge of the multiple conditions that emulate it, and treatment requires addressing factors that modify the disease. This comprehensive, single reference will help practitioners identify and care for co-morbid conditions and improve asthma treatment.

Diagnosis and Management of Asthma

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Publisher : Professional Communications
ISBN 13 : 1932610383
Total Pages : 289 pages
Book Rating : 4.9/5 (326 download)

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Book Synopsis Diagnosis and Management of Asthma by : Mani S. Kavuru

Download or read book Diagnosis and Management of Asthma written by Mani S. Kavuru and published by Professional Communications. This book was released on 2008 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Review of all aspects of asthma from definition and classification through diagnosis and treatment. The role of bronchodilators, anti-inflammatory agents, anti-leukotrienes, and anti-IGE therapy in treatment is discussed, along with complete drug-dosing information. Detailed treatment algorithms based on NIH guidelines are presented. A separate chapter on combination therapy and its importance is included.

Personalizing Asthma Management for the Clinician

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 032349708X
Total Pages : 250 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Personalizing Asthma Management for the Clinician by : Stanley J. Szefler

Download or read book Personalizing Asthma Management for the Clinician written by Stanley J. Szefler and published by Elsevier Health Sciences. This book was released on 2017-09-22 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized medicine is a rapidly emerging area in health care, and asthma management lends itself particularly well to this new development. This practical resource by Dr. Stanley J. Szefler helps you navigate the many asthma medication options available to your patients, as well as providing insights into those which may be introduced within the next several years. Features a wealth of information on available asthma medications, including new immunomodulators, new responses to treatment, and new treatment strategies at all levels of asthma care. Prepares you to meet your patients’ needs regarding asthma exacerbation prevention and asthma prevention. Consolidates today’s available information and guidance in this timely area into one convenient resource.

Pediatric Allergy: Principles and Practice E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 1437737781
Total Pages : 705 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Pediatric Allergy: Principles and Practice E-Book by : Donald Y. M. Leung

Download or read book Pediatric Allergy: Principles and Practice E-Book written by Donald Y. M. Leung and published by Elsevier Health Sciences. This book was released on 2010-10-13 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric Allergy supplies the comprehensive guidance you need to diagnose, manage, and treat virtually any type of allergy seen in children. Drs. Leung, Sampson, Geha, and Szefler present the new full-color second edition, with coverage of the diagnosis and management of anaphylaxis, the immune mechanisms underlying allergic disease, the latest diagnostic tests, and more. Treat the full range of pediatric allergic and immunologic diseases through clinically focused coverage relevant to both allergists and pediatricians. Understand the care and treatment of pediatric patients thanks to clinical pearls discussing the best approaches. Easily refer to appendices that list common food allergies and autoantibodies in autoimmune diseases. Apply the newest diagnostic tests available—for asthma, upper respiratory allergy, and more—and know their benefits and contraindications. Treat the allergy at its source rather than the resulting reactions through an understanding of the immune mechanisms underlying allergic diseases. Get coverage of new research that affects methods of patient treatment and discusses potential reasons for increased allergies in some individuals. Better manage potential anaphylaxis cases through analysis of contributing facts and progression of allergic disease. Effectively control asthma and monitor its progression using the new step-by-step approach. Eliminate difficulty in prescribing antibiotics thanks to coverage of drug allergies and cross-reactivity.

Advances in Asthma

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Author :
Publisher : Springer
ISBN 13 : 9811327904
Total Pages : 189 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Advances in Asthma by : Akihito Yokoyama

Download or read book Advances in Asthma written by Akihito Yokoyama and published by Springer. This book was released on 2018-12-18 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides discussions on bronchial asthma from a clinical perspective, focusing on the recent studies on its pathophysiology, diagnosis and treatment. It also explores the lastest findings regarding the phenotypes and endotypes of asthmatic patients, making it of particular interest to those involved with non-eosinophilic asthma and eosinophilic asthma. Further, it discusses the importance of ILC 2 in eosinophilic asthma, and the accumulated results from the forced oscilliation technique and periostin that are actively practiced in Japan. As some aspects of diagnosis and treatment are different in Western and Asian countries, it is important that the data is disseminated around the globe. The clinical questions addressed by the authors are critical and thought provoking, while the questions raised by the editors are instructive, informative and provide new perspectives on unresolved issues. This book appeals to wide readership from beginning learners to physicians in clinical practice and scholars engaging in basic research.

Immunotherapy in Asthma

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Author :
Publisher : CRC Press
ISBN 13 : 9780824701765
Total Pages : 720 pages
Book Rating : 4.7/5 (17 download)

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Book Synopsis Immunotherapy in Asthma by : Jean Bousquet

Download or read book Immunotherapy in Asthma written by Jean Bousquet and published by CRC Press. This book was released on 1999-08-24 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: This massive reference thoroughly analyzes the mechanisms implicated in the pathophysiology of asthma, such as T helper lymphocyte subsets, and the consequences of various extrinsic and intrinsic factors, and IgE receptor expression-reviewing current concepts in immunotherapeutic approaches for the treatment of this and other allergic diseases. Investigates the only category of treatment showing the potential to affect the natural course of allergic diseases and prevent the onset of asthma. Written by more than 80 internationally renowned pulmonary experts, allergic disease specialists, and basic researchers, Immunotherapy in Asthma discusses the efficacy of new medications examines the role of metachromatic cells, lymphocytes, macrophages, and other cell types present in bronchial biopsies presents basic topics such as the functional and phenotypic properties of Th1 and Th2 cells and their role in allergic disease and the regulation of IgE-mediated inflammatory responses addresses the deleterious effects of smoking and passive exposure to cigarette smoke in children and adults assesses differences and similarities between intrinsic and antigen-induced asthma describes the effects of immunogenic peptides on the cytokine production profile of allergen-specific CD4+ T cells explains the different clinical aspects of allergic responses, such as bronchial hyperreactivity and eosinophilic inflammation of the airways reviews the genetic basis of allergy, as well as risk factors for asthma explores oral, sublingual, local nasal, and local bronchial routes for noninjective immunotherapies evaluates various agents with modulatory effects on normal and pathogenic immune responses focuses on strategies for the prevention of childhood asthma and more! Containing over 3000 references, drawings, and tables, Immunotherapy in Asthma is an indispensable resource for pulmonologists, immunologists, allergists, and medical school students in these disciplines.

Asthma: Targeted Biological Therapies

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Author :
Publisher : Springer
ISBN 13 : 9783319834177
Total Pages : 0 pages
Book Rating : 4.8/5 (341 download)

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Book Synopsis Asthma: Targeted Biological Therapies by : Girolamo Pelaia

Download or read book Asthma: Targeted Biological Therapies written by Girolamo Pelaia and published by Springer. This book was released on 2018-06-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the fundamentals of the use of biologics in asthma, describing the rationale, principles, mechanisms of action, and indications. It offers an excellent balance between basic science and the analysis of clinical trials, updating readers with new developments that are changing the global scenario for targeted biological anti-asthma therapies, especially with regard to more severe disease. A range of therapies are considered, from the humanized monoclonal anti-IgE antibody omalizumab, widely approved as add-on treatment for inadequately controlled disease, through to emerging biologics for which evidence supportive of efficacy is accumulating, including anti-IL-5, anti-IL-4, and anti-IL-13 therapies. One aspect to emerge is the variability in individual response, which suggests a need for characterization of different asthma subtypes to permit the effective implementation of phenotype-targeted treatments. This book will be of interest for pulmonologists, clinical immunologists, and physicians seeking sound information on these therapies, but also for scientists and pharmacologists wishing to enhance their knowledge of the therapeutic implications of the cellular and molecular mechanisms that underlie severe, uncontrolled asthma.

Finding a Path to Safety in Food Allergy

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Author :
Publisher : National Academies Press
ISBN 13 : 0309450314
Total Pages : 575 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Finding a Path to Safety in Food Allergy by : National Academies of Sciences, Engineering, and Medicine

Download or read book Finding a Path to Safety in Food Allergy written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-05-27 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 20 years, public concerns have grown in response to the apparent rising prevalence of food allergy and related atopic conditions, such as eczema. Although evidence on the true prevalence of food allergy is complicated by insufficient or inconsistent data and studies with variable methodologies, many health care experts who care for patients agree that a real increase in food allergy has occurred and that it is unlikely to be due simply to an increase in awareness and better tools for diagnosis. Many stakeholders are concerned about these increases, including the general public, policy makers, regulatory agencies, the food industry, scientists, clinicians, and especially families of children and young people suffering from food allergy. At the present time, however, despite a mounting body of data on the prevalence, health consequences, and associated costs of food allergy, this chronic disease has not garnered the level of societal attention that it warrants. Moreover, for patients and families at risk, recommendations and guidelines have not been clear about preventing exposure or the onset of reactions or for managing this disease. Finding a Path to Safety in Food Allergy examines critical issues related to food allergy, including the prevalence and severity of food allergy and its impact on affected individuals, families, and communities; and current understanding of food allergy as a disease, and in diagnostics, treatments, prevention, and public policy. This report seeks to: clarify the nature of the disease, its causes, and its current management; highlight gaps in knowledge; encourage the implementation of management tools at many levels and among many stakeholders; and delineate a roadmap to safety for those who have, or are at risk of developing, food allergy, as well as for others in society who are responsible for public health.