Annual Reports In Combinatorial Chemistry And Molecular Diversity

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Annual Reports in Combinatorial Chemistry and Molecular Diversity

Author : W.H. Moos
Publisher : Springer Science & Business Media
ISBN 13 : 0306469049
Total Pages : 376 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Annual Reports in Combinatorial Chemistry and Molecular Diversity by : W.H. Moos

Download or read book Annual Reports in Combinatorial Chemistry and Molecular Diversity written by W.H. Moos and published by Springer Science & Business Media. This book was released on 1997-04-30 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combinatorial chemistry and molecular diversity approaches to scientific inquiry and novel product R&D have exploded in the 1990s! For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed, more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research. This first volume covers: (i) combinatorial chemistry, (ii) combinatorial biology and evolution, and (iii) informatics and related topics. Within each section chapters are prepared by experts in the field, including, for example, in Section I: Coverage of mixture pools vs. parallel individual compound synthesis, solution vs. solid-phase synthesis, analytical tools, and automation. Section II highlights selection strategies and library-based evolution, phage display, peptide and nucleic acid libraries. Section III covers databases and library design, high through-put screening, coding strategies vs. deconvolutions, intellectual property issues, deals and collaborations, and successes to date.

Annual Reports in Combinatorial Chemistry and Molecular Diversity

Author : M.R. Pavia
Publisher : Springer
ISBN 13 : 9780792357223
Total Pages : 188 pages
Book Rating : 4.3/5 (572 download)

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Book Synopsis Annual Reports in Combinatorial Chemistry and Molecular Diversity by : M.R. Pavia

Download or read book Annual Reports in Combinatorial Chemistry and Molecular Diversity written by M.R. Pavia and published by Springer. This book was released on 1999-06-30 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combinatorial chemistry and molecular diversity approaches to scientific and novel product R & D have exploded in the 1990s. For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research. The second volume in this series includes contributions on methods, solid phases, purification, analysis, carbohydrates, patent strategies and tactics, diversity profiling and combinatorial series design, and finishes with a survey of chemical libraries yielding biologically active agents and a compendium of solid phase chemistry publications. Each contribution is prepared by a recognized expert resulting in a high quality account of the recent advances in the field.

Annual Reports in Combinatorial Chemistry and Molecular Diversity

Author : W.H. Moos
Publisher : Springer Science & Business Media
ISBN 13 : 9789072199232
Total Pages : 376 pages
Book Rating : 4.1/5 (992 download)

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Book Synopsis Annual Reports in Combinatorial Chemistry and Molecular Diversity by : W.H. Moos

Molecular Diversity and Combinatorial Chemistry

Author : Irwin M. Chaiken
Publisher :
ISBN 13 :
Total Pages : 346 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Diversity and Combinatorial Chemistry by : Irwin M. Chaiken

Download or read book Molecular Diversity and Combinatorial Chemistry written by Irwin M. Chaiken and published by . This book was released on 1996 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reports progress on chemical, enzymatic, phage, and cell-derived libra ries. Discusses synergy between structure-based design and combinatori al libraries. Presents applications of combinatorial libraries to drug discovery and new synthetic catalysis. Reports library screening appr oaches, including the use of NMR. Presents recent advances in solid-ph ase organic synthesis, liquid-phase organic synthesis, and high-throug hput combinatorial organic synthesis. Discusses automation of organic synthesis as well as new methodologies for monitoring solid-phase orga nic synthesis.

Molecular Diversity and Combinatorial Chemistry

Author : Michael C. Pirrung
Publisher : Elsevier
ISBN 13 : 9780080445328
Total Pages : 196 pages
Book Rating : 4.4/5 (453 download)

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Book Synopsis Molecular Diversity and Combinatorial Chemistry by : Michael C. Pirrung

Download or read book Molecular Diversity and Combinatorial Chemistry written by Michael C. Pirrung and published by Elsevier. This book was released on 2004-10-17 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written for advanced undergraduate and graduate students, this textbook makes the main concepts of combinatorial chemistry accessible to the non-specialist.

Combinatorial Chemistry and Technologies

Author : Stanislav Miertus
Publisher : CRC Press
ISBN 13 : 0824758374
Total Pages : 616 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Combinatorial Chemistry and Technologies by : Stanislav Miertus

Download or read book Combinatorial Chemistry and Technologies written by Stanislav Miertus and published by CRC Press. This book was released on 2005-04-12 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several books on the market cover combinatorial techniques, but they offer just a limited perspective of the field, focusing on selected aspects without examining all approaches and integrated technologies. Combinatorial Chemistry and Technologies: Methods and Applications answers the demand for a complete overview of the field, covering all of the methodologies used in the design, synthesis, and screening of molecular libraries. Now in its second edition, this volume updates prior content and explores new areas such as catalysis, applications in biotechnology, and current ICS-UNIDO activities. Topics include the generation of molecular diversity by chemical methods using solution- and solid-phase chemistries, biological approaches for the production and screening of peptides, antibody and oligonucleotide libraries, and the application of computer-assisted approaches to guide library synthesis. The book establishes the link between combinatorial chemistry and molecular modeling and illustrates the importance of economics and patenting in combinatorial technologies. Valuable to technologists and researchers as an introductory survey on the many aspects of combinatorial chemistry and combinatorial technology, Combinatorial Chemistry and Technologies: Methods and Applications offers an overview of a field that promises broad applicability in the identification of new drugs, as well as in diagnostics, new materials, and catalysis.

Annual Reports in Combinatorial Chemistry and Molecular Diversity

Author :
Publisher :
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Annual Reports in Combinatorial Chemistry and Molecular Diversity by :

Download or read book Annual Reports in Combinatorial Chemistry and Molecular Diversity written by and published by . This book was released on 1997 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Analytical Techniques in Combinatorial Chemistry

Author : Michael E. Swartz
Publisher : CRC Press
ISBN 13 : 0824746694
Total Pages : 314 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Analytical Techniques in Combinatorial Chemistry by : Michael E. Swartz

Download or read book Analytical Techniques in Combinatorial Chemistry written by Michael E. Swartz and published by CRC Press. This book was released on 2000-02-18 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume aims to provide the necessary tools for developing methods and analyzing results in the drug discovery process, and supports documenting and managing the process in a combinatorial setting. It describes the chromatographic and spectroscopic techniques used to generate chemical and molecular diversity in new compounds, focusing on applications of information management systems, instrumentation, and robotics.

Combinatorial Chemistry and Technology

Author : Stanislav Miertus
Publisher : CRC Press
ISBN 13 : 9781420000566
Total Pages : 456 pages
Book Rating : 4.0/5 (5 download)

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Book Synopsis Combinatorial Chemistry and Technology by : Stanislav Miertus

Download or read book Combinatorial Chemistry and Technology written by Stanislav Miertus and published by CRC Press. This book was released on 1999-07-01 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Provides comprehensive coverage of the current combinatorial methodologies and technologies employed for the design, synthesis, and screening of molecular ""libraries."" Features assessments of computer-assisted approaches to guiding library synthesis. Designed to satisfy the demand to create, produce in high yield and purity, and rapidly screen huge numbers of molecules."

Progress in Medicinal Chemistry

Author :
Publisher : Elsevier
ISBN 13 : 9780080862842
Total Pages : 308 pages
Book Rating : 4.8/5 (628 download)

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Book Synopsis Progress in Medicinal Chemistry by :

Download or read book Progress in Medicinal Chemistry written by and published by Elsevier. This book was released on 1999-05-14 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Medicinal Chemistry

Combinatorial Chemistry

Author : Günther Jung
Publisher : John Wiley & Sons
ISBN 13 : 352761351X
Total Pages : 634 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Combinatorial Chemistry by : Günther Jung

Download or read book Combinatorial Chemistry written by Günther Jung and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: The story of success goes on and on - with a new book on combinatorial chemistry, edited by Gunther Jung! Combinatorial chemistry is a proven time- and resource-saving synthetic method of outstanding importance for industrial processes. Compound libraries help to save time and money, especially in the search for new drugs, and therefore play a pivotal role in solving the problem of the worldwide increasing demand for new and more active drugs. Not only substances, which are of interest for pharmaceutical chemistry, but also materials, catalysts, and biomolecules such as DNA or oligosaccharides are readily available with high structural diversities. The broad scope of combinatorial sciences is reflected by this book, edited by Gunther Jung: The synthetic methods discussed range from solid-phase to solution-phase synthesis, from preparations of small molecules such as amines or alcohols to those of complex biomolecules. Feasible methods, efficient techniques, new trends in automation, and state-of-the-art fast instrumental analytical and screening methods are presented with many practical tips and tricks for everybody working in combinatorial chemistry. This is the book written by specialists for specialists and for everyone aspiring to become an insider! It is an indispensible source of information for researchers working in organic synthesis, catalysis, biochemistry, and biotechnology, pharmaceutical and clinical chemistry, material sciences, and analytical chemistry.

Combinatorial Chemistry

Author : Willi Bannwarth
Publisher : John Wiley & Sons
ISBN 13 : 3527607382
Total Pages : 694 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Combinatorial Chemistry by : Willi Bannwarth

Download or read book Combinatorial Chemistry written by Willi Bannwarth and published by John Wiley & Sons. This book was released on 2006-05-12 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this practice-oriented handbook features thoroughly updated contents, including recent developments in parallel synthesis. A new chapter on screening complements the overview of combinatorial strategy and synthetic methods. "Experimental details and complete reaction data [...] are a constant theme running through this work" (Angewandte Chemie) "Recommended to newcomers in the field of combinatorial chemical synthesis because of its broad scope" (Journal of the American Chemical Society)

Analytical Methods in Combinatorial Chemistry

Author : Bing Yan
Publisher : CRC Press
ISBN 13 : 1420003526
Total Pages : 238 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Analytical Methods in Combinatorial Chemistry by : Bing Yan

Download or read book Analytical Methods in Combinatorial Chemistry written by Bing Yan and published by CRC Press. This book was released on 2010-08-09 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the benchmark first edition of this book, chemical library and combinatorial chemistry methods have developed into mature technologies. There have also been significant shifts in emphasis in combinatorial synthesis. Reflecting the growth in the field and the heightened focus on select areas, Analytical Methods in Combinator

Drug Discovery from Nature

Author : S. Grabley
Publisher : Springer Science & Business Media
ISBN 13 : 9783540648444
Total Pages : 380 pages
Book Rating : 4.6/5 (484 download)

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Book Synopsis Drug Discovery from Nature by : S. Grabley

Download or read book Drug Discovery from Nature written by S. Grabley and published by Springer Science & Business Media. This book was released on 1998-11-26 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is unique in covering the present status and future potential of natural products in drug discovery. It provides readers with recent information regarding the impact on drug discovery, development and strategies, technical and automation aspects, and methods based on biochemistry as well as molecular biology, highlighting compounds from natural sources. Special emphasis is placed on the various strategies to gain access to natural compounds and combinatorial approaches by making use of both synthetic and biological methods.

Annual Reports on NMR Spectroscopy

Author : Graham A. Webb
Publisher : Elsevier
ISBN 13 : 0080461980
Total Pages : 320 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Annual Reports on NMR Spectroscopy by : Graham A. Webb

Download or read book Annual Reports on NMR Spectroscopy written by Graham A. Webb and published by Elsevier. This book was released on 2006-05-10 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has grown to such importance as NMR spectroscopy. It is used in all branches of science where precise structural determination is required and where the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a premier means for the specialist and nonspecialist alike to become familiar with new techniques and applications of NMR spectroscopy. * Includes comprehensive review articles on NMR Spectroscopy * NMR is used in all branches of science * No other technique has grown to such importance as NMR Spectroscopy in recent years

Integrated Drug Discovery Technologies

Author : Houng-Yau Mei
Publisher : CRC Press
ISBN 13 : 082474473X
Total Pages : 603 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Integrated Drug Discovery Technologies by : Houng-Yau Mei

Download or read book Integrated Drug Discovery Technologies written by Houng-Yau Mei and published by CRC Press. This book was released on 2002-03-19 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrated Drug Discovery Technologies provides a global overview of emerging drug development technologies by presenting and integrating new techniques from the disciplines of chemistry, biology, and computational sciences. It combines integration of contemporary mechanization with strategies in drug delivery. Topics include: functional genomics, microfabrication techniqes, integrated proteomics technologies, high throughput screening, and fluorescence correlation spectroscopy methods.

Amino Acids, Peptides and Proteins in Organic Chemistry, Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis

Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527641572
Total Pages : 541 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Amino Acids, Peptides and Proteins in Organic Chemistry, Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis by :

Download or read book Amino Acids, Peptides and Proteins in Organic Chemistry, Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis written by and published by John Wiley & Sons. This book was released on 2011-06-03 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the fourth of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures. The 5 volumes cover the following topics: Volume 1: Origins and Synthesis of Amino Acids Volume 2: Modified Amino Acids, Organocatalysis and Enzymes Volume 3: Building Blocks, Catalysis and Coupling Chemistry Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Volume 5: Analysis and Function of Amino Acids and Peptides The fourth volume in this series is structured in three main sections. The first section is about protection reactions and amino acid based peptidomimetics. The second, and most extensive, part is devoted to the medicinal chemistry of amino acids. It includes, among others, the chemistry of alpha- and beta amino acids, peptide drugs, and advances in N- and O-glycopeptide synthesis. The final part deals with amino acids in combinatorial synthesis. Methods, such as phage display, library peptide synthesis, and computational design are described. Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage. Further information about the 5 Volume Set and purchasing details can be viewed here.