Animal Feeding Stuffs Methods Of Sampling And Analysis Determination Of Mineral Oil Saturated Hydrocarbons Mosh And Mineral Oil Aromatic Hydrocarbons Moah With On Line Hplc Gc Fid Analysis

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ISBN 13 : 9789276532781
Total Pages : 0 pages
Book Rating : 4.5/5 (327 download)

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Download or read book Mineral Oil in Infant Formulas written by and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mineral oil saturated hydrocarbons (MOSH) and mineral oil aromatic hydrocarbons (MOAH) consist of a mixture of various hydrocarbons that are difficult to resolve in a chromatographic column. They produce complex unresolved chromatographic signals (called humps). The quantification of total MOSH and total MOAH mass fractions requires proper integration of the respective humps, after background subtraction and the removal of the remaining interfering peaks. Such an operation is prone to subjective judgement that may increase the scatter of reported results. The European Union Reference Laboratory for Food Contact Materials (EURL-FCM) organised the first virtual interlaboratory comparison (e-ILC) "JRC-IF-2021-04" to assess the capabilities of the participants in "integrating chromatograms of mineral oils in infant formulas (IF). A set of chromatograms in "cdf" (binary) or "csv" (ascii) formats related to IF samples, hexane baselines, and retention time calibrations were provided to the participants. They were requested to submit results for the mass fraction of total MOSH and total MOAH in seven IF samples. Thirty participants registered to this round and submitted results. Most of the participants (26 out of 30) reported satisfactory peak areas for the two internal standards (CyCy and 2-MN) with a robust relative standard deviation (RSD) of 0.5 %. A significantly larger scatter of results was observed for total MOSH and total MOAH mass fractions, with RSD ranging from 6 to 18 %. This may be attributed to the various integration strategies used by the participants keeping or removing interfering peaks and overriding humps and the different baseline corrections applied. Specific guidance is provided based on the good practices identified and problems encountered by the laboratories monitoring MOSH/MOAH in infant formulas. These guidelines aim to decrease the variability of results due to the integration of chromatograms. Detailed information is provided in this report.