An Introduction To Protein Informatics

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An Introduction to Protein Informatics

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Author : Karl-Heinz Zimmermann
Publisher : Springer Science & Business Media
ISBN 13 : 1441992103
Total Pages : 298 pages
Book Rating : 4.4/5 (419 download)

Book Synopsis An Introduction to Protein Informatics by : Karl-Heinz Zimmermann

Download or read book An Introduction to Protein Informatics written by Karl-Heinz Zimmermann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein informatics is a newer name for an already existing discipline. It encompasses the techniques used in bioinformatics and molecular modeling that are related to proteins. While bioinformatics is mainly concerned with the collection, organization, and analysis of biological data, molecular modeling is devoted to representation and manipulation of the structure of proteins. Protein informatics requires substantial prerequisites on computer science, mathematics, and molecular biology. The approach chosen here, allows a direct and rapid grasp on the subject starting from basic knowledge of algorithm design, calculus, linear algebra, and probability theory. An Introduction to Protein Informatics, a professional monograph will provide the reader a comprehensive introduction to the field of protein informatics. The text emphasizes mathematical and computational methods to tackle the central problems of alignment, phylogenetic reconstruction, and prediction and sampling of protein structure. An Introduction to Protein Informatics is designed for a professional audience, composed of researchers and practitioners within bioinformatics, molecular modeling, algorithm design, optimization, and pattern recognition. This book is also suitable as a graduate-level text for students in computer science, mathematics, and biomedicine.

An Introduction To Protein Informatics

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Author : Zimmermann Karl-Heinz
Publisher :
ISBN 13 : 9788181287595
Total Pages : 300 pages
Book Rating : 4.2/5 (875 download)

Book Synopsis An Introduction To Protein Informatics by : Zimmermann Karl-Heinz

Download or read book An Introduction To Protein Informatics written by Zimmermann Karl-Heinz and published by . This book was released on 2007-10-01 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Proteome Informatics

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Author : Conrad Bessant
Publisher : Royal Society of Chemistry
ISBN 13 : 1782624287
Total Pages : 428 pages
Book Rating : 4.7/5 (826 download)

Book Synopsis Proteome Informatics by : Conrad Bessant

Download or read book Proteome Informatics written by Conrad Bessant and published by Royal Society of Chemistry. This book was released on 2016-11-23 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together world experts to provide clear explanations of the key algorithms, workflows and analysis frameworks, Proteome Informatics will provide a detailed introduction to the main informatics topics that underpin the various LC-MS/MS protocols used for protein identification and quantitation.

Protein Structure Informatics

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Author : Arun Jagota
Publisher : Bioinformatics by the Bay
ISBN 13 : 9780970029713
Total Pages : 69 pages
Book Rating : 4.0/5 (297 download)

Book Synopsis Protein Structure Informatics by : Arun Jagota

Download or read book Protein Structure Informatics written by Arun Jagota and published by Bioinformatics by the Bay. This book was released on 2002 with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteins fold in interesting and intriguing ways. Importantly, the structure of a protein can provide additional clues to its function(s) than does its sequence alone. Scientists interested in characterizing a novel protein sequence should therefore not only familiarize themselves with computer tools and methods for sequence analysis but also with those for structure analysis. Computer scientists interested in developing software tools for bioinformatics will find that structure analysis is no less interesting and challenging than sequence analysis. Both scientists and computer scientists will note that the field of protein structure analysis is going to become increasingly important in coming years, now that the post-genomic era is here. This short book introduces the topic of protein structure informatics in two parts. Part I covers the main public-domain protein structure databases, and associated tools such as structure viewers and search tools. Part II covers problems and algorithms for aligning a structure to a structure, a sequence to a structure, for predicting a structure for a sequence, on "protein structure profiles", and the molecular docking problem. All chapters contain references for further reading. This book has been cooking slowly for more than two years. Over this period, it has undergone numerous revisions and refinements. The material has also been presented and refined in classes taught by the author at the University of California, Santa Cruz extension.

Introduction to Proteins

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Author : Amit Kessel
Publisher : CRC Press
ISBN 13 : 1498747213
Total Pages : 1423 pages
Book Rating : 4.4/5 (987 download)

Book Synopsis Introduction to Proteins by : Amit Kessel

Download or read book Introduction to Proteins written by Amit Kessel and published by CRC Press. This book was released on 2018-03-22 with total page 1423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the structure, function, and motion of proteins for students, faculty, and researchers at all levels. The book covers proteins and enzymes across a wide range of contexts and applications, including medical disorders, drugs, toxins, chemical warfare, and animal behavior. Each chapter includes a Summary, Exercies, and References. New features in the thoroughly-updated second edition include: A brand-new chapter on enzymatic catalysis, describing enzyme biochemistry, classification, kinetics, thermodynamics, mechanisms, and applications in medicine and other industries. These are accompanied by multiple animations of biochemical reactions and mechanisms, accessible via embedded QR codes (which can be viewed by smartphones) An in-depth discussion of G-protein-coupled receptors (GPCRs) A wider-scale description of biochemical and biophysical methods for studying proteins, including fully accessible internet-based resources, such as databases and algorithms Animations of protein dynamics and conformational changes, accessible via embedded QR codes Additional features Extensive discussion of the energetics of protein folding, stability and interactions A comprehensive view of membrane proteins, with emphasis on structure-function relationship Coverage of intrinsically unstructured proteins, providing a complete, realistic view of the proteome and its underlying functions Exploration of industrial applications of protein engineering and rational drug design Each chapter includes a Summary, Exercies, and References Approximately 300 color images Downloadable solutions manual available at www.crcpress.com For more information, including all presentations, tables, animations, and exercises, as well as a complete teaching course on proteins' structure and function, please visit the author's website: http://ibis.tau.ac.il/wiki/nir_bental/index.php/Introduction_to_Proteins_Book. Praise for the first edition "This book captures, in a very accessible way, a growing body of literature on the structure, function and motion of proteins. This is a superb publication that would be very useful to undergraduates, graduate students, postdoctoral researchers, and instructors involved in structural biology or biophysics courses or in research on protein structure-function relationships." --David Sheehan, ChemBioChem, 2011 "Introduction to Proteins is an excellent, state-of-the-art choice for students, faculty, or researchers needing a monograph on protein structure. This is an immensely informative, thoroughly researched, up-to-date text, with broad coverage and remarkable depth. Introduction to Proteins would provide an excellent basis for an upper-level or graduate course on protein structure, and a valuable addition to the libraries of professionals interested in this centrally important field." --Eric Martz, Biochemistry and Molecular Biology Education, 2012

Protein Bioinformatics

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Author : Ingvar Eidhammer
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 384 pages
Book Rating : 4.3/5 (91 download)

Book Synopsis Protein Bioinformatics by : Ingvar Eidhammer

Download or read book Protein Bioinformatics written by Ingvar Eidhammer and published by John Wiley & Sons. This book was released on 2004-02-13 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pairwise global alignment of sequences. Pairwise local alignment and database search. Statical analysis. Multiple global alignment and phylogenetic trees. Scoring matrices. Profiles. Sequence patterns. Structures and structure descriptions. Superposition and Dynamic programming. Geometric techniques. Clustering: Combining local similarities. Significance and assessment of structure comparisons. Multiple structure comparison. Protein structure classification. Structure prediction: Threading. Basics in mathematics, probability and algorithms. Introduction to molecular biology.

Applied Bioinformatics

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Author : Paul M. Selzer
Publisher : Springer
ISBN 13 : 3319683012
Total Pages : 197 pages
Book Rating : 4.3/5 (196 download)

Book Synopsis Applied Bioinformatics by : Paul M. Selzer

Download or read book Applied Bioinformatics written by Paul M. Selzer and published by Springer. This book was released on 2018-05-02 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces readers to the basic principles of bioinformatics and the practical application and utilization of computational tools, without assuming any prior background in programming or informatics. It provides a coherent overview of the complex field and focuses on the implementation of online tools, genome databases and software that can benefit scientists and students in the life sciences. Training tutorials with practical bioinformatics exercises and solutions facilitate the understanding and application of such tools and interpretation of results. In addition, a glossary explains terminology that is widely used in the field. This straightforward introduction to applied bioinformatics offers an essential resource for students, as well as scientists seeking to understand the basis of sequencing analysis, functional genomics and protein structure predictions.

Molecular Databases for Protein Sequences and Structure Studies

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Author : John A.A. Sillince
Publisher : Springer Science & Business Media
ISBN 13 : 3642768091
Total Pages : 254 pages
Book Rating : 4.6/5 (427 download)

Book Synopsis Molecular Databases for Protein Sequences and Structure Studies by : John A.A. Sillince

Download or read book Molecular Databases for Protein Sequences and Structure Studies written by John A.A. Sillince and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: The amount of molecular information is too vast to be acquired without the use of computer-bases systems. The authors introduce students entering research in molecular biology and related fields into the efficient use of the numerous databases available. They show the broad scientific context of these databases and their latest developments. They also put the biological, chemical and computational aspects of structural information on biomolecules into perspective. The book is required reading for researchers and students who plan to use modern computer environment in their research.

Computational Methods for Protein Structure Prediction and Modeling

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Author : Ying Xu
Publisher : Springer Science & Business Media
ISBN 13 : 0387688250
Total Pages : 335 pages
Book Rating : 4.3/5 (876 download)

Book Synopsis Computational Methods for Protein Structure Prediction and Modeling by : Ying Xu

Download or read book Computational Methods for Protein Structure Prediction and Modeling written by Ying Xu and published by Springer Science & Business Media. This book was released on 2010-05-05 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume Two of this two-volume sequence presents a comprehensive overview of protein structure prediction methods and includes protein threading, De novo methods, applications to membrane proteins and protein complexes, structure-based drug design, as well as structure prediction as a systems problem. A series of appendices review the biological and chemical basics related to protein structure, computer science for structural informatics, and prerequisite mathematics and statistics.

Computational Methods for Protein Structure Prediction and Modeling

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Author : Ying Xu
Publisher : Springer
ISBN 13 : 9781441922069
Total Pages : 0 pages
Book Rating : 4.9/5 (22 download)

Book Synopsis Computational Methods for Protein Structure Prediction and Modeling by : Ying Xu

Download or read book Computational Methods for Protein Structure Prediction and Modeling written by Ying Xu and published by Springer. This book was released on 2010-12-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume Two of this two-volume sequence presents a comprehensive overview of protein structure prediction methods and includes protein threading, De novo methods, applications to membrane proteins and protein complexes, structure-based drug design, as well as structure prediction as a systems problem. A series of appendices review the biological and chemical basics related to protein structure, computer science for structural informatics, and prerequisite mathematics and statistics.

Scalable Big Data Analytics for Protein Bioinformatics

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Author : Dariusz Mrozek
Publisher : Springer
ISBN 13 : 3319988395
Total Pages : 331 pages
Book Rating : 4.3/5 (199 download)

Book Synopsis Scalable Big Data Analytics for Protein Bioinformatics by : Dariusz Mrozek

Download or read book Scalable Big Data Analytics for Protein Bioinformatics written by Dariusz Mrozek and published by Springer. This book was released on 2018-09-25 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a focus on proteins and their structures. The text describes various scalable solutions for protein structure similarity searching, carried out at main representation levels and for prediction of 3D structures of proteins. Emphasis is placed on techniques that can be used to accelerate similarity searches and protein structure modeling processes. The content of the book is divided into four parts. The first part provides background information on proteins and their representation levels, including a formal model of a 3D protein structure used in computational processes, and a brief overview of the technologies used in the solutions presented in the book. The second part of the book discusses Cloud services that are utilized in the development of scalable and reliable cloud applications for 3D protein structure similarity searching and protein structure prediction. The third part of the book shows the utilization of scalable Big Data computational frameworks, like Hadoop and Spark, in massive 3D protein structure alignments and identification of intrinsically disordered regions in protein structures. The fourth part of the book focuses on finding 3D protein structure similarities, accelerated with the use of GPUs and the use of multithreading and relational databases for efficient approximate searching on protein secondary structures. The book introduces advanced techniques and computational architectures that benefit from recent achievements in the field of computing and parallelism. Recent developments in computer science have allowed algorithms previously considered too time-consuming to now be efficiently used for applications in bioinformatics and the life sciences. Given its depth of coverage, the book will be of interest to researchers and software developers working in the fields of structural bioinformatics and biomedical databases.

Introduction to Protein Structure Prediction

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Author : Huzefa Rangwala
Publisher : Wiley
ISBN 13 : 9780470470596
Total Pages : 516 pages
Book Rating : 4.4/5 (75 download)

Book Synopsis Introduction to Protein Structure Prediction by : Huzefa Rangwala

Download or read book Introduction to Protein Structure Prediction written by Huzefa Rangwala and published by Wiley. This book was released on 2010-12-28 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: A look at the methods and algorithms used to predict protein structure A thorough knowledge of the function and structure of proteins is critical for the advancement of biology and the life sciences as well as the development of better drugs, higher-yield crops, and even synthetic bio-fuels. To that end, this reference sheds light on the methods used for protein structure prediction and reveals the key applications of modeled structures. This indispensable book covers the applications of modeled protein structures and unravels the relationship between pure sequence information and three-dimensional structure, which continues to be one of the greatest challenges in molecular biology. With this resource, readers will find an all-encompassing examination of the problems, methods, tools, servers, databases, and applications of protein structure prediction and they will acquire unique insight into the future applications of the modeled protein structures. The book begins with a thorough introduction to the protein structure prediction problem and is divided into four themes: a background on structure prediction, the prediction of structural elements, tertiary structure prediction, and functional insights. Within those four sections, the following topics are covered: Databases and resources that are commonly used for protein structure prediction The structure prediction flagship assessment (CASP) and the protein structure initiative (PSI) Definitions of recurring substructures and the computational approaches used for solving sequence problems Difficulties with contact map prediction and how sophisticated machine learning methods can solve those problems Structure prediction methods that rely on homology modeling, threading, and fragment assembly Hybrid methods that achieve high-resolution protein structures Parts of the protein structure that may be conserved and used to interact with other biomolecules How the loop prediction problem can be used for refinement of the modeled structures The computational model that detects the differences between protein structure and its modeled mutant Whether working in the field of bioinformatics or molecular biology research or taking courses in protein modeling, readers will find the content in this book invaluable.

Protein Structure Prediction

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Author : Igor F. Tsigelny
Publisher : Internat'l University Line
ISBN 13 : 9780963681775
Total Pages : 540 pages
Book Rating : 4.6/5 (817 download)

Book Synopsis Protein Structure Prediction by : Igor F. Tsigelny

Download or read book Protein Structure Prediction written by Igor F. Tsigelny and published by Internat'l University Line. This book was released on 2002 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Informatics In Proteomics

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Author : Sudhir Srivastava
Publisher : CRC Press
ISBN 13 : 142002762X
Total Pages : 474 pages
Book Rating : 4.4/5 (2 download)

Book Synopsis Informatics In Proteomics by : Sudhir Srivastava

Download or read book Informatics In Proteomics written by Sudhir Srivastava and published by CRC Press. This book was released on 2005-06-24 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: The handling and analysis of data generated by proteomics investigations represent a challenge for computer scientists, biostatisticians, and biologists to develop tools for storing, retrieving, visualizing, and analyzing genomic data. Informatics in Proteomics examines the ongoing advances in the application of bioinformatics to proteomics researc

Introduction to Protein Science

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Author : Arthur M. Lesk
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 338 pages
Book Rating : 4.3/5 (91 download)

Book Synopsis Introduction to Protein Science by : Arthur M. Lesk

Download or read book Introduction to Protein Science written by Arthur M. Lesk and published by Oxford University Press, USA. This book was released on 2004 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Useful for students on biosciences degrees, this book provides an introduction to the study of proteins. It contains the aspects related to genomics and proteomics that have paved the way for an explosion of interest in protein structure and function.

Computational Biology and Genome Informatics

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Author : Jason T. L. Wang
Publisher : World Scientific
ISBN 13 : 9812382577
Total Pages : 266 pages
Book Rating : 4.8/5 (123 download)

Book Synopsis Computational Biology and Genome Informatics by : Jason T. L. Wang

Download or read book Computational Biology and Genome Informatics written by Jason T. L. Wang and published by World Scientific. This book was released on 2003 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains articles written by experts on a wide range of topics that are associated with the analysis and management of biological information at the molecular level. It contains chapters on RNA and protein structure analysis, DNA computing, sequence mapping, genome comparison, gene expression data mining, metabolic network modeling, and phyloinformatics. The important work of some representative researchers in bioinformatics is brought together for the first time in one volume. The topic is treated in depth and is related to, where applicable, other emerging technologies such as data mining and visualization. The goal of the book is to introduce readers to the principle techniques of bioinformatics in the hope that they will build on them to make new discoveries of their own. Contents: Exploring RNA Intermediate Conformations with the Massively Parallel Genetic Algorithm; Introduction to Self-Assembling DNA Nanostructures for Computation and Nanofabrication; Mapping Sequence to Rice FPC; Graph Theoretic Sequence Clustering Algorithms and their Applications to Genome Comparison; The Protein Information Resource for Functional Genomics and Proteomics; High-Grade Ore for Data Mining in 3D Structures; Protein Classification: A Geometric Hashing Approach; Interrelated Clustering: An Approach for Gene Expression Data Analysis; Creating Metabolic Network Models Using Text Mining and Expert Knowledge; Phyloinformatics and Tree Networks. Readership: Molecular biologists who rely on computers and mathematical scientists with interests in biology.

Molecular Biology of the Cell

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Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

Book Synopsis Molecular Biology of the Cell by :

Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: