The Neurobiology of Aging and Alzheimer Disease in Down Syndrome

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Author :
Publisher : Academic Press
ISBN 13 : 0128188464
Total Pages : 354 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Neurobiology of Aging and Alzheimer Disease in Down Syndrome by : Elizabeth Head

Download or read book The Neurobiology of Aging and Alzheimer Disease in Down Syndrome written by Elizabeth Head and published by Academic Press. This book was released on 2021-08-31 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of Aging and Alzheimer Disease in Down Syndrome provides a multidisciplinary approach to the understanding of aging and Alzheimer disease in Down syndrome that is synergistic and focused on efforts to understand the neurobiology as it pertains to interventions that will slow or prevent disease. The book provides detailed knowledge of key molecular aspects of aging and neurodegeneration in Down Syndrome by bringing together different models of the diseases and highlighting multiple techniques. Additionally, it includes case studies and coverage of neuroimaging, neuropathological and biomarker changes associated with these cohorts. This is a must-have resource for researchers who work with or study aging and Alzheimer disease either in the general population or in people with Down syndrome, for academic and general physicians who interact with sporadic dementia patients and need more information about Down syndrome, and for new investigators to the aging and Alzheimer/Down syndrome arena. Discusses the complexities involved with aging and Alzheimer’s disease in Down syndrome Summarizes the neurobiology of aging that requires management in adults with DS and leads to healthier aging and better quality of life into old age Serves as learning tool to orient researchers to the key challenges and offers insights to help establish critical areas of need for further research

Alzheimer Disease, Down Syndrome, and Their Relationship

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Author :
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Alzheimer Disease, Down Syndrome, and Their Relationship by : Joseph Maurice Berg

Download or read book Alzheimer Disease, Down Syndrome, and Their Relationship written by Joseph Maurice Berg and published by Oxford University Press, USA. This book was released on 1993 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unique, up-to-date and comprehensive, this book considers in depth the remarkable association between Down Syndrome and Alzheimer disease. It provides overviews of each condition, followed by detailed accounts and analyses of hypotheses that attempt to account for the presence of Down Syndrome as a risk factor for Alzheimer disease. The data and discussions presented, including practical diagnostic and management recommendations, will be vital for health professionals involved in caring for adults with Down Syndrome, and for researchers exploring biological and behavioral aspects of the intriguing link between the two disorders.

The Relationship Between Alzheimer's Disease and Down Syndrome

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Author :
Publisher :
ISBN 13 :
Total Pages : 148 pages
Book Rating : 4.:/5 (728 download)

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Book Synopsis The Relationship Between Alzheimer's Disease and Down Syndrome by : Bronach Maura Crawley

Download or read book The Relationship Between Alzheimer's Disease and Down Syndrome written by Bronach Maura Crawley and published by . This book was released on 1984 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Down Syndrome and Alzheimer's Disease

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Author :
Publisher : Radcliffe Publishing
ISBN 13 : 9781857756371
Total Pages : 206 pages
Book Rating : 4.7/5 (563 download)

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Book Synopsis Down Syndrome and Alzheimer's Disease by : Vee P. Prasher

Download or read book Down Syndrome and Alzheimer's Disease written by Vee P. Prasher and published by Radcliffe Publishing. This book was released on 2006 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addresses the underlying biological abnormalities of Dementia in Alzheimer's Disease (DAD) in people with Down syndrome. Brings together recent research findings relating to the neuropathology, genetics, blood markers and neurophysiology of Alzheimer's disease in older adults with Down syndrome.

Down Syndrome and Alzheimer's Disease

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Author :
Publisher : CRC Press
ISBN 13 : 149879288X
Total Pages : 199 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Down Syndrome and Alzheimer's Disease by : Vee Prasher

Download or read book Down Syndrome and Alzheimer's Disease written by Vee Prasher and published by CRC Press. This book was released on 2018-12-14 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book in the field to address the underlying biological abnormalities of Dementia in Alzheimer’s Disease (DAD) in people with Down syndrome. It brings together research findings relating to the neuropathology, genetics, blood markers and neurophysiology of Alzheimer’s disease in older adults with Down syndrome. Down Syndrome and Alzheimer’s Disease presents vital information to medical professionals who provide clinical care to people with Alzheimer’s disease and Down syndrome. It will also be of great benefit to researchers with an interest in Alzheimer’s disease and Down syndrome and academics researching ageing issues in people with Down Syndrome. It complements Alzheimer's Disease and Dementia in Down Syndrome and Intellectual Disabilities by the same author.

Viruses: Essential Agents of Life

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 940074899X
Total Pages : 432 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Viruses: Essential Agents of Life by : Günther Witzany

Download or read book Viruses: Essential Agents of Life written by Günther Witzany and published by Springer Science & Business Media. This book was released on 2012-11-13 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: A renaissance of virus research is taking centre stage in biology. Empirical data from the last decade indicate the important roles of viruses, both in the evolution of all life and as symbionts of host organisms. There is increasing evidence that all cellular life is colonized by exogenous and/or endogenous viruses in a non-lytic but persistent lifestyle. Viruses and viral parts form the most numerous genetic matter on this planet.

Intellectual Disabilities in Down Syndrome from Birth and throughout Life: Assessment and Treatment

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889450457
Total Pages : 183 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Intellectual Disabilities in Down Syndrome from Birth and throughout Life: Assessment and Treatment by : Marie-Claude Potier

Download or read book Intellectual Disabilities in Down Syndrome from Birth and throughout Life: Assessment and Treatment written by Marie-Claude Potier and published by Frontiers Media SA. This book was released on 2017-02-24 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on the multiple aspects of cognitive impairment in Down syndrome (DS), from genes to behavior to treatment, has made tremendous progress in the last decade. The study of congenital intellectual disabilities such as DS is challenging since they originate from the earliest stages of development and both the acquisition of cognitive skills and neurodegenerative pathologies are cumulative. Comorbidities such as cardiac malformations, sleep apnea, diabetes and dementia are frequent in the DS population, as well, and their increased risk provides a means of assessing early stages of these pathologies that is relevant to the general population. Notably, persons with DS will develop the histopathology of Alzheimer’s disease (formation of neuritic plaques and tangles) and are at high risk for dementia, something that cannot be predicted in the population at large. Identification of the gene encoding the amyloid precursor protein, its localization to chromosome 21 in the 90’s and realization that all persons with DS develop pathology identified this as an important piece of the amyloid cascade hypothesis in Alzheimer’s disease. Awareness of the potential role of people with DS in understanding progression and treatment as well as identification of genetic risk factors and also protective factors for AD is reawakening. For the first time since DS was recognized, major pharmaceutical companies have entered the search for ameliorative treatments, and phase II clinical trials to improve learning and memory are in progress. Enriched environment, brain stimulation and alternative therapies are being tested while clinical assessment is improving, thus increasing the chances of success for therapeutic interventions. Researchers and clinicians are actively pursuing the possibility of prenatal treatments for many conditions, an area with a huge potential impact for developmental disorders such as DS. Our goal here is to present an overview of recent advances with an emphasis on behavioral and cognitive deficits and how these issues change through life in DS. The relevance of comorbidities to the end phenotypes described and relevance of pharmacological targets and possible treatments will be considerations throughout.

Down Syndrome and Alzheimer Disease

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Author :
Publisher : Wiley-Liss
ISBN 13 : 9780471588412
Total Pages : 334 pages
Book Rating : 4.5/5 (884 download)

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Book Synopsis Down Syndrome and Alzheimer Disease by : Lynn Nadel

Download or read book Down Syndrome and Alzheimer Disease written by Lynn Nadel and published by Wiley-Liss. This book was released on 1992-09-28 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Findings and reviews by foremost experts offer a comprehensive survey regarding the present state of our understanding of the development of Alzheimer disease in people with Down Syndrome and the relationship between these disorders. Coverage includes many processes involved in the pathogenesis of Alzheimer disease, the latest molecular and cellular techniques for defining these processes, the usefulness of animal model systems for studying normal and abnormal development and function of the central nervous system, the relationship between chromosome 21 and Alzheimer disease and much more.

CAMDEX-DS

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Author :
Publisher : Cambridge University Press
ISBN 13 : 9780521547949
Total Pages : 130 pages
Book Rating : 4.5/5 (479 download)

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Book Synopsis CAMDEX-DS by : Sarah Ball

Download or read book CAMDEX-DS written by Sarah Ball and published by Cambridge University Press. This book was released on 2006-07-06 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: CAMDEX-DS is a comprehensive assessment tool for diagnosing dementia in people with Down's syndrome (a group known to be at particular risk of dementia). Based upon CAMDEX-R, CAMDEX-DS has been modified for use with intellectual disability. In order to differentiate decline due to dementia or other mental disorders from pre-existing impairment, particular emphasis has been placed on establishing change from the individual's best level of functioning. The pack is comprised of a structured informant interview, a direct assessment of the patient/participant (CAMCOG), and guidance for diagnosis and post-diagnosis intervention, providing a reliable way to identify dementia (and to differentiate it from other common disorders). It may be used in community settings by mental health professionals as part of the diagnostic process, or to formalize diagnosis in the context of research. Use of the CAMCOG provides the means for ongoing neuropsychological evaluation and informs future support and intervention strategies.

Down Syndrome, Neurodegeneration and Dementia

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889742091
Total Pages : 145 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Down Syndrome, Neurodegeneration and Dementia by : Sylvia Eva Perez

Download or read book Down Syndrome, Neurodegeneration and Dementia written by Sylvia Eva Perez and published by Frontiers Media SA. This book was released on 2022-01-27 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Down Syndrome

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Author :
Publisher : Wiley-Liss
ISBN 13 :
Total Pages : 320 pages
Book Rating : 4.4/5 (91 download)

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Book Synopsis Down Syndrome by : Lynn Nadel

Download or read book Down Syndrome written by Lynn Nadel and published by Wiley-Liss. This book was released on 1995-02-20 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in medicine are allowing people with Down syndrome to live longer and more productively - while at the same time creating new medical and social challenges for them and the people who provide their care. Down Syndrome: Living and Learning in the Community, which was written under the auspices of the National Down Syndrome Society, provides long-awaited, state-of-the-art information and advice about the disease. This book will prove an invaluable tool for parents and health care professionals, enabling people with Down syndrome to cope with the problems they face and participate to the fullest in community life.

Therapies and Rehabilitation in Down Syndrome

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 9780470319970
Total Pages : 228 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Therapies and Rehabilitation in Down Syndrome by : Jean-Adolphe Rondal, PhD

Download or read book Therapies and Rehabilitation in Down Syndrome written by Jean-Adolphe Rondal, PhD and published by John Wiley & Sons. This book was released on 2007-04-04 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Therapies and Rehabilitation in Down Syndrome covers the entire lifespan of a DS patient, from infancy to 60 years and beyond, focusing not simply on identifying problems, but providing a detailed look at major therapeutic approaches. Discussion includes future genetic therapy, questions of quality of life, hormone and other therapies for medical problems, prevention and treatment of normal and pathological aging, as well as psychomotoric rehabilitation. This is an important book not only for scientists concerned with various facets of DS, but practitioners looking for guidelines for therapies and clinical application of research findings.

Neurological Perspective on the Aging in Down's Syndrome and Its Relationship to Alzheimer's Disease

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Author :
Publisher :
ISBN 13 :
Total Pages : 120 pages
Book Rating : 4.:/5 (334 download)

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Book Synopsis Neurological Perspective on the Aging in Down's Syndrome and Its Relationship to Alzheimer's Disease by : Christine Jonker

Download or read book Neurological Perspective on the Aging in Down's Syndrome and Its Relationship to Alzheimer's Disease written by Christine Jonker and published by . This book was released on 1995 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Down Syndrome

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Author :
Publisher : Lulu.com
ISBN 13 : 0979496233
Total Pages : 591 pages
Book Rating : 4.9/5 (794 download)

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Book Synopsis Down Syndrome by : Qadoshyah Fish

Download or read book Down Syndrome written by Qadoshyah Fish and published by Lulu.com. This book was released on 2008-11 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: People with Down syndrome can do a lot; this is the reality. We will share with you, in this book, stories from people with Down syndrome who have excelled in many areas and live lives like many other people who do not have Down syndrome. We will also share with you stories about those with Down syndrome who have had medical problems and issues to deal with, yet give joy to those they come in contact with. -- Preface.

Alzheimer’s Disease

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Author :
Publisher : Springer
ISBN 13 :
Total Pages : 424 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Alzheimer’s Disease by : Harvey J. Altman

Download or read book Alzheimer’s Disease written by Harvey J. Altman and published by Springer. This book was released on 1987-12-31 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Proceedings of a National Conference on Alzheimer's Disease and Dementia: problems, prospects, and perspectives, held April 10-12, 1986, in Detroit, Michigan" - T.p. verso.

Losing a Million Minds

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Author :
Publisher :
ISBN 13 :
Total Pages : 539 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Losing a Million Minds by :

Download or read book Losing a Million Minds written by and published by . This book was released on 1987 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Down's Syndrome and Dementia

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Author :
Publisher :
ISBN 13 : 9781905218080
Total Pages : 136 pages
Book Rating : 4.2/5 (18 download)

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Book Synopsis Down's Syndrome and Dementia by : Karen Dodd

Download or read book Down's Syndrome and Dementia written by Karen Dodd and published by . This book was released on 2009 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: A resource book for family carers, staff and other professionals to help them care more effectively for people with Down's syndrome and dementia.