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Alpha Hydroxy Acids In Enantioselective Syntheses
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Book Synopsis alpha-Hydroxy Acids in Enantioselective Syntheses by : Gary M. Coppola
Download or read book alpha-Hydroxy Acids in Enantioselective Syntheses written by Gary M. Coppola and published by Wiley-VCH. This book was released on 1997-03-27 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gary M. Coppola Herbert F. Schuster alpha;-Hydroxy Acids in Enantioselective Syntheses An ideal synthesis starts with readily accessible reagents and yields the target molecules in high optical purity. The naturally available alpha;-hydroxy acids, lactic, malic, mandelic and tartaric acids, provide the chemist with chiral building blocks for the introduction of one or more asymmetric centers into an organic molecule. This book not only supplies a comprehensive discussion of useful reactions but also demonstrates how complex molecules can have their origin in simple, readily accessible chirally pure starting materials. The authors, both practicing medicinal research chemists, aim at providing information for the design and synthesis of chiral molecules. A particularly attractive feature of this text is the excellent schemes used to illustrate the crucial transformations. All structures are represented in their absolute stereochemistry. Mechanisms as well as insights into the execution of a synthetic pathway are discussed concisely, with a focus on practical aspects. The authors have drawn on their years of writing experience to supply graduate students, research chemists and teachers alike with a gold mine of useful chemistry. Every synthetic chemist will want to have this invaluable resource at his or her disposal.
Book Synopsis Electrophilic Asymmetric Synthesis of A-hydroxy Acids and A-hydroxy Acid Derivatives by : Jerry Wayne Ludwig
Download or read book Electrophilic Asymmetric Synthesis of A-hydroxy Acids and A-hydroxy Acid Derivatives written by Jerry Wayne Ludwig and published by . This book was released on 1984 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Enantioselective Synthesis of Beta-Amino Acids by : Eusebio Juaristi
Download or read book Enantioselective Synthesis of Beta-Amino Acids written by Eusebio Juaristi and published by John Wiley & Sons. This book was released on 2005-05-06 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers all facets of the synthesis of ß-amino acids As evidenced by an exponential increase in the literature published on the subject, interest in ß-amino acids has grown over the past several years. With major pharmaceutical applications, these amino acids are now studied across multiple lines of research, including combinatorial chemistry, medicinal chemistry, molecular design, proteomics, and others. This Second Edition of Enantioselective Synthesis of ß-Amino Acids updates reviews included in the First Edition while also covering new developments since its publication. The book presents detailed discussions of the most important methods for the synthesis of ß-amino acids. In most cases, the lead chemist who originally developed a method provides an authoritative description of it. In addition, Enantioselective Synthesis of ß-Amino Acids, Second Edition: * Features introductory overviews on the structural types of relevant ß-amino acid targets and salient ß-amino acids present in natural products * Dedicates several chapters to advances in the synthesis of oligomers from ß-amino acids * Includes general and practical procedures for the preparation of ß-amino acids in each chapter * Discusses the most important methods that have been recently developed for the asymmetric synthesis of cyclic and open-chain ß-amino acids * Includes a report on the preparation of libraries of enantiopure ß-amino acids using combinatorial approaches The only book of its kind available today, Enantioselective Synthesis of ß-Amino Acids, Second Edition offers upper-level students and professionals an essential resource for pharmaceutical development, medicinal chemistry, and biochemistry.
Book Synopsis Asymmetric Synthesis of Beta-amino-alpha-hydroxy Acids by : Mark E. Bunnage
Download or read book Asymmetric Synthesis of Beta-amino-alpha-hydroxy Acids written by Mark E. Bunnage and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Asymmetric Synthesis of [beta]-amino-[alpha]-hydroxy Acids by : Mark E. Bunnage
Download or read book The Asymmetric Synthesis of [beta]-amino-[alpha]-hydroxy Acids written by Mark E. Bunnage and published by . This book was released on 1993 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Asymmetric Synthesis of [alpha]-hydroxy Acids, Glycols, and Tertiary Alcohols Via 1,3-oxathianes Derived from (+)-pulegone by : Joseph E. Lynch
Download or read book Asymmetric Synthesis of [alpha]-hydroxy Acids, Glycols, and Tertiary Alcohols Via 1,3-oxathianes Derived from (+)-pulegone written by Joseph E. Lynch and published by . This book was released on 1982 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Transition Metal Catalyzed Enantioselective Allylic Substitution in Organic Synthesis by : Uli Kazmaier
Download or read book Transition Metal Catalyzed Enantioselective Allylic Substitution in Organic Synthesis written by Uli Kazmaier and published by Springer Science & Business Media. This book was released on 2011-10-29 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Giovanni Poli, Guillaume Prestat, Frédéric Liron, Claire Kammerer-Pentier: Selectivity in Palladium Catalyzed Allylic Substitution.- Jonatan Kleimark and Per-Ola Norrby: Computational Insights into Palladium-mediated Allylic Substitution Reactions.- Ludovic Milhau, Patrick J. Guiry: Palladium-catalyzed enantioselective allylic substitution.- Wen-Bo Liu, Ji-Bao Xia, Shu-Li You: Iridium-Catalyzed Asymmetric Allylic Substitutions.- Christina Moberg: Molybdenum- and Tungsten-Catalyzed Enantioselective Allylic Substitutions.- Jean-Baptiste Langlois, Alexandre Alexakis: Copper-catalyzed enantioselective allylic substitution.- Jeanne-Marie Begouin, Johannes E. M. N. Klein, Daniel Weickmann, B. Plietker: Allylic Substitutions Catalyzed by Miscellaneous Metals.- Barry M. Trost, Matthew L. Crawley: Enantioselective Allylic Substitutions in Natural Product Synthesis.
Book Synopsis Molybdenum and Palladium Catalyzed Asymmetric Allylic Alkylation of Prochiral Nucleophiles by : Maurizio Franzini
Download or read book Molybdenum and Palladium Catalyzed Asymmetric Allylic Alkylation of Prochiral Nucleophiles written by Maurizio Franzini and published by . This book was released on 2005 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Organocatalytic Enantioselective Syntheses of [alpha]-hydroxy Phosphinates/phosphonates, 3, 4-dihydro-2H-pyran Derivatives and Mannich Bases by : Wijesooriya Gunawardhana Mahawaduge Sandun Perera
Download or read book Organocatalytic Enantioselective Syntheses of [alpha]-hydroxy Phosphinates/phosphonates, 3, 4-dihydro-2H-pyran Derivatives and Mannich Bases written by Wijesooriya Gunawardhana Mahawaduge Sandun Perera and published by . This book was released on 2013 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Asymmetric Synthesis of Β-amino-α-hydroxy Acids by : Mark E. Bunnage
Download or read book The Asymmetric Synthesis of Β-amino-α-hydroxy Acids written by Mark E. Bunnage and published by . This book was released on 1993 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Chiral Reagents for Asymmetric Synthesis by : Leo A. Paquette
Download or read book Chiral Reagents for Asymmetric Synthesis written by Leo A. Paquette and published by John Wiley & Sons. This book was released on 2003-08-01 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Derived from the renowned, Encyclopedia of Reagents for Organic Synthesis (EROS), the related editors have created a new handbook which focuses on chiral reagents used in asymmetric synthesis and is designed for the chemist at the bench. This new handbook follows the same format as the Encyclopedia, including an introduction and an alphabetical arrangement of the reagents. As chiral reagents are the key for the successful asymmetric synthesis, choosing the right reagents is essential, in this handy reference the editors give details on how to prepare, store and use the reagents as well as providing key reactions to demonstrate where reagents have been successfully used. Comprehensive information on 226 reagents Covers 64 reagents which were not included in EROS All information in one easy to use volume – at an affordable price All reagents included will be added to e-EROS – please visit the site where you can gain access to over 50,000 reactions and 3,800 of the most frequently consulted reagents. Visit: www.interscience.wiley.com/eros
Book Synopsis Enantioselective Synthesis of [alpha]-fluoro-[beta]-hydroxy Esters and Amides by : Yanyun Liu
Download or read book Enantioselective Synthesis of [alpha]-fluoro-[beta]-hydroxy Esters and Amides written by Yanyun Liu and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Enantioselective Synthesis Using Biological Systems by : Robert Azerad
Download or read book Enantioselective Synthesis Using Biological Systems written by Robert Azerad and published by CRC Press. This book was released on 1990 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Asymmetric Synthesis in Organophosphorus Chemistry by : Oleg I. Kolodiazhnyi
Download or read book Asymmetric Synthesis in Organophosphorus Chemistry written by Oleg I. Kolodiazhnyi and published by John Wiley & Sons. This book was released on 2016-09-20 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by one of the leading experts in the field, this is the only comprehensive overview of chiral organophosphorus compounds, from asymmetric synthesis to catalysis and pharmacological applications. As such, this unique reference covers the chemical background as well as spectroscopical analysis of phosphorus compounds, and thoroughly describes all the various synthetic strategies for these substances. Metal-, organo- and biocatalyzed reactions for the introduction of phosphorus are explained as are asymmetric oxidation and reduction methods for the preparation of all possible oxidation states of phosphorus. The text also includes industrial applications for these compounds. Of particular interest to chemists working in the field of asymmetric synthesis, as well as to the pharmaceutical industry due to the increasing number of phosphorous-containing drugs.
Book Synopsis Direct Asymmetric Conversion of Aldehydes to Α-hydroxy Acids by : Jae-won Lee
Download or read book Direct Asymmetric Conversion of Aldehydes to Α-hydroxy Acids written by Jae-won Lee and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Enantioselective Chemical Synthesis by : Elias J. Corey
Download or read book Enantioselective Chemical Synthesis written by Elias J. Corey and published by Elsevier. This book was released on 2013-10-23 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by world-renowned and best-selling experts, Nobel Laureate E. J. Corey and Laszlo Kurti, Enantioselective Chemical Synthesis offers an authoritative and comprehensive overview of the field's progress; the processes and tools for key formations; future development for complex, stereocontrolled (enantiomeric or diastereoisomeric) molecules; and valuable examples of multi-step syntheses. Utilizing a color-coded scheme to illustrate chemical transformations, Enantioselective Chemical Synthesis provides clear explanation and guidance through vital asymmetrical syntheses and insight into the next steps for the field. Researchers, professionals, and academics will benefit from this valuable, thorough, and unique resource. - In Part I, the authors present clearly, comprehensively and concisely the most useful enantioselective processes available to synthetic chemists. - Part II provides an extensive discussion of the most logical ways to apply these new enantioselective methods to the planning of syntheses of stereochemically complex molecules. This hitherto neglected area is essential for the advancement of enantioselective synthesis to a more rational and powerful level. - Part III describes in detail many reaction sequences which have been used successfully for the construction of a wide variety of complex target molecules - Clearly explains stereochemical synthesis in theory and practice - Provides a handy tool box for scientists wishing to understand and apply chiral chemical synthesis - Describes almost 50 real life examples of asymmetric synthesis in practice and examines how the chiral centers were introduced at key synthetic stages
Book Synopsis Comprehensive Organic Chemistry Experiments for the Laboratory Classroom by : Carlos A M Afonso
Download or read book Comprehensive Organic Chemistry Experiments for the Laboratory Classroom written by Carlos A M Afonso and published by Royal Society of Chemistry. This book was released on 2020-08-28 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: This expansive and practical textbook contains organic chemistry experiments for teaching in the laboratory at the undergraduate level covering a range of functional group transformations and key organic reactions.The editorial team have collected contributions from around the world and standardized them for publication. Each experiment will explore a modern chemistry scenario, such as: sustainable chemistry; application in the pharmaceutical industry; catalysis and material sciences, to name a few. All the experiments will be complemented with a set of questions to challenge the students and a section for the instructors, concerning the results obtained and advice on getting the best outcome from the experiment. A section covering practical aspects with tips and advice for the instructors, together with the results obtained in the laboratory by students, has been compiled for each experiment. Targeted at professors and lecturers in chemistry, this useful text will provide up to date experiments putting the science into context for the students.
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